dextroamphetamine has been researched along with Inflammation in 2 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is the first report of the pharmacodynamic (PD) effects of the selective, potent and brain-penetrant P2X7 receptor (P2X7R) antagonist JNJ-54175446." | 2.94 | Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial. ( de Boer, P; de Kam, M; Drevets, W; Jacobs, G; Kanhai, K; Ravenstijn, P; Recourt, K; Siebenga, P; Timmers, M; van der Aart, J; van Gerven, J; van Nueten, L; Zuiker, R, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Recourt, K | 1 |
| van der Aart, J | 1 |
| Jacobs, G | 1 |
| de Kam, M | 1 |
| Drevets, W | 1 |
| van Nueten, L | 1 |
| Kanhai, K | 1 |
| Siebenga, P | 1 |
| Zuiker, R | 1 |
| Ravenstijn, P | 1 |
| Timmers, M | 1 |
| van Gerven, J | 1 |
| de Boer, P | 1 |
| Valvassori, SS | 1 |
| Dal-Pont, GC | 1 |
| Tonin, PT | 1 |
| Varela, RB | 1 |
| Ferreira, CL | 1 |
| Gava, FF | 1 |
| Andersen, ML | 1 |
| Soares, JC | 1 |
| Quevedo, J | 1 |
1 trial available for dextroamphetamine and Inflammation
| Article | Year |
|---|---|
Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial.
Topics: Adolescent; Adult; Central Nervous System Stimulants; Depressive Disorder, Major; Dextroamphetamine; | 2020 |
1 other study available for dextroamphetamine and Inflammation
| Article | Year |
|---|---|
Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimanic Agents; Behavior, | 2019 |