diazepam and Alcohol Abuse studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

Excerpt	Relevance	Reference
"90 patients with alcoholism stage II suffering from secondary affective disorders (anxiety, depression) were divided into 4 groups: treated with GABA-B-receptor ligand baclofen (group 1), with sibazon (group 2), amitriptylin (group 3), placebo (group 4)."	9.07	[The use of baclofen for treating affective disorders in alcoholism]. ( Borodkin, IuS; Burakov, AM; Grinenko, AIa; Ivanov, VB; Karandashova, GF; Krupitskiĭ, EM; Lapin, IP, 1994)
"Minocycline attenuates alcohol withdrawal anxiety and disrupts alcohol relapse."	7.88	Minocycline in Alcohol Withdrawal Induced Anxiety and Alcohol Relapse in Rats. ( Gajbhiye, SV; Petare, A; Potey, AV; Shankar, A; Tripathi, RK, 2018)
" Lobeline increased the latency to the first seizure and decreased the percentage of seizures in a similar way as diazepam, used as control."	7.88	DNA damage and oxidative stress induced by seizures are decreased by anticonvulsant and neuroprotective effects of lobeline, a candidate to treat alcoholism. ( Boaretto, FBM; da Costa E Silva, LD; da Silva, LL; Hoffmann, C; Morás, AM; Moura, DJ; Pereira, P; Pflüger, P; Picada, JN; Regner, GG; Steffens, LR, 2018)
"Twenty-six adult patients with alcohol dependence (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision) who began an outpatient alcohol cessation program with an initial drinking goal of abstinence were enrolled in a 3-month, parallel, randomized (1:1 ratio), controlled, open-label, pilot trial."	6.84	Thirty- Versus Ten-Day Diazepam Treatment for Alcohol Detoxification and a Comparison of Drinking Patterns, Craving, and Anxiety for up to 12 Weeks: A "Proof-of-Concept" Open-Label Randomized Controlled Trial. ( Behal, H; Cottencin, O; Labreuche, J; Rolland, B; Simioni, N, 2017)
"In this study, we evaluated the effect of intrathecal and oral clonidine as supplements to spinal anesthesia with lidocaine in patients at risk of postoperative alcohol withdrawal syndrome (AWS)."	5.11	Intrathecal and oral clonidine as prophylaxis for postoperative alcohol withdrawal syndrome: a randomized double-blinded study. ( Axelsson, K; Berggren, L; Dobrydnjov, I; Holmström, B; Samarütel, J, 2004)
"90 patients with alcoholism stage II suffering from secondary affective disorders (anxiety, depression) were divided into 4 groups: treated with GABA-B-receptor ligand baclofen (group 1), with sibazon (group 2), amitriptylin (group 3), placebo (group 4)."	5.07	[The use of baclofen for treating affective disorders in alcoholism]. ( Borodkin, IuS; Burakov, AM; Grinenko, AIa; Ivanov, VB; Karandashova, GF; Krupitskiĭ, EM; Lapin, IP, 1994)
" To explore a possible role for this receptor complex in risk for alcoholism, and to determine whether risk for alcoholism is associated with risk for benzodiazepine abuse, the authors administered intravenous diazepam to 18 sons of male alcoholics (SOAs) and 18 control subjects."	5.07	Response to diazepam in sons of alcoholics. ( Cowley, DS; Godon, C; Greenblatt, DJ; Hommer, DW; Ries, R; Roy-Byrne, PP; Samson, HH; Walker, RD, 1992)
"The relationship between family history of alcoholism and risk for benzodiazepine abuse was examined by assessing the reinforcing and subjective effects of diazepam (DZ; 4-28 mg) in 14 normal (i."	5.07	Diazepam preference in males with and without an alcoholic first-degree relative. ( de Wit, H, 1991)
" Lobeline increased the latency to the first seizure and decreased the percentage of seizures in a similar way as diazepam, used as control."	3.88	DNA damage and oxidative stress induced by seizures are decreased by anticonvulsant and neuroprotective effects of lobeline, a candidate to treat alcoholism. ( Boaretto, FBM; da Costa E Silva, LD; da Silva, LL; Hoffmann, C; Morás, AM; Moura, DJ; Pereira, P; Pflüger, P; Picada, JN; Regner, GG; Steffens, LR, 2018)
"While some case reports indicate that high doses of propylene glycol (PG) may result in metabolic acidosis, there has been no large-scale study that evaluated the risk of metabolic acidosis in patients receiving PG-containing benzodiazepines for acute alcohol withdrawal."	3.88	Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model. ( Bodreau, C; Elbarbry, F; Farthing, K; Jahn, A, 2018)
"Minocycline attenuates alcohol withdrawal anxiety and disrupts alcohol relapse."	3.88	Minocycline in Alcohol Withdrawal Induced Anxiety and Alcohol Relapse in Rats. ( Gajbhiye, SV; Petare, A; Potey, AV; Shankar, A; Tripathi, RK, 2018)
" CIE is validated as a model for human alcohol withdrawal syndrome (AWS) by demonstrating increased level of anxiety; diazepam improved performance in the test."	3.72	Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. ( Cagetti, E; Liang, J; Olsen, RW; Spigelman, I, 2003)
"We report a 64-year-old male with granulocytopenia and dermatitis due to cyanamide treatment."	3.69	Cyanamide-induced granulocytopenia. ( Ajima, M; Hamano, K; Igarashi, A; Okazaki, R; Totsuka, Y; Urabe, A; Usuki, K, 1997)
" The authors present three patients with alcoholism in whom diagnosis of panic was facilitated by intravenous lactate infusion, and whose symptoms were alleviated by clonazepam."	3.68	The diagnosis and treatment of panic disorder in alcoholics: three cases. ( Baron, DH; Ciraulo, DA; Sands, BF; Shader, RI, 1990)
"The decreased sensitivity to the anxiolytic action of diazepam, BC-3-KEE, IME-6MEO-TGBC, IME-6MEO-DBC was shown in rats with experimental alcoholism."	3.67	[Anxiolytic action of beta-carbolines in rats]. ( Burov, IuV; Orekhov, SN; Vedernikova, NN, 1985)
"The effects of 5 mg of diazepam intravenously were assessed in 23 patients with liver disease, 10 of whom had clinical evidence either in the past or at the time of study of hepatic encephalopathy."	3.65	Clinical and electroencephalographic assessment of diazepam in liver disease. ( Knill-Jones, RP; Murray-Lyon, IM; Parkes, JD; Williams, R; Young, J, 1971)
"We enrolled 120 patients with alcohol use disorder who were randomly assigned to either treatment with vigabatrin (2g/day for 4 days) or placebo."	3.30	A Placebo-Controlled Randomized Trial of Vigabatrin in the Management of Acute Alcohol Withdrawal. ( Bonomo, Y; Collins, L; Lloyd-Jones, M; Norman, A; O'Neill, H; Ogden, E; Pastor, A; Williams, J, 2023)
"Baclofen can reduce the withdrawal symptoms during alcohol detoxification."	3.30	Baclofen during alcohol detoxification reduces the need for additional diazepam: a randomized placebo-controlled trial. ( Crunelle, CL; Jegham, S; Matthys, F; Vanderbruggen, N, 2023)
"Twenty-six adult patients with alcohol dependence (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision) who began an outpatient alcohol cessation program with an initial drinking goal of abstinence were enrolled in a 3-month, parallel, randomized (1:1 ratio), controlled, open-label, pilot trial."	2.84	Thirty- Versus Ten-Day Diazepam Treatment for Alcohol Detoxification and a Comparison of Drinking Patterns, Craving, and Anxiety for up to 12 Weeks: A "Proof-of-Concept" Open-Label Randomized Controlled Trial. ( Behal, H; Cottencin, O; Labreuche, J; Rolland, B; Simioni, N, 2017)
"Outcomes included incident seizures, delirium tremens, AW severity scores, adverse events, dropouts, dropouts from adverse events, length of hospital stay, use of additional medications, total benzodiazepine requirements, and death."	2.82	Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis. ( Bach, P; Bahji, A; Crockford, D; Danilewitz, M; Devoe, DJ; El-Guebaly, N; Saitz, R, 2022)
"Alcohol dependence is a public health problem worldwide, commonly associated with withdrawal symptoms for which diazepam is a frequently used drug."	2.82	Role of CYP2C19 gene polymorphism in acute alcohol withdrawal treatment with loading dose of diazepam in a South Indian population. ( Adithan, S; Chandrasekaran, A; Jose, M; Kattimani, S; Mathaiyan, J, 2016)
"Diazepam was administered using a similar regimen (from 130-50 mg/day tapering to 5-15 mg/day)."	2.75	Zonisamide versus diazepam in the treatment of alcohol withdrawal syndrome. ( Alamo, C; Ferre, F; Jiménez-Arriero, MÁ; López-Muñoz, F; Martínez-Gras, I; Pascual, JM; Ponce, G; Rubio, G, 2010)
"Levetiracetam was administered in a fixed dose schedule over 6 days."	2.75	Levetiracetam for the treatment of alcohol withdrawal syndrome: a multicenter, prospective, randomized, placebo-controlled trial. ( Heinz, A; Hinzpeter, A; Kienast, T; Plenge, T; Preuss, UW; Richter, C; Schaefer, M; Schmidt, F, 2010)
"During a 15-month period, trauma patients admitted to the ICU with a history of chronic daily alcohol consumption greater than or equal to five beverage equivalents per day were prospectively randomized to one of two 4-day prophylactic regimens: intravenous ethanol infusion (EtOH) versus scheduled-dose diazepam (BENZO)."	2.73	Comparison of intravenous ethanol versus diazepam for alcohol withdrawal prophylaxis in the trauma ICU: results of a randomized trial. ( Croce, MA; Edwards, NM; Fabian, TC; Fischer, PE; Magnotti, LJ; Schroeppel, T; Weinberg, JA, 2008)
"Cyamemazine is an original phenothiazine derivative which showed similar efficacy and tolerability to lorazepam during ethanol withdrawal in mice."	2.71	Double-blind study of cyamemazine and diazepam in the alcohol withdrawal syndrome. ( Allain, H; Aubin, HJ; Dib, M; Favre, JD; Frija-Orvoen, E; Garcia-Acosta, S; Gillet, C; Kermadi, I; Lejoyeux, M; Payen, A; Weber, M, 2005)
"Twelve male problem drinkers (Alcohol Dependence Scale; ADS score > or =9) received oral diazepam (5 mg) and placebo, in a counterbalanced manner on separate sessions."	2.71	Low-dose diazepam primes motivation for alcohol and alcohol-related semantic networks in problem drinkers. ( Poulos, CX; Zack, M, 2004)
"The drug also decreased alcohol addiction, had vegetostabilising and sedative effects."	2.68	[The efficacy and mechanisms of action of lerivon in alcoholism]. ( Anokhina, IP; Chirko, VV; Ivanets, NN; Kogan, BM; Nebarakova, TP; Rusinov, AV, 1996)
"Diazepam was more effective than clonidine and placebo on some measures of withdrawal."	2.67	Double-blind study of alprazolam, diazepam, clonidine, and placebo in the alcohol withdrawal syndrome: preliminary findings. ( Adinoff, B, 1994)
"Diazepam or lorazepam treatment is best initiated early in the course of alcohol withdrawal to prevent progression to more severe withdrawal."	2.66	[Assessment and Treatment of Alcohol Withdrawal Syndrome]. ( Choi, HY; Lee, SK; Seo, JS, 2020)
" Clinicians should consider giving patients with a tendency to abuse drugs nonidentifiable dosage forms."	2.65	Effect of patient recognition of tranquilizers on their use in alcohol detoxification. ( Francis, DA; Nelson, AA, 1984)
