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diacetyl and Disease Models, Animal

diacetyl has been researched along with Disease Models, Animal in 19 studies

butane-2,3-dione : An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Whether or not the excitation-contraction (E-C) uncoupler diacetyl monoxime (DAM) and cytochalacin D (Cyto D) alter the ventricular fibrillation (VF) activation patterns is unclear."7.71Effects of diacetyl monoxime and cytochalasin D on ventricular fibrillation in swine right ventricles. ( Chen, PS; Chudin, E; Garfinkel, A; Karagueuzian, HS; Lee, MH; Lin, SF; Ohara, T; Okuyama, Y; Omichi, C; Weiss, JN, 2001)
"Diacetyl and 2,3-pentanedione inhalation have been suggested as causes of severe respiratory disease, including bronchiolitis obliterans, in food/flavoring manufacturing workers."4.90Diacetyl and 2,3-pentanedione exposures associated with cigarette smoking: implications for risk assessment of food and flavoring workers. ( Abelmann, A; Adams, RE; Finley, BL; Pierce, JS; Spicer, LJ, 2014)
"Whether or not the excitation-contraction (E-C) uncoupler diacetyl monoxime (DAM) and cytochalacin D (Cyto D) alter the ventricular fibrillation (VF) activation patterns is unclear."3.71Effects of diacetyl monoxime and cytochalasin D on ventricular fibrillation in swine right ventricles. ( Chen, PS; Chudin, E; Garfinkel, A; Karagueuzian, HS; Lee, MH; Lin, SF; Ohara, T; Okuyama, Y; Omichi, C; Weiss, JN, 2001)
"After 16minutes of untreated ventricular fibrillation and 8minutes of basic life support, 36 pigs were divided randomly into 3 groups that received 50mg/kg (low-dose group) of BDM, 100mg/kg (high-dose group) of BDM, or an equivalent volume of saline (control group) during advanced cardiovascular life support."1.432,3-Butanedione monoxime facilitates successful resuscitation in a dose-dependent fashion in a pig model of cardiac arrest. ( Choi, SS; Jeung, KW; Kim, MJ; Lee, BK; Lee, DH; Lee, SM; Min, YI; Park, SW; Yun, SW, 2016)
"The susceptibility to arrhythmia was investigated using a shock-on-T protocol."1.38The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime. ( Efimov, IR; Li, W; Lou, Q, 2012)
"An important mechanism of lethal myocardial reperfusion injury is the development of cellular hypercontracture at the onset of reperfusion."1.29Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart. ( Bier, F; Piper, HM; Schäfer, M; Schäfer, S; Schlack, W; Thämer, V; Uebing, A, 1994)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's2 (10.53)18.2507
2000's5 (26.32)29.6817
2010's9 (47.37)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH2
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W2
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Kato, M1
Yamaguchi, M1
Ooka, A1
Takahashi, R1
Suzuki, T1
Onoda, K1
Yoshikawa, Y1
Tsunematsu, Y1
Sato, M1
Yoshioka, Y1
Igarashi, M1
Hayakawa, S1
Shoji, K1
Shoji, Y1
Ishikawa, T1
Watanabe, K1
Miyoshi, N1
Pierce, JS1
Abelmann, A1
Spicer, LJ1
Adams, RE1
Finley, BL1
Lee, BK2
Jeung, KW2
Choi, SS2
Park, SW2
Yun, SW2
Lee, SM2
Kim, NY1
Heo, T1
Min, YI2
Kim, MJ1
Lee, DH1
Kreiss, K1
Flake, GP1
Morgan, DL1
Flagg, TP1
Cazorla, O1
Remedi, MS1
Haim, TE1
Tones, MA1
Bahinski, A1
Numann, RE1
Kovacs, A1
Schaffer, JE1
Nichols, CG1
Nerbonne, JM1
Taysse, L1
Dorandeu, F1
Daulon, S1
Foquin, A1
Perrier, N1
Lallement, G1
Breton, P1
Lou, Q1
Efimov, IR1
Sumita Yoshikawa, W1
Nakamura, K1
Miura, D1
Shimizu, J1
Hashimoto, K1
Kataoka, N1
Toyota, H1
Okuyama, H1
Miyoshi, T1
Morita, H1
Fukushima Kusano, K1
Matsuo, T1
Takaki, M1
Kajiya, F1
Yagi, N1
Ohe, T1
Ito, H1
Wang, X1
Guan, XM1
Li, GP1
Ren, Y1
Drzewiecki, G1
Li, JK1
Kedem, J1
Iorga, B1
Blaudeck, N1
Solzin, J1
Neulen, A1
Stehle, I1
Lopez Davila, AJ1
Pfitzer, G1
Stehle, R1
Cartier, R1
Carrier, M1
Buluran, J1
Millette, D1
Dagenais, F1
Schlack, W1
Uebing, A1
Schäfer, M1
Bier, F1
Schäfer, S1
Piper, HM1
Thämer, V1
Su, Z1
Yao, A1
Zubair, I1
Sugishita, K1
Ritter, M1
Li, F1
Hunter, JJ1
Chien, KR1
Barry, WH1
Lin, SF1
Ohara, T1
Omichi, C1
Okuyama, Y1
Chudin, E1
Garfinkel, A1
Weiss, JN1
Karagueuzian, HS1
Chen, PS1
Rubin, IB1
Gill, BE1
Guerin, MR1
Kendrick, J1
Nettesheim, P1

