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diazepam and Agoraphobia

diazepam has been researched along with Agoraphobia in 25 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Agoraphobia: Obsessive, persistent, intense fear of open places.

Research Excerpts

ExcerptRelevanceReference
"Thirty out-patients suffering from panic disorders associated with agoraphobia were enrolled in a double-blind, controlled trial to compare the effectiveness and tolerability of etizolam and placebo."9.06Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study. ( Ecari, U; Savoldi, F; Somenzini, G, 1990)
"The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia."9.05Diazepam and propranolol in panic disorder and agoraphobia. ( Anderson, DJ; Clancy, J; Crowe, RR; Ghoneim, MM; Hinrichs, JV; Noyes, R; Slymen, DJ, 1984)
"A multi-centre, double-blind trial was carried out in general practice to compare the effectiveness and tolerability of clomipramine and diazepam in patients with agoraphobia or social phobia."9.05Clomipramine and diazepam in the treatment of agoraphobia and social phobia in general practice. ( Allsopp, LF; Cooper, GL; Poole, PH, 1984)
"The effects of oral doses of diazepam (single dose of 10 mg and a median dose of 30 mg/day for 2 weeks) and propranolol (single dose of 80 mg and a median dose of 240 mg/day for 2 weeks) on psychological performance of patients with panic disorders and agoraphobia were investigated in a double-blind, randomized and crossover design."9.05Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia. ( Anderson, DJ; Ghoneim, MM; Hinrichs, JV; Noyes, R, 1984)
"Fifty-seven chronic agoraphobic outpatients were treated by 12 hours of exposure in vivo on four days over two weeks to check the effects of oral diazepam versus placebo during group exposure, group versus individual exposure, and high versus medium anxiety arousal during individual exposure."9.04Exposure in vivo of agoraphobics: contributions of diazepam, group exposure, and anxiety evocation. ( Hafner, J; Marks, I, 1976)
"Thirty out-patients suffering from panic disorders associated with agoraphobia were enrolled in a double-blind, controlled trial to compare the effectiveness and tolerability of etizolam and placebo."5.06Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study. ( Ecari, U; Savoldi, F; Somenzini, G, 1990)
"The response to diazepam and propranolol hydrochloride was compared in 21 patients who (with one exception) met DSM-III criteria for panic disorder and agoraphobia."5.05Diazepam and propranolol in panic disorder and agoraphobia. ( Anderson, DJ; Clancy, J; Crowe, RR; Ghoneim, MM; Hinrichs, JV; Noyes, R; Slymen, DJ, 1984)
"Thirty-six patients with generalised anxiety disorder, panic disorder or agoraphobia with panic attacks, diagnosed by DSM-III criteria, were treated with a new non-benzodiazepine anti-anxiety drug, buspirone, and with diazepam and placebo, in a cross-over design."5.05Anxiety in primary care: is short-term drug treatment appropriate? ( Owen, R; Tyrer, P, 1984)
"A multi-centre, double-blind trial was carried out in general practice to compare the effectiveness and tolerability of clomipramine and diazepam in patients with agoraphobia or social phobia."5.05Clomipramine and diazepam in the treatment of agoraphobia and social phobia in general practice. ( Allsopp, LF; Cooper, GL; Poole, PH, 1984)
"The effects of oral doses of diazepam (single dose of 10 mg and a median dose of 30 mg/day for 2 weeks) and propranolol (single dose of 80 mg and a median dose of 240 mg/day for 2 weeks) on psychological performance of patients with panic disorders and agoraphobia were investigated in a double-blind, randomized and crossover design."5.05Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia. ( Anderson, DJ; Ghoneim, MM; Hinrichs, JV; Noyes, R, 1984)
"Fifty-seven chronic agoraphobic outpatients were treated by 12 hours of exposure in vivo on four days over two weeks to check the effects of oral diazepam versus placebo during group exposure, group versus individual exposure, and high versus medium anxiety arousal during individual exposure."5.04Exposure in vivo of agoraphobics: contributions of diazepam, group exposure, and anxiety evocation. ( Hafner, J; Marks, I, 1976)
" Self-ratings of avoidance and distress, frequency of panic attacks, diazepam use, and negative cognitions decreased with treatment."3.68Cognitive-behavioral treatment for panic disorder with gastrointestinal symptoms: a case study. ( Eldridge, GD; Holborn, SW; Walker, JR, 1993)
"The diazepam pretreatment condition was associated with a significantly increased infusion duration and a significant attenuation of rate of API symptom increase in response to lactate."2.68Effects of intravenous diazepam pretreatment on lactate-induced panic. ( Campeas, RB; Coplan, JD; Davies, SO; Dillon, DJ; Fyer, AJ; Gorman, JM; Klein, DF; Liebowitz, MR; Martinez, J, 1995)
"The greatest problem with combined treatment is relapse after drug discontinuance."2.40Benzodiazepines and exposure-based cognitive behavior therapies for panic disorder: conclusions from combined treatment trials. ( Bruce, TJ; Spiegel, DA, 1997)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199015 (60.00)18.7374
1990's9 (36.00)18.2507
2000's1 (4.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gruber, EN1
Dordević, V1
Biocina-Martić, S1
Agius, M1
Marks, I2
Noyes, R4
Anderson, DJ2
Clancy, J1
Crowe, RR1
Slymen, DJ1
Ghoneim, MM2
Hinrichs, JV2
Tyrer, P1
Owen, R1
Allsopp, LF1
Cooper, GL1
Poole, PH1
Davis, JM1
Nasr, S1
Spira, N1
Vogel, C1
Pohl, R2
Berchou, R1
Rainey, JM1
Wardle, J2
Hayward, P2
Higgitt, A2
Stabl, M1
Blizard, R1
Gray, J2
Eldridge, GD1
Walker, JR1
Holborn, SW1
Balon, R1
Yeragani, VK1
Merlos, B1
Sherwood, P1
Liebowitz, MR1
Coplan, JD1
Martinez, J1
Fyer, AJ1
Dillon, DJ1
Campeas, RB1
Davies, SO1
Gorman, JM1
Klein, DF1
Spiegel, DA1
Bruce, TJ1
Hafner, J1
Hafner, RJ1
Mountjoy, CQ1
Roth, M1
Garside, RF1
Leitch, IM1
McElroy, SL1
Keck, PE1
Lawrence, JM1
Savoldi, F1
Somenzini, G1
Ecari, U1
Lopez, AL1
Kathol, RG1
Lilienfeld, SO1
Jacob, RG1
Furman, JM1
Dager, SR1
Cowley, DS1
Dunner, DL1
Coryell, W1
Lutz, EG1
Lutz, MB1
Lutz, GE1
Finkel, JA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of Pre- and Post-Synaptic Dopamine Function in Developmental Stuttering Using 11C-Raclopride and Positron Emission Tomography[NCT00024960]12 participants (Actual)Observational2001-10-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for diazepam and Agoraphobia