"Alprazolam was as effective as diazepam in the relief of anxiety as measured by the Hamilton Anxiety Rating Scale, Physician's Global Impressions, Patient's Global Impressions, Hopkins Symptom Checklist and Target Symptoms Record."	2.65	Double-blind comparison of alprazolam and diazepam for subchronic withdrawal from alcohol. ( Kolin, IS; Linet, OI, 1981)
" 2 Clobazam dosage ranged from 5 mg daily (paediatric patients) to 120 mg daily (psychiatric in-patients)."	2.65	Review of clinical studies on clobazam. ( Koeppen, D, 1979)
"Diazepam-treated patients became calm in one half the time needed to calm patients with paraldehyde."	2.64	Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial. ( Johnson, AD; Maddrey, WL; Thompson, WL, 1975)
" Uncontrolled long-term administration is to be rejected in all circumstances, and supply should be strictly on prescription only in order to prevent uncontrolled acquisition."	2.64	The use of tranquilizers in the treatment of mixed drug abuse. ( Demel, I; Kryspin-Exner, K, 1975)
"A similar problem exists with diazepam."	2.38	Alprazolam and benzodiazepine dependence. ( Ciraulo, DA; DuPont, RL; Griffiths, RR; Kosten, TR; Romach, MK; Sellers, EM; Woody, GE, 1993)
"The study was conducted on 100 Russian male patients suffering from the AWS who received diazepam injections at a dosage of 30."	1.72	Effects of CYP2C19*17 genetic polymorphisms on plasma and saliva concentrations of diazepam in patients with alcohol withdrawal syndrome. ( Bryun, E; Galaktionova, T; Grishina, E; Ryzhikova, K; Shipitsyn, V; Skryabin, VY; Sychev, D; Torrado, M; Zastrozhin, M, 2022)
"The study was conducted on 30 Russian male patients suffering from the AWS who received diazepam in injections at a dosage of 30."	1.72	Using the CYP3A Activity Evaluation to Predict the Efficacy and Safety of Diazepam in Patients With Alcohol Withdrawal Syndrome. ( Bryun, EA; Galaktionova, TE; Grishina, EA; Ivanov, AV; Ryzhikova, KA; Shipitsyn, VV; Skryabin, VY; Sorokin, AS; Sychev, DA; V Barna, I; Zastrozhin, MS, 2022)
"Benzodiazepines are the gold standard for alcohol withdrawal treatment but choice and dosing vary widely."	1.72	Outcomes of Minnesota Detoxification Scale (MINDS) Assessment With High-Dose Front Loading Diazepam Treatment for Alcohol Withdrawal in Hospitalized Patients. ( Agboto, V; Beddow, D; Hanovich, S; Holaday, K; Kirven, J; Patel, L; Smith, CS; St Hill, CA, 2022)
"The few in-ED seizures occurred before medication administration."	1.56	Lorazepam Versus Diazepam in the Management of Emergency Department Patients With Alcohol Withdrawal. ( Barbic, D; Chiu, I; Duley, S; Grafstein, E; Grunau, B; Innes, G; Kestler, A; Lane, DJ; Miles, I; Moe, J; Nolan, S; Scheuermeyer, FX; Slaunwhite, A; Sljivic, I; Ti, L; Yan, A, 2020)
"Baclofen is recommended for spasticity treatment, but it has recently been used for alcohol withdrawal symptoms reduction and alcohol abstinence."	1.48	Delirium tremens in an AUD patient after an intrathecal baclofen pump induced total alcohol abstinence. ( Calvo, ME; Gunnarsson, T; Hao, M; Smith, L, 2018)
"The high nagalase concentrations in alcohol abuse might be associated with macrophage impairment through decreasing the endogenous macrophage-activating factor (MAF) production by Gc-protein."	1.46	Alteration of α-N-acetylgalactosaminidase (nagalase) concentration in alcohol-dependent individuals without liver disease, during the detoxification therapy. ( Chatzipanagiotou, S; Ioannidis, A; Lambrokostopoulos, KT; Magana, M; Nikou, T; Paparrigopoulos, T; Tzavellas, E; Vasdekis, VG; Zoga, M, 2017)
" Medication dosage was initially higher using the HAES, so that the time needed to monitor withdrawal symptoms could be reduced (3."	1.43	[Comparison of Two Symptom-Triggered Treatments for Alcohol Withdrawal: HAES vs. SAB-P]. ( Holzbach, R; Ihlow, C; Kemper, U; Naber, D; Takla, T, 2016)
"A 69-year-old man with alcohol dependence and mild cognitive impairment (MCI) suffered from repeated tonic-clonic seizures."	1.39	Repeated seizures in an elderly patient with alcohol dependence and mild cognitive impairment. ( Araki, Y; Hatano, K; Ishii, N; Terao, T, 2013)
"We wanted to compare the intensity of withdrawal symptoms in patients hospitalised for alcohol detoxification between smokers and non-smokers."	1.37	Intensity of symptoms from alcohol withdrawal in alcohol-dependent patients: comparison between smokers and non-smokers. ( Jacques, D; Janne, P; Reynaert, C; Timary, P; Zdanowicz, N, 2011)
"In the treatment of withdrawal symptoms diazepam was used."	1.32	[Chronic ethanol abuse related hospitalisation in the Internal Medicine Department of the Specialist Hospital in Biała Podlaska (Poland)]. ( Chwaluk, P, 2004)
"Diazepam treated rats showed a higher ethanol intake and spontaneous signs of ethanol withdrawal when the access to ethanol was discontinued."	1.31	Chronic benzodiazepine administration facilitates the subsequent development of ethanol dependence. ( Bustos, SG; Lacerra, C; Martijena, ID; Molina, VA, 2001)
"These results suggest that, among alcohol abusers, cocaine is a complement to alcohol, but alcohol is a substitute for cocaine."	1.31	A behavioral economic analysis of polydrug abuse in alcoholics: asymmetrical substitution of alcohol and cocaine. ( Petry, NM, 2001)
"Temazepam was detected in 28 urine samples."	1.30	Benzodiazepine misuse by drug addicts. ( Garretty, DJ; Hay, AW; Raistrick, D; Wolff, K, 1997)
"There was a family history of alcohol dependence in (44%)."	1.30	A 3 year case study of alcohol related psychotic disorders at Hospital Seremban. ( Chin, CN; George, S, 1998)
" Drug was most often given on a fixed dosing schedule with additional medication "as needed" (52% of the programs)."	1.29	Alcohol withdrawal: a nationwide survey of inpatient treatment practices. ( Friedman, LS; Mayo-Smith, MF; Saitz, R, 1995)
"Whereas cases with concomitant Wernicke encephalopathy may also have had greater numbers of superior frontal [3H]muscimol binding sites than controls, alcoholics with cirrhosis of the liver showed more muted differences."	1.29	GABAA receptors in damaged cerebral cortex areas in human chronic alcoholics. ( Dodd, PR, 1994)
" We report five cases of high-dose triazolam abuse in which the daily dosage ranged from 5 to 15 mg (100-300 mg diazepam equivalent) and the duration of use ranged from 3 months to 5 years."	1.28	Detoxification for triazolam physical dependence. ( Sellers, EM; Sullivan, JT, 1992)
"Clonidine was found to be remarkably effective in alleviating various alcohol abstinence signs in a chronic alcoholic."	1.27	Clonidine in alcohol withdrawal: a clinical report. ( Kulkarni, GK; Kulkarni, SK; Parale, MP, 1987)
" These findings and other results of pharmacokinetic research have clinical implications in terms of dosage schedules, drug accumulation during long-term therapy, antianxiety therapy in the elderly, drug interactions, pharmacotherapy in specific disease states, and the influence of route of administration on drug action."	1.26	Clinical implications of benzodiazepine pharmacokinetics. ( Greenblatt, DJ; Shader, RI, 1977)
"Oxazepam has no important active metabolites and its net disposition is minimally altered by disulfiram."	1.26	Interaction of disulfiram with benzodiazepines. ( Billings, BJ; Giles, HG; Greenblatt, DJ; MacLeod, SM; Marshman, JA; Martin, PR; Sellers, EM, 1978)
" Diazepam (Valium) dosage (5 milligrams per kilogram of body weight) during the period ow withdrawal serves to maintain undiminished such alcohol self-administration."	1.26	Diazepam maintenance of alcohol preference during alcohol withdrawal. ( Deutsch, JA; Walton, NY, 1977)
" Despite the profound prolongation of t 1/2 (theta) with age, the constancy of diazepam clearance indicates that drug plasma concentrations will not accumulate any more in the old than the young, and chronic dosage more in the old than the young, and chronic dosage modifications based on pharmacokinetic considerations are unnecessary."	1.25	The effects of age and liver disease on the disposition and elimination of diazepam in adult man. ( Avant, GR; Hoyumpa, A; Klotz, U; Schenker, S; Wilkinson, GR, 1975)

Timeframe	Studies, this research(%)	All Research%
pre-1990	131 (56.71)	18.7374
1990's	43 (18.61)	18.2507
2000's	23 (9.96)	29.6817
2010's	23 (9.96)	24.3611
2020's	11 (4.76)	2.80

Trial	Phase	Enrollment	Study Type	Start Date	Status
Treatment Of Alcohol Withdrawal Syndrome: Dexmedetomidine Vs Diazepam In A Hospital O'horán[NCT03877120]	Phase 4	2 participants (Actual)	Interventional	2017-11-01	Completed
Efficacy and Safety of Levetiracetam in the Inpatient Treatment of Alcohol Withdrawal Syndrome [Sicherheit Und Wirksamkeit Von Levetiracetam (Keppra) für Die Behandlung Des stationären Alkoholentzugsyndroms][NCT00146471]	Phase 3	120 participants (Actual)	Interventional	2006-01-31	Completed
Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care[NCT01621711]		504 participants (Actual)	Interventional	2011-03-31	Active, not recruiting
Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464]	Phase 4	142 participants (Anticipated)	Interventional	2020-07-06	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Comparative efficacy and safety of pharmacotherapies for alcohol withdrawal: a systematic review and network meta-analysis. Addiction (Abingdon, England), 2022, Volume: 117, Issue:10 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Carbamazepine; Diazepam; Female; Hu	2022
[Assessment and Treatment of Alcohol Withdrawal Syndrome]. The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2020, 08-25, Volume: 76, Issue:2 Topics: Alcoholism; Benzodiazepines; Diazepam; Humans; Hypnotics and Sedatives; Psychotherapy; Severity of I	2020
[Abuse of alcohol and benzodiazepine during substitution therapy in heroin addicts: a review of the literature]. L'Encephale, 2009, Volume: 35, Issue:3 Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Buprenorphine; Clonazepam; Clorazepate Dipotassium;	2009
[Physiopathology of alcoholism and present status of the therapy in Japan--result of the questionnaires sent to all psychiatric care facilities]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 2007, Volume: 109, Issue:6 Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Utilization; Hospitals, Psychi	2007
Drug therapy. Current status of benzodiazepines. The New England journal of medicine, 1983, Aug-18, Volume: 309, Issue:7 Topics: Alcoholic Beverages; Alcoholism; Anesthetics; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bone Di	1983
Drug abuse in pregnancy: fetal ad neonatal effects. Drug therapeutics, 1982 Topics: Alcoholism; Birth Weight; Chlorpromazine; Diazepam; Female; Fetus; Humans; Infant, Newborn; Infant,	1982
Alprazolam and benzodiazepine dependence. The Journal of clinical psychiatry, 1993, Volume: 54 Suppl Topics: Adult; Alcoholism; Alprazolam; Benzodiazepines; Comorbidity; Diazepam; Female; Humans; Incidence; Ma	1993
