Page last updated: 2024-10-18

diacetyl and Arrhythmias, Cardiac

diacetyl has been researched along with Arrhythmias, Cardiac in 8 studies

butane-2,3-dione : An alpha-diketone that is butane substituted by oxo groups at positions 2 and 3. It is a metabolite produced during the malolactic fermentation.

Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.

Research Excerpts

ExcerptRelevanceReference
"Chemical uncouplers diacetyl monoxime (DAM) and cytochalasin D (cyto-D) are used to abolish cardiac contractions in optical studies, yet alter intracellular Ca(2+) concentration ([Ca(2+)](i)) handling and vulnerability to arrhythmias in a species-dependent manner."3.72Effects of mechanical uncouplers, diacetyl monoxime, and cytochalasin-D on the electrophysiology of perfused mouse hearts. ( Baker, LC; Choi, BR; Plan, P; Salama, G; Shah, A; Watkins, S; Wolk, R, 2004)
"The susceptibility to arrhythmia was investigated using a shock-on-T protocol."1.38The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime. ( Efimov, IR; Li, W; Lou, Q, 2012)
"To determine why lethal arrhythmias are prone to occur in diseased hearts, usually characterized by nonuniform muscle contraction, we investigated the effect of nonuniformity on sustainability and frequency of triggered arrhythmias."1.36Effect of nonuniform muscle contraction on sustainability and frequency of triggered arrhythmias in rat cardiac muscle. ( Boyden, PA; Hattori, T; Miura, M; Murai, N; Nishio, T; Shindoh, C; Stuyvers, BD, 2010)
"Investigation of the mechanisms of arrhythmia genesis and maintenance has benefited from the use of optical mapping techniques that employ excitation-contraction uncouplers."1.32Shock-induced arrhythmogenesis is enhanced by 2,3-butanedione monoxime compared with cytochalasin D. ( Cheng, Y; Efimov, IR; Li, L; Nikolski, V; Wallick, DW, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miura, M3
Wakayama, Y2
Endoh, H1
Nakano, M1
Sugai, Y1
Hirose, M1
Ter Keurs, HE2
Shimokawa, H1
Nishio, T1
Hattori, T1
Murai, N1
Stuyvers, BD2
Shindoh, C1
Boyden, PA2
Lou, Q1
Li, W1
Efimov, IR2
Cheng, Y1
Li, L1
Nikolski, V1
Wallick, DW1
Baker, LC1
Wolk, R1
Choi, BR1
Watkins, S1
Plan, P1
Shah, A1
Salama, G1
Kawai, M1
Lee, JA1
Orchard, CH1
Maesako, M1
Araki, J1
Lee, S1
Doi, Y1
Imaoka, T1
Iribe, G1
Mohri, S1
Hirakawa, M1
Harada, M1
Suga, H1

Other Studies

8 other studies available for diacetyl and Arrhythmias, Cardiac

ArticleYear
Spatial non-uniformity of excitation-contraction coupling can enhance arrhythmogenic-delayed afterdepolarizations in rat cardiac muscle.
    Cardiovascular research, 2008, Oct-01, Volume: 80, Issue:1

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Diacetyl; In Vitro Techniques; Mem

2008
Effect of nonuniform muscle contraction on sustainability and frequency of triggered arrhythmias in rat cardiac muscle.
    Circulation, 2010, Jun-29, Volume: 121, Issue:25

    Topics: Actin Cytoskeleton; Animals; Arrhythmias, Cardiac; Calcium Signaling; Diacetyl; Heart; Heart Ventric

2010
The role of dynamic instability and wavelength in arrhythmia maintenance as revealed by panoramic imaging with blebbistatin vs. 2,3-butanedione monoxime.
    American journal of physiology. Heart and circulatory physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial

2012
Shock-induced arrhythmogenesis is enhanced by 2,3-butanedione monoxime compared with cytochalasin D.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 286, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cytochalasin D; Diacetyl; Electroshock; In Vitro T

2004
Effects of mechanical uncouplers, diacetyl monoxime, and cytochalasin-D on the electrophysiology of perfused mouse hearts.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:4

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Cytochalasin D; Diacetyl; Electrophysiolo

2004
Spatial nonuniformity of excitation-contraction coupling causes arrhythmogenic Ca2+ waves in rat cardiac muscle.
    Circulation research, 2005, Jun-24, Volume: 96, Issue:12

    Topics: Animals; Arrhythmias, Cardiac; Caffeine; Calcium; Diacetyl; Heart; Myocardial Contraction; Myocytes,

2005
Effects of the Ca2+ sensitizer EMD 57033 on intracellular Ca2+ in rat ventricular myocytes: relevance to arrhythmogenesis during positive inotropy.
    Clinical science (London, England : 1979), 2000, Volume: 99, Issue:6

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium-Binding Proteins; Cardiotonic Agents; Diacetyl; Dose

2000
2,3-Butanedione monoxime suppresses primarily total calcium handling in canine heart.
    The Japanese journal of physiology, 2000, Volume: 50, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Diacetyl; Dogs; Enzyme Inhibitors; In Vitro Techniques; Myoc

2000