Page last updated: 2024-11-07

dextroamphetamine and Neoplasms

dextroamphetamine has been researched along with Neoplasms in 8 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Fatigue is very common in patients with cancer."2.74A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer. ( Auret, KA; Bremner, AP; Bulsara, M; Schug, SA, 2009)
"Fatigue is a highly prevalent and distressing symptom associated with significant psychological and functional morbidity and decreased quality of life among patients with cancer."2.46Psychostimulants for cancer-related fatigue. ( Alici, Y; Breitbart, W, 2010)
"Methylphenidate has been studied most and seems to be effective and well tolerated despite common side effects."2.44Update on psychotropic medications for cancer-related fatigue. ( Alici-Evcimen, Y; Breitbart, W, 2007)
"Depressive symptoms associated with cancer range from normal sadness through acute stress response to major depression."1.27Diagnosis and treatment of depression in the cancer patient. ( Holland, JC; Massie, MJ, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19902 (25.00)18.7374
1990's1 (12.50)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mustian, KM1
Alfano, CM1
Heckler, C1
Kleckner, AS1
Kleckner, IR1
Leach, CR1
Mohr, D1
Palesh, OG1
Peppone, LJ1
Piper, BF1
Scarpato, J1
Smith, T1
Sprod, LK1
Miller, SM1
Auret, KA1
Schug, SA1
Bremner, AP1
Bulsara, M1
Breitbart, W2
Alici, Y1
GRAHN, HV1
Alici-Evcimen, Y1
Massie, MJ1
Holland, JC1
Yee, JD1
Berde, CB1
Homsi, J1
Walsh, D1
Nelson, KA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Feasibility Study of a Hypnosis Intervention and a Cognitive Behavioral Therapy Intervention to Reduce Fatigue in Patients Undergoing Chemotherapy for Metastatic Colorectal Cancer[NCT04999306]60 participants (Anticipated)Interventional2023-05-17Recruiting
Clinical Study on Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Adjuvant Chemotherapy[NCT06137833]92 participants (Anticipated)Interventional2023-11-27Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for dextroamphetamine and Neoplasms

ArticleYear
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
    JAMA oncology, 2017, Jul-01, Volume: 3, Issue:7

    Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen

2017
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
    JAMA oncology, 2017, Jul-01, Volume: 3, Issue:7

    Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen

2017
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
    JAMA oncology, 2017, Jul-01, Volume: 3, Issue:7

    Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen

2017
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
    JAMA oncology, 2017, Jul-01, Volume: 3, Issue:7

    Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen

2017
Psychostimulants for cancer-related fatigue.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2010, Volume: 8, Issue:8

    Topics: Central Nervous System Stimulants; Dextroamphetamine; Fatigue; Humans; Methylphenidate; Neoplasms; W

2010
Update on psychotropic medications for cancer-related fatigue.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2007, Volume: 5, Issue:10

    Topics: Antidepressive Agents; Central Nervous System Stimulants; Dextroamphetamine; Fatigue; Humans; Methyl

2007
Psychostimulants in supportive care.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:5

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Child; Dextroamphetamine; Ephedrine; Humans; Men

2000

Trials

1 trial available for dextroamphetamine and Neoplasms

ArticleYear
A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer.
    Journal of pain and symptom management, 2009, Volume: 37, Issue:4

    Topics: Aged; Central Nervous System Stimulants; Dextroamphetamine; Double-Blind Method; Fatigue; Female; Hu

2009

Other Studies

3 other studies available for dextroamphetamine and Neoplasms

ArticleYear
Use of a d-amphetamine-amobarbital combination as an adjunct to the treatment of carcinoma.
    Journal of the American Geriatrics Society, 1954, Volume: 2, Issue:9

    Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Dext

1954
Diagnosis and treatment of depression in the cancer patient.
    The Journal of clinical psychiatry, 1984, Volume: 45, Issue:3 Pt 2

    Topics: Adjustment Disorders; Antidepressive Agents, Tricyclic; Asparaginase; Combined Modality Therapy; Dep

1984
Dextroamphetamine or methylphenidate as adjuvants to opioid analgesia for adolescents with cancer.
    Journal of pain and symptom management, 1994, Volume: 9, Issue:2

    Topics: Adjuvants, Pharmaceutic; Adolescent; Adult; Analgesics, Opioid; Dextroamphetamine; Female; Humans; M

1994