Withdrawal strategies for outpatients. Alcohol, benzodiazepine, barbiturate, and opiate addictions. Canadian family physician Medecin de famille canadien, 1996, Volume: 42 Topics: Affect; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Defense Mechanisms; Diazepam; Humans; Hypn	1996
[Behavior therapy of patients with alcoholism]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl Topics: Alcohol Deterrents; Alcoholism; Anti-Anxiety Agents; Behavior Therapy; Cyanamide; Diazepam; Humans;	1997
The management of alcohol withdrawal. The Medical journal of Australia, 1986, Jul-07, Volume: 145, Issue:1 Topics: Alcoholism; Benzodiazepines; Chlormethiazole; Diazepam; Ethanol; Humans; Nursing Care; Reality Thera	1986
The role of essential fatty acids in alcohol dependence and tissue damage. Alcoholism, clinical and experimental research, 1987, Volume: 11, Issue:1 Topics: Adult; Age Factors; Alcoholism; Brain; Clinical Trials as Topic; Cognition; Diazepam; Double-Blind M	1987
Drug therapy. Benzodiazepines (second of two parts). The New England journal of medicine, 1974, Dec-05, Volume: 291, Issue:23 Topics: Affective Symptoms; Alcoholism; Analgesia; Anesthesia, General; Anesthesia, Obstetrical; Anti-Anxiet	1974
Use of beta-adrenergic receptor blocking drugs in psychiatry. Drugs, 1974, Volume: 8, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Anxiety; Chlordiazepoxide; Di	1974
The benzodiazepines. Texas medicine, 1973, Volume: 69, Issue:6 Topics: Alcoholism; Anesthesia; Animals; Antidepressive Agents; Benzazepines; Diazepam; Epilepsy; Heart Dise	1973
[Dipotassium chlorazepate. Clinical reports on a new anxiolytic]. Arzneimittel-Forschung, 1970, Volume: 20, Issue:1 Topics: Adult; Aged; Alcoholism; Automobile Driving; Cardiovascular Diseases; Diabetes Mellitus; Diazepam; D	1970
Pharmacology of benzodiazepines: laboratory and clinical correlations. Advances in pharmacology, 1967, Volume: 5 Topics: Aggression; Alcoholism; Animals; Anticonvulsants; Anxiety; Autonomic Nervous System; Avoidance Learn	1967

Article	Year
A Placebo-Controlled Randomized Trial of Vigabatrin in the Management of Acute Alcohol Withdrawal. Alcohol and alcoholism (Oxford, Oxfordshire), 2023, Jan-09, Volume: 58, Issue:1 Topics: Alcoholism; Benzodiazepines; Diazepam; Double-Blind Method; Humans; Substance Withdrawal Syndrome; V	2023
Baclofen during alcohol detoxification reduces the need for additional diazepam: a randomized placebo-controlled trial. Alcohol and alcoholism (Oxford, Oxfordshire), 2023, Sep-09, Volume: 58, Issue:5 Topics: Alcoholism; Baclofen; Benzodiazepines; Diazepam; Double-Blind Method; Humans; Single-Blind Method; S	2023
The hemodynamic effects of diazepam versus dexmedetomidine in the treatment of alcohol withdrawal syndrome: A randomized clinical trial. Medicina clinica, 2021, 12-24, Volume: 157, Issue:12 Topics: Alcoholism; Dexmedetomidine; Diazepam; Hemodynamics; Humans; Hypnotics and Sedatives; Intensive Care	2021
Thirty- Versus Ten-Day Diazepam Treatment for Alcohol Detoxification and a Comparison of Drinking Patterns, Craving, and Anxiety for up to 12 Weeks: A "Proof-of-Concept" Open-Label Randomized Controlled Trial. Journal of clinical psychopharmacology, 2017, Volume: 37, Issue:6 Topics: Adult; Alcohol Abstinence; Alcoholism; Anxiety; Craving; Diazepam; Drug Administration Schedule; Fem	2017
Predictors of resistant alcohol withdrawal (RAW): A retrospective case-control study. Drug and alcohol dependence, 2018, 11-01, Volume: 192 Topics: Adult; Aged; Alcoholism; Benzodiazepines; Case-Control Studies; Cohort Studies; Diazepam; Drug Resis	2018
Role of CYP2C19 gene polymorphism in acute alcohol withdrawal treatment with loading dose of diazepam in a South Indian population. European journal of clinical pharmacology, 2016, Volume: 72, Issue:7 Topics: Adult; Alcoholism; Cytochrome P-450 CYP2C19; Diazepam; Humans; Male; Middle Aged; Polymorphism, Gene	2016
Zonisamide versus diazepam in the treatment of alcohol withdrawal syndrome. Pharmacopsychiatry, 2010, Volume: 43, Issue:7 Topics: Adult; Alcoholism; Anticonvulsants; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; Hum	2010
Levetiracetam for the treatment of alcohol withdrawal syndrome: a multicenter, prospective, randomized, placebo-controlled trial. Journal of clinical psychopharmacology, 2010, Volume: 30, Issue:6 Topics: Adult; Alcoholism; Anticonvulsants; Diazepam; Double-Blind Method; Female; Humans; Levetiracetam; Ma	2010
Intrathecal and oral clonidine as prophylaxis for postoperative alcohol withdrawal syndrome: a randomized double-blinded study. Anesthesia and analgesia, 2004, Volume: 98, Issue:3 Topics: Administration, Oral; Adrenergic alpha-Agonists; Aged; Alcoholism; Anesthesia; Central Nervous Syste	2004
Low-dose diazepam primes motivation for alcohol and alcohol-related semantic networks in problem drinkers. Behavioural pharmacology, 2004, Volume: 15, Issue:7 Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Diazepam; Double-Blind Method; GABA Modul	2004
Predictors of benzodiazepine discontinuation in subjects manifesting complicated dependence. Substance use & misuse, 2005, Volume: 40, Issue:4 Topics: Adult; Alcoholism; Anticonvulsants; Benzodiazepines; Diagnostic and Statistical Manual of Mental Dis	2005
Double-blind study of cyamemazine and diazepam in the alcohol withdrawal syndrome. Human psychopharmacology, 2005, Volume: 20, Issue:7 Topics: Alcohol Withdrawal Delirium; Alcoholism; Antipsychotic Agents; Blood Pressure; Diazepam; Double-Blin	2005
Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam. Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:4 Topics: Adult; Alcoholism; Arousal; Autonomic Nervous System; Depression; Diazepam; Excitatory Amino Acid An	2007
Gamma-hydroxybutyrate reduces both withdrawal syndrome and hypercortisolism in severe abstinent alcoholics: an open study vs. diazepam. The American journal of drug and alcohol abuse, 2007, Volume: 33, Issue:3 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Female; Follow-Up Studies; Humans; Hydroco	2007
Comparison of intravenous ethanol versus diazepam for alcohol withdrawal prophylaxis in the trauma ICU: results of a randomized trial. The Journal of trauma, 2008, Volume: 64, Issue:1 Topics: Adult; Alcoholism; Central Nervous System Depressants; Diazepam; Emergency Service, Hospital; Ethano	2008
Effect of patient recognition of tranquilizers on their use in alcohol detoxification. American journal of hospital pharmacy, 1984, Volume: 41, Issue:3 Topics: Adult; Aged; Alcoholism; Anti-Anxiety Agents; Anxiety; Diazepam; Humans; Hydroxyzine; Male; Middle A	1984
Changes in EEG, blood levels, mood scales and performance scores during long term treatment with diazepam, phenobarbital or placebo in patients. Progress in neuro-psychopharmacology & biological psychiatry, 1982, Volume: 6, Issue:3 Topics: Adult; Alcoholism; Arousal; Diazepam; Electroencephalography; Emotions; Humans; Middle Aged; Phenoba	1982
Double-blind comparison of alprazolam and diazepam for subchronic withdrawal from alcohol. The Journal of clinical psychiatry, 1981, Volume: 42, Issue:4 Topics: Adolescent; Adult; Aged; Alcoholism; Alprazolam; Anxiety Disorders; Benzodiazepines; Clinical Trials	1981
The utility of diazepam loading in the treatment of alcohol withdrawal among psychiatric inpatients. Psychopharmacology bulletin, 1995, Volume: 31, Issue:2 Topics: Adolescent; Adult; Aged; Alcoholism; Animals; Cats; Diazepam; Female; Follow-Up Studies; Humans; Inp	1995
Double-blind study of alprazolam, diazepam, clonidine, and placebo in the alcohol withdrawal syndrome: preliminary findings. Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:4 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Alprazolam; Blood Pressure; Clonidine; Diazepam; Dou	1994
[The use of baclofen for treating affective disorders in alcoholism]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:1 Topics: Adult; Alcoholism; Amitriptyline; Baclofen; Diazepam; Drug Evaluation; Humans; Ligands; Mood Disorde	1994
Eye movement effects of diazepam in sons of alcoholic fathers and male control subjects. Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:2 Topics: Adult; Alcoholism; Arousal; Diazepam; Dose-Response Relationship, Drug; Humans; Infusions, Intraveno	1994
Propranolol versus diazepam in the management of the alcohol withdrawal syndrome: double-blind controlled trial. The American journal of drug and alcohol abuse, 1994, Volume: 20, Issue:1 Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Double-Blind Method; Humans; Male; M	1994
Baclofen administration for the treatment of affective disorders in alcoholic patients. Drug and alcohol dependence, 1993, Volume: 33, Issue:2 Topics: Administration, Oral; Adult; Alcoholism; Amitriptyline; Anxiety Disorders; Baclofen; Blood Platelets	1993
Effect of diazepam on plasma gamma-aminobutyric acid in sons of alcoholic fathers. Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:2 Topics: Adolescent; Adult; Alcoholism; Arousal; Child of Impaired Parents; Defense Mechanisms; Diazepam; GAB	1996
[Effect of pharmacotherapy of affective disorders on the psycho-semantics of alcoholic patients]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1995, Volume: 95, Issue:6 Topics: Alcoholism; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Baclofen; Color Pe	1995
[The efficacy and mechanisms of action of lerivon in alcoholism]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1996, Volume: 96, Issue:5 Topics: Adolescent; Adult; Alcohol Deterrents; Alcoholism; Amitriptyline; Anti-Anxiety Agents; Antidepressiv	1996
Alterations in pharmacodynamics of anxiolytics in abstinent alcoholic men: subjective responses, abuse liability, and electroencephalographic effects of alprazolam, diazepam, and buspirone. Journal of clinical pharmacology, 1997, Volume: 37, Issue:1 Topics: Adult; Affect; Alcoholism; Alprazolam; Anti-Anxiety Agents; Buspirone; Diazepam; Electrocardiography	1997
A double-blind comparison of abecarnil and diazepam in the treatment of uncomplicated alcohol withdrawal. Psychopharmacology, 1997, Volume: 131, Issue:2 Topics: Adult; Alcoholism; Anti-Anxiety Agents; Carbolines; Diazepam; Double-Blind Method; Humans; Male; Mid	1997
The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders. Journal of studies on alcohol, 2000, Volume: 61, Issue:6 Topics: Adaptation, Psychological; Adolescent; Adult; Alcohol Drinking; Alcoholism; Arousal; Child of Impair	2000
Clorazepate dipotassium (Tranxene): a controlled evaluation in alcoholic patients after withdrawal. Current therapeutic research, clinical and experimental, 1976, Volume: 19, Issue:5 Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Clorazepate Dipotassium;	1976
The relationship of diazepam and ketazolam blood levels to anxiety and hostility in chronic alcoholics [proceedings]. Psychopharmacology bulletin, 1978, Volume: 14, Issue:3 Topics: Adolescent; Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clinical Trials as Top	1978