ArticleYear
Benzodiazepines and exposure-based cognitive behavior therapies for panic disorder: conclusions from combined treatment trials.
    The American journal of psychiatry, 1997, Volume: 154, Issue:6

    Topics: Agoraphobia; Animals; Benzodiazepines; Clinical Trials as Topic; Cognitive Behavioral Therapy; Combi

1997

Trials

15 trials available for diazepam and Agoraphobia

ArticleYear
Comparative studies on benzodiazepines and psychotherapies.
    L'Encephale, 1983, Volume: 9, Issue:4 Suppl 2

    Topics: Agoraphobia; Anxiety; Clinical Trials as Topic; Diazepam; Double-Blind Method; Humans; Palliative Ca

1983
Diazepam and propranolol in panic disorder and agoraphobia.
    Archives of general psychiatry, 1984, Volume: 41, Issue:3

    Topics: Adult; Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Depression; Diazepam; Double-Blind

1984
Anxiety in primary care: is short-term drug treatment appropriate?
    Journal of psychiatric research, 1984, Volume: 18, Issue:1

    Topics: Adult; Agoraphobia; Anxiety Disorders; Buspirone; Clinical Trials as Topic; Diazepam; Female; Humans

1984
Clomipramine and diazepam in the treatment of agoraphobia and social phobia in general practice.
    Current medical research and opinion, 1984, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Aged; Agoraphobia; Clinical Trials as Topic; Clomipramine; Diazepam; Double-Blind

1984
Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia.
    Neuropsychobiology, 1984, Volume: 11, Issue:4

    Topics: Adult; Agoraphobia; Clinical Trials as Topic; Cognition; Diazepam; Double-Blind Method; Fear; Female

1984
Anxiety: differential diagnosis and treatment from a biologic perspective.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:11 Pt 2

    Topics: Agoraphobia; Anxiety Disorders; Clinical Trials as Topic; Diagnosis, Differential; Diazepam; Double-

1981
Effects of concurrent diazepam treatment on the outcome of exposure therapy in agoraphobia.
    Behaviour research and therapy, 1994, Volume: 32, Issue:2

    Topics: Adult; Agoraphobia; Combined Modality Therapy; Desensitization, Psychologic; Diazepam; Dose-Response

1994
Changes in appetite and weight during the pharmacological treatment of patients with panic disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1993, Volume: 38, Issue:1

