diacerein has been researched along with Disease Models, Animal in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (25.00) | 18.2507 |
| 2000's | 8 (25.00) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 9 (28.13) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Abdelraheem, WM; El-Hussieny, M; Refaie, MMM | 1 |
| Abdel-Aziz, AM; Abdelzaher, WY; Alorabi, M; Bahaa, HA; Batiha, GE; Hegazy, A; Ibrahim, YF; Morsy, MA; Thabet, K; Toni, ND; Venugopala, KN; Welson, NN | 1 |
| Abdel-Nasser, ZM; Abdeldaiem, MSI; Abdelhady, R; Alhajlah, S; AlOmeir, O; Alrouji, M; El Adle Khalaf, N; El-Bahouty, WB; El-Gharbawy, DM; Elrabat, A; Ewees, MGE; Ghaffar, DMA; Haleem, AA; Kaddah, MMY; Mohammed, OA; Saber, S; Shata, A; Zakaria, S; Zohny, MH | 1 |
| Mir, MA; Olaniyi, KS; Shrivastava, VK; Ul Haq Shah, MZ | 1 |
| Abu Zeid, K; El-Nabarawi, MA; Fouad, SA; Malaak, FA | 1 |
| Cavenaghi Pereira da Silva, M; Correa Maldonado, D; Faber, J; Kerkis, I; Martinez Saez, D; Nicoliche, T; Tetsuo Sasaki, R | 1 |
| Abdel-Aziem, SH; Abdel-Aziz, MA; Abdel-Wahhab, MA; Ahmed, HMS; El-Nekeety, AA; Sharaf, HA | 1 |
| Eisa, NH; El-Din El-Agawy, MS; El-Shafey, M; El-Sherbiny, M; Elsherbiny, NM; Mohamed, AS | 1 |
| Arjinajarn, P; Chatsudthipong, V; Chattipakorn, N; Chueakula, N; Jaikumkao, K; Lungkaphin, A; Pongchaidecha, A | 1 |
| Bolliger Neto, R; Hernandez, AJ; Oliveira, CR; Rezende, MU | 1 |
| Ahmad, A; Allarà, M; Cuzzocrea, S; Di Marzo, V; Esposito, E; Marcolongo, G; Petrosino, S; Verde, R | 1 |
| de Carvalho, DD; de Oliveira, PP; de Souza Vilarinho, KA; do Carmo, HR; Lima, F; Petrucci, O; Reichert, K; Saad, MJ; Sposito, AC; Torina, AG | 1 |
| Caeiro, JR; González-Cantalapiedra, A; Guede, D; López-Peña, M; Muñoz, F; Permuy, M | 1 |
| Jatwa, R; Kar, A | 1 |
| Alves, SH; Andrighetto, R; Avila, DS; Ferreira, AP; Ferreira, J; Mello, CF; Pasin, JS; Ratzlaff, V; Rubin, MA; Santos, AR; Saraiva, AL; Tomazetti, J | 1 |
| Dhaneshwar, S; Patil, D | 1 |
| Colville-Nash, PR | 1 |
| Solignac, M | 1 |
| Dieppe, P | 1 |
| Calixto, JB; Campos, MM; Medeiros, R; Quintão, NLM; Santos, ARS | 1 |
| Ibanez, JF; Kitadai, FT; Kitadai, HK; Lucas, R; Milani, C; Straus, AH; Takahashi, HK | 1 |
| Gurgel, HM; Hernandez, AJ; Kuroba, RK; Lopes, AS; Phillipi, RZ; Rezende, MU; Vilaça Junior, PR | 1 |
| Berdah, L; Mazières, B; Thiéchart, M; Viguier, G | 1 |
| Blanckaert, A; Mazières, B; Thiéchart, M; Viguier, G | 1 |
| Alam, CA; Greenslade, KJ; Moore, AR; Willoughby, DA | 1 |
| Albrecht, M; Brandt, KD; Kang, SY; Myers, S; O'Connor, B; Smith, G | 2 |
| Burkhardt, D; Ghosh, P; Hwa, SY; Little, C; Xu, A | 1 |
| Albrecht, ME; Brandt, KD; Mickler, EA; Myers, SL; Smith, GN | 1 |
| Carney, SL | 1 |
| Ohmori, K; Tamura, T; Yokoyama, T | 1 |
1 review(s) available for diacerein and Disease Models, Animal
| Article | Year |
|---|---|
[Mechanisms of action of diacerein, the first inhibitor of interleukin-1 in osteoarthritis].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Chondrocytes; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Humans; Hyaluronic Acid; Interleukin-1; Osteoarthritis; Proteoglycans; Randomized Controlled Trials as Topic; Transforming Growth Factors; Treatment Outcome | 2004 |
1 trial(s) available for diacerein and Disease Models, Animal
| Article | Year |
|---|---|
[Diacetylrhein on a postcontusion model of experimental osteoarthritis in the rabbit].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Disease Models, Animal; Female; Knee Injuries; Osteoarthritis; Rabbits | 1993 |
30 other study(ies) available for diacerein and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Diacerein ameliorates induced polycystic ovary in female rats via modulation of inflammasome/caspase1/IL1β and Bax/Bcl2 pathways.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; bcl-2-Associated X Protein; Disease Models, Animal; Female; Inflammasomes; Interleukin-1beta; Letrozole; Polycystic Ovary Syndrome; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Salivary Proteins and Peptides | 2022 |
Diacerein ameliorates letrozole-induced polycystic ovarian syndrome in rats.