Review of clinical studies on clobazam. British journal of clinical pharmacology, 1979, Volume: 7 Suppl 1 Topics: Adult; Alcoholism; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Child; Clinical Trials as Topic;	1979
A comparison of the effects of propranolol and diazepam in alcoholics. The British journal of addiction to alcohol and other drugs, 1976, Volume: 71, Issue:4 Topics: Adult; Alcoholism; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Humans; Male;	1976
Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial. Annals of internal medicine, 1975, Volume: 82, Issue:2 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Clinical Trials as Topic; Diazepam; Female; Hepatiti	1975
The use of tranquilizers in the treatment of mixed drug abuse. International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2 Topics: Adult; Alcoholism; Analgesics; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; F	1975
Response to diazepam in sons of alcoholics. Alcoholism, clinical and experimental research, 1992, Volume: 16, Issue:6 Topics: Adolescent; Adult; Alcoholism; Arousal; Diazepam; Dose-Response Relationship, Drug; Humans; Infusion	1992
Subjective feelings and changes in body sway following diazepam in sons of alcoholics and control subjects. Journal of studies on alcohol, 1991, Volume: 52, Issue:6 Topics: Adult; Alcohol Drinking; Alcoholism; Child of Impaired Parents; Diazepam; Dose-Response Relationship	1991
Response of three hormones to diazepam challenge in sons of alcoholics and controls. Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:3 Topics: Adult; Alcohol Drinking; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Growth Hormone; Hum	1991
Diazepam preference in males with and without an alcoholic first-degree relative. Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:4 Topics: Adult; Affect; Alcoholism; Analysis of Variance; Diazepam; Humans; Male; Sleep; Substance-Related Di	1991
Treatment- and task-induced changes in interhemispheric EEG. The International journal of neuroscience, 1989, Volume: 47, Issue:1-2 Topics: Alcoholism; Brain; Diazepam; Electroencephalography; Functional Laterality; Humans; Male; Phenobarbi	1989
A comparison of assessment techniques measuring the effects of methylphenidate, secobarbital, diazepam and diphenhydramine in abstinent alcoholics. Neuropsychobiology, 1988, Volume: 19, Issue:2 Topics: Adult; Alcoholism; Arousal; Attention; Diazepam; Diphenhydramine; Discrimination Learning; Humans; M	1988
The role of essential fatty acids in alcohol dependence and tissue damage. Alcoholism, clinical and experimental research, 1987, Volume: 11, Issue:1 Topics: Adult; Age Factors; Alcoholism; Brain; Clinical Trials as Topic; Cognition; Diazepam; Double-Blind M	1987
Investigation of the abuse liability of buspirone in alcohol-dependent patients. The American journal of medicine, 1986, Mar-31, Volume: 80, Issue:3B Topics: Administration, Oral; Adult; Alcoholism; Appetite; Buspirone; Diazepam; Euphoria; Humans; Male; Midd	1986
A double-blind crossover comparison between clothiapine and diazepam in the treatment of mental symptoms in chronic alcoholics. International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:4 Topics: Adult; Alcoholism; Analysis of Variance; Chronic Disease; Clinical Trials as Topic; Diazepam; Dibenz	1974
Treatment of hospitalized alcoholics with doxepin and diazepam. A controlled study. Quarterly journal of studies on alcohol, 1971, Volume: 32, Issue:1 Topics: Adult; Alcoholism; Anxiety; Clinical Trials as Topic; Depression; Diazepam; Dibenzoxepins; Humans; M	1971
The psychological effects of propranolol in the abstinence phase of chronic alcoholics. The British journal of psychiatry : the journal of mental science, 1971, Volume: 119, Issue:553 Topics: Adult; Alcoholism; Anxiety; Chlormethiazole; Chronic Disease; Clinical Trials as Topic; Diazepam; Hu	1971

Article	Year
Outcomes of Minnesota Detoxification Scale (MINDS) Assessment With High-Dose Front Loading Diazepam Treatment for Alcohol Withdrawal in Hospitalized Patients. The American journal of the medical sciences, 2022, Volume: 363, Issue:1 Topics: Alcoholism; Benzodiazepines; Diazepam; Ethanol; Humans; Minnesota; Retrospective Studies; Substance	2022
Effects of CYP2C1917 genetic polymorphisms on plasma and saliva concentrations of diazepam in patients with alcohol withdrawal syndrome. Psychiatric genetics, 2022, 04-01, Volume: 32, Issue:2* Topics: Alcoholism; Cytochrome P-450 CYP2C19; Diazepam; Humans; Male; Polymorphism, Genetic; Saliva; Substan	2022
Nordic journal of psychiatry, 2023, Volume: 77, Issue:1 Topics: Alcoholism; Cytochrome P-450 CYP3A; Diazepam; Genotype; Humans; Male; Polymorphism, Genetic; Substan	2023
Inhibitory and excitatory synaptic neuroadaptations in the diazepam tolerant brain. Neurobiology of disease, 2023, Volume: 185 Topics: Alcoholism; Animals; Benzodiazepines; Brain; Diazepam; gamma-Aminobutyric Acid; Mice; Receptors, GAB	2023
Lorazepam Versus Diazepam in the Management of Emergency Department Patients With Alcohol Withdrawal. Annals of emergency medicine, 2020, Volume: 76, Issue:6 Topics: Adult; Alcoholism; Benzodiazepines; Canada; Diazepam; Emergency Service, Hospital; Female; Hospitali	2020
Using the CYP3A Activity Evaluation to Predict the Efficacy and Safety of Diazepam in Patients With Alcohol Withdrawal Syndrome. Journal of pharmacy practice, 2022, Volume: 35, Issue:4 Topics: Alcoholism; Cytochrome P-450 CYP3A; Diazepam; Humans; Hydrocortisone; Hypnotics and Sedatives; Male;	2022
Comparison of Clomethiazole and Diazepam in the Treatment of Alcohol Withdrawal Syndrome in Clinical Practice. European addiction research, 2017, Volume: 23, Issue:4 Topics: Alcoholism; Chlormethiazole; Diazepam; Female; Germany; Humans; Male; Middle Aged; Retrospective Stu	2017
DNA damage and oxidative stress induced by seizures are decreased by anticonvulsant and neuroprotective effects of lobeline, a candidate to treat alcoholism. Metabolic brain disease, 2018, Volume: 33, Issue:1 Topics: Alcoholism; Animals; Anticonvulsants; Antioxidants; Diazepam; Disease Models, Animal; DNA Damage; Hi	2018
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high-dosage baclofen. Fundamental & clinical pharmacology, 2018, Volume: 32, Issue:2 Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Baclofen; Diazepam; Female; GABA Modulato	2018
"Diazepam loading": ¿Can a strategy for preventing alcohol withdrawal be used to treat benzodiazepine use disorder? Adicciones, 2018, Apr-15, Volume: 30, Issue:2 Topics: Alcoholism; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Female; Humans; Middle Aged; Substance W	2018
Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model. European journal of drug metabolism and pharmacokinetics, 2018, Volume: 43, Issue:4 Topics: Acid-Base Equilibrium; Acidosis; Alcoholism; Benzodiazepines; Diazepam; Female; Humans; Injections,	2018
Minocycline in Alcohol Withdrawal Induced Anxiety and Alcohol Relapse in Rats. Current clinical pharmacology, 2018, Volume: 13, Issue:1 Topics: Alcohol Drinking; Alcoholism; Animals; Anti-Bacterial Agents; Anxiety; Diazepam; Disease Models, Ani	2018
Repeated diazepam administration reversed working memory impairments and glucocorticoid alterations in the prefrontal cortex after short but not long alcohol-withdrawal periods. Cognitive, affective & behavioral neuroscience, 2018, Volume: 18, Issue:4 Topics: Alcoholism; Animals; Anxiety; Central Nervous System Depressants; Cyclic AMP Response Element-Bindin	2018
Considerations for the use of a loading dose of diazepam for the treatment of benzodiazepine dependence. Adicciones, 2018, 07-12, Volume: 30, Issue:3 Topics: Alcoholism; Benzodiazepines; Diazepam; Humans; Substance Withdrawal Syndrome; Substance-Related Diso	2018
Delirium tremens in an AUD patient after an intrathecal baclofen pump induced total alcohol abstinence. European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:16 Topics: Alcohol Abstinence; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Baclofen; Diazepam; H	2018
Effect of early and focused benzodiazepine therapy on length of stay in severe alcohol withdrawal syndrome. Clinical toxicology (Philadelphia, Pa.), 2019, Volume: 57, Issue:7 Topics: Academic Medical Centers; Adult; Alcoholism; Benzodiazepines; Cohort Studies; Diazepam; Female; Huma	2019
The associations between self-consciousness, depressive state and craving to drink among alcohol dependent patients undergoing protracted withdrawal. PloS one, 2013, Volume: 8, Issue:8 Topics: Adult; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Depression; Diazepam; Female; Humans; Male	2013
Repeated seizures in an elderly patient with alcohol dependence and mild cognitive impairment. BMJ case reports, 2013, Nov-22, Volume: 2013 Topics: Aged; Alcohol Withdrawal Seizures; Alcoholism; Cognitive Dysfunction; Diazepam; Humans; Male; Valpro	2013
A heuristic model of alcohol dependence. PloS one, 2014, Volume: 9, Issue:3 Topics: Alcoholism; Diazepam; gamma-Aminobutyric Acid; Glutamic Acid; Humans; Models, Biological; Models, Ps	2014
Attenuation of alcohol withdrawal syndrome and blood cortisol level with forced exercise in comparison with diazepam. Acta medica Iranica, 2015, Volume: 53, Issue:5 Topics: Alcohol-Induced Disorders; Alcoholism; Animals; Diazepam; Ethanol; Hydrocortisone; Male; Mice; Physi	2015
[Comparison of Two Symptom-Triggered Treatments for Alcohol Withdrawal: HAES vs. SAB-P]. Fortschritte der Neurologie-Psychiatrie, 2016, Volume: 84, Issue:2 Topics: Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Central Nervous System Depressants; Chlormethi	2016
A case of methemoglobinemia after ingestion of a chlorhexidine in alcohol solution in an alcohol-dependent patient. Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:7 Topics: Administration, Oral; Alcoholism; Chlorhexidine; Cyanosis; Diazepam; Dose-Response Relationship, Dru	2016
Alteration of α-N-acetylgalactosaminidase (nagalase) concentration in alcohol-dependent individuals without liver disease, during the detoxification therapy. Drug and alcohol dependence, 2017, Jan-01, Volume: 170 Topics: Adult; Alcoholism; alpha-N-Acetylgalactosaminidase; Diazepam; Enzyme-Linked Immunosorbent Assay; Fem	2017
Intensity of symptoms from alcohol withdrawal in alcohol-dependent patients: comparison between smokers and non-smokers. Psychiatria Danubina, 2011, Volume: 23 Suppl 1 Topics: Adult; Alcohol-Induced Disorders; Alcoholism; Anticonvulsants; Blood Pressure; Diazepam; Dose-Respon	2011
Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Molecular pharmacology, 2003, Volume: 63, Issue:1 Topics: Affinity Labels; Alcoholism; Allosteric Regulation; Anesthetics; Animals; Anxiety; Azides; Benzodiaz	2003
Management of drug and alcohol withdrawal. The New England journal of medicine, 2003, Jul-24, Volume: 349, Issue:4 Topics: Alcoholism; Anticonvulsants; Diazepam; Half-Life; Humans; Lorazepam; Substance Withdrawal Syndrome	2003
