Page last updated: 2024-11-07

dextroamphetamine and Psychoses, Drug

dextroamphetamine has been researched along with Psychoses, Drug in 40 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Research Excerpts

ExcerptRelevanceReference
"One of the most devastating consequences of methamphetamine abuse is increased risk of psychosis."3.83BDNF-Deficient Mice Show Reduced Psychosis-Related Behaviors Following Chronic Methamphetamine. ( Halberstadt, AL; Manning, EE; van den Buuse, M, 2016)
" While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs."2.49Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. ( Banaschewski, T; Buitelaar, J; Coghill, D; Cortese, S; Danckaerts, M; Dittmann, RW; Graham, J; Holtmann, M; Sergeant, J; Taylor, E, 2013)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199025 (62.50)18.7374
1990's5 (12.50)18.2507
2000's4 (10.00)29.6817
2010's5 (12.50)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Kooij, JJS1
Gomes, CAB1
Mahgoub, Y1
Manning, EE1
Halberstadt, AL1
van den Buuse, M1
Steinkellner, T1
Freissmuth, M1
Sitte, HH1
Montgomery, T1
Hirthler, MA1
Cortese, S1
Holtmann, M1
Banaschewski, T1
Buitelaar, J1
Coghill, D1
Danckaerts, M1
Dittmann, RW1
Graham, J1
Taylor, E1
Sergeant, J1
Martin, RS1
Secchi, RL1
Sung, E1
Lemaire, M1
Bonhaus, DW1
Hedley, LR1
Lowe, DA1
Spear, J1
Alderton, D1
KEITER, WE1
ARNOLD, JH1
BACHRICH, PR1
PROUT, CT1
FORREST, AD1
Calello, DP1
Osterhoudt, KC1
Andersen, MB1
Werge, T1
Fink-Jensen, A1
Ellison, GD1
Eison, MS1
Nielsen, EB1
Lyon, M1
Ellison, G2
Schiørring, E1
Segal, DS2
Kuczenski, R1
Robinson, TE1
Kolb, B1
Borowski, TB1
Kokkinidis, L1
Gold, MS1
Bowers, MB1
Angrist, B3
Gershon, S3
Oviasu, VO1
Allen, RP1
Safer, D1
Covi, L1
Sanfilipo, M1
Wolkin, A1
Lipton, J1
Zeigler, S1
Wilkins, J1
Ando, K1
Hironaka, N1
Yanagita, T1
van Kammen, DP1
Docherty, JP1
Marder, SR1
Rosenblatt, JE1
Bunney, WE1
Greenberg, BD1
Sathananthan, G1
Wilk, S1
Eisenberg, L1
Griffith, JD1
Cavanaugh, J1
Held, J1
Oates, JA1
Greenberg, LM1
Deem, MA1
McMahon, S1
Snyder, SH1
Aghajanian, GK1
Matthysse, S1
West, AP1
Ellinwood, EH1
Cohen, S1
Angrist, BM1
Shopsin, B1
Randrup, A1
Munkvad, I1
Todd, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Therapeutic Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Pediatric Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Cohorts (ADHD): a Randomized, Sham-controlled Study.[NCT06069323]80 participants (Anticipated)Interventional2023-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for dextroamphetamine and Psychoses, Drug

ArticleYear
The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and D-amphetamine.
    Biological chemistry, 2011, Volume: 392, Issue:1-2

    Topics: Amphetamines; Animals; Dextroamphetamine; Humans; Methamphetamine; Mitochondria; Molecular Structure

2011
Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents.
    Journal of child psychology and psychiatry, and allied disciplines, 2013, Volume: 54, Issue:3

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Blood Pressure

2013
Effects of psychostimulants on aggression.
    The Journal of nervous and mental disease, 1975, Volume: 160, Issue:2-1

    Topics: Adolescent; Aggression; Amphetamine; Animals; Child; Dextroamphetamine; Dogs; Dose-Response Relation

1975

Trials

4 trials available for dextroamphetamine and Psychoses, Drug

ArticleYear
Lithium attenuates the activation-euphoria but not the psychosis induced by d-amphetamine in schizophrenia.
    Psychopharmacology, 1985, Volume: 87, Issue:1

    Topics: Adolescent; Adult; Analysis of Variance; Dextroamphetamine; Euphoria; Female; Humans; Lithium; Male;

1985
Dextroamphetamine. Evaluation of psychomimetic properties in man.
    Archives of general psychiatry, 1972, Volume: 26, Issue:2

    Topics: Administration, Oral; Adult; Catecholamines; Central Nervous System; Clinical Trials as Topic; Depre

1972
Effects of dextroamphetamine, chlorpromazine, and hydroxyzine on behavior and performance in hyperactive children.
    The American journal of psychiatry, 1972, Volume: 129, Issue:5

