diazepam has been researched along with Alcohol Drinking in 76 studies
Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.
Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Part 1: Anxiety at 3 hours was significantly lower following minocycline (20 mg/kg i." | 7.88 | Minocycline in Alcohol Withdrawal Induced Anxiety and Alcohol Relapse in Rats. ( Gajbhiye, SV; Petare, A; Potey, AV; Shankar, A; Tripathi, RK, 2018) |
| "Deramciclane appears to be a safe and well-tolerated drug and we suggest that it might be useful in the treatment of anxiety in alcoholics." | 5.32 | Comparison of deramciclane to benzodiazepine agonists in behavioural activity of mice and in alcohol drinking of alcohol-preferring rats. ( Honkanen, A; Ingman, K; Korpi, ER; Sallinen, J, 2004) |
| "Part 1: Anxiety at 3 hours was significantly lower following minocycline (20 mg/kg i." | 3.88 | Minocycline in Alcohol Withdrawal Induced Anxiety and Alcohol Relapse in Rats. ( Gajbhiye, SV; Petare, A; Potey, AV; Shankar, A; Tripathi, RK, 2018) |
| " The authors present three patients with alcoholism in whom diagnosis of panic was facilitated by intravenous lactate infusion, and whose symptoms were alleviated by clonazepam." | 3.68 | The diagnosis and treatment of panic disorder in alcoholics: three cases. ( Baron, DH; Ciraulo, DA; Sands, BF; Shader, RI, 1990) |
| "Lorazepam was used as rescue medication." | 2.82 | A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome. ( Girish, K; Manjunatha, R; Nagraj, M; Pandit, LV; Pundarikaksha, HP; Shruthi, R; Vasundara, K; Vijendra, R; Vikram Reddy, K, 2016) |
| "8); a lower daily benzodiazepine dosage at the start of tapering off (HR 1." | 2.72 | Predictors of long-term benzodiazepine abstinence in participants of a randomized controlled benzodiazepine withdrawal program. ( Breteler, MH; Gorgels, WJ; Mol, AJ; Mulder, J; van Balkom, AJ; van de Lisdonk, EH; Voshaar, RC; Zitman, FG, 2006) |
| "Twelve male problem drinkers (Alcohol Dependence Scale; ADS score > or =9) received oral diazepam (5 mg) and placebo, in a counterbalanced manner on separate sessions." | 2.71 | Low-dose diazepam primes motivation for alcohol and alcohol-related semantic networks in problem drinkers. ( Poulos, CX; Zack, M, 2004) |
| "Diazepam choice was also associated with more frequent recreational use of marijuana and stimulants." | 2.67 | Relationship between subjective effects and drug preferences: ethanol and diazepam. ( Chutuape, MA; de Wit, H, 1994) |
| "When remoxipride was combined with either ethanol or diazepam, there was a tendency for the effect to be additive." | 2.67 | Effects of remoxipride on psychomotor performance, alone and in combination with ethanol and diazepam. ( Mattila, ME; Mattila, MJ, 1990) |
| "Diazepam 20 mg was used up to three times per day, but didn't seem to improve or reduce the anxiety, agitation, visual or auditory hallucinations." | 1.48 | Delirium tremens in an AUD patient after an intrathecal baclofen pump induced total alcohol abstinence. ( Calvo, ME; Gunnarsson, T; Hao, M; Smith, L, 2018) |
| "Deramciclane appears to be a safe and well-tolerated drug and we suggest that it might be useful in the treatment of anxiety in alcoholics." | 1.32 | Comparison of deramciclane to benzodiazepine agonists in behavioural activity of mice and in alcohol drinking of alcohol-preferring rats. ( Honkanen, A; Ingman, K; Korpi, ER; Sallinen, J, 2004) |