CURRENT ADVANCES IN THE AMBULATORY MEDICAL TREATMENT OF ALCOHOLICS. Bulletin - Academy of Medicine of New Jersey, 1963, Volume: 9 Topics: Alcohol Deterrents; Alcoholics; Alcoholism; Chlordiazepoxide; Diazepam; Disulfiram; Humans; Lysergic	1963
[CLINICAL EVALUATION OF BENZODIAZEPINONE]. El Dia medico, 1963, Dec-23, Volume: 35 Topics: Alcoholism; Diazepam; Epilepsy; Humans; Mental Disorders; Tranquilizing Agents	1963
COMPARISON OF DIAZEPAM, CHLORPROTHIXENE AND CHLORPROMAZINE IN CHRONIC SCHIZOPHRENIC PATIENTS. Diseases of the nervous system, 1964, Volume: 25 Topics: Alcoholism; Brain; Brain Damage, Chronic; Chlorpromazine; Chlorprothixene; Diazepam; Schizophrenia;	1964
TRANSIENT ENURESIS FROM CHLORDIAZEPOXIDE AND DIAZEPAM. The American journal of psychiatry, 1964, Volume: 120 Topics: Alcoholism; Chlordiazepoxide; Diazepam; Enuresis; Neurotic Disorders; Toxicology; Tranquilizing Agen	1964
[TRIALS WITH RO 5-2807 IN ALCOHOLICS (98 CASES)]. Annales medico-psychologiques, 1964, Volume: 122 Topics: Alcoholic Intoxication; Alcoholics; Alcoholism; Diazepam; Humans; Mental Disorders; Psychoses, Alcoh	1964
[DIAZEPAM IN HOSPITAL PSYCHIATRIC PRACTICE]. Journal de medecine de Lyon, 1964, Oct-20, Volume: 45 Topics: Alcoholism; Diazepam; Drug Therapy; Hospitals, Psychiatric; Mental Disorders; Neurotic Disorders; Ps	1964
DIAZEPAM IN A GENERAL PSYCHIATRIC PRACTICE. The American journal of psychiatry, 1964, Volume: 121 Topics: Alcoholism; Antisocial Personality Disorder; Convulsive Therapy; Diazepam; Drug Therapy; Electroconv	1964
[TEST OF EVALUATION OF A NEW ANXIOLYTIC CALLED VALIUM]. Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1964, Volume: 9 Topics: Alcoholism; Anti-Anxiety Agents; Biomedical Research; Diazepam; Drug Therapy; Mental Disorders; Toxi	1964
DOUBLE-BLIND STUDY OF THREE DRUGS IN THE TREATMENT OF ACUTE ALCOHOLIC STATES. Quarterly journal of studies on alcohol, 1965, Volume: 26 Topics: Alcoholism; Biomedical Research; Chlordiazepoxide; Diazepam; Double-Blind Method; Drug Therapy; Prom	1965
Altered pharmacology of synaptic and extrasynaptic GABAA receptors on CA1 hippocampal neurons is consistent with subunit changes in a model of alcohol withdrawal and dependence. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:3 Topics: Alcoholism; Animals; Azides; Benzodiazepines; Diazepam; Drug Interactions; Ethanol; GABA Agonists; H	2004
CONTROLLED EVALUATION OF PSYCHOTHERAPEUTIC DRUG IN INTERNAL MEDICINE. Clinical medicine (Northfield, Ill.), 1963, Volume: 70 Topics: Alcoholism; Diazepam; Female; Geriatrics; Humans; Internal Medicine; Menopause; Neurotic Disorders;	1963
[Chronic ethanol abuse related hospitalisation in the Internal Medicine Department of the Specialist Hospital in Biała Podlaska (Poland)]. Przeglad lekarski, 2004, Volume: 61, Issue:4 Topics: Adult; Alcoholism; Anti-Anxiety Agents; Diazepam; Ethanol; Female; Humans; Liver Cirrhosis, Alcoholi	2004
Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:4 Topics: Alcoholism; Animals; Diazepam; Discrimination, Psychological; Disease Models, Animal; Drug Interacti	2005
Diazepam with your dinner, Sir? The lifestyle drug-substitution strategy: a radical alcohol policy. QJM : monthly journal of the Association of Physicians, 2005, Volume: 98, Issue:6 Topics: Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Cannabis; Diazepam; Health Policy; Humans; Life S	2005
[Symmetrical bullous acral erythema in a 58-year-old female alcoholic]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2006, Volume: 57, Issue:11 Topics: Administration, Oral; Alcoholism; Anti-Anxiety Agents; Biopsy; Depression; Diagnosis, Differential;	2006
Small human hepatocytes in rotary culture for treatment of alcohol addicts? A pilot study. Alcoholism, clinical and experimental research, 2007, Volume: 31, Issue:5 Topics: Alcoholism; Cell Count; Cell Culture Techniques; Cell Line; Culture Media; Cytochrome P-450 Enzyme S	2007
[Benzodiazepine and opiate receptor function in chronic alcoholization]. Vestnik Akademii meditsinskikh nauk SSSR, 1984, Issue:11 Topics: Alcoholism; Animals; Brain; Diazepam; Emotions; Ethanol; Humans; Naloxone; Rats; Receptors, GABA-A;	1984
Drug and alcohol problems in Kenya today: a review of research. East African medical journal, 1982, Volume: 59, Issue:10 Topics: Adult; Alcoholism; Catha; Central Nervous System Stimulants; Diazepam; Female; Humans; Kenya; Male;	1982
The benzodiazepine/GABA receptor complex during severe ethanol intoxication and withdrawal in the rat. Acta psychiatrica Scandinavica, 1982, Volume: 65, Issue:2 Topics: Alcoholic Intoxication; Alcoholism; Animals; Diazepam; Ethanol; Flunitrazepam; Humans; Male; Rats; R	1982
[Psychophysiological reactions to seduxen in patients with chronic alcoholism]. Sovetskaia meditsina, 1984, Issue:10 Topics: Adult; Alcoholism; Diazepam; Humans; Male; Middle Aged; Psychomotor Performance	1984
Students and drug abuse, 1974 and 1980. The Journal of school health, 1983, Volume: 53, Issue:7 Topics: Adolescent; Alcoholism; Aspirin; Child; Diazepam; Humans; Marijuana Abuse; Methaqualone; Students; S	1983
Dexamethasone suppression test in alcoholism. Acta psychiatrica Scandinavica, 1984, Volume: 69, Issue:2 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Depressive Disorder; Dexamethasone; Diazepam; Female	1984
Pharmacological requirements of patients during alcohol withdrawal. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Jan-24, Volume: 59, Issue:4 Topics: Alcoholism; Diazepam; Ethanol; Humans; Nordazepam	1981
Diazepam pharmacokinetics after intravenous administration in alcohol withdrawal. British journal of clinical pharmacology, 1983, Volume: 15, Issue:1 Topics: Adult; Alcoholism; Diazepam; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; S	1983
Intraoperative awareness and hypertensive crisis during high-dose fentanyl-diazepam-oxygen anesthesia. Anesthesia and analgesia, 1983, Volume: 62, Issue:7 Topics: Alcoholism; Anesthesia, Intravenous; Awareness; Cognition; Diazepam; Fentanyl; Humans; Hypertension;	1983
Alcohol withdrawal syndromes - prediction from detailed medical and drinking histories. Drug and alcohol dependence, 1983, Volume: 11, Issue:2 Topics: Adult; Aged; Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Female; Flurazepam	1983
Treating substance-use disorders among physicians. JAMA, 1982, Apr-23, Volume: 247, Issue:16 Topics: Adult; Alcoholics Anonymous; Alcoholism; Barbiturates; Diazepam; Female; Humans; Male; Middle Aged;	1982
Health care in jails: a unique challenge in medical practice. Postgraduate medicine, 1982, Volume: 72, Issue:3 Topics: Adult; Alcoholism; Cannabis; Diazepam; Ethics, Medical; Female; Health Services; Heroin; Humans; Mal	1982
A clinical appraisal of diazepam. Psychosomatics, 1981, Volume: 22, Issue:9 Topics: Administration, Oral; Aged; Alcoholism; Anxiety; Child; Diazepam; Drug Administration Schedule; Huma	1981
[The acute psychiatric emergency]. Zeitschrift fur Alternsforschung, 1981, Volume: 36, Issue:4 Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D	1981
[Plasma catecholamines in accidental hypothermia (author's transl)]. Wiener klinische Wochenschrift, 1980, Sep-26, Volume: 92, Issue:18 Topics: Adult; Alcoholism; Child, Preschool; Diazepam; Epinephrine; Humans; Hypothermia; Male; Middle Aged;	1980
Management of alcohol withdrawal. Mayo Clinic proceedings, 1995, Volume: 70, Issue:12 Topics: Adrenergic alpha-Agonists; Alcoholism; Anti-Anxiety Agents; Clonidine; Diazepam; Humans; Midazolam;	1995
Alcohol and benzodiazepines generate anxiety, panic and phobias. Journal of the Royal Society of Medicine, 1995, Volume: 88, Issue:2 Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female;	1995
Clinical observations on substance abuse related health problems at the Port Moresby General Hospital, National Capital District, Papua New Guinea. Medicine and law, 1994, Volume: 13, Issue:3-4 Topics: Adolescent; Adult; Alcoholism; Cross-Sectional Studies; Diazepam; Female; Humans; Incidence; Male; M	1994
Effects of MK 801 and diazepam on the EEG of P and NP rats. Alcoholism, clinical and experimental research, 1994, Volume: 18, Issue:2 Topics: Alcoholism; Amygdala; Animals; Diazepam; Dizocilpine Maleate; Electroencephalography; Ethanol; Front	1994
Alcohol withdrawal: a nationwide survey of inpatient treatment practices. Journal of general internal medicine, 1995, Volume: 10, Issue:9 Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine;	1995
Current treatment for alcohol withdrawal. Journal of general internal medicine, 1995, Volume: 10, Issue:9 Topics: Alcoholism; Benzodiazepines; Chlordiazepoxide; Diazepam; Humans; Substance Withdrawal Syndrome	1995
Acute encephalopathy and polyneuropathy after disulfiram intoxication. Alcohol and alcoholism (Oxford, Oxfordshire), 1995, Volume: 30, Issue:5 Topics: Adult; Alcohol Deterrents; Alcoholism; Diazepam; Disulfiram; Dose-Response Relationship, Drug; Drug	1995
Out-patient alcohol detoxification--outcome after 2 months. Alcohol and alcoholism (Oxford, Oxfordshire), 1995, Volume: 30, Issue:5 Topics: Adult; Aged; Alcoholics Anonymous; Alcoholism; Ambulatory Care; Cognitive Behavioral Therapy; Combin	1995
The neurochemical pathology of thiamine deficiency: GABAA and glutamateNMDA receptor binding sites in a goat model. Metabolic brain disease, 1996, Volume: 11, Issue:1 Topics: Alcoholism; Amprolium; Animals; Brain Chemistry; Diazepam; Disease Models, Animal; Dizocilpine Malea	1996
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepi	1996
Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy. Brain research, 1996, Feb-26, Volume: 710, Issue:1-2 Topics: Adult; Aged; Aged, 80 and over; Alcoholism; Binding Sites; Diazepam; Female; Fibrosis; Flunitrazepam	1996
GABAA receptors in damaged cerebral cortex areas in human chronic alcoholics. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1994, Volume: 2 Topics: Adult; Aged; Alcoholism; Binding Sites; Case-Control Studies; Cerebral Cortex; Diazepam; Flunitrazep	1994
Benzodiazepine misuse by drug addicts. Annals of clinical biochemistry, 1997, Volume: 34 ( Pt 1) Topics: Alcoholism; Benzodiazepines; Chromatography, High Pressure Liquid; Diazepam; Humans; Narcotics; Nitr	1997
Cyanamide-induced granulocytopenia. Internal medicine (Tokyo, Japan), 1997, Volume: 36, Issue:9 Topics: Agranulocytosis; Alcoholism; Antiemetics; Cyanamide; Dermatitis; Diazepam; Glyburide; Granulocyte Co	1997
Lower activity of serum peptidases in abstinent alcohol-dependent patients. Alcohol (Fayetteville, N.Y.), 1999, Volume: 17, Issue:1 Topics: Adult; Alcoholism; Diazepam; Dipeptidyl Peptidase 4; Female; Granulocyte-Macrophage Colony-Stimulati	1999
The alcohol withdrawal syndrome. Family & community health, 1979, Volume: 2, Issue:2 Topics: Alcoholism; Chlordiazepoxide; Diazepam; Drug Tolerance; Ethanol; Hospitalization; Humans; Substance	1979