Reviews

1 review available for diacetyl and Disease Models, Animal

ArticleYear
Diacetyl and 2,3-pentanedione exposures associated with cigarette smoking: implications for risk assessment of food and flavoring workers.
    Critical reviews in toxicology, 2014, Volume: 44, Issue:5

    Topics: Animals; Bronchiolitis Obliterans; Canada; Diacetyl; Disease Models, Animal; Evaluation Studies as T

2014

Other Studies

18 other studies available for diacetyl and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Non-target GC-MS analyses of fecal VOCs in NASH-hepatocellular carcinoma model STAM mice.
    Scientific reports, 2023, 06-01, Volume: 13, Issue:1

    Topics: Animals; Biomarkers; Carcinogenesis; Carcinoma, Hepatocellular; Diacetyl; Disease Models, Animal; Fi

2023
Effects of the administration of 2,3-butanedione monoxime during conventional cardiopulmonary resuscitation on ischaemic contracture and resuscitability in a pig model of out-of-hospital cardiac arrest.
    Resuscitation, 2015, Volume: 87

    Topics: Advanced Cardiac Life Support; Animals; Diacetyl; Disease Models, Animal; Drug Monitoring; Enzyme In

2015
2,3-Butanedione monoxime facilitates successful resuscitation in a dose-dependent fashion in a pig model of cardiac arrest.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:6

    Topics: Animals; Cardiopulmonary Resuscitation; Diacetyl; Disease Models, Animal; Dose-Response Relationship

2016
Recognizing occupational effects of diacetyl: What can we learn from this history?
    Toxicology, 2017, 08-01, Volume: 388

    Topics: Animals; Bronchiolitis Obliterans; Cooperative Behavior; Diacetyl; Disease Models, Animal; Flavoring

2017
Pathology of diacetyl and 2,3-pentanedione airway lesions in a rat model of obliterative bronchiolitis.
    Toxicology, 2017, 08-01, Volume: 388

    Topics: Animals; Basement Membrane; Bronchiolitis Obliterans; Diacetyl; Disease Models, Animal; Flavoring Ag

2017
Ca2+-independent alterations in diastolic sarcomere length and relaxation kinetics in a mouse model of lipotoxic diabetic cardiomyopathy.
    Circulation research, 2009, Jan-02, Volume: 104, Issue:1

    Topics: Animals; Calcium; Chelating Agents; Diabetes Complications; Diacetyl; Diastole; Disease Models, Anim

2009
Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse (II): effects of some currently used skin decontaminants (RSDL and Fuller's earth) against liquid sulphur mustard and VX exposure.
    Human & experimental toxicology, 2011, Volume: 30, Issue:6

    Topics: Aluminum Compounds; Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Decontamination; Di

2011
The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime.
    American journal of physiology. Heart and circulatory physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial

2012
Increased passive stiffness of cardiomyocytes in the transverse direction and residual actin and myosin cross-bridge formation in hypertrophied rat hearts induced by chronic β-adrenergic stimulation.
    Circulation journal : official journal of the Japanese Circulation Society, 2013, Volume: 77, Issue:3

    Topics: Actins; Adrenergic beta-Agonists; Animals; Cardiomegaly; Cells, Cultured; Diacetyl; Disease Models,

2013
Characteristic dysfunction of stunned myocardium induced by 2,3-butanedione monoxime without ischaemia.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:11

    Topics: Acetylcholine; Animals; Coronary Circulation; Diacetyl; Disease Models, Animal; Dogs; Female; Hemody

2005
Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils.
    Cardiovascular research, 2008, Mar-01, Volume: 77, Issue:4

    Topics: Animals; Calcium Signaling; Cardiomyopathy, Hypertrophic, Familial; Diacetyl; Disease Models, Animal

2008
2,3-Butanedione monoxime preserves coronary artery endothelium-dependent relaxation during myocardial ischemia in the isolated rat heart.
    The Canadian journal of cardiology, 1995, Volume: 11, Issue:6

    Topics: Animals; Coronary Vessels; Diacetyl; Disease Models, Animal; Drug Evaluation, Preclinical; Myocardia

1995
Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart.
    Pflugers Archiv : European journal of physiology, 1994, Volume: 428, Issue:2

    Topics: Animals; Coronary Circulation; Diacetyl; Disease Models, Animal; Dogs; Female; Heart Rate; Infusions

1994
Effects of deletion of muscle LIM protein on myocyte function.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Actin Cytoskeleton; Animals; Body Weight; Calcium; Calcium Channels, L-Type; Cardiomyopathy, Dilated

2001
Effects of diacetyl monoxime and cytochalasin D on ventricular fibrillation in swine right ventricles.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:6

    Topics: Action Potentials; Animals; Cardiac Pacing, Artificial; Cytochalasin D; Diacetyl; Disease Models, An

2001
Correlation of respiratory parameters in hamsters with the lung deposition of radiolabeled cigarette smoke.
    Environmental research, 1978, Volume: 16, Issue:1-3

    Topics: Animals; Cricetinae; Diacetyl; Disease Models, Animal; Lung; Lung Volume Measurements; Male; Mesocri

1978