| "When establishing threshold values for "driving under the influence of centrally acting compounds" it must be considered that many parameters have an important influence on the pharmacokinetic properties (e." | 1.29 | [Determination of limit values for "safe driving" in street traffic with reference to centrally active drugs from the pharmacokinetic and pharmacodynamic viewpoint]. ( Schütz, H; Weiler, G, 1993) |
| "Preference for diazepam was assessed in 18 light and 12 moderate social drinkers using a cumulative dosing procedure." | 1.28 | Reinforcing and subjective effects of diazepam in nondrug-abusing volunteers. ( deWit, H; Johanson, CE; Pierri, J, 1989) |
| "Diazepam was found in 16 of the 18 subjects in whom psychotropic drugs were detected." | 1.26 | Role of drugs in traffic accidents. ( Alha, A; Ertama, L; Honkanen, R; Karlsson, M; Kiviluoto, O; Linnoila, M; Lukkari, I; Puro, M, 1980) |
| " Diazepam (Valium) dosage (5 milligrams per kilogram of body weight) during the period ow withdrawal serves to maintain undiminished such alcohol self-administration." | 1.26 | Diazepam maintenance of alcohol preference during alcohol withdrawal. ( Deutsch, JA; Walton, NY, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (42.11) | 18.7374 |
| 1990's | 24 (31.58) | 18.2507 |
| 2000's | 13 (17.11) | 29.6817 |
| 2010's | 7 (9.21) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martinez, L | 1 |
| Vorspan, F | 1 |
| Declèves, X | 1 |
| Azuar, J | 1 |
| Fortias, M | 1 |
| Questel, F | 1 |
| Dereux, A | 1 |
| Grichy, L | 1 |
| Barreteau, H | 1 |
| Bellivier, F | 1 |
| Lépine, JP | 1 |
| Bloch, V | 1 |
| Gajbhiye, SV | 1 |
| Tripathi, RK | 1 |
| Petare, A | 1 |
| Potey, AV | 1 |
| Shankar, A | 1 |
| Calvo, ME | 1 |
| Gunnarsson, T | 1 |
| Smith, L | 1 |
| Hao, M | 1 |
| Blackburn, DJ | 1 |
| Alix, JJ | 1 |
| Sarrigiannis, P | 1 |
| Hoggard, N | 1 |
| Bandmann, O | 1 |
| de Timary, P | 1 |
| Cordovil de Sousa Uva, M | 1 |
| Denoël, C | 1 |
| Hebborn, L | 1 |
| Derely, M | 1 |
| Desseilles, M | 1 |
| Luminet, O | 1 |
| Girish, K | 1 |
| Vikram Reddy, K | 1 |
| Pandit, LV | 1 |
| Pundarikaksha, HP | 1 |
| Vijendra, R | 1 |
| Vasundara, K | 1 |
| Manjunatha, R | 1 |
| Nagraj, M | 1 |
| Shruthi, R | 1 |
| van Rijn, RM | 1 |
| Brissett, DI | 1 |
| Whistler, JL | 1 |
| Bråthen, G | 1 |
| Ingman, K | 1 |
| Sallinen, J | 1 |
| Honkanen, A | 1 |
| Korpi, ER | 2 |
| Poulos, CX | 1 |
| Zack, M | 1 |
| Martijena, ID | 1 |
| Bustos, SG | 1 |
| Bertotto, ME | 1 |
| Molina, VA | 1 |
| Shram, MJ | 1 |
| Bahroos, M | 1 |
| Beleskey, JI | 1 |
| Tampakeras, M | 1 |
| Lê, AD | 1 |
| Tomkins, DM | 1 |
| Charlton, BG | 1 |
| Croft, AP | 1 |
| Brooks, SP | 1 |
| Cole, J | 1 |
| Little, HJ | 1 |
| Kurzthaler, I | 1 |
| Wambacher, M | 1 |
| Golser, K | 1 |
| Sperner, G | 1 |
| Sperner-Unterweger, B | 1 |
| Haidekker, A | 1 |
| Pavlic, M | 1 |
| Kemmler, G | 1 |
| Fleischhacker, WW | 1 |
| Voshaar, RC | 1 |
| Gorgels, WJ | 1 |
| Mol, AJ | 1 |
| van Balkom, AJ | 1 |
| Mulder, J | 1 |
| van de Lisdonk, EH | 1 |
| Breteler, MH | 1 |
| Zitman, FG | 1 |
| Besheer, J | 1 |
| Lepoutre, V | 1 |
| Mole, B | 1 |
| Hodge, CW | 1 |
