diacerein has been researched along with Osteoarthritis, Knee in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.33) | 18.2507 |
| 2000's | 14 (46.67) | 29.6817 |
| 2010's | 10 (33.33) | 24.3611 |
| 2020's | 5 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Fang, W; He, K; Shi, WX; Wang, F | 1 |
| Aitken, D; Antony, B; Buttigieg, K; Cai, G; Cicuttini, FM; de Graaff, B; Hill, C; Jones, G; Keen, H; Thompson, M; Wang, X; Wang, Y; Winzenberg, T; Wluka, AE | 1 |
| Alekseeva, LI; Amirdzhanova, VN; Filatova, ES; Karateev, AE; Lila, AM; Nesterenko, VA; Pogozheva, EY | 1 |
| Lai, Y; Li, G; Li, H; Luo, H; Tang, K; Ye, Y; Zhang, Z | 1 |
| Bessette, L; Dokoupilova, E; Dorais, M; Martel-Pelletier, J; Morin, F; Paiement, P; Pavelka, K; Pelletier, JP; Raynauld, JP | 1 |
| Bolliger Neto, R; Hernandez, AJ; Oliveira, CR; Rezende, MU | 1 |
| Anothaisintawee, T; Attia, J; Kongtharvonskul, J; McEvoy, M; Thakkinstian, A; Woratanarat, P | 1 |
| Agievich, TB; Bushina, AV; Gelmutdinov, DD; Kovalskaya, LP; Markina, OI; Slutskaya, NP; Voronina, NV | 1 |
| Filardo, G; Kon, E; Longo, UG; Madry, H; Marchettini, P; Marmotti, A; Peretti, GM; Van Assche, D; Zanon, G | 1 |
| Nikitin, AV; Starodubtseva, IA; Vasilieva, LV | 1 |
| Attia, J; Kawinwonggowit, V; Kongtharvonskul, J; McEvoy, M; Thakkinstian, A; Wongsak, S; Woratanarat, P | 1 |
| Baliga, VP; Rathod, R; Sharma, A | 1 |
| Brahmachari, B; Chatterjee, S; Ghosh, A | 1 |
| Altman, RD; Bartels, EM; Bliddal, H; Christensen, R; Schøndorff, PK; Zhang, W | 1 |
| Rai, J; Sharma, R; Singh, K | 1 |
| Qi, JM; Wang, FS; Wu, QF | 1 |
| Abadie, E; Avouac, B; Bouvenot, G; Branco, J; Bruyere, O; Calvo, G; Devogelaer, JP; Dreiser, RL; Ethgen, D; Herrero-Beaumont, G; Kahan, A; Kreutz, G; Laslop, A; Lemmel, EM; Nuki, G; Reginster, JY; Van De Putte, L; Vanhaelst, L | 1 |
| Dieppe, P; Dougados, M; Le Henanff, A; Paolozzi, L; Pham, T; Ravaud, P | 1 |
| Huang, F; Li, J; Li, ZG; Liang, DF; Ma, L; Su, Y; Tang, FL; Wu, DH; Xu, H; Zhang, FC; Zhang, JL; Zheng, WJ; Zhou, HQ; Zhou, YX | 1 |
| Leeb, BF; Neumann, K; Rintelen, B | 1 |
| Gurgel, HM; Hernandez, AJ; Kuroba, RK; Lopes, AS; Phillipi, RZ; Rezende, MU; Vilaça Junior, PR | 1 |
| Aksaranugraha, S; Asavatanabodee, P; Louthrenoo, W; Nilganuwong, S; Saengnipanthkul, S | 1 |
| Böhmová, J; Karpas, K; Pavelka, K; Rovenský, J; Sedlácková, M; Trc, T; Vítek, P; Vlasáková, V | 1 |
| Alvarez-Soria, MA; Bellido, M; Herrero-Beaumont, G; Largo, R; Sánchez-Pernaute, O | 1 |
| Berdah, L; Gérentes, I; Lequesne, M | 1 |
| Beaulieu, AD; Choquette, D; Cohen, P; Haraoui, B; Nahir, MA; Pelletier, JP; Rosner, IA; Wigler, I; Yaron, M | 1 |
| Chantre, P; Fournié, B; Leblan, D | 1 |
| Cappelaere, A; Chantre, P; Fournie, B; Guedon, D; Leblan, D; Vandermander, J | 1 |
| Dougados, M; Hochberg, MC | 1 |
7 review(s) available for diacerein and Osteoarthritis, Knee
| Article | Year |
|---|---|
Efficacy, residual effectiveness and safety of diacerein in the treatment of knee osteoarthritis: A meta-analysis of randomized placebo-controlled trials.