    Topics: Adult; Agoraphobia; Appetite; Body Weight; Diazepam; Dietary Carbohydrates; Double-Blind Method; Fem

1993
Effects of intravenous diazepam pretreatment on lactate-induced panic.
    Psychiatry research, 1995, Sep-29, Volume: 58, Issue:2

    Topics: Adult; Agoraphobia; Anti-Anxiety Agents; Arousal; Blood Pressure; Diazepam; Fear; Female; Heart Rate

1995
Changes in "withdrawal symptoms" following discontinuation of low-dose diazepam.
    Psychopharmacology, 1996, Volume: 125, Issue:4

    Topics: Adult; Agoraphobia; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; H

1996
Exposure in vivo of agoraphobics: contributions of diazepam, group exposure, and anxiety evocation.
    Psychological medicine, 1976, Volume: 6, Issue:1

    Topics: Administration, Oral; Agoraphobia; Anxiety; Behavior Therapy; Chronic Disease; Desensitization, Psyc

1976
A clinical trial of phenelzine in anxiety depressive and phobic neuroses.
    The British journal of psychiatry : the journal of mental science, 1977, Volume: 131

    Topics: Adjustment Disorders; Adolescent; Adult; Aged; Agoraphobia; Anxiety Disorders; Clinical Trials as To

1977
Etizolam versus placebo in the treatment of panic disorder with agoraphobia: a double-blind study.
    Current medical research and opinion, 1990, Volume: 12, Issue:3

    Topics: Adult; Agoraphobia; Chronic Disease; Diazepam; Double-Blind Method; Drug Administration Schedule; Fe

1990
Reduction in urinary free cortisol during benzodiazepine treatment of panic disorder.
    Psychoneuroendocrinology, 1990, Volume: 15, Issue:1

    Topics: Adult; Agoraphobia; Alprazolam; Benzodiazepines; Depression; Diazepam; Fear; Female; Humans; Hydroco

1990
Placebo response in panic disorder.
    The American journal of psychiatry, 1988, Volume: 145, Issue:9

    Topics: Adult; Agoraphobia; Alprazolam; Anxiety Disorders; Clinical Trials as Topic; Dexamethasone; Diazepam

1988

Other Studies

9 other studies available for diazepam and Agoraphobia

ArticleYear
"My new Alfa Romeo GT is not in the garage any more": Cognitive behavioural therapy of panic disorder with agoraphobia co morbid with psychosis.
    Psychiatria Danubina, 2006, Volume: 18, Issue:3-4

    Topics: Adult; Agoraphobia; Antipsychotic Agents; Atenolol; Benzodiazepines; Cognitive Behavioral Therapy; C

2006
Tricyclic antidepressants and monoamine oxidase inhibitors in the treatment of agoraphobia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Agoraphobia; Antidepressive Agents, Tricyclic; Clomipramine; Diazepam; Double-Blind Method; Humans;

1982
Cognitive-behavioral treatment for panic disorder with gastrointestinal symptoms: a case study.
    Journal of behavior therapy and experimental psychiatry, 1993, Volume: 24, Issue:4

    Topics: Adult; Agoraphobia; Behavior Therapy; Diazepam; Fecal Incontinence; Female; Humans; Panic Disorder

1993
Fresh symptom emergence after intensive behaviour therapy.
    The British journal of psychiatry : the journal of mental science, 1976, Volume: 129

    Topics: Agoraphobia; Behavior Therapy; Desensitization, Psychologic; Diazepam; Evaluation Studies as Topic;

1976
Treatment of panic disorder and benzodiazepine withdrawal with valproate.
    The Journal of neuropsychiatry and clinical neurosciences, 1991,Spring, Volume: 3, Issue:2

    Topics: Adult; Agoraphobia; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Panic Diso

1991
Vestibular dysfunction followed by panic disorder with agoraphobia.
    The Journal of nervous and mental disease, 1989, Volume: 177, Issue:11

    Topics: Adult; Agoraphobia; Avoidance Learning; Diazepam; Fear; Humans; Male; Panic; Vestibular Diseases

1989
Biological markers in panic states: lactate-induced panic and mitral valve prolapse.
    Biological psychiatry, 1987, Volume: 22, Issue:3

    Topics: Adolescent; Adult; Aged; Agoraphobia; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Creatinine

1987
Agoraphobia and paroxysmal cerebral dysrhythmia.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:9

    Topics: Agoraphobia; Diazepam; Electroencephalography; Epilepsy; Humans; Phobic Disorders

1987
Diazepam in a patient with chronic schizophrenia complicated by agoraphobia.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:1

    Topics: Adult; Agoraphobia; Behavior Therapy; Combined Modality Therapy; Diazepam; Humans; Male; Phobic Diso

1987