dextroamphetamine has been researched along with Tourette Syndrome in 22 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dextroamphetamine tended to produce more compulsive behaviors, which were also more likely to resemble clinical obsessive-compulsive disorder (OCD), than did methylphenidate." | 2.67 | Motor/vocal tics and compulsive behaviors on stimulant drugs: is there a common vulnerability? ( Amass, J; Borcherding, BG; Elia, J; Keysor, CS; Rapoport, JL, 1990) |
| "Early signs of Tourette's syndrome may be difficult to distinguish from hyperactive and attention disordered symptoms, leading the clinician to consider, treatment with stimulants." | 1.26 | Stimulant medications precipitate Tourette's syndrome. ( Cohen, DJ; Detlor, J; Kremenitzer, MW; Lowe, TL; Shaywitz, BA, 1982) |
| "Early signs of Tourette's syndrome may be difficult to distinguish from hyperactive and attention disordered symptoms, leading the clinician to consider treatment with stimulants." | 1.26 | Stimulant medications precipitate Tourette's syndrome. ( Cohen, DJ; Detlor, J; Kremenitzer, MW; Lowe, TL; Shaywitz, BA, 1982) |
| "Gilles de la Tourette's syndrome was independently ascertained in two male cousins once removed." | 1.26 | Gilles de la Tourette's syndrome. Familial occurrence and precipitation by methylphenidate therapy. ( Cohen, NL; Friedhoff, AJ; Pollack, MA, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (68.18) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Denys, D | 1 |
| de Vries, F | 1 |
| Cath, D | 1 |
| Figee, M | 1 |
| Vulink, N | 1 |
| Veltman, DJ | 1 |
| van der Doef, TF | 1 |
| Boellaard, R | 1 |
| Westenberg, H | 1 |
| van Balkom, A | 1 |
| Lammertsma, AA | 1 |
| van Berckel, BN | 1 |
| Benjamin, E | 1 |
| Salek, S | 1 |
| Lowe, TL | 2 |
| Cohen, DJ | 3 |
| Detlor, J | 2 |
| Kremenitzer, MW | 2 |
| Shaywitz, BA | 3 |
| Caine, ED | 2 |
| Ludlow, CL | 2 |
| Polinsky, RJ | 2 |
| Ebert, MH | 2 |
| Diamond, BI | 1 |
| Reyes, MG | 1 |
| Borison, R | 1 |
| Rapoport, JL | 3 |
| Nee, L | 1 |
| Mitchell, S | 1 |
| Polinsky, R | 1 |
| Ebert, M | 1 |
| Nee, LE | 1 |
| Hansen, N | 1 |
| Walkup, JT | 1 |
| Scahill, LD | 1 |
| Riddle, MA | 1 |
| Castellanos, FX | 2 |
| Giedd, JN | 1 |
| Elia, J | 2 |
| Marsh, WL | 1 |
| Ritchie, GF | 1 |
| Hamburger, SD | 1 |
| Pollack, MA | 1 |
| Cohen, NL | 1 |
| Friedhoff, AJ | 1 |
| Caparulo, B | 1 |
| Young, JG | 1 |
| Bowers, MB | 1 |
| Feinberg, M | 1 |
| Carroll, BJ | 1 |
| Borcherding, BG | 1 |
| Keysor, CS | 1 |
| Amass, J | 1 |
| Dulcan, MK | 1 |
| Dillon, DC | 1 |
| Salzman, IJ | 1 |
| Schulsinger, DA | 1 |
| Erenberg, G | 1 |
| Cruse, RP | 1 |
| Rothner, AD | 1 |
| Golden, GS | 1 |
| Meyerhoff, JL | 1 |
| Snyder, SH | 1 |
| Gadoth, N | 1 |
2 reviews available for dextroamphetamine and Tourette Syndrome
| Article | Year |
|---|---|
Disruptive behavior, hyperactivity, and learning disabilities in children with Tourette's syndrome.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; | 1995 |
Stimulants and tic disorders: from dogma to data.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Clinical Trials as | 1999 |
3 trials available for dextroamphetamine and Tourette Syndrome
| Article | Year |
|---|---|
Controlled stimulant treatment of ADHD and comorbid Tourette's syndrome: effects of stimulant and dose.
