diacetyl has been researched along with Disease, Pulmonary in 13 studies
butane-2,3-dione : An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inhalation of diacetyl-containing products is associated with risk for occupational bronchiolitis obliterans (BO) and fixed airways obstruction, particularly in workers exposed to heated liquids and powdered formulations." | 4.95 | Early detection, clinical diagnosis, and management of lung disease from exposure to diacetyl. ( Rose, CS, 2017) |
| "Diacetyl substitutes cause similar peri-bronchiolar fibrotic lesions in animal studies." | 2.53 | Update on flavoring-induced lung disease. ( Hines, SE; Holden, VK, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (92.31) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Hubbs, AF | 2 |
| Kreiss, K | 4 |
| Cummings, KJ | 2 |
| Fluharty, KL | 2 |
| O'Connell, R | 1 |
| Cole, A | 1 |
| Dodd, TM | 1 |
| Clingerman, SM | 1 |
| Flesher, JR | 1 |
| Lee, R | 1 |
| Pagel, S | 1 |
| Battelli, LA | 2 |
| Cumpston, A | 1 |
| Jackson, M | 1 |
| Kashon, M | 1 |
| Orandle, MS | 1 |
| Fedan, JS | 2 |
| Sriram, K | 2 |
| Harvey, RR | 1 |
| Blackley, BH | 1 |
| Korbach, EJ | 1 |
| Rawal, AX | 1 |
| Roggli, VL | 1 |
| Bailey, RL | 1 |
| Cox-Ganser, JM | 1 |
| Rose, CS | 1 |
| Wallace, KB | 1 |
| Galbraith, DA | 1 |
| Holden, VK | 1 |
| Hines, SE | 1 |
| Edwards, RJ | 1 |
| Barnabei, JL | 1 |
| Grantham, JT | 1 |
| Palmer, SM | 3 |
| Kelly, F | 1 |
| Sargent, LM | 1 |
| Reynolds, SH | 1 |
| Mercer, RR | 1 |
| Goravanahally, MP | 1 |
| Kashon, ML | 1 |
| Honaker, JC | 1 |
| Jackson, MC | 1 |
| Cumpston, AM | 1 |
| Goldsmith, WT | 1 |
| McKinney, W | 1 |
| Munro, T | 1 |
| Bucklew-Moyers, W | 1 |
| McKinstry, K | 1 |
| Schwegler-Berry, D | 1 |
| Friend, S | 1 |
| Knepp, AK | 1 |
| Smith, SL | 1 |
| Brass, DM | 2 |
| Gwinn, WM | 1 |
| Valente, AM | 1 |
| Kelly, FL | 1 |
| Brinkley, CD | 1 |
| Nagler, AE | 1 |
| Moseley, MA | 1 |
| Morgan, DL | 1 |
| Foster, MW | 1 |
| Kim, TJ | 1 |
| Materna, BL | 1 |
| Prudhomme, JC | 1 |
| Fedan, KB | 1 |
| Enright, PL | 2 |
| Sahakian, NM | 1 |
| Windham, GC | 1 |
| Chaisson, NF | 1 |
| Hnizdo, E | 1 |
| Hakobyan, A | 1 |
| Sauler, M | 1 |
| Gulati, M | 1 |
5 reviews available for diacetyl and Disease, Pulmonary
| Article | Year |
|---|---|
Flavorings-Related Lung Disease: A Brief Review and New Mechanistic Data.
Topics: Acetoin; Air Pollutants, Occupational; Bronchiolitis Obliterans; Diacetyl; Flavoring Agents; Humans; | 2019 |
Early detection, clinical diagnosis, and management of lung disease from exposure to diacetyl.
Topics: Bronchiolitis Obliterans; Diacetyl; Flavoring Agents; Humans; Inhalation Exposure; Lung Diseases; Oc | 2017 |
Update on flavoring-induced lung disease.
Topics: Animals; Diacetyl; Flavoring Agents; Humans; Lung Diseases; Pentanones; Risk | 2016 |
Models of toxicity of diacetyl and alternative diones.
Topics: Animals; Diacetyl; Flavoring Agents; Humans; Inhalation Exposure; Lung Diseases; Occupational Diseas | 2017 |
Newly recognized occupational and environmental causes of chronic terminal airways and parenchymal lung disease.
Topics: Chronic Disease; Diacetyl; Environmental Exposure; Humans; Indium; Lung Diseases; Lung Diseases, Int | 2012 |
8 other studies available for diacetyl and Disease, Pulmonary
| Article | Year |
|---|---|
Case Report: Flavoring-Related Lung Disease in a Coffee Roasting and Packaging Facility Worker With Unique Lung Histopathology Compared With Previously Described Cases of Obliterative Bronchiolitis.
Topics: Adult; Bronchiolitis Obliterans; Coffee; Diacetyl; Humans; Lung; Lung Diseases; Male | 2021 |
Future perspective of butter flavorings-related occupational lung disease.
Topics: Butter; Diacetyl; Flavoring Agents; Humans; Lung Diseases; Occupational Diseases; Phenylbutazone | 2017 |
Diacetyl and occupational bronchiolitis obliterans: Comments on Rose, CS: Early detection, clinical diagnosis and management of lung disease from exposure to diacetyl, toxicology (2017), https://doi.org/10.1016/j.tox.2017.03.019.
Topics: Bronchiolitis Obliterans; Diacetyl; Humans; Lung Diseases; Occupational Diseases; Occupational Expos | 2017 |
Recognizing occupational effects of diacetyl: What can we learn from this history?
Topics: Animals; Bronchiolitis Obliterans; Cooperative Behavior; Diacetyl; Disease Models, Animal; Flavoring | 2017 |
Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity.
Topics: Animals; Autophagy; Diacetyl; Epithelial Cells; Flavoring Agents; Humans; Inhalation Exposure; Lung | 2016 |
The Diacetyl-Exposed Human Airway Epithelial Secretome: New Insights into Flavoring-Induced Airways Disease.
Topics: Cell Differentiation; Diacetyl; Epithelial Cells; ErbB Receptors; Extracellular Matrix; Flavoring Ag | 2017 |
Industry-wide medical surveillance of California flavor manufacturing workers: Cross-sectional results.
Topics: Adult; Bronchiolitis Obliterans; California; Cross-Sectional Studies; Diacetyl; Female; Flavoring Ag | 2010 |
Evaluation of methods to determine excessive decline of forced expiratory volume in one second in workers exposed to diacetyl-containing flavorings.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arizona; Cohort Studies; Diacetyl; Disease Progression; | 2010 |