diacetyl has been researched along with Pulmonary Fibrosis in 2 studies
butane-2,3-dione : An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diacetyl (DA), a component of artificial butter flavoring, has been linked to the development of bronchiolitis obliterans (BO), a disease of airway epithelial injury and airway fibrosis." | 7.80 | Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans. ( Beasley, RF; Fischer, BM; Gwinn, WM; Kelly, FL; Kummarapurugu, AB; Martinu, T; Morgan, DL; Nugent, JL; Palmer, SM; Sun, J; Voynow, JA; Zhang, HL, 2014) |
| "Diacetyl (DA), a component of artificial butter flavoring, has been linked to the development of bronchiolitis obliterans (BO), a disease of airway epithelial injury and airway fibrosis." | 3.80 | Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans. ( Beasley, RF; Fischer, BM; Gwinn, WM; Kelly, FL; Kummarapurugu, AB; Martinu, T; Morgan, DL; Nugent, JL; Palmer, SM; Sun, J; Voynow, JA; Zhang, HL, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kelly, FL | 2 |
| Sun, J | 1 |
| Fischer, BM | 1 |
| Voynow, JA | 1 |
| Kummarapurugu, AB | 1 |
| Zhang, HL | 2 |
| Nugent, JL | 2 |
| Beasley, RF | 1 |
| Martinu, T | 1 |
| Gwinn, WM | 2 |
| Morgan, DL | 2 |
| Palmer, SM | 2 |
| Flake, GP | 1 |
| Kirby, PJ | 1 |
| Foley, JF | 1 |
2 other studies available for diacetyl and Pulmonary Fibrosis
| Article | Year |
|---|---|
Diacetyl induces amphiregulin shedding in pulmonary epithelial cells and in experimental bronchiolitis obliterans.
Topics: ADAM Proteins; ADAM17 Protein; Amphiregulin; Bronchiolitis Obliterans; Cell Line; Diacetyl; Dose-Res | 2014 |
Severe airway epithelial injury, aberrant repair and bronchiolitis obliterans develops after diacetyl instillation in rats.
Topics: Animals; Bronchiolitis Obliterans; Cell Proliferation; Diacetyl; Disease Progression; Epithelial Cel | 2011 |