| Longstreth, GF | 1 |
| O'Brien, PM | 1 |
| Youkeles, LF | 1 |
| Fuchs, V | 1 |
| Burbes, E | 1 |
| Coper, H | 1 |
| Cook, PJ | 1 |
| Flanagan, R | 1 |
| James, IM | 1 |
| Tennant, FS | 1 |
| Rawson, RA | 1 |
| Cohen, A | 1 |
| Tarver, A | 1 |
| Clabough, D | 1 |
| Hargreaves, WA | 1 |
| Tyler, J | 1 |
| Weinberg, JA | 1 |
| Sorensen, JL | 1 |
| Benowitz, N | 1 |
| Ryser, PE | 1 |
| Vine, J | 1 |
| Watson, TR | 1 |
| Pristach, CA | 1 |
| Smith, CM | 2 |
| Whitney, RB | 1 |
| Job, RF | 1 |
| Ungerleider, JT | 1 |
| Lundberg, GD | 1 |
| Sunshine, I | 1 |
| Walberg, CB | 1 |
| Doenecke, AL | 1 |
| Heuermann, RC | 1 |
| Weimer, SR | 1 |
| Honkanen, R | 1 |
| Ertama, L | 1 |
| Linnoila, M | 2 |
| Alha, A | 1 |
| Lukkari, I | 1 |
| Karlsson, M | 1 |
| Kiviluoto, O | 1 |
| Puro, M | 1 |
| Cohen, SI | 1 |
| de Wit, H | 5 |
| Bodker, B | 1 |
| Krull, KR | 1 |
| Smith, LT | 1 |
| Parsons, OA | 1 |
| Dudish, S | 1 |
| Ambre, J | 1 |
| Doty, P | 1 |
| Chutuape, MA | 1 |
| Schütz, H | 1 |
| Weiler, G | 1 |
| Evans, SM | 1 |
| Griffiths, RR | 1 |
| Iwinska, K | 1 |
| Jankowska, E | 1 |
| Stefanski, R | 1 |
| Bienkowski, P | 2 |
| Kostowski, W | 2 |
| Söderpalm, AH | 1 |
| Hansen, S | 2 |
| Borde, N | 1 |
| Jaffard, R | 1 |
| Béracochéa, D | 1 |
| Samer Abdalla, M | 1 |
| Fahlke, C | 1 |
| Colombo, G | 1 |
| Agabio, R | 1 |
| Carai, MA | 1 |
| Lobina, C | 1 |
| Pani, M | 1 |
| Reali, R | 1 |
| Vacca, G | 1 |
| Gessa, GL | 1 |
| Krzascik, P | 1 |
| Koros, E | 1 |
| Scinska, A | 1 |
| Danysz, W | 1 |
| Schuckit, MA | 6 |
| Smith, TL | 1 |
| Jatlow, P | 1 |
| Dobular, K | 1 |
| Bailey, D | 1 |
| Palva, ES | 1 |
| Curry, SH | 1 |
| Deutsch, JA | 1 |
| Walton, NY | 1 |
| Ferko, AP | 1 |
| Bobyock, E | 1 |
| Chernick, WS | 1 |
| Thompson, WL | 1 |
| Uusi-Oukari, M | 1 |
| Wegelius, K | 1 |
| Casanova, M | 1 |
| Zito, M | 1 |
| Kleinman, JE | 1 |
| Allan, AM | 1 |
| Mayes, GG | 1 |
| Draski, LJ | 1 |
| Gewiss, M | 1 |
| Heidbreder, C | 1 |
| Opsomer, L | 1 |
| Durbin, P | 1 |
| De Witte, P | 1 |
| Duthie, LA | 3 |
| Mahler, HI | 2 |
| Irwin, M | 4 |
| Monteiro, MG | 4 |
| Hauger, RL | 1 |
| Nielsen, LM | 1 |
| Nielsen, SL | 1 |
| Christensen, LQ | 1 |
| Steentoft, A | 1 |
| Worm, K | 1 |
| Mattila, MJ | 1 |
| Mattila, ME | 1 |
| Klein, JL | 1 |
| Hauger, R | 1 |
| Baron, DH | 1 |
| Sands, BF | 1 |
| Ciraulo, DA | 1 |
| Shader, RI | 2 |
| deWit, H | 1 |
| Pierri, J | 1 |
| Johanson, CE | 1 |
| Moser, L | 1 |
| Ellison, G | 1 |
| Potthoff, A | 1 |
| Tilley, S | 1 |
| Weighill, VE | 1 |
| Eulitz, J | 1 |
| Krause, D | 1 |
| Herold, C | 1 |
| Brier, C | 1 |
| Koch, R | 1 |
| Forney, RB | 1 |
| Amit, Z | 2 |
| Cohen, J | 1 |
| Franck, G | 1 |
| Corcoran, ME | 1 |
| Charness, ME | 1 |
| Shizgal, P | 1 |
| Belfer, ML | 1 |
| Carroll, M | 1 |
| Harmatz, JS | 1 |
| Seiler, K | 1 |
| Duckert, F | 1 |
| Milner, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Use of Diphenhydramine as an Adjunctive Sedative for Colonoscopy in Patients Chronically on Opioids[NCT01967433] | Phase 4 | 120 participants (Actual) | Interventional | 2013-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Patient were also asked to rate amnesia on a 10 point scale 24 after discharge. minimum= 0 (worse) maximum =10 (better) (NCT01967433)
Timeframe: At about 24 after the procedure