Topics: Aged; Anthraquinones; Diarrhea; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Humans; Osteoarthritis, Knee; Randomized Controlled Trials as Topic | 2022 |
Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis.
Topics: Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Glucosamine; Humans; Osteoarthritis, Knee | 2015 |
Non-surgical treatments for the management of early osteoarthritis.
Topics: Adrenal Cortex Hormones; Analgesics; Anthraquinones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Chondroitin Sulfates; Early Medical Intervention; Exercise Therapy; Glucosamine; Humans; Hyaluronic Acid; Injections, Intra-Articular; Osteoarthritis, Knee; Physical Therapy Modalities; Viscosupplementation; Viscosupplements | 2016 |
Symptomatic efficacy and safety of diacerein in the treatment of osteoarthritis: a meta-analysis of randomized placebo-controlled trials.
Topics: Anthraquinones; Anti-Inflammatory Agents; Humans; Osteoarthritis, Hip; Osteoarthritis, Knee; Placebos; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Recommendations for the use of new methods to assess the efficacy of disease-modifying drugs in the treatment of osteoarthritis.
Topics: Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cartilage, Articular; Disease Progression; Glucosamine; Humans; Interleukin-1; Joints; Magnetic Resonance Imaging; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Radiography; Treatment Outcome | 2004 |
A meta-analysis of controlled clinical studies with diacerein in the treatment of osteoarthritis.
Topics: Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Humans; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Randomized Controlled Trials as Topic; Treatment Outcome | 2006 |
Pharmacological therapy of osteoarthritis.
Topics: Acetaminophen; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chondroitin Sulfates; Glucosamine; Humans; Meta-Analysis as Topic; Osteoarthritis, Hip; Osteoarthritis, Knee | 2001 |
16 trial(s) available for diacerein and Osteoarthritis, Knee
| Article | Year |
|---|---|
Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS).
Topics: Anthraquinones; Australia; Humans; Multicenter Studies as Topic; Osteoarthritis, Knee; Pain; Randomized Controlled Trials as Topic; Synovitis; Treatment Outcome | 2022 |
An international, multicentre, double-blind, randomized study (DISSCO): effect of diacerein vs celecoxib on symptoms in knee osteoarthritis.
Topics: Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Celecoxib; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement | 2020 |
[Treatment for knee osteoarthritis in patients with oxalate nephropathy].
Topics: Anthraquinones; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Injections, Intramuscular; Kidney Calculi; Middle Aged; Osteoarthritis, Knee; Oxalates; Treatment Outcome | 2015 |
Efficacy of glucosamine plus diacerein versus monotherapy of glucosamine: a double-blind, parallel randomized clinical trial.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents; Double-Blind Method; Drug Therapy, Combination; Female; Glucosamine; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Treatment Outcome | 2016 |
An open prospective study on postmarketing evaluation of the efficacy and tolerability of diacerein in osteo-arthritis of the knee (DOK).
Topics: Administration, Oral; Adult; Aged; Anthraquinones; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Product Surveillance, Postmarketing; Prospective Studies; Treatment Outcome | 2008 |
Efficacy and safety of diacerein in early knee osteoarthritis: a randomized placebo-controlled trial.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents; Disability Evaluation; Dose-Response Relationship, Drug; Drug Tolerance; Female; Follow-Up Studies; Humans; India; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Patient Compliance; Product Surveillance, Postmarketing; Severity of Illness Index; Single-Blind Method; Treatment Outcome | 2009 |
Diacerein as adjuvant to diclofenac sodium in osteoarthritis knee.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anthraquinones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Capsules; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; India; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Placebos; Prospective Studies; Range of Motion, Articular; Recovery of Function; Surveys and Questionnaires; Time Factors; Treatment Outcome | 2012 |
[Clinical study of Qianggu granule and diacerein capsule in treating knee osteoarthritis].
Topics: Adult; Anthraquinones; Blood Sedimentation; C-Reactive Protein; Capsules; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Phytotherapy; Tumor Necrosis Factor-alpha | 2012 |
Evaluation of the symptomatic and structural efficacy of a new hyaluronic acid compound, NRD101, in comparison with diacerein and placebo in a 1 year randomised controlled study in symptomatic knee osteoarthritis.
