dextromethorphan has been researched along with Cerebrovascular-Disorders* in 1 studies
1 trial(s) available for dextromethorphan and Cerebrovascular-Disorders
Article | Year |
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Safety and tolerance of oral dextromethorphan in patients at risk for brain ischemia.
Experimental ischemia models have shown the antitussive dextromethorphan to be an N-methyl-D-aspartate antagonist with neuroprotective properties. We treated 10 patients with a history of recent stroke or transient ischemic attack with oral dextromethorphan (60 mg q.i.d.) for 3 weeks in a placebo-controlled, double-blind, crossover tolerance study. We documented no clinical evidence of toxicity attributable to dextromethorphan in this preliminary study. Topics: Administration, Oral; Aged; Brain Ischemia; Cerebrovascular Disorders; Dextromethorphan; Double-Blind Method; Humans; Ischemic Attack, Transient; Middle Aged; Risk Factors | 1991 |