| Intervention | score on a 10 point point scale (Mean) |
|---|---|
| Placebo | 7.8 |
| Diphenhydramine | 6.5 |
"At 24 hr follow up patients were asked to rate the level of pain during the procedure using 10 point scale.~10 point visual analogue scale minimum= 0 (better) maximum =10 (worse)" (NCT01967433)
Timeframe: About 24 hours after the procedure
| Intervention | score on a scale (Mean) |
|---|---|
| Diphenhydramine | 2.0 |
| Placebo | 3.09 |
Moderate sedation (using the American Society of Anesthesiologists definition of maintaining purposeful response to verbal or tactile stimulation, adequate ventilation requiring no airway protection, and maintenance of cardiovascular function) was then achieved using incremental doses of the combination of intravenous midazolam (1 mg) and fentanyl (25 μg) given every 2 to 3 minutes. To minimize any crossover, additional diphenhydramine was not permitted. (NCT01967433)
Timeframe: From induction (first dose of sedative) to end of procedure
| Intervention | (μg) (Mean) |
|---|---|
| Diphenhydramine | 125.4 |
| Placebo | 126.9 |
Moderate sedation (using the American Society of Anesthesiologists definition of maintaining purposeful response to verbal or tactile stimulation, adequate ventilation requiring no airway protection, and maintenance of cardiovascular function) was then achieved using incremental doses of the combination of intravenous midazolam (1 mg) and fentanyl (25 μg) given every 2 to 3 minutes. To minimize any crossover, additional diphenhydramine was not permitted. (NCT01967433)
Timeframe: From induction (first dose of sedative) to end of procedure
| Intervention | mg (Mean) |
|---|---|
| Diphenhydramine | 4.9 |
| Placebo | 5.0 |
Induction period (time from first dose of fentanyl to scope insertion), procedural time (time from scope insertion to scope out), and recovery time (time from scope out to discharge) were recorded by the nursing staff in their standard documentation. (NCT01967433)
Timeframe: Time from induction (first dose of sedative) to discharge
| Intervention | minutes (Mean) | ||
|---|---|---|---|
| Procedure time | Recovery | Induction | |
| Diphenhydramine | 34.8 | 34.4 | 6.4 |
| Placebo | 34.7 | 32.4 | 6.3 |
Following adverse events will be recorded: (1)Hypoxia defined as O2 saturation less than 89% lasting for more than 30 seconds, (2)hypotension defined as systolic BP less than 90 mmhg and (3)use of reversal agents i.e Naloxone or Flumazenil (NCT01967433)
Timeframe: From induction (first dose of sedative) to discharge
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Hypotension | Hypertension | Desaturation | Apnea | Arrhythmia | Reversal agent use | Tachypnea | |
| Diphenhydramine | 12 | 5 | 0 | 0 | 0 | 0 | 0 |
| Placebo | 22 | 3 | 0 | 0 | 0 | 0 | 0 |
"Quality of sedation will be accessed by the nurse and the physician at the end of procedure.~Name: 10 point visual analogue scale Minimum score: 1 (worse) Maximum score: 10 (better)" (NCT01967433)
Timeframe: During the colonoscopy and 24 hours after discharge
| Intervention | score on a scale (Mean) | |
|---|---|---|
| Physician rating | Nurse rating | |
| Diphenhydramine | 6.2 | 5.6 |
| Placebo | 5.3 | 5.1 |
1 review available for diazepam and Alcohol Drinking
| Article | Year |
|---|---|
[Alcohol and epilepsy].
Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Anticonvulsants; Benzodiazepines; Diazepam; Epilepsy; | 2003 |
17 trials available for diazepam and Alcohol Drinking
| Article | Year |
|---|---|
A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome.
Topics: Adult; Alcohol Drinking; Baclofen; Chlordiazepoxide; Diazepam; Humans; Lorazepam; Male; Middle Aged; | 2016 |
Low-dose diazepam primes motivation for alcohol and alcohol-related semantic networks in problem drinkers.
Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Diazepam; Double-Blind Method; GABA Modul | 2004 |
Predictors of long-term benzodiazepine abstinence in participants of a randomized controlled benzodiazepine withdrawal program.
Topics: Aged; Alcohol Drinking; Anti-Anxiety Agents; Benzodiazepines; Cognitive Behavioral Therapy; Combined | 2006 |
Personality and drug preferences in normal volunteers.
Topics: Adult; Alcohol Drinking; Attitude; Choice Behavior; Diazepam; Double-Blind Method; Female; Gender Id | 1994 |
Simple reaction time event-related potentials: effects of alcohol and diazepam.
Topics: Adult; Alcohol Drinking; Brain; Diazepam; Electroencephalography; Ethanol; Evoked Potentials; Humans | 1994 |
Subjective and behavioral effects of diazepam depend on its rate of onset.
Topics: Adult; Affect; Alcohol Drinking; Behavior; Breath Tests; Cognition; Diazepam; Double-Blind Method; E | 1993 |
Preference for ethanol and diazepam in light and moderate social drinkers: a within-subjects study.
Topics: Adult; Affect; Alcohol Drinking; Diazepam; Double-Blind Method; Female; Humans; Male; Psychomotor Pe | 1994 |
Relationship between subjective effects and drug preferences: ethanol and diazepam.
Topics: Adult; Affect; Alcohol Drinking; Alcoholic Intoxication; Arousal; Choice Behavior; Diazepam; Dose-Re | 1994 |
Preference for diazepam, but not buspirone, in moderate drinkers.
Topics: Adult; Alcohol Drinking; Anxiety; Buspirone; Diazepam; Fatigue; Female; Humans; Male; Time Factors | 1996 |
The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders.
Topics: Adaptation, Psychological; Adolescent; Adult; Alcohol Drinking; Alcoholism; Arousal; Child of Impair | 2000 |
Effect of active metabolites of chlordiazepoxide and diazepam, alone or in combination with alcohol, on psychomotor skills related to driving.
Topics: Adult; Alcohol Drinking; Automobile Driving; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; D | 1978 |
Subjective feelings and changes in body sway following diazepam in sons of alcoholics and control subjects.
Topics: Adult; Alcohol Drinking; Alcoholism; Child of Impaired Parents; Diazepam; Dose-Response Relationship | 1991 |
Response of three hormones to diazepam challenge in sons of alcoholics and controls.
Topics: Adult; Alcohol Drinking; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Growth Hormone; Hum | 1991 |
Effects of remoxipride on psychomotor performance, alone and in combination with ethanol and diazepam.
Topics: Administration, Oral; Adult; Alcohol Drinking; Antipsychotic Agents; Arousal; Attention; Benzamides; | 1990 |
Growth hormone response to intravenous diazepam and placebo in 82 healthy men.
Topics: Adolescent; Adult; Alcohol Drinking; Diazepam; Dose-Response Relationship, Drug; Growth Hormone; Hum | 1990 |
[Effect of astemizole on psychophysical performance].
