dextromethorphan and Cerebrovascular-Disorders

dextromethorphan has been researched along with Cerebrovascular-Disorders* in 1 studies

Trials

1 trial(s) available for dextromethorphan and Cerebrovascular-Disorders

ArticleYear
Safety and tolerance of oral dextromethorphan in patients at risk for brain ischemia.
    Stroke, 1991, Volume: 22, Issue:8

    Experimental ischemia models have shown the antitussive dextromethorphan to be an N-methyl-D-aspartate antagonist with neuroprotective properties. We treated 10 patients with a history of recent stroke or transient ischemic attack with oral dextromethorphan (60 mg q.i.d.) for 3 weeks in a placebo-controlled, double-blind, crossover tolerance study. We documented no clinical evidence of toxicity attributable to dextromethorphan in this preliminary study.

    Topics: Administration, Oral; Aged; Brain Ischemia; Cerebrovascular Disorders; Dextromethorphan; Double-Blind Method; Humans; Ischemic Attack, Transient; Middle Aged; Risk Factors

1991