Topics: Animals; Anthraquinones; Disease Models, Animal; Female; Humans; Letrozole; Polycystic Ovary Syndrome; Rats; Rats, Wistar | 2022 |
Diacetylrhein, an anthraquinone antiarthritic agent, suppresses dextran sodium sulfate-induced inflammation in rats: A possible mechanism for a protective effect against ulcerative colitis.
Topics: Animals; Anthraquinones; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Inflammation; Rats; Sulfates | 2022 |
Role of diacerein on steroidogenesis and folliculogenesis related genes in ovary of letrozole-induced PCOS mice.
Topics: Animals; Disease Models, Animal; Estrogens; Female; Humans; Letrozole; Mice; Polycystic Ovary Syndrome | 2023 |
Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation.
Topics: Administration, Oral; Animals; Anthraquinones; Anti-Inflammatory Agents; Biological Availability; Capsules; Disease Models, Animal; Edema; Excipients; Male; Rats; Solubility; Tablets | 2020 |
Intra-articular human deciduous dental pulp stem cell administration vs. pharmacological therapy in experimental osteoarthritis rat model.
Topics: Animals; Anthraquinones; Chondroitin; Dental Pulp; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosamine; Humans; Injections, Intra-Articular; Male; Mesenchymal Stem Cells; Osteoarthritis; Rats; Rats, Wistar | 2021 |
Biosynthesis of gold nanoparticles for the treatment of osteoarthritis alone or in combination with Diacerein
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Chenopodium; Disease Models, Animal; Drug Therapy, Combination; Female; Gold; Iodoacetic Acid; Metal Nanoparticles; Osteoarthritis; Plant Extracts; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2021 |
Diacerein ameliorates testosterone-induced benign prostatic hyperplasia in rats: Effect on oxidative stress, inflammation and apoptosis.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cell Proliferation; Disease Models, Animal; Humans; Male; Oxidative Stress; Prostate; Prostatic Hyperplasia; Prostatitis; Rats; Testosterone | 2021 |
Diacerein alleviates kidney injury through attenuating inflammation and oxidative stress in obese insulin-resistant rats.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Antioxidants; Creatinine; Diet, High-Fat; Disease Models, Animal; Humans; Inflammation; Insulin Resistance; Kidney; Obesity; Organic Anion Transporters, Sodium-Independent; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase | 2018 |
Experimental osteoarthritis model by means of medial meniscectomy in rats and effects of diacerein administration and hyaluronic acid injection.
Topics: Administration, Oral; Animals; Anthraquinones; Anti-Inflammatory Agents; Arthritis, Experimental; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Hyaluronic Acid; Injections, Intra-Articular; Male; Menisci, Tibial; Osteoarthritis, Knee; Random Allocation; Rats, Wistar; Severity of Illness Index; Viscosupplements | 2015 |
Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain.
Topics: Amides; Amidohydrolases; Analgesics; Animals; Anthraquinones; Anti-Inflammatory Agents; Carrageenan; Disease Models, Animal; Ethanolamines; HEK293 Cells; Humans; Male; Pain; Palmitic Acids; Rats, Sprague-Dawley; Skin | 2015 |
Diacerein improves left ventricular remodeling and cardiac function by reducing the inflammatory response after myocardial infarction.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Caspase 3; Disease Models, Animal; Gene Expression Regulation; Myocardial Infarction; Rats; Rats, Wistar; Transcription Factor RelA; Ventricular Function, Left; Ventricular Remodeling | 2015 |
Comparison of various SYSADOA for the osteoarthritis treatment: an experimental study in rabbits.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Arthrography; Bone Density Conservation Agents; Cartilage, Articular; Chondroitin Sulfates; Disease Models, Animal; Drug Therapy, Combination; Female; Femur; Glucosamine; Hyaluronic Acid; Joints; Osteoarthritis; Rabbits; Risedronic Acid; Synovial Membrane; Tomography, X-Ray Computed | 2015 |
Anti-inflammatory and anti-peroxidative roles of diacerein are possibly mediated through an alteration in thyroid functions in animal model of inflammation.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Cholesterol; Disease Models, Animal; Female; Glutathione; Inflammation; Insulin; Lipid Peroxidation; Rats; Rats, Wistar; Thyroid Hormones; Triglycerides | 2009 |
Diacerein decreases TNF-alpha and IL-1beta levels in peritoneal fluid and prevents Baker's yeast-induced fever in young rats.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Ascitic Fluid; Body Temperature; Cell Movement; Dinoprostone; Disease Models, Animal; Fever; Interleukin-1beta; Leukocytes; Male; Rats; Rats, Wistar; Saccharomyces cerevisiae; Tumor Necrosis Factor-alpha | 2010 |
Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia.