Topics: Alcohol Drinking; Arousal; Astemizole; Automobile Driving; Benzimidazoles; Clinical Trials as Topic; | 1985 |
International seminar research on alcohol, drugs and driving.
Topics: Alcohol Drinking; Auditory Perception; Automobile Driving; Caffeine; Chlordiazepoxide; Clinical Tria | 1973 |
58 other studies available for diazepam and Alcohol Drinking
| Article | Year |
|---|---|
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high-dosage baclofen.
Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Baclofen; Diazepam; Female; GABA Modulato | 2018 |
Minocycline in Alcohol Withdrawal Induced Anxiety and Alcohol Relapse in Rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Anti-Bacterial Agents; Anxiety; Diazepam; Disease Models, Ani | 2018 |
Delirium tremens in an AUD patient after an intrathecal baclofen pump induced total alcohol abstinence.
Topics: Alcohol Abstinence; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Baclofen; Diazepam; H | 2018 |
Delayed toxic-hypoxic encephalopathy.
Topics: Adult; Alcohol Drinking; Diagnosis, Differential; Diazepam; Humans; Hypoxia, Brain; Male; Marijuana | 2013 |
The associations between self-consciousness, depressive state and craving to drink among alcohol dependent patients undergoing protracted withdrawal.
Topics: Adult; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Depression; Diazepam; Female; Humans; Male | 2013 |
Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety.
Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benza | 2010 |
Comparison of deramciclane to benzodiazepine agonists in behavioural activity of mice and in alcohol drinking of alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Benzodiazepines; Camphanes; Diazepam; Dose-Response Relationship, Drug; G | 2004 |
Antidepressants attenuate both the enhanced ethanol intake and ethanol-induced anxiolytic effects in diazepam withdrawn rats.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety | 2005 |
Motor impairing effects of ethanol and diazepam in rats selectively bred for high and low ethanol consumption in a limited-access paradigm.
Topics: Alcohol Drinking; Animals; Breeding; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; Ma | 2004 |
Diazepam with your dinner, Sir? The lifestyle drug-substitution strategy: a radical alcohol policy.
Topics: Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Cannabis; Diazepam; Health Policy; Humans; Life S | 2005 |
Social defeat increases alcohol preference of C57BL/10 strain mice; effect prevented by a CCKB antagonist.
Topics: Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Diazepam; Indoles; Meglumine; Mice; Mi | 2005 |
Alcohol and/or benzodiazepine use: different accidents--different impacts?
Topics: Accidents; Adult; Age Factors; Aged; Alcohol Drinking; Anti-Anxiety Agents; Central Nervous System D | 2005 |
GABAA receptor regulation of voluntary ethanol drinking requires PKCepsilon.
Topics: Alcohol Drinking; Animals; Diazepam; Flumazenil; GABA Agonists; GABA Modulators; Hypnotics and Sedat | 2006 |
Determinants of the intravenous diazepam dose required for gastroscopy.
Topics: Age Factors; Alcohol Drinking; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationshi | 1980 |
The influence of haloperidol and aminooxyacetic acid on etonitazene, alcohol, diazepam and barbital consumption.
Topics: Acetates; Alcohol Drinking; Aminooxyacetic Acid; Animals; Barbital; Barbiturates; Benzimidazoles; Br | 1984 |
Diazepam tolerance: effect of age, regular sedation, and alcohol.
Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Diazepam; Dose-Response Relationship, Drug; | 1984 |
Methadone plasma levels and persistent drug abuse in high dose maintenance patients.
Topics: Alcohol Drinking; Diazepam; Dose-Response Relationship, Drug; Heroin Dependence; Humans; Methadone; | 1984 |
(--)-alpha-Acetylmethadol effects on alcohol and diazepam use, sexual function and cardiac function.
Topics: Adult; Alcohol Drinking; Blood Pressure; Diazepam; Electrocardiography; Heart; Heart Rate; Heroin De | 1983 |
Sex differences in substance abuse: 1976-1979.
Topics: Alcohol Drinking; Diazepam; Female; Heroin Dependence; Humans; Illicit Drugs; Male; Morphine Depende | 1983 |
Incidence of drug and alcohol intake in road traffic accident victims.
