Page last updated: 2024-10-25

diazepam and Agitation, Psychomotor

diazepam has been researched along with Agitation, Psychomotor in 32 studies

Diazepam: A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of GAMMA-AMINOBUTYRIC ACID activity.
diazepam : A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a chloro group at position 7, a methyl group at position 1 and a phenyl group at position 5.

Research Excerpts

ExcerptRelevanceReference
"In this study, we evaluated the effect of intrathecal and oral clonidine as supplements to spinal anesthesia with lidocaine in patients at risk of postoperative alcohol withdrawal syndrome (AWS)."5.11Intrathecal and oral clonidine as prophylaxis for postoperative alcohol withdrawal syndrome: a randomized double-blinded study. ( Axelsson, K; Berggren, L; Dobrydnjov, I; Holmström, B; Samarütel, J, 2004)
"The World Health Organization recommends that anxiety, depression, agitation and delirium at end of life should be treated with drugs such as lorazepam, diazepam, midazolam and haloperidol."3.83Look again at psychedelic drugs. ( Cameron, R, 2016)
" He developed neuroleptic malignant syndrome (NMS) which was treated successfully with intravenous diazepam."3.69Catatonic syndrome following recovery from neuroleptic malignant syndrome. ( Dent, J, 1995)
"Three children received 1000 times the prescribed dose of atropine sulphate and recovered from the main effects of excitatory behaviour and hallucinations in 48 hours."3.66Atropine--a safe drug. ( Arthurs, GJ; Davies, R, 1980)
" In all three cases, an increase in the anesthetic (or equivalent medication) dosage prior to ECT prevented the emergence of postictal excitement at subsequent treatments."2.67Use of increased anesthetic dose prior to electroconvulsive therapy to prevent postictal excitement. ( Devanand, DP; Sackeim, HA, 1992)
"Terminal restlessness is a variant of delirium observed in some patients in their last days of life."2.40Palliative care: an update on "terminal restlessness". ( Burke, AL, 1997)
"Before intratracheal suctioning, patients had RASS scores of -1."1.38Assessment of pain in sedated and mechanically ventilated patients: an observational study. ( Hamers, JP; Hantikainen, V; Jakob, SM; Jeitziner, MM; Rohrer, O; Schwendimann, R, 2012)
" Further, chronic administration of berberine (10 and 20 mg/kg, i."1.37Berberine protects C57BL/6J mice against ethanol withdrawal-induced hyperexcitability. ( Bansod, K; Bhutada, P; Dixit, P; Hiware, R; Mundhada, D; Mundhada, Y; Rathod, S, 2011)
"All four of the reviewed cases with myokymia of the shoulders were intubated and none without it were intubated."1.35Fasciculations after rattlesnake envenomations: a retrospective statewide poison control system study. ( Cantrell, FL; Vohra, R; Williams, SR, 2008)
"Pupils were dilated in 18 of the 19 and restlessness and hallucinations were present in 17."1.28[Henbane (Hyoscyamus reticulatus) poisoning in children in the Negev]. ( Shalev, H; Sofer, S; Urkin, J; Witztum, A, 1991)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199013 (40.63)18.7374
1990's7 (21.88)18.2507
2000's5 (15.63)29.6817
2010's7 (21.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, R1
Kailainathan, R1
Wong, A1
Greene, S1
Koutsogiannis, Z1
Auvin, S1
Lejay, E1
Delanoe, C1
Denjoy, I1
Lupoglazoff, JM1
Mercier, JC1
Titomanlio, L1
Bhutada, P1
Mundhada, Y1
Bansod, K1
Hiware, R1
Rathod, S1
Dixit, P1
Mundhada, D1
James, BO1
Jeitziner, MM1
Schwendimann, R1
Hamers, JP1
Rohrer, O1
Hantikainen, V1
Jakob, SM1
Ziv, L1
Muto, A1
Schoonheim, PJ1
Meijsing, SH1
Strasser, D1
Ingraham, HA1
Schaaf, MJ1
Yamamoto, KR1
Baier, H1
KRAUSE, G1
Dobrydnjov, I1
Axelsson, K1
Berggren, L1
Samarütel, J1
Holmström, B1
Duverger, P1
Picherot, G1
Champion, G1
Dreno, L1
Gold, JA1
Rimal, B1
Nolan, A1
Nelson, LS1
Vohra, R1
Cantrell, FL1
Williams, SR1
George, MS1
Sury, MR1
Boulard, G1
Bioulac, B1
Sabathié, M1
Saletu, B1
Grünberger, J1
Amrein, R1
Skreta, M1
Mikhaĭlenko, AA1
Beliakov, VA1
Sinitsyn, LN1
Kolpashchikova, IF1
Shidlovskiĭ, AS1
Arthurs, GJ1
Davies, R1
Baggio, P1
Fumiani, G1
Danda, R1
Smith, VM1
Dent, J1
Burke, AL1
Venturini, AH1
Parietti, A1
Giménez, JC1
Gagrat, D1
Hamilton, J1
Belmaker, RH1
Devanand, DP1
Sackeim, HA1
Urkin, J1
Shalev, H1
Sofer, S1
Witztum, A1
Lopez, A1
Rebollo, J1
Swartz, CM1
Hermesh, H1
Molcho, A1
Munitz, H1
Tasić, M1
Simić, M1
Radić, A1
Zivojnović, S1
Vujić, D1
Milam, SB1
Bennett, CR1
Dochy, M1
Ellison, JM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Smart Pain Assesment Tool Based on Internet of Things[NCT03061240]58 participants (Actual)Interventional2017-11-20Completed
Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464]Phase 4142 participants (Anticipated)Interventional2020-07-06Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for diazepam and Agitation, Psychomotor