Relationship between a GABAA alpha 6 Pro385Ser substitution and benzodiazepine sensitivity. The American journal of psychiatry, 1999, Volume: 156, Issue:9 Topics: Adolescent; Adult; Alcoholism; Amino Acid Substitution; Animals; Anti-Anxiety Agents; Benzodiazepine	1999
The treatment of sedative-hypnotic dependence: evaluating clinical predictors of outcome. The Journal of clinical psychiatry, 2000, Volume: 61, Issue:3 Topics: Adult; Alcoholism; Benzodiazepines; Clonazepam; Combined Modality Therapy; Comorbidity; Diazepam; Dr	2000
Chronic exposure to ethanol alters GABA(A) receptor-mediated responses of layer II pyramidal cells in adult rat piriform cortex. Journal of neurophysiology, 2000, Volume: 84, Issue:1 Topics: Age Factors; Alcoholism; Animals; Bicuculline; Central Nervous System Depressants; Cerebral Cortex;	2000
A 3 year case study of alcohol related psychotic disorders at Hospital Seremban. The Medical journal of Malaysia, 1998, Volume: 53, Issue:3 Topics: Adult; Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Diazepam; Drug Therapy, Combination; F	1998
Chronic benzodiazepine administration facilitates the subsequent development of ethanol dependence. Brain research, 2001, Feb-09, Volume: 891, Issue:1-2 Topics: Alcoholism; Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Dose-Response Relationship, Dru	2001
A behavioral economic analysis of polydrug abuse in alcoholics: asymmetrical substitution of alcohol and cocaine. Drug and alcohol dependence, 2001, Mar-01, Volume: 62, Issue:1 Topics: Adult; Alcoholic Beverages; Alcoholism; Analysis of Variance; Cocaine; Cocaine-Related Disorders; Di	2001
Introducing an in-patient treatment for alcohol detoxification into a community setting. Journal of clinical nursing, 2001, Volume: 10, Issue:5 Topics: Absenteeism; Alcoholism; Anti-Anxiety Agents; Clinical Protocols; Community Health Nursing; Cost of	2001
Tardive dyskinesia: relationship with a primary affective disorder. Diseases of the nervous system, 1977, Volume: 38, Issue:6 Topics: Adult; Affective Symptoms; Aged; Alcoholism; Amitriptyline; Antipsychotic Agents; Chlordiazepoxide;	1977
Clinical implications of benzodiazepine pharmacokinetics. The American journal of psychiatry, 1977, Volume: 134, Issue:6 Topics: Administration, Oral; Adult; Age Factors; Aged; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; C	1977
Recent advances in alcohol withdrawal states. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Nov-26, Volume: 52, Issue:23 Topics: Adrenergic beta-Antagonists; Adult; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hum	1977
Interaction of disulfiram with benzodiazepines. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5 Topics: Adult; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Disulfiram; Drug Interactions; H	1978
Withdrawal symptoms from combined alcohol and minor tranquilizer intake. The Journal of the Oklahoma State Medical Association, 1979, Volume: 72, Issue:10 Topics: Alcoholism; Anti-Anxiety Agents; Diazepam; Humans; Substance Withdrawal Syndrome; Time Factors	1979
Abuse of benzodiazepines. Lancet (London, England), 1978, Nov-11, Volume: 2, Issue:8098 Topics: Alcoholism; Anti-Anxiety Agents; Chlormethiazole; Diazepam; Drug Synergism; Humans; Lorazepam; Male;	1978
Benzodiazepine abuse in alcoholics. Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101 Topics: Alcoholism; Diazepam; Humans; Substance-Related Disorders	1978
[Experimental study on development of physical dependence on alcohol and cross physical dependence liability of diazepam and barbital to alcohol in rhesus monkeys (author's transl)]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1978, Dec-25, Volume: 80, Issue:12 Topics: Alcoholism; Animals; Barbital; Barbiturates; Body Weight; Diazepam; Female; Haplorhini; Humans; Maca	1978
[Experimental studies of alcoholism]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, 1979, Mar-25, Volume: 81, Issue:3 Topics: Alcoholic Intoxication; Alcoholism; Animals; Barbital; Diazepam; Dogs; Ethanol; Female; Haplorhini;	1979
Reinforcement of drug abstinence: a behavioral approach to drug abuse treatment. NIDA research monograph, 1979, Issue:25 Topics: Adult; Alcoholism; Behavior Therapy; Diazepam; Heroin Dependence; Humans; Methadone; Opioid-Related	1979
Pharmacotherapy of the acute alcohol withdrawal syndrome. Diseases of the nervous system, 1975, Volume: 36, Issue:4 Topics: Alcoholism; Anti-Anxiety Agents; Barbiturates; Chemical and Drug Induced Liver Injury; Chloral Hydra	1975
Rational drug therapy of alcoholism with sedative hypnotic drugs! Is this possible? Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252 Topics: Administration, Oral; Alcoholism; Antipsychotic Agents; Anxiety; Barbiturates; Community Mental Heal	1975
The use of psychoactive drugs in the long-term treatment of chronic alcoholics. Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252 Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch	1975
The treatment of alcoholism: what do we do about long-term sedatives? Annals of the New York Academy of Sciences, 1975, Apr-25, Volume: 252 Topics: Alcoholics Anonymous; Alcoholism; Anti-Anxiety Agents; Attitude of Health Personnel; Chlordiazepoxid	1975
Are all recently detoxified alcoholics depressed? The American journal of psychiatry, 1979, Volume: 136, Issue:4B Topics: Alcoholism; Chlordiazepoxide; Depression; Diazepam; Humans; Male; Psychological Tests	1979
Granulocytic adherence in chronic alcoholism. American journal of clinical pathology, 1979, Volume: 71, Issue:3 Topics: Adult; Alcoholism; Cell Adhesion; Diazepam; Female; Granulocytes; Humans; Hydroxyzine; Leukocyte Cou	1979
Massive benzodiazepine requirements during acute alcohol withdrawal. The American journal of psychiatry, 1979, Volume: 136, Issue:6 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Half-Lif	1979
Diazepam kinetics in acute alcohol withdrawal. Clinical pharmacology and therapeutics, 1979, Volume: 25, Issue:6 Topics: Adult; Alcoholism; Blood Proteins; Diazepam; Half-Life; Humans; Kinetics; Male; Middle Aged; Protein	1979
Ambulatory alcohol withdrawal. Currents in alcoholism, 1979, Volume: 6 Topics: Alcoholism; Ambulatory Care; Ambulatory Care Facilities; California; Diazepam; Humans; Hydroxyzine	1979
Studies of cognitive function as influenced by administration of haloperidol or diazepam in detoxification of acute alcoholics. Methods and findings in experimental and clinical pharmacology, 1979, Volume: 1, Issue:1 Topics: Adult; Alcoholism; Cognition; Diazepam; Double-Blind Method; Female; Haloperidol; Humans; Male; Perc	1979
Diazepam maintenance of alcohol preference during alcohol withdrawal. Science (New York, N.Y.), 1977, Oct-21, Volume: 198, Issue:4314 Topics: Alcohol Drinking; Alcoholism; Animals; Diazepam; Humans; Male; Rats; Substance Withdrawal Syndrome	1977
A study on diazepam and postwithdrawal drinking of ethanol solution in rats. Toxicology and applied pharmacology, 1979, Sep-15, Volume: 50, Issue:2 Topics: Alcohol Drinking; Alcoholism; Animals; Body Weight; Diazepam; Feeding Behavior; Humans; Male; Rats;	1979
Management of alcohol withdrawal syndromes. Archives of internal medicine, 1978, Volume: 138, Issue:2 Topics: Alcohol Drinking; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Dru	1978
[Treatment of drug-dependent alcoholics in a non-psychiatric medical milieu. Withdrawal treatment technic]. Bruxelles medical, 1978, Volume: 58, Issue:7 Topics: Alcoholism; Diazepam; Humans; Hypnotics and Sedatives; Nutritional Physiological Phenomena; Thiamine	1978
Recognizing and managing the outpatient alcoholic. American family physician, 1977, Volume: 15, Issue:3 Topics: Alcoholism; Ambulatory Care; Chlordiazepoxide; Diazepam; Disulfiram; Hospitalization; Humans; Physic	1977
Diazepam withdrawal psychosis: a case report. The American journal of psychiatry, 1977, Volume: 134, Issue:5 Topics: Alcoholism; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Psychotic Disorde	1977
Plasma protein binding of diazepam and tolbutamide in chronic alcoholics. Journal of clinical pharmacology, 1976, Volume: 16, Issue:7 Topics: Alcoholism; Blood Proteins; Chemical and Drug Induced Liver Injury; Chronic Disease; Diazepam; Femal	1976
A warfarin embryopathy? American journal of diseases of children (1960), 1975, Volume: 129, Issue:3 Topics: Abnormalities, Drug-Induced; Alcoholism; Chondrodysplasia Punctata; Diazepam; Digitalis Glycosides;	1975
Chondrodysplasia punctata and maternal warfarin use during pregnancy. American journal of diseases of children (1960), 1975, Volume: 129, Issue:3 Topics: Abnormalities, Drug-Induced; Alcoholism; Cerebrovascular Disorders; Chondrodysplasia Punctata; Contr	1975
The effects of age and liver disease on the disposition and elimination of diazepam in adult man. The Journal of clinical investigation, 1975, Volume: 55, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Aging; Alcoholism; Animals; Diazepam; Fe	1975
[Withdrawal psychosis developing in association with incarceration in a penal institution]. Ugeskrift for laeger, 1975, Mar-10, Volume: 137, Issue:11 Topics: Adult; Alcoholism; Diazepam; Humans; Male; Prisons; Psychotic Disorders; Substance Withdrawal Syndro	1975
[Is diazepam a narcotics?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1975, Mar-10, Volume: 95, Issue:7 Topics: Alcoholism; Diazepam; Humans	1975
Reduced concentrations of plasma diazepam in chronic alcoholic patients following an oral administration of diazepam. Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:1 Topics: Administration, Oral; Adult; Alcoholism; Chromatography, Gas; Chronic Disease; Diazepam; Female; Hum	1975
Human and animal study on elimination from plasma and metabolism of diazepam after chronic alcohol intake. Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:1 Topics: Adult; Alcoholism; Animals; Depression, Chemical; Diazepam; Ethanol; Female; Humans; Injections, Int	1975
Detoxification for triazolam physical dependence. Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:2 Topics: Adult; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Female; Half-Life; Hospitalization; H	1992
Cerebellar and frontal cortical benzodiazepine receptors in human alcoholics and chronically alcohol-drinking rats. Biological psychiatry, 1992, Apr-15, Volume: 31, Issue:8 Topics: Adult; Alcohol Drinking; Alcoholism; Animals; Azides; Benzodiazepines; Brain; Cerebellum; Diazepam;	1992
Grand mal status epilepticus. Journal of clinical pharmacology, 1992, Volume: 32, Issue:3 Topics: Alcoholism; Anticonvulsants; Diazepam; Epilepsy, Tonic-Clonic; Ethanol; Humans; Lorazepam; Male; Mid	1992
Acamprosate and diazepam differentially modulate alcohol-induced behavioural and cortical alterations in rats following chronic inhalation of ethanol vapour. Alcohol and alcoholism (Oxford, Oxfordshire), 1991, Volume: 26, Issue:2 Topics: Acamprosate; Administration, Inhalation; Alcohol Drinking; Alcoholic Intoxication; Alcoholism; Anima	1991