Topics: Accidents, Traffic; Alcohol Drinking; Anticonvulsants; Automobile Driving; Autopsy; Diazepam; Ethano | 1983 |
Alcohol withdrawal syndromes - prediction from detailed medical and drinking histories.
Topics: Adult; Aged; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Female; Flurazepam | 1983 |
Does diazepam affect driving ability?
Topics: Accidents, Traffic; Alcohol Drinking; Automobile Driving; Diazepam; Humans; Motor Skills | 1982 |
The Drug Abuse Warning Network (DAWN) Program. Toxicologic verification of 1,008 emergency room 'mentions'.
Topics: Alcohol Drinking; Diazepam; Drug and Narcotic Control; Emergency Service, Hospital; Heroin; Humans; | 1980 |
Treatment of haloperidol abuse with diphenhydramine.
Topics: Adolescent; Adult; Alcohol Drinking; Diazepam; Diphenhydramine; Female; Haloperidol; Humans; Male; S | 1980 |
Use of physiological monitoring in crisis interviewing: intervention in suicidal states.
Topics: Adult; Alcohol Drinking; Attitude of Health Personnel; Crisis Intervention; Defense Mechanisms; Diaz | 1980 |
Role of drugs in traffic accidents.
Topics: Accidents, Traffic; Alcohol Drinking; Diazepam; Drug-Related Side Effects and Adverse Reactions; Fin | 1980 |
Alcohol and benzodiazepines generate anxiety, panic and phobias.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; | 1995 |
[Determination of limit values for "safe driving" in street traffic with reference to centrally active drugs from the pharmacokinetic and pharmacodynamic viewpoint].
Topics: Adult; Aged; Aged, 80 and over; Alcohol Drinking; Automobile Driving; Diazepam; Dose-Response Relati | 1993 |
Differences between BDZ1 selective and non-selective GABAA/BDZ receptor ligands in discriminative stimulus and EtOH intake/preference paradigms.
Topics: Alcohol Drinking; Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Discrimination, Psychological; | 1996 |
Benzodiazepines enhance the consumption and palatability of alcohol in the rat.
Topics: Alcohol Drinking; Animals; Anti-Anxiety Agents; Brain; Chlordiazepoxide; Diazepam; Dose-Response Rel | 1998 |
Effects of chronic alcohol consumption or Diazepam administration on item recognition and temporal ordering in a spatial working memory task in mice.
Topics: Aging; Alcohol Drinking; Animals; Diazepam; Male; Memory; Mice; Mice, Inbred BALB C; Time Factors | 1998 |
Airline passenger dies after being sedated. ...or to potentiating effects on diazepam.
Topics: Aerospace Medicine; Aircraft; Alcohol Drinking; Diazepam; Drug Interactions; Humans; Hypnotics and S | 1999 |
Alcohol responsiveness, hyperreactivity, and motor restlessness in an animal model for attention-deficit hyperactivity disorder.
Topics: Alcohol Drinking; Animals; Attention Deficit Disorder with Hyperactivity; Brain Chemistry; Diazepam; | 1999 |
Different sensitivity to ethanol in alcohol-preferring sP and -nonpreferring sNP rats.
Topics: Alcohol Drinking; Animals; Central Nervous System Depressants; Depression, Chemical; Diazepam; Ethan | 2000 |
Effects of a novel uncompetitive NMDA receptor antagonist, MRZ 2/579 on ethanol self-administration and ethanol withdrawal seizures in the rat.
Topics: Alcohol Drinking; Alcohol Withdrawal Seizures; Animals; Conditioning, Operant; Cyclopentanes; Diazep | 2001 |
Serum diazepam concentrations in overdose. Their significance.
Topics: Alcohol Drinking; Anti-Anxiety Agents; Benzodiazepines; Chromatography, Gas; Clorazepate Dipotassium | 1979 |
Diazepam-ethanol interaction in humans: addition or potentiation?
Topics: Adolescent; Adult; Alcohol Drinking; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Eth | 1979 |
Diazepam maintenance of alcohol preference during alcohol withdrawal.
Topics: Alcohol Drinking; Alcoholism; Animals; Diazepam; Humans; Male; Rats; Substance Withdrawal Syndrome | 1977 |
A study on diazepam and postwithdrawal drinking of ethanol solution in rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Body Weight; Diazepam; Feeding Behavior; Humans; Male; Rats; | 1979 |
Management of alcohol withdrawal syndromes.
Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Dru | 1978 |
Cerebellar and frontal cortical benzodiazepine receptors in human alcoholics and chronically alcohol-drinking rats.
Topics: Adult; Alcohol Drinking; Alcoholism; Animals; Azides; Benzodiazepines; Brain; Cerebellum; Diazepam; | 1992 |
gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.
Topics: Alcohol Drinking; Animals; Chloride Channels; Diazepam; Female; Flunitrazepam; gamma-Aminobutyric Ac | 1991 |
Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour.
Topics: Acamprosate; Administration, Inhalation; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Anima | 1991 |
[Incidence of drugs and euphoretic agents among motorists on the roads of Denmark. A possible relationship to traffic safety].
Topics: Accidents, Traffic; Adult; Aged; Alcohol Drinking; Automobile Driving; Denmark; Diazepam; Female; Hu | 1991 |
Correlations between drinking intensity and reactions to ethanol and diazepam in healthy young men.
Topics: Adolescent; Adult; Alcohol Drinking; Diazepam; Ethanol; Humans; Hydrocortisone; Male; Neuropsycholog | 1991 |
The diagnosis and treatment of panic disorder in alcoholics: three cases.
Topics: Adult; Alcohol Drinking; Alcoholism; Anxiety Disorders; Clonazepam; Diazepam; Follow-Up Studies; Hum | 1990 |
Subjective feelings of anxiety in young men after ethanol and diazepam infusions.
Topics: Adult; Affect; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Anxiety; Diazepam; Dose-Response R | 1990 |
Reinforcing and subjective effects of diazepam in nondrug-abusing volunteers.
Topics: Adult; Alcohol Drinking; Choice Behavior; Diazepam; Female; Humans; Male; Personality; Psychomotor P | 1989 |
Increased alcohol intake induced by chronic stimulants: is "orality" involved?
Topics: Alcohol Drinking; Animals; Dextroamphetamine; Diazepam; Humans; Nicotine; Rats; Taste | 1987 |
How nurse therapists assess and contribute to the management of alcohol and sedative drug use among anxious patients.
Topics: Alcohol Drinking; Anxiety; Behavior Therapy; Counseling; Diazepam; Humans; Hypnotics and Sedatives; | 1986 |
[Alcohol, drugs and traffic laws. 2: Studies of the assessment of significant disability in automobile driving fitness caused by psychotropic drugs or alcohol and psychotropic drug combinations].
Topics: Accidents, Traffic; Adult; Alcohol Drinking; Arousal; Attention; Automobile Driving; Diazepam; Drug | 1986 |
The effect of hypothalamic stimulation on oral ingestion of diazepam in rats.
Topics: Alcohol Drinking; Animals; Diazepam; Drinking; Electric Stimulation; Hypothalamus; Male; Osmolar Con | 1974 |
[Neuro-psychiatric symptomatology in hypoglycemia].
Topics: Adenoma; Adult; Alcohol Drinking; Atropine; Bipolar Disorder; Coma; Diabetes Complications; Diazepam | 1974 |
Clinical depression of the central nervous system due to diazepam and chlordiazepoxide in relation to cigarette smoking and age.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Anxiety; Brain; Chlordiazepoxide; Depression, Chemical; | 1973 |
Intake of diazepam and hashish by alcohol preferring rats deprived of alcohol.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Cannabis; Diazepam; Drinking; Dronabinol; Electric St | 1973 |
Alcoholism in women.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anxiety; Chlordiazepoxide; Depression; Diazepam; Female; | 1971 |
Intoxication with phenprocoumon (marcoumar). Pharmacokinetics and side effects.
Topics: Adult; Alcohol Drinking; Blood Coagulation Tests; Coumarins; Diazepam; Humans; Male; Vitamin K; Vita | 1969 |
Drinking and driving in 753 general practice and psychiatric patients on psychotropic drugs.
Topics: Alcohol Drinking; Amitriptyline; Automobile Driving; Barbiturates; Chlordiazepoxide; Diazepam; Drug | 1969 |