dextroamphetamine has been researched along with Idiopathic Hypersomnia in 2 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
Idiopathic Hypersomnia: A sleep disorder of central nervous system origin characterized by prolonged nocturnal sleep and periods of daytime drowsiness. Affected individuals experience difficulty with awakening in the morning and may have associated sleep drunkenness, automatic behaviors, and memory disturbances. This condition differs from narcolepsy in that daytime sleep periods are longer, there is no association with CATAPLEXY, and the multiple sleep latency onset test does not record sleep-onset rapid eye movement sleep. (From Chokroverty, Sleep Disorders Medicine, 1994, pp319-20; Psychiatry Clin Neurosci 1998 Apr:52(2):125-129)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methylphenidate was most commonly used as a first-line agent prior to December 1998, but subsequently, modafinil became the most common first drug." | 1.35 | Idiopathic hypersomnia: clinical features and response to treatment. ( Ali, M; Auger, RR; Morgenthaler, TI; Slocumb, NL, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, M | 1 |
| Auger, RR | 1 |
| Slocumb, NL | 1 |
| Morgenthaler, TI | 1 |
| Quinnell, TG | 1 |
| Smith, IE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Signal Based Monitoring System for CNS Hypersomnias : A 10-year Longitudinal Study[NCT05443373] | 600 participants (Anticipated) | Observational | 2020-06-04 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for dextroamphetamine and Idiopathic Hypersomnia
| Article | Year |
|---|---|
Idiopathic hypersomnia: clinical features and response to treatment.
Topics: Actigraphy; Adult; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Dextroamphetam | 2009 |
Narcolepsy, idiopathic hypersomnolence and related conditions.
Topics: Antidepressive Agents, Tricyclic; Benzhydryl Compounds; Catalepsy; Central Nervous System Stimulants | 2011 |