    Topics: Child; Chlorpromazine; Clinical Trials as Topic; Depression; Dextroamphetamine; Dose-Response Relati

1972
Amphetamine abuse.
    Science (New York, N.Y.), 1971, Jan-29, Volume: 171, Issue:3969

    Topics: Acetylcholinesterase; Aggression; Amphetamine; Animals; Antisocial Personality Disorder; Behavior, A

1971

Other Studies

33 other studies available for dextroamphetamine and Psychoses, Drug

ArticleYear
[Risk of psychosis with treatment for ADHD].
    Nederlands tijdschrift voor geneeskunde, 2020, 08-27, Volume: 164

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

2020
Caffeine-Induced Psychosis in a Bodybuilder With Chronic Testosterone and Amphetamine/Dextroamphetamine Misuse.
    The primary care companion for CNS disorders, 2018, Jun-21, Volume: 20, Issue:3

    Topics: Amphetamine; Caffeine; Dextroamphetamine; Humans; Male; Middle Aged; Performance-Enhancing Substance

2018
BDNF-Deficient Mice Show Reduced Psychosis-Related Behaviors Following Chronic Methamphetamine.
    The international journal of neuropsychopharmacology, 2016, Volume: 19, Issue:4

    Topics: Amphetamine-Related Disorders; Animals; Brain-Derived Neurotrophic Factor; Central Nervous System St

2016
Change of shift. Of masses and men.
    Annals of emergency medicine, 2011, Volume: 57, Issue:6

    Topics: Amphetamine-Related Disorders; Dextroamphetamine; Emergency Service, Hospital; Female; Humans; Physi

2011
Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in the rat.
    Psychopharmacology, 2003, Volume: 165, Issue:2

    Topics: Animals; Antipsychotic Agents; Apomorphine; Arousal; Attention; Behavior, Animal; Cyclohexanols; Dex

2003
Psychosis associated with prescribed dexamphetamine use.
    The Australian and New Zealand journal of psychiatry, 2003, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants;

2003
Acute dexedrine intoxication in children.
    Archives of pediatrics, 1955, Volume: 72, Issue:4

    Topics: Amphetamine; Central Nervous System Agents; Child; Dextroamphetamine; Drug-Related Side Effects and

1955
NEW DRUGS OF ADDICTION?
    British medical journal, 1964, Mar-28, Volume: 1, Issue:5386

    Topics: Adolescent; Amobarbital; Barbiturates; Behavior, Addictive; Dextroamphetamine; Lysergic Acid Diethyl

1964
REACTIONS TO USE OF AMPHETAMINES AS OBSERVED IN A PSYCHIATRIC HOSPITAL.
    New York state journal of medicine, 1964, May-15, Volume: 64

    Topics: Alcoholism; Amobarbital; Amphetamine; Amphetamines; Barbiturates; Dextroamphetamine; Hospitals, Psyc

1964
DRUGS FOR DEPRESSION.
    British medical journal, 1964, Sep-19, Volume: 2, Issue:5411

    Topics: Amobarbital; Antidepressive Agents; Chlordiazepoxide; Depression; Depressive Disorder; Dextroampheta

1964
Acute psychosis associated with therapeutic use of dextroamphetamine.
    Pediatrics, 2004, Volume: 113, Issue:5

    Topics: Acute Disease; Central Nervous System Stimulants; Child; Dextroamphetamine; Humans; Male; Psychoses,

2004
The acetylcholinesterase inhibitor galantamine inhibits d-amphetamine-induced psychotic-like behavior in Cebus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 321, Issue:3

    Topics: Animals; Arousal; Behavior, Animal; Cebus; Cholinesterase Inhibitors; Dextroamphetamine; Dyskinesia,

2007
Continuous amphetamine intoxication: an animal model of the acute psychotic episode.
    Psychological medicine, 1983, Volume: 13, Issue:4

    Topics: Animals; Behavior, Animal; Caudate Nucleus; Dextroamphetamine; Disease Models, Animal; Dopamine; Hal

1983
Apparent hallucinations in monkeys during around-the-clock amphetamine for seven to fourteen days. Possible relevance to amphetamine psychosis.
    The Journal of nervous and mental disease, 1983, Volume: 171, Issue:4

    Topics: Animals; Behavior, Animal; Chlorocebus aethiops; Dextroamphetamine; Drug Implants; Grooming; Halluci

1983
Psychopathology induced by "speed drugs".
    Pharmacology, biochemistry, and behavior, 1981, Volume: 14 Suppl 1

    Topics: Animals; Behavior; Behavior, Animal; Chlorocebus aethiops; Dextroamphetamine; Female; Humans; Male;