ArticleYear
Palliative care: an update on "terminal restlessness".
    The Medical journal of Australia, 1997, Jan-06, Volume: 166, Issue:1

    Topics: Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Clonazepam; Delirium; Diazepam; Humans;

1997

Trials

5 trials available for diazepam and Agitation, Psychomotor

ArticleYear
Intrathecal and oral clonidine as prophylaxis for postoperative alcohol withdrawal syndrome: a randomized double-blinded study.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:3

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Aged; Alcoholism; Anesthesia; Central Nervous Syste

2004
Assessment of pharmacodynamics of a new "controlled release" form of diazepam (Valium CR Roche) by quantitative EEG and psychometric analysis in neurotic subjects.
    The Journal of international medical research, 1981, Volume: 9, Issue:6

    Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Diazepam; Double-Blind Method; Electro

1981
[Flunitrazepam (Ro 5-4200): a new benzodiazepinic derivative. Comparative double blind study with diazepam to control the psychomotor reactions of ketamine].
    Revista espanola de anestesiologia y reanimacion, 1977, Volume: 24, Issue:4

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Anti-Anxiety Agents; Diazepam; Dilatation and Cure

1977
Use of increased anesthetic dose prior to electroconvulsive therapy to prevent postictal excitement.
    General hospital psychiatry, 1992, Volume: 14, Issue:5

    Topics: Aged; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroconvulsive Thera

1992
Double blind comparative study with intrarectal administration of midazolam, intramuscular administration of diazepam and intrarectal administration of diazepam: preliminary results.
    Acta anaesthesiologica Belgica, 1987, Volume: 38, Issue:3 Suppl 1

    Topics: Administration, Rectal; Anxiety; Child; Child, Preschool; Diazepam; Double-Blind Method; Humans; Inf

1987

Other Studies

26 other studies available for diazepam and Agitation, Psychomotor

ArticleYear
Look again at psychedelic drugs.
    Nursing standard (Royal College of Nursing (Great Britain) : 1987), 2016, Jun-29, Volume: 30, Issue:44

    Topics: Anxiety; Delirium; Depression; Diazepam; Hallucinogens; Haloperidol; Humans; Lorazepam; Midazolam; P

2016
Recognition of gamma-hydroxybutyric acid withdrawal: Rapid progression and prolonged symptomatology.
    Emergency medicine Australasia : EMA, 2017, Volume: 29, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Australia; Baclofen; Benzodiazepines; Diazepam; Humans; Hydroxybutyrat

2017
Clinical reasoning: seizures in a child with sensorineural deafness and agitation.
    Neurology, 2010, Apr-13, Volume: 74, Issue:15

    Topics: Adrenergic beta-Antagonists; Anticonvulsants; Child, Preschool; Diazepam; Electroencephalography; Fe

2010
Berberine protects C57BL/6J mice against ethanol withdrawal-induced hyperexcitability.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:2

    Topics: Animals; Berberine; Diazepam; Ethanol; Male; Mice; Mice, Inbred C57BL; Motor Activity; Psychomotor A

2011
Rapid tranquillization agents for severe behavioural disturbance: a survey of African psychiatrists' prescription patterns.
    Tropical doctor, 2011, Volume: 41, Issue:1

    Topics: Africa; Chlorpromazine; Diazepam; Health Care Surveys; Humans; Mental Disorders; Practice Patterns,

2011
Assessment of pain in sedated and mechanically ventilated patients: an observational study.
    Acta anaesthesiologica Scandinavica, 2012, Volume: 56, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Analysis of Variance; Behavior; Cons

2012
An affective disorder in zebrafish with mutation of the glucocorticoid receptor.
    Molecular psychiatry, 2013, Volume: 18, Issue:6

    Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Anxiety Agents; Arginine; Brain;

2013
[RESTLESSNESS, COMPULSIONS, ANXIETY--STILL A THERAPEUTIC PROBLEM?].
    Therapie der Gegenwart, 1964, Volume: 103