Diazepam preference in males with and without a family history of alcoholism. NIDA research monograph, 1990, Volume: 105 Topics: Affect; Alcoholism; Diazepam; Family; Humans; Male	1990
A structured programme for out-patient alcohol detoxification. The British journal of psychiatry : the journal of mental science, 1990, Volume: 156 Topics: Adolescent; Adult; Aged; Alcoholism; Ambulatory Care; Counseling; Diazepam; Emergency Service, Hospi	1990
The diagnosis and treatment of panic disorder in alcoholics: three cases. The American journal of drug and alcohol abuse, 1990, Volume: 16, Issue:3-4 Topics: Adult; Alcohol Drinking; Alcoholism; Anxiety Disorders; Clonazepam; Diazepam; Follow-Up Studies; Hum	1990
Subjective feelings of anxiety in young men after ethanol and diazepam infusions. The Journal of clinical psychiatry, 1990, Volume: 51, Issue:1 Topics: Adult; Affect; Alcohol Drinking; Alcoholic Beverages; Alcoholism; Anxiety; Diazepam; Dose-Response R	1990
The GABA/benzodiazepine receptor chloride channel complex during repeated episodes of physical ethanol dependence in the rat. Psychopharmacology, 1988, Volume: 96, Issue:2 Topics: Alcoholism; Animals; Chlorides; Diazepam; Ion Channels; Male; Muscimol; Radioligand Assay; Rats; Rat	1988
Diazepam loading for alcohol withdrawal: seizure risk in epileptics. Biological psychiatry, 1989, Volume: 26, Issue:8 Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relati	1989
[The pre-delirium syndrome in alcoholic patients in ambulatory care and its treatment]. Psychiatrie, Neurologie, und medizinische Psychologie, 1989, Volume: 41, Issue:2 Topics: Adolescent; Adult; Aged; Alcohol Withdrawal Delirium; Alcoholism; Chlormethiazole; Combined Modality	1989
Necropsy study of GABA/benzodiazepine receptor binding sites in brain tissue from chronic alcoholic patients. Clinical and experimental neurology, 1988, Volume: 25 Topics: Alcoholism; Brain; Diazepam; Flunitrazepam; Humans; Receptors, GABA-A	1988
[Anxiolytic action of beta-carbolines in rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 99, Issue:4 Topics: Alcoholism; Animals; Anti-Anxiety Agents; Bicuculline; Carbolines; Diazepam; Drug Evaluation, Precli	1985
[Role of benzodiazepine receptors in realizing the anxiolytic effect of compounds on intact rats and on animals with a physical dependence ethanol]. Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:2 Topics: Alcoholism; Animals; Anti-Anxiety Agents; Brain; Diazepam; Drug Evaluation, Preclinical; Rats; Recep	1986
[Effect of the combined use of benzodiazepine preparations and alcohol on fetal development in an experiment]. Akusherstvo i ginekologiia, 1988, Volume: 27, Issue:3 Topics: Alcoholism; Animals; Animals, Newborn; Anti-Anxiety Agents; Diazepam; Drug Interactions; Embryonic a	1988
[Changes in the reproductive potentials of rat progeny treated during pregnancy with alcohol, diazepam, medazepam and their combinations]. Akusherstvo i ginekologiia, 1988, Volume: 27, Issue:4 Topics: Alcoholism; Animals; Anti-Anxiety Agents; Diazepam; Drug Interactions; Ethanol; Female; Male; Medaze	1988
Major patterns of polydrug abuse among heroin addicts. NIDA research monograph, 1986, Volume: 67 Topics: Alcoholism; Amphetamines; Barbiturates; Cannabis; Cocaine; Diazepam; Heroin Dependence; Humans; Male	1986
A personal story. The Pulse of the Montana State Nurses' Association, 1988, Volume: 24, Issue:8 Topics: Alcoholism; Diazepam; Female; Humans; Nurses; Professional Impairment; Substance-Related Disorders	1988
[Positive modulation of diazepam activity by cortexolone in alcoholic rats]. Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:5 Topics: 17-Hydroxycorticosteroids; Alcoholism; Animals; Cortodoxone; Diazepam; Drug Combinations; Male; Rats	1988
Clonidine in alcohol withdrawal: a clinical report. Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:10 Topics: Adult; Alcoholism; Clonidine; Diazepam; Humans; Male; Substance Withdrawal Syndrome	1987
Acetaldehyde adducts with serum proteins are not responsible for decreased drug binding in alcoholic patients. Drug and alcohol dependence, 1986, Volume: 17, Issue:1 Topics: Acetaldehyde; Adult; Albumins; Alcoholism; Blood Proteins; Diazepam; Female; Humans; Male; Middle Ag	1986
Effects of chronic alcohol intake on anesthetic responses to diazepam and thiopental in rats. Anesthesiology, 1986, Volume: 65, Issue:2 Topics: Alcoholism; Anesthesia, Intravenous; Animals; Body Weight; Diazepam; Drug Interactions; Drug Toleran	1986
Differential diagnosis of weakness--a common geriatric symptom. Geriatrics, 1986, Volume: 41, Issue:4 Topics: Aged; Alcoholism; Arthritis; Cardiovascular Diseases; Depression; Diabetes Complications; Diagnosis,	1986
Acetaldehyde adducts with serum proteins: effect on diazepam and phenytoin binding. Pharmacology, 1986, Volume: 32, Issue:3 Topics: Acetaldehyde; Alcoholism; Binding Sites; Blood Proteins; Diazepam; Ethanol; Humans; In Vitro Techniq	1986
Simultaneous bilateral anterior and posterior shoulder dislocations. The American journal of emergency medicine, 1985, Volume: 3, Issue:4 Topics: Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Humans; Male; Middle Aged; Psychoses, Alcoholic;	1985
The effects of alcohol, barbiturate, and diazepam on hypothalamic-pituitary-adrenal function in chronic alcoholics. Lancet (London, England), 1972, Nov-11, Volume: 2, Issue:7785 Topics: Adrenal Glands; Adult; Aged; Alcoholism; Barbiturates; Blood Glucose; Diazepam; Ethanol; Humans; Hyd	1972
[Voluntary detoxification therapy of young drug addicts in a medical clinic (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1974, Nov-29, Volume: 116, Issue:48 Topics: Adult; Alcoholism; Barbiturates; Cannabis; Diazepam; Drug Combinations; Drug Therapy, Combination; F	1974
Drug therapy in alcoholism. It is especially important in the prevention of such complications as seizures, DT's, Wernicke's encephalopathy, or polyneuritis. IMJ. Illinois medical journal, 1971, Volume: 139, Issue:6 Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Diazepam; Disulfiram; Humans; Hydroxy	1971
[Apomorphine and propranolol in the treatment of alcoholism]. Lakartidningen, 1974, Aug-21, Volume: 71, Issue:34 Topics: Alcoholism; Apomorphine; Diazepam; Humans; Propranolol	1974
Editorial: Hair of the dog. British medical journal, 1974, Sep-07, Volume: 3, Issue:5931 Topics: Alcoholism; Diazepam; Drug Tolerance; Gastritis; Gastroscopy; Humans; Premedication	1974
Tranquillisers and alcoholism. The New Zealand medical journal, 1972, Volume: 75, Issue:477 Topics: Alcoholism; Diazepam; Humans; Tranquilizing Agents	1972
Quantitative study of alcohol withdrawal signs in mice. Annals of the New York Academy of Sciences, 1973, Apr-30, Volume: 215 Topics: Alcoholism; Animals; Barbiturates; Behavior, Animal; Chlorpromazine; Diazepam; Disease Models, Anima	1973
Letter: Cardiac arrest with diazepam. Journal of oral surgery (American Dental Association : 1965), 1974, Volume: 32, Issue:11 Topics: Alcoholism; Diazepam; Heart Arrest; Humans; Respiratory Insufficiency	1974
Prescription of psychotropic drugs by general practitioners. 1. General. The Medical journal of Australia, 1973, Mar-24, Volume: 1, Issue:12 Topics: Adjustment Disorders; Adolescent; Adult; Aged; Alcoholism; Antidepressive Agents; Anxiety Disorders;	1973
Clinical toxicity of chlordiazepoxide and diazepam in relation to serum albumin concentration: a report from the Boston Collaborative Drug Surveillance Program. European journal of clinical pharmacology, 1974, Jul-26, Volume: 7, Issue:4 Topics: Age Factors; Alcoholism; Anxiety; Chlordiazepoxide; Coffee; Depression; Diazepam; Female; Humans; Le	1974
Rupture of esophagus during use of Mengstaken-Blakemore tube. Postgraduate medicine, 1974, Volume: 56, Issue:2 Topics: Alcoholism; Diazepam; Duodenum; Enteritis; Esophageal and Gastric Varices; Esophageal Diseases; Esop	1974
Parenteral diazepam in status epilepticus. Neurology, 1969, Volume: 19, Issue:4 Topics: Adolescent; Adult; Aged; Alcoholism; Brain Neoplasms; Child; Child, Preschool; Diazepam; Electroence	1969
The effect of sedatives on the metabolic rate during alcohol withdrawal. Quarterly journal of studies on alcohol, 1972, Volume: 33, Issue:1 Topics: Adult; Alcoholism; Amobarbital; Basal Metabolism; Chlormethiazole; Chlorpromazine; Depression, Chemi	1972
Acute delirium in amitriptyline-perphenazine therapy of alcoholism. Clinical toxicology, 1971, Volume: 4, Issue:1 Topics: Acute Disease; Adult; Alcoholism; Amitriptyline; Delirium; Diazepam; Drug Combinations; Hallucinatio	1971
Diphenylhydantoin and alcohol withdrawal. JAMA, 1971, May-03, Volume: 216, Issue:5 Topics: Alcoholism; Diazepam; Drug Synergism; Humans; Phenytoin; Substance Withdrawal Syndrome	1971
Diazepam, alcohol, and barbiturate abuse. British medical journal, 1971, Nov-06, Volume: 4, Issue:5783 Topics: Adult; Alcoholism; Barbiturates; Diazepam; Female; Humans; Substance-Related Disorders	1971
Clinical and electroencephalographic assessment of diazepam in liver disease. British medical journal, 1971, Oct-30, Volume: 4, Issue:5782 Topics: Alcoholism; Budd-Chiari Syndrome; Cholestasis; Chronic Disease; Consciousness; Diazepam; Electroence	1971
Alcoholism in women. Archives of general psychiatry, 1971, Volume: 25, Issue:6 Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anxiety; Chlordiazepoxide; Depression; Diazepam; Female;	1971
[Misuse of bezodiazepin derivatives in alcoholics]. The British journal of addiction to alcohol and other drugs, 1966, Volume: 61, Issue:3 Topics: Alcoholism; Chlordiazepoxide; Diazepam; Humans; Substance-Related Disorders	1966
Facultative drug treatmt of neurotic complaints in alcoholics. The British journal of addiction to alcohol and other drugs, 1970, Volume: 65, Issue:3 Topics: Adult; Aged; Alcoholism; Atropa belladonna; Barbiturates; Diazepam; Humans; Male; Meprobamate; Middl	1970
Librium and valium. The Medical letter on drugs and therapeutics, 1969, Oct-03, Volume: 11, Issue:20 Topics: Alcoholism; Anxiety; Chlordiazepoxide; Diazepam; Humans; Mental Disorders; Seizures; Suicide	1969
Diazepam injectable as premedication for electrical cardioversion. Canadian Medical Association journal, 1970, Dec-19, Volume: 103, Issue:13 Topics: Adult; Aged; Alcoholism; Anesthesia, Intravenous; Arrhythmias, Cardiac; Diazepam; Electric Countersh	1970
[Modern therapy of alcoholism]. Il Policlinico. Sezione pratica, 1970, Jan-05, Volume: 77, Issue:1 Topics: Alcoholism; Chlordiazepoxide; Coma; Diazepam; Fructose; Humans; Hypotension; Psychoses, Alcoholic; S	1970
[Seduxen treatment of status epilepticus]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1971, Volume: 71, Issue:3 Topics: Adolescent; Adult; Aged; Alcoholism; Craniocerebral Trauma; Diazepam; Electroencephalography; Epilep	1971
