Page last updated: 2024-11-07

dextroamphetamine and Serotonin Syndrome

dextroamphetamine has been researched along with Serotonin Syndrome in 2 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"A 6-year-old girl displayed symptoms of serotonin syndrome after accidental ingestion of Vyvanse (lisdexamfetamine dimesylate)."3.78Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl. ( Akingbola, OA; Singh, D, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akingbola, OA1
Singh, D1
Prior, FH1
Isbister, GK1
Dawson, AH1
Whyte, IM1

Other Studies

2 other studies available for dextroamphetamine and Serotonin Syndrome

ArticleYear
Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2012, Volume: 21, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Central Nervous System Stimulants; Child;

2012
Serotonin toxicity with therapeutic doses of dexamphetamine and venlafaxine.
    The Medical journal of Australia, 2002, Mar-04, Volume: 176, Issue:5

    Topics: Adult; Central Nervous System Stimulants; Cyclohexanols; Dextroamphetamine; Drug Interactions; Human

2002