1981
An escalating dose "binge" model of amphetamine psychosis: behavioral and neurochemical characteristics.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Apr-01, Volume: 17, Issue:7

    Topics: Animals; Brain; Caudate Nucleus; Dextroamphetamine; Disease Models, Animal; Dopamine; Dose-Response

1997
Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Nov-01, Volume: 17, Issue:21

    Topics: Amphetamine-Related Disorders; Animals; Brain Damage, Chronic; Central Nervous System Stimulants; De

1997
The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis.
    Behavioral neuroscience, 1998, Volume: 112, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acoustic Stimulation; Analysis of Varian

1998
Neurobiological vulnerability to low-dose amphetamine psychosis.
    The American journal of psychiatry, 1978, Volume: 135, Issue:12

    Topics: Adult; Dextroamphetamine; Disease Susceptibility; Dopamine; Dose-Response Relationship, Drug; Female

1978
Clinical response to several dopamine agonists in schizophrenic and nonschizophrenic subjects.
    Advances in biochemical psychopharmacology, 1977, Volume: 16

    Topics: Amphetamine; Dextroamphetamine; Dopamine; Humans; Levodopa; Male; Paranoid Disorders; Piribedil; Psy

1977
Abuse of stimulant drugs in Nigeria.
    The British journal of addiction to alcohol and other drugs, 1976, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Anxiety; Caffeine; Dextroamphetamine; Drug Synergism; Female; Humans; Male; Niger

1976
Amphetamine response and duration of illness in schizophrenia.
    Schizophrenia research, 1991, Volume: 5, Issue:3

    Topics: Adult; Aged; Dextroamphetamine; Female; Humans; Longitudinal Studies; Male; Middle Aged; Neurocognit

1991
A silicone pellet for continuous cocaine: comparison with continuous amphetamine.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:4

    Topics: Animals; Behavior, Animal; Cocaine; Dextroamphetamine; Disease Models, Animal; Drug Implants; Male;

1991
Psychotic manifestations in amphetamine abuse--experimental study on the mechanism of psychotic recurrence.
    Psychopharmacology bulletin, 1986, Volume: 22, Issue:3

    Topics: Animals; Conditioning, Operant; Dextroamphetamine; Disease Models, Animal; Male; Methamphetamine; Mi

1986
Acute and chronic behavioral interactions between phencyclidine (PCP) and amphetamine: evidence for a dopaminergic role in some PCP-induced behaviors.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:1

    Topics: Animals; Behavior, Animal; Dextroamphetamine; Drug Interactions; Humans; Male; Motor Activity; Phenc

1985
Amphetamine psychosis: behavioral and biochemical aspects.
    Journal of psychiatric research, 1974, Volume: 11

    Topics: Adolescent; Adult; Affect; Alcoholism; Amphetamine; Brain; Cognition Disorders; Delusions; Depressio

1974
Symposium: behavior modification by drugs. 3. The clinical use of stimulant drugs in children.
    Pediatrics, 1972, Volume: 49, Issue:5

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Feeding and Eat

1972
Amphetamine-type drugs for hyperactive children.
    The Medical letter on drugs and therapeutics, 1972, Mar-31, Volume: 14, Issue:7

    Topics: Appetite; Attention Deficit Disorder with Hyperactivity; Body Weight; Brain; Child; Dextroamphetamin

1972
Prospects for research on schizophrenia. V. Pharmacological observations, Drug-induced psychoses.
    Neurosciences Research Program bulletin, 1972, Volume: 10, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Chlorpromazine; Dextroamphetamine; Dopamine; Humans; Limbic System;

1972
Interaction of low-dose amphetamine use with schizophrenia in outpatients: three case reports.
    The American journal of psychiatry, 1974, Volume: 131, Issue:3

    Topics: Acute Disease; Adult; Ambulatory Care; Amphetamine; Dextroamphetamine; Dose-Response Relationship, D

1974
Comparative psychotomimetic effects of stereoisomers of amphetamine.
    Nature, 1971, Nov-19, Volume: 234, Issue:5325

    Topics: Amphetamine; Behavior; Blood Pressure; Body Temperature; Dextroamphetamine; Humans; Interview, Psych

1971
Stereotyped activities produced by amphetamine in several animal species and man.
    Psychopharmacologia, 1967, Volume: 11, Issue:4

    Topics: Animals; Behavior, Animal; Cats; Chickens; Columbidae; Dextroamphetamine; Female; Guinea Pigs; Haplo

1967
Lilliputian hallucinatiion complicatign dexamphetamine-amylobarbitone addiction.
    The British journal of addiction to alcohol and other drugs, 1968, Volume: 63, Issue:3

    Topics: Adolescent; Adult; Barbiturates; Dextroamphetamine; Humans; Introversion, Psychological; Male; Psych

1968