diacetylmonoxime and Organophosphate-Poisoning

diacetylmonoxime has been researched along with Organophosphate-Poisoning* in 2 studies

Other Studies

2 other study(ies) available for diacetylmonoxime and Organophosphate-Poisoning

Article	Year
Pyridine-2-aldoxime methiodide and diacetyl monoxime against organophosphorus poisoning. Science (New York, N.Y.), 1958, Nov-07, Volume: 128, Issue:3332 Topics: Diacetyl; Drug-Related Side Effects and Adverse Reactions; Hydroxylamines; Organophosphate Poisoning; Phosphates; Pralidoxime Compounds; Pyridines	1958
Oximes and atropine in sarin poisoning. British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:3 Three oximes, monoisonitrosoacetone (MINA), pyridine-2-aldoxime methiodide (PAM) and diacetylmonoxime (DAM), have been examined in combination with atropine as antidotes in sarin poisoning. When treatment was administered 15 min. before sarin, atropine enhanced the protective effect of MINA and DAM 2 to 3 times and of PAM 9 to 10 times in mice and rats. In mice, rats, and guinea-pigs, atropine increased by no more than 2 times the protective effect of all three oximes when given 30 sec. after sarin. Atropine given to monkeys 1 min. after sarin raised the LD50 approximately 3 times. When given in conjunction with MINA or DAM, the LD50 of sarin was raised 7 to 14 times. Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diacetyl; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Hydroxylamines; Mice; Organophosphate Poisoning; Oximes; Phosphates; Pralidoxime Compounds; Rats; Sarin	1957

Article

Year

Pyridine-2-aldoxime methiodide and diacetyl monoxime against organophosphorus poisoning.

Science (New York, N.Y.), 1958, Nov-07, Volume: 128, Issue:3332

Topics: Diacetyl; Drug-Related Side Effects and Adverse Reactions; Hydroxylamines; Organophosphate Poisoning; Phosphates; Pralidoxime Compounds; Pyridines

1958

Oximes and atropine in sarin poisoning.

British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:3

Three oximes, monoisonitrosoacetone (MINA), pyridine-2-aldoxime methiodide (PAM) and diacetylmonoxime (DAM), have been examined in combination with atropine as antidotes in sarin poisoning. When treatment was administered 15 min. before sarin, atropine enhanced the protective effect of MINA and DAM 2 to 3 times and of PAM 9 to 10 times in mice and rats. In mice, rats, and guinea-pigs, atropine increased by no more than 2 times the protective effect of all three oximes when given 30 sec. after sarin. Atropine given to monkeys 1 min. after sarin raised the LD50 approximately 3 times. When given in conjunction with MINA or DAM, the LD50 of sarin was raised 7 to 14 times.

Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diacetyl; Drug-Related Side Effects and Adverse Reactions; Guinea Pigs; Hydroxylamines; Mice; Organophosphate Poisoning; Oximes; Phosphates; Pralidoxime Compounds; Rats; Sarin

1957