Topics: Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Double-Blind Method; Female; Humans; Hyaluronic Acid; Injections, Intra-Articular; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Prospective Studies; Severity of Illness Index; Treatment Outcome | 2004 |
Evaluation of efficacy and safety of diacerein in knee osteoarthritis in Chinese patients.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Safety | 2006 |
The efficacy, safety and carry-over effect of diacerein in the treatment of painful knee osteoarthritis: a randomised, double-blind, NSAID-controlled study.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Piroxicam; Thailand | 2007 |
The efficacy and safety of diacerein in the treatment of painful osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled study with primary end points at two months after the end of a three-month treatment period.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Double-Blind Method; Endpoint Determination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Treatment Outcome | 2007 |
[Efficacy and tolerance of diacerhein in the treatment of gonarthrosis and coxarthrosis].
Topics: Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Treatment Outcome | 1998 |
Efficacy and safety of diacerein in osteoarthritis of the knee: a double-blind, placebo-controlled trial. The Diacerein Study Group.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Placebos; Therapeutic Equivalency | 2000 |
Harpagophytum procumbens in the treatment of knee and hip osteoarthritis. Four-month results of a prospective, multicenter, double-blind trial versus diacerhein.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Glycosides; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrans; Severity of Illness Index; Treatment Outcome | 2000 |
Efficacy and tolerance of Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis.
Topics: Adult; Aged; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Glycosides; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrans; Severity of Illness Index; Treatment Outcome | 2000 |
7 other study(ies) available for diacerein and Osteoarthritis, Knee
| Article | Year |
|---|---|
Clinical therapeutic effects of combined diacerein and glucosamine in the treatment of osteoarthritis: A protocol for systematic review and meta-analysis.
Topics: Anthraquinones; Glucosamine; Humans; Meta-Analysis as Topic; Osteoarthritis, Hip; Osteoarthritis, Knee; Systematic Reviews as Topic | 2021 |
[Efficacy of combined use of glycosaminoglycan peptide complex for intramuscular administration and oral diacerein in osteoarthritis: evaluation according to an observational multicenter clinical trial].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Glycosaminoglycans; Humans; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Peptides; Retrospective Studies; Treatment Outcome | 2021 |
Experimental osteoarthritis model by means of medial meniscectomy in rats and effects of diacerein administration and hyaluronic acid injection.
Topics: Administration, Oral; Animals; Anthraquinones; Anti-Inflammatory Agents; Arthritis, Experimental; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Hyaluronic Acid; Injections, Intra-Articular; Male; Menisci, Tibial; Osteoarthritis, Knee; Random Allocation; Rats, Wistar; Severity of Illness Index; Viscosupplements | 2015 |
Diacerein. A controversial EU re-evaluation upholds marketing authorisation, unfortunately.
Topics: Anthraquinones; Anti-Inflammatory Agents; Drug Approval; Europe; Humans; Osteoarthritis, Hip; Osteoarthritis, Knee; Patient Safety; Risk Assessment; Risk Factors; Treatment Outcome | 2015 |
[The Analysis of Efficacy of The Application of Interleukin-1 Inhibitor in the Complex Therapy of Secondary Osteoarthritis Taking Into Account the Dynamics of Clinical and Functional Indicators].
Topics: Adult; Anthraquinones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Combined Modality Therapy; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Interleukin-1; Laser Therapy; Male; Methotrexate; Middle Aged; Osteoarthritis, Knee; Patient Acuity; Quality of Life; Recovery of Function; Treatment Outcome | 2016 |
Diacerhein versus glucosamine in a rat model of osteoarthritis.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Glucosamine; Male; Menisci, Tibial; Osteoarthritis, Knee; Postoperative Care; Rats; Rats, Wistar; Severity of Illness Index; Stifle | 2006 |
Diacerein has a weak effect on the catabolic pathway of human osteoarthritis synovial fibroblast--comparison to its effects on osteoarthritic chondrocytes.
Topics: Anthraquinones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cells, Cultured; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Fibroblasts; Humans; Interleukin-1beta; Knee Joint; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; NF-kappa B; Nitrites; Osteoarthritis, Knee; Statistics, Nonparametric; Stimulation, Chemical; Synovial Membrane | 2008 |