Topics: Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulan | 1997 |
Effects of dopamine agonists and antagonists in Tourette's disease.
Topics: Adolescent; Adult; Amphetamine; Apomorphine; Child; Clinical Trials as Topic; Dextroamphetamine; Dop | 1979 |
Motor/vocal tics and compulsive behaviors on stimulant drugs: is there a common vulnerability?
Topics: Attention Deficit Disorder with Hyperactivity; Child; Compulsive Behavior; Dextroamphetamine; Double | 1990 |
17 other studies available for dextroamphetamine and Tourette Syndrome
| Article | Year |
|---|---|
Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder.
Topics: Adult; Carbon Radioisotopes; Case-Control Studies; Corpus Striatum; Dextroamphetamine; Dopamine; Dop | 2013 |
Stimulant-atypical antipsychotic interaction and acute dystonia.
Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar | 2005 |
Stimulant medications precipitate Tourette's syndrome.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe | 1982 |
Provocative drug testing in Tourette's syndrome: d- and l-amphetamine and haloperidol.
Topics: Adolescent; Adult; Amphetamine; Child; Dextroamphetamine; Female; Haloperidol; Humans; Male; Tic Dis | 1984 |
Stimulant medications precipitate Tourette's syndrome.
Topics: Acute Disease; Amphetamines; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; | 1982 |
A new animal model for Tourette syndrome.
Topics: Animals; Apomorphine; Dextroamphetamine; Disease Models, Animal; Haloperidol; Humans; Male; Nitriles | 1982 |
Hyperkinetic syndrome and Tourette syndrome.
Topics: Adolescent; Child; Dextroamphetamine; Humans; Hyperkinesis; Male; Methylphenidate; Pemoline; Tourett | 1982 |
Heterogeneity and variability in Tourette syndrome.
Topics: Adult; Aged; Amphetamine; Child; Dextroamphetamine; Female; Haloperidol; Humans; Male; Phosphatidylc | 1982 |
[Improvement from multiple tics after dexamphetamine].
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Dextroamphetamine; Humans; Male; Tourette | 1995 |
Gilles de la Tourette's syndrome. Familial occurrence and precipitation by methylphenidate therapy.
Topics: Adult; Child; Dextroamphetamine; Haloperidol; Humans; Hyperkinesis; Male; Methylphenidate; Pedigree; | 1977 |
Chronic, multiple tics of Gilles de la Tourette's disease. CSF acid monoamine metabolites after probenecid administration.
Topics: Adolescent; Brain; Child; Dextroamphetamine; Dopamine; Female; Homovanillic Acid; Humans; Hydroxyind | 1978 |
Attention deficit disorder: evaluation and treatment.
Topics: Age Factors; Anorexia; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Body Height; | 1985 |
The use of imipramine in Tourette's syndrome and attention deficit disorder: case report.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe | 1985 |
Gilles de la Tourette's syndrome: effects of stimulant drugs.
Topics: Central Nervous System Stimulants; Child; Dextroamphetamine; Humans; Methylphenidate; Pemoline; Tic | 1985 |
The relationship between stimulant medication and tics.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe | 1988 |
Gilles de la Tourette's disease and minimal brain dysfunction: amphetamine isomers reveal catecholamine correlates in an affected patient.
Topics: Amphetamine; Attention Deficit Disorder with Hyperactivity; Brain; Child; Dextroamphetamine; Dopamin | 1973 |
[Gilles de la Tourette's syndrome].
Topics: Brain Chemistry; Catecholamines; Corpus Striatum; Dextroamphetamine; Haloperidol; Humans; Norepineph | 1974 |