A problem of prolonged oral intubation: case report. Canadian Anaesthetists' Society journal, 1971, Volume: 18, Issue:2 Topics: Alcoholism; Diazepam; Humans; Intubation, Intratracheal; Male; Middle Aged; Mouth; Substance Withdra	1971
[Use of valium in clinical psychiatry]. Die Medizinische Welt, 1967, Jul-08, Volume: 27 Topics: Alcoholism; Diazepam; Humans; Intellectual Disability; Psychotic Disorders; Substance-Related Disord	1967
The intravenous use of diazepam in focal status epilepticus. Southern medical journal, 1969, Volume: 62, Issue:4 Topics: Adult; Aged; Alcoholism; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Injections, Int	1969
Two severe reactions to benzodiazepine compounds. The American journal of psychiatry, 1965, Volume: 122, Issue:5 Topics: Adult; Alcoholism; Ataxia; Chlordiazepoxide; Diazepam; Drug Synergism; Humans; Male; Middle Aged; Mu	1965
[Clinical experiences with methyldiazepinone in high doses]. Minerva medica, 1966, Feb-28, Volume: 57, Issue:17 Topics: Adolescent; Adult; Aged; Alcoholism; Depression; Diazepam; Female; Humans; Male; Mental Disorders; M	1966
Diazepam (valium) very high dosage: longitudinal and single case study. Western medicine; the medical journal of the west, 1966, Volume: 7, Issue:5 Topics: Alcoholism; Diazepam; Humans; Male; Middle Aged	1966

diazepam and Alcohol Abuse

Research Excerpts

Research

Studies (231)

Authors

Clinical Trials (4)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Patel, L	1
Beddow, D	1
Kirven, J	1
Smith, CS	1
Hanovich, S	1
Holaday, K	1
Agboto, V	1
St Hill, CA	1
Skryabin, VY	3
Zastrozhin, M	1
Torrado, M	1
Grishina, E	1
Ryzhikova, K	1
Shipitsyn, V	1
Galaktionova, T	1
Bryun, E	1
Sychev, D	1
Bahji, A	1
Bach, P	1
Danilewitz, M	1
Crockford, D	1
El-Guebaly, N	1
Devoe, DJ	1
Saitz, R	2
Franck, J	1
Lauschke, VM	1
Zastrozhin, MS	2
Shipitsyn, VV	2
Bryun, EA	2
Sychev, DA	2
Williams, J	1
Collins, L	1
Norman, A	1
O'Neill, H	1
Lloyd-Jones, M	1
Ogden, E	1
Bonomo, Y	1
Pastor, A	1
Crunelle, CL	1
Jegham, S	1
Vanderbruggen, N	1
Matthys, F	1
Lorenz-Guertin, JM	1
Povysheva, N	1
Chapman, CA	1
MacDonald, ML	1
Fazzari, M	1
Nigam, A	1
Nuwer, JL	1
Das, S	1
Brady, ML	1
Vajn, K	1
Bambino, MJ	1
Weintraub, ST	1
Johnson, JW	1
Jacob, TC	1
Scheuermeyer, FX	1
Miles, I	1
Lane, DJ	1
Grunau, B	1
Grafstein, E	1
Sljivic, I	1
Duley, S	1
Yan, A	1
Chiu, I	1
Kestler, A	1
Barbic, D	1
Moe, J	1
Slaunwhite, A	1
Nolan, S	1
Ti, L	1
Innes, G	1
Choi, HY	1
Seo, JS	1
Lee, SK	1
García-Méndez, N	1
Briceño-Santana, M	1
Totomoch-Serra, A	1
Manterola, C	1
Otzen, T	1
Valdez, PS	1
Campos-Durán, R	1
Reyna, GC	1
Grishina, EA	1
Ryzhikova, KA	1
V Barna, I	1
Galaktionova, TE	1
Ivanov, AV	1
Sorokin, AS	1
Sychla, H	1
Gründer, G	1
Lammertz, SE	1
Simioni, N	1
Labreuche, J	1
Behal, H	1
Cottencin, O	1
Rolland, B	1
da Costa E Silva, LD	1
Pereira, P	1
Regner, GG	1
Boaretto, FBM	1
Hoffmann, C	1
Pflüger, P	1
da Silva, LL	1
Steffens, LR	1
Morás, AM	1
Moura, DJ	1
Picada, JN	1
Martinez, L	1
Vorspan, F	1
Declèves, X	1
Azuar, J	1
Fortias, M	1
Questel, F	1
Dereux, A	1
Grichy, L	1
Barreteau, H	1
Bellivier, F	1
Lépine, JP	1
Bloch, V	1
Oliveras, C	1
Fortea, A	1
Espinosa, L	1
Barrio, P	1
Lligoña, A	1
Balcells-Olivero, M	1
Jahn, A	1
Bodreau, C	1
Farthing, K	1
Elbarbry, F	1
Gajbhiye, SV	1
Tripathi, RK	1
Petare, A	1
Potey, AV	1
Shankar, A	1
Dominguez, G	1
Henkous, N	1
Pierard, C	1
Belzung, C	1
Mons, N	1
Beracochea, D	1
Azanza Balmori, A	1
García Álvarez, G	1
Rodríguez Turiel, C	1
Povedano Suárez, EA	1
Muquebil Ali Al Shaban Rodríguez, OW	1
Calvo, ME	1
Gunnarsson, T	1
Smith, L	1
Hao, M	1
Benedict, NJ	1
Wong, A	1
Cassidy, E	1
Lohr, BR	1
Pizon, AF	1
Smithburger, PL	1
Falcione, BA	1
Kirisci, L	1
Kane-Gill, SL	1
Lee, JA	1
Duby, JJ	1
Cocanour, CS	1
de Timary, P	1
Cordovil de Sousa Uva, M	1
Denoël, C	1
Hebborn, L	1
Derely, M	1
Desseilles, M	1
Luminet, O	1
Ishii, N	1
Terao, T	1
Araki, Y	1
Hatano, K	1
Qi, Z	1
Tretter, F	1
Voit, EO	1
Motaghinejad, M	1
Bangash, MY	1
Motaghinejad, O	1
Holzbach, R	1
Ihlow, C	1
Takla, T	1
Kemper, U	1
Naber, D	1
Jose, M	1
Mathaiyan, J	1
Kattimani, S	1
Adithan, S	1
Chandrasekaran, A	1
Kuypers, MI	1
Lieshoud, JR	1
van der Linden, PD	1
Touw, DJ	1
Deenik, W	1
Boeke, GM	1
Zoga, M	1
Nikou, T	1
Ioannidis, A	1
Tzavellas, E	1
Paparrigopoulos, T	1
Lambrokostopoulos, KT	1
Vasdekis, VG	1
Magana, M	1
Chatzipanagiotou, S	1
Laqueille, X	1
Launay, C	1
Dervaux, A	1
Kanit, M	1
Rubio, G	1
López-Muñoz, F	1
Ponce, G	1
Pascual, JM	1
Martínez-Gras, I	1
Ferre, F	1
Jiménez-Arriero, MÁ	1
Alamo, C	1
Richter, C	1
Hinzpeter, A	1
Schmidt, F	1
Kienast, T	1
Preuss, UW	1
Plenge, T	1
Heinz, A	1
Schaefer, M	1
Jacques, D	1
Zdanowicz, N	1
Reynaert, C	1
Janne, P	1
Timary, P	1
Cagetti, E	2
Liang, J	2
Spigelman, I	2
Olsen, RW	2
Devi, G	1
HOFF, EC	1
ROSA, JJ	1
MIRVILLANUE, VA	1
MACULANS, GA	1
DITMAN, KS	2
GOTTLIEB, L	1
LAMBERT, PA	1
DELAUNAY, J	1
MARCOU, G	1
BURDINE, WE	1
FONTAN, M	1
CHAMBERS, JF	1
SCHULTZ, JD	1
Dobrydnjov, I	1
Axelsson, K	1
Berggren, L	1
Samarütel, J	1
Holmström, B	1
CROMWELL, HA	1
Poulos, CX	1
Zack, M	1
Chwaluk, P	1
Besheer, J	1
Hodge, CW	1
Vorma, H	1
Naukkarinen, HH	1
Sarna, SJ	1
Kuoppasalmi, KI	1
Charlton, BG	1
Favre, JD	1
Allain, H	1
Aubin, HJ	1
Frija-Orvoen, E	1
Gillet, C	1
Lejoyeux, M	1
Payen, A	1
Weber, M	1
Garcia-Acosta, S	1
Kermadi, I	1
Dib, M	1
Chichakli, H	1
Frosch, PJ	1
Brinkmeier, T	1
Krupitsky, EM	2
Rudenko, AA	1
Burakov, AM	4
Slavina, TY	1
Grinenko, AA	1
Pittman, B	1
Gueorguieva, R	1
Petrakis, IL	1
Zvartau, EE	1
Krystal, JH	1
Pavlic, M	1
Libiseller, K	1
Hermann, M	1
Hengster, P	1
Margreiter, R	1
Wurm, M	1
Nava, F	1
Premi, S	1
Manzato, E	1
Campagnola, W	1
Lucchini, A	1
Gessa, GL	1
Kochi, Y	1
Fukushima, H	1
Suwaki, H	1
Kato, M	1
Matsushita, Y	1
Miyakawa, T	1
Akanashi, T	1
Higuchi, S	1
Weinberg, JA	1
Magnotti, LJ	1
Fischer, PE	1
Edwards, NM	1
Schroeppel, T	1
Fabian, TC	1
Croce, MA	1
Burov, IuV	3
Iukhananov, RIu	2
Maĭskiĭ, AI	1
Greenblatt, DJ	11
Shader, RI	6
Abernethy, DR	1
Acuda, SW	1
Francis, DA	1
Nelson, AA	1
Hemmingsen, R	2
Braestrup, C	1
Nielsen, M	1
Barry, DI	1
Lil'in, ET	1
Drozdov, ES	1
Evdokimova, LG	1
Vavilova, TA	1
Kazanskaia, AV	1
Ryser, PE	1
Abou-Saleh, MT	1
Merry, J	2
Coppen, A	1
Walters, L	1
Nel, P	1
Sellers, EM	5
Sandor, P	1
Giles, HG	2
Khouw, V	1
Mark, JB	1
Greenberg, LM	1
Pristach, CA	1
Smith, CM	1
Whitney, RB	1
Schwarz, E	1
Kielholz, P	1
Hobi, V	1
Goldberg, L	2
Hofstetter, M	1
Ladewig, D	1
Kolin, IS	1
Linet, OI	1
Cohen, MS	1
Herrington, RE	1
Benzer, DG	1
Jacobson, GR	1
Hawkins, MK	1
Lessenger, JE	1
Cohen, S	1
Busch, KT	1
Schulz, H	1
Hammerle, AF	1
Hörtnagl, H	1
Geissler, D	1
Hackl, JM	1
Strickland, RA	1
Berge, KH	1
Salloum, IM	1
Cornelius, JR	1
Daley, DC	1
Thase, ME	1
Cohen, SI	1
Johnson, FY	1
Adinoff, B	1
Krupitskiĭ, EM	2
Ivanov, VB	2
Karandashova, GF	1
Lapin, IP	2
Grinenko, AIa	2
Borodkin, IuS	2
Cowley, DS	4
Roy-Byrne, PP	4
Radant, A	1
Hommer, DW	2
Vitaliano, PP	1
Godon, C	2
Robledo, P	1
Lumeng, L	1
Li, TK	1
Ehlers, CL	1
Worner, TM	1
Krandashova, GF	1
Ciraulo, DA	3
DuPont, RL	1
Griffiths, RR	1
Kosten, TR	1
Romach, MK	1
Woody, GE	1
Friedman, LS	1
Mayo-Smith, MF	1
Hyman, SE	1
Zorzon, M	1
Masè, G	1
Biasutti, E	1
Vitrani, B	1
Cazzato, G	1
Klijnsma, MP	1
Cameron, ML	1
Burns, TP	1
McGuigan, SM	1
Kramer, GL	1
Petty, F	1
Dodd, PR	4
Thomas, GJ	2
McCloskey, A	1
Crane, DI	1
Smith, ID	1
Wu, WJ	1
Pruett, SB	1
Mezciems, PE	1
Kril, JJ	2
Watson, WE	2
Johnston, GA	2
Harper, CG	2
Ivanets, NN	1
Anokhina, IP	1
Kogan, BM	1
Chirko, VV	1
Nebarakova, TP	1
Rusinov, AV	1
Garretty, DJ	1
Wolff, K	1
Hay, AW	1
Raistrick, D	1
Barnhill, JG	1
Ciraulo, AM	1
Sarid-Segal, O	1
Knapp, C	1
Shirakura, K	1
Hayashida, M	1
Anton, RF	1
Kranzler, HR	1
McEvoy, JP	1
Moak, DH	1
Bianca, R	1
Ajima, M	1
Usuki, K	1
Igarashi, A	1
Okazaki, R	1
Hamano, K	1
Urabe, A	1
Totsuka, Y	1
Maes, M	1
Lin, A	1
Bonaccorso, S	1
Vandoolaeghe, E	1
Song, C	1
Goossens, F	1
De Meester, I	1
Degroote, J	1
Neels, H	1
Scharpé, S	1
Janca, A	1
Wooddell, WJ	1
Iwata, N	1
Radel, M	1
Goldman, D	1
Charney, DA	1
Paraherakis, AM	1
Gill, KJ	1
Signore, AP	1
Yeh, HH	1
George, S	1
Chin, CN	1
Martijena, ID	1
Lacerra, C	1
Bustos, SG	1
Molina, VA	1
Petry, NM	1
Schuckit, MA	4
Smith, TL	1
Williams, S	1
Mielke, DH	1
Gallant, DM	1
McFarlain, RA	1
Rosenbaum, AH	1
Niven, RG	1
Hanson, NP	1
Swanson, DW	1
Fialkov, MJ	1
Gottschalk, LA	2
Cohn, JB	2
MacLeod, SM	1
Billings, BJ	1
Martin, PR	1
Marshman, JA	1
Koeppen, D	1
Franken, R	1
Seale, FE	1
Harry, TV	1
Glatt, MM	1
Miyasato, K	2
Stitzer, ML	1
Bigelow, GE	1
Liebson, I	1
Coleman, JH	1
Evans, WE	1
Becker, CE	2
Roe, R	1
Scott, R	1
Tong, T	1
Boerner, U	1
Luce, J	1
Kissin, B	1
Bissell, LC	1
Keeler, MH	1
Taylor, CI	1
Miller, WC	1
Wozniak, KJ	1
Silverman, EM	1
Woo, E	1
Pond, SM	1
Phillips, M	1
Benowitz, NL	1
Galinsky, RE	1
Tong, TG	1
Tennant, FS	1
Deutsch, JA	1
Walton, NY	1
Ferko, AP	1
Bobyock, E	1
Chernick, WS	1
Thompson, WL	2
Verbanck, M	1
Pelc, I	1
Carlsson, C	4
Fasth, BG	2
Glass, GS	1
Dysken, MW	1
Chan, CH	1
Thiessen, JJ	1
Denbeigh, P	1
Dolman, L	1
Johnson, AD	1
Maddrey, WL	1
Kryspin-Exner, K	2
Demel, I	1
Warkany, J	1
Shaul, WL	1
Emery, H	1
Hall, JG	1
Klotz, U	1
Avant, GR	1
Hoyumpa, A	1
Schenker, S	1
Wilkinson, GR	1
Vaag, UH	1
Berggrav, E	1
Sellman, R	2
Pekkarinen, A	2
Kangas, L	1
Raijola, E	2
Kanto, J	1
Sullivan, JT	1
Korpi, ER	1
Uusi-Oukari, M	1
Wegelius, K	1
Casanova, M	1
Zito, M	1
Kleinman, JE	1
Ries, R	1
Walker, RD	1
Samson, HH	1
Piepho, R	1
Whelton, A	1
Mayor, G	1
Neu, H	1
Laddu, A	1
Gewiss, M	1
Heidbreder, C	1
Opsomer, L	1
Durbin, P	1
De Witte, P	1
Duthie, LA	2
Mahler, HI	2
Irwin, M	3
Monteiro, MG	3
de Witt, H	1
Hauger, RL	1
de Wit, H	1
Collins, MN	1
Burns, T	1
van den Berk, PA	1
Tubman, GF	1
Baron, DH	1
Sands, BF	1
Ulrichsen, J	1
Clemmesen, L	1
Barry, D	1
van Sweden, B	1
Grässler, W	1
Schwarz-Ottersbach, E	1
Gundlach, AL	1
Davies, N	1
Orekhov, SN	3
Vedernikova, NN	3
Boiadzhieva, N	2
Ball, JC	1
Corty, E	1
Erdlen, DL	1
Nurco, DN	1
Miller, TP	1
Taylor, JL	1
Tinklenberg, JR	1
Borisova, IP	1
Kulkarni, SK	1
Parale, MP	1
Kulkarni, GK	1
Foy, A	1
Glen, I	1
Skinner, F	1
Glen, E	1
MacDonell, L	1
Lucas, D	2
Pennec, Y	1
Ménez, JF	2
Floch, HH	2
Le Menn, G	1
Newman, LM	1
Curran, MA	1
Becker, GL	1
Gordon, M	1
Daniel, JY	1
Bardou, LG	1
Griffith, JD	1
Jasinski, DR	1
Casten, GP	1
McKinney, GR	1
Aufderheide, TP	1
Frascone, RJ	1
Cicero, JJ	1
Marks, V	1
Whitlock, FA	1
Price, J	1
Friess, G	1
Oge, V	1
Burns, CR	1
Goldstein, DB	1
Uphold, JD	1
Block, C	1
Borendal-Jansson, B	1
Rowe, IL	1
Koch-Weser, J	1
Hamm, DD	1
Papp, JP	1
Hofmann, KW	1
Manach, J	1
Sögtrop, HH	1
Butterworth, AT	1
Watts, RD	1
Johansson, T	1
Zbinden, G	1
Randall, LO	1
Nicol, CF	1
Tutton, JC	1
Smith, BH	1
Learoyd, BM	1
Rawson, RA	1
Lipscomb, WR	1
Rozynko, J	1
Gessner, PK	1
Clare, AW	1
Murray-Lyon, IM	1
Young, J	1
Parkes, JD	1
Knill-Jones, RP	1
Williams, R	1
Belfer, ML	1
Carroll, M	1
Harmatz, JS	1
Vajda, A	1
Rotem, CE	1
Iandolo, C	1
Bogolepov, NK	1
Burd, GS	1
Fedin, AI	1
Adamson, DH	1
Dengler, K	1
Glaesel, HU	1
Little, SC	1
Green, J	1
Daly, RJ	1
Kane, FJ	1
Malagoli, G	1
Benor, D	1