Page last updated: 2024-11-07

dextroamphetamine and Long Sleeper Syndrome

dextroamphetamine has been researched along with Long Sleeper Syndrome in 14 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Research Excerpts

ExcerptRelevanceReference
"Cataplexy was not affected by amphetamine treatment, but was abolished in two patients when clomipramine was given together with either amphetamine."6.64Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy. ( Fenton, GW; Parkes, JD, 1973)
"Cataplexy was not affected by amphetamine treatment, but was abolished in two patients when clomipramine was given together with either amphetamine."2.64Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy. ( Fenton, GW; Parkes, JD, 1973)
" While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs."2.49Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. ( Banaschewski, T; Buitelaar, J; Coghill, D; Cortese, S; Danckaerts, M; Dittmann, RW; Graham, J; Holtmann, M; Sergeant, J; Taylor, E, 2013)
" Chronic administration of lithium chloride or valproic acid, two clinically effective mood stabilizers, reverses the majority of these behavioral abnormalities."1.42Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression. ( Duan, S; Han, Y; Li, X; Lou, H; Lu, Y; Zhen, X; Zhou, R; Zhu, L, 2015)
"The daytime somnolence was confirmed objectively by polygraphic monitoring seven weeks to 4 1/2 months after the onset of clinical symptoms."1.27Mononucleosis and chronic daytime sleepiness. A long-term follow-up study. ( Guilleminault, C; Mondini, S, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, Y1
Raymer, BK1
Zhou, R1
Lu, Y1
Han, Y1
Li, X1
Lou, H1
Zhu, L1
Zhen, X1
Duan, S1
Cortese, S1
Holtmann, M1
Banaschewski, T1
Buitelaar, J1
Coghill, D1
Danckaerts, M1
Dittmann, RW1
Graham, J1
Taylor, E1
Sergeant, J1
Mena-Segovia, J1
Giordano, M1
SMITH, CM1
SOURS, JA1
WILLIAMSON, DM1
Conner, AE1
Oswald, I1
Guilleminault, C1
Mondini, S1
Parkes, JD1
Fenton, GW1
Livingston, S1
Pauli, LL1
Silver, LB1
Duffy, JP1
Davison, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Therapeutic Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Pediatric Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Cohorts (ADHD): a Randomized, Sham-controlled Study.[NCT06069323]80 participants (Anticipated)Interventional2023-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for dextroamphetamine and Long Sleeper Syndrome

ArticleYear
Sleep modulating agents.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agen

2019
Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents.
    Journal of child psychology and psychiatry, and allied disciplines, 2013, Volume: 54, Issue:3

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Blood Pressure

2013
NARCOLEPSY AND OTHER DISTURBANCES IN THE SLEEP-WAKING RHYTHM: A STUDY OF 115 CASES WITH REVIEW OF THE LITERATURE.
    The Journal of nervous and mental disease, 1963, Volume: 137

    Topics: Black People; Cataplexy; Craniocerebral Trauma; Depression; Dextroamphetamine; Encephalitis; Halluci

1963
The neurologic learning disability syndrome.
    American family physician, 1971, Volume: 4, Issue:1

    Topics: Anorexia Nervosa; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, C

1971

Trials

1 trial available for dextroamphetamine and Long Sleeper Syndrome

ArticleYear
Levo(-) amphetamine and dextro(+) amphetamine in the treatment of narcolepsy.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:6

    Topics: Adult; Amphetamine; Antidepressive Agents; Cataplexy; Dextroamphetamine; Electroencephalography; Eva

1973

Other Studies

9 other studies available for dextroamphetamine and Long Sleeper Syndrome

ArticleYear
Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2015, Dec-03, Volume: 63

    Topics: Adaptation, Ocular; Animals; Antidepressive Agents; Bipolar Disorder; Cathepsin D; Corticosterone; D

2015
Striatal dopaminergic stimulation produces c-Fos expression in the PPT and an increase in wakefulness.
    Brain research, 2003, Oct-03, Volume: 986, Issue:1-2

    Topics: Animals; Basal Ganglia Diseases; Cholinergic Fibers; Corpus Striatum; Dextroamphetamine; Dopamine; G

2003
Controlled observations on the single case.
    Canadian Medical Association journal, 1963, Feb-23, Volume: 88

    Topics: Central Nervous System Stimulants; Dextroamphetamine; Double-Blind Method; Epinephrine; Humans; Meth

1963
A CASE OF LONG-STANDING NARCOLEPSY IN A COALMINER.
    The Practitioner, 1964, Volume: 193

    Topics: Cataplexy; Coal Mining; Dextroamphetamine; Drug Therapy; Humans; Narcolepsy; Sleep Wake Disorders

1964
Sleep disturbance in hyperkinetic children.
    Virginia medical, 1977, Volume: 104, Issue:5

    Topics: Child; Child, Preschool; Dextroamphetamine; Female; Humans; Hyperkinesis; Male; Methylphenidate; Sle

1977
Psychological medicine. Sleep difficulties.
    British medical journal, 1975, Mar-08, Volume: 1, Issue:5957

    Topics: Aging; Beverages; Dextroamphetamine; Dreams; Female; Humans; Hypnotics and Sedatives; Male; Mental D

1975
Mononucleosis and chronic daytime sleepiness. A long-term follow-up study.
    Archives of internal medicine, 1986, Volume: 146, Issue:7

    Topics: Adolescent; Adult; Chronic Disease; Circadian Rhythm; Dextroamphetamine; Disorders of Excessive Somn

1986
Letter: Sleep epilepsy.
    British medical journal, 1974, Oct-12, Volume: 4, Issue:5936

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Delayed-Action Preparations; Dextroamphetam

1974
A female case of the Kleine-Levin Syndrome.
    The British journal of psychiatry : the journal of mental science, 1968, Volume: 114, Issue:506

    Topics: Adolescent; Adult; Age Factors; Child; Dextroamphetamine; Feeding and Eating Disorders; Female; Huma

1968