    Topics: Anxiety; Anxiety Disorders; Chlordiazepoxide; Compulsive Behavior; Diazepam; Humans; Neurotic Disord

1964
[Turbulence in emergency ward. Agitation of children and adolescents].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2006, Volume: 13, Issue:6

    Topics: Acute Disease; Adolescent; Antipsychotic Agents; Child; Crisis Intervention; Diagnosis, Differential

2006
A strategy of escalating doses of benzodiazepines and phenobarbital administration reduces the need for mechanical ventilation in delirium tremens.
    Critical care medicine, 2007, Volume: 35, Issue:3

    Topics: Adult; Alcohol Withdrawal Delirium; Cohort Studies; Cross Infection; Diazepam; Dose-Response Relatio

2007
Fasciculations after rattlesnake envenomations: a retrospective statewide poison control system study.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Animals; Antivenins; Anxiety; California; Child; Child, Preschool; Crotalus; Data

2008
Reversal of paradoxical excitement to diazepam sedation.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:6

    Topics: Anti-Anxiety Agents; Antidotes; Child; Conscious Sedation; Diazepam; Flumazenil; Humans; Male; Psych

2008
[Psychomotor hyperexcitability induced by fentanyl in anesthesia].
    Annales francaises d'anesthesie et de reanimation, 1982, Volume: 1, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Anesthesia, Intravenous; Animals; Diazepam; Fentanyl; Humans; Male;

1982
[Use of sodium oxybutyrate and diazepam for removing the psychomotor excitation in hepatic coma].
    Anesteziologiia i reanimatologiia, 1980, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Cats; Diazepam; Drug Evaluation; Drug Evaluation, Preclinic

1980
Atropine--a safe drug.
    Anaesthesia, 1980, Volume: 35, Issue:11

    Topics: Akathisia, Drug-Induced; Atropine; Child; Diazepam; Hallucinations; Humans; Medication Errors; Prean

1980
[Tipepidine poisoning].
    Minerva pediatrica, 1980, Jun-30, Volume: 32, Issue:12

    Topics: Akathisia, Drug-Induced; Child, Preschool; Diazepam; Female; Humans; Medication Errors; Piperidines;

1980
Paradoxical reactions to diazepam.
    Gastrointestinal endoscopy, 1995, Volume: 41, Issue:2

    Topics: Conscious Sedation; Diazepam; Flumazenil; Humans; Psychomotor Agitation

1995
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
    Journal of intellectual disability research : JIDR, 1995, Volume: 39 ( Pt 5)

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relati

1995
Intravenous diazepam in the treatment of neuroleptic-induced acute dystonia and akathisia.
    The American journal of psychiatry, 1978, Volume: 135, Issue:10

    Topics: Acute Disease; Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Dyskinesia, Drug-Induced; Dy

1978
[Henbane (Hyoscyamus reticulatus) poisoning in children in the Negev].
    Harefuah, 1991, Jun-16, Volume: 120, Issue:12

    Topics: Child; Child, Preschool; Coma; Diazepam; Hallucinations; Humans; Hypnotics and Sedatives; Organophos

1991
Benzodiazepine withdrawal syndrome after a benzodiazepine antagonist.
    Critical care medicine, 1990, Volume: 18, Issue:12

    Topics: Adolescent; Akathisia, Drug-Induced; Diazepam; Drug Overdose; Flumazenil; Humans; Injections, Intrav

1990
Electroconvulsive therapy emergence agitation and succinylcholine dose.
    The Journal of nervous and mental disease, 1990, Volume: 178, Issue:7

    Topics: Adult; Akathisia, Drug-Induced; Bipolar Disorder; Depressive Disorder; Diazepam; Dose-Response Relat

1990
Successful propranolol therapy for neuroleptic-induced akathisia resistant to anticholinergic and benzodiazepine drugs.
    Clinical neuropharmacology, 1988, Volume: 11, Issue:4

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Diazepam; Female; Humans; Male; Propranolol; P

1988
Fatal central effects of diazepam potentiated by alcohol and haldol.
    Acta medicinae legalis et socialis, 1985, Volume: 35, Issue:1

    Topics: Alcoholic Intoxication; Diazepam; Drug Synergism; Drug Therapy, Combination; Ethanol; Haloperidol; H

1985
Physostigmine reversal of drug-induced paradoxical excitement.
    International journal of oral and maxillofacial surgery, 1987, Volume: 16, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Anesthesia, Dental; Cooperative Behavior; Diazepam; Female; Fentanyl

1987
Emergency treatment of acute psychosis, agitation, and anxiety.
    Hospital & community psychiatry, 1985, Volume: 36, Issue:4

    Topics: Anxiety Disorders; Diazepam; Droperidol; Emergencies; Haloperidol; Humans; Lorazepam; Panic; Propran

1985