Topics: Animals; Anthraquinones; Chondrocytes; Disease Models, Animal; Hyperalgesia; Iodoacetic Acid; Osteoarthritis; Prodrugs; Rats | 2013 |
[Comparison of the pharmacologic effect of diacerein and a selective COX-2 inhibitor in the mouse induced-granuloma model].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Isoenzymes; Membrane Proteins; Mice; Osteoarthritis; Prostaglandin-Endoperoxide Synthases | 2002 |
Disease modification in osteoarthritis: are drugs the answer?
Topics: Animals; Anthraquinones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Cartilage, Articular; Collagenases; Disease Models, Animal; Doxycycline; Enzyme Precursors; Humans; Osteoarthritis | 2005 |
The effects of diacerhein on mechanical allodynia in inflammatory and neuropathic models of nociception in mice.
Topics: Amines; Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Mice; Pain; Sciatic Neuropathy | 2005 |
Effect of oral diacerein (DAR) in an experimental hip chondrolysis model.
Topics: Acetabulum; Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Bone Wires; Cartilage Diseases; Cartilage, Articular; Complement C3; Complement C4; Disease Models, Animal; Dogs; Epiphyses, Slipped; Femur Head; Hip Joint; Hip Prosthesis; Immunoglobulins; Postoperative Complications; Prosthesis Failure; Proteoglycans; Synovial Membrane | 2006 |
Diacerhein versus glucosamine in a rat model of osteoarthritis.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Glucosamine; Male; Menisci, Tibial; Osteoarthritis, Knee; Postoperative Care; Rats; Rats, Wistar; Severity of Illness Index; Stifle | 2006 |
[Diacetylrhein administrated "curatively" in an experimental model of post-contusion osteoarthritis in rabbits].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage; Collagenases; Contusions; Disease Models, Animal; Osteoarthritis; Rabbits | 1996 |
[Effects of diacerhein on cytokine determinations in a model of cartilage degradation induced by granuloma in mice].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cytokines; Disease Models, Animal; Glycosaminoglycans; Granuloma; Hydroxyproline; Mice; Mice, Transgenic; Osteoarthritis | 1997 |
[Effects of diacerhein on canine model with accelerated osteoarthritis].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Disease Models, Animal; Dogs; Osteoarthritis; Proteoglycans | 1997 |
Effects of diacerhein in an accelerated canine model of osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament Injuries; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Cartilage Diseases; Cartilage, Articular; Collagenases; Disease Models, Animal; Dogs; Exudates and Transudates; Knee Joint; Male; Metalloendopeptidases; Osteoarthritis; Proteoglycans; Synovial Fluid; Synovial Membrane; Ulcer | 1997 |
[Evaluation of the effects of diacerhein in the sheep model of arthritis].
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Bone Density; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Male; Metalloendopeptidases; Sheep | 1998 |
Diacerhein treatment reduces the severity of osteoarthritis in the canine cruciate-deficiency model of osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Cartilage, Articular; Collagenases; Disease Models, Animal; Dogs; Femur; Joint Instability; Knee Joint; Organ Culture Techniques; Osteoarthritis; Proteoglycans; Synovial Fluid; Synovial Membrane | 1999 |
Effect of diacetyl rhein on the development of experimental osteoarthritis. A biochemical investigation.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cartilage, Articular; Cells, Cultured; Chondroitin Sulfates; Disease Models, Animal; Dogs; Epitopes; Glycosaminoglycans; Hydroxyproline; Osteoarthritis; Proteoglycans | 1996 |
Effects of diacerein on indomethacin-induced gastric ulceration.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dinoprostone; Disease Models, Animal; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Neutrophils; Rats; Reactive Oxygen Species; Stomach Ulcer | 2001 |