dextroamphetamine has been researched along with Heroin Abuse in 7 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After oral administration, tmax values (coefficient of variation %) were 6." | 2.87 | Pharmacokinetics of Sustained-Release Oral Dexamphetamine Sulfate in Cocaine and Heroin-Dependent Patients. ( Beijnen, JH; Blanken, P; Hendriks, VM; Herbrink, M; Huitema, ADR; Janmohamed, A; Nuijen, B; Nuijten, M; van den Brink, W, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Blanken, P | 3 |
| Nuijten, M | 3 |
| van den Brink, W | 3 |
| Hendriks, VM | 3 |
| Herbrink, M | 1 |
| Nuijen, B | 2 |
| Huitema, ADR | 1 |
| Beijnen, JH | 1 |
| Janmohamed, A | 1 |
| Chen, LY | 1 |
| Crum, RM | 1 |
| Strain, EC | 1 |
| Martins, SS | 1 |
| Mojtabai, R | 1 |
| van de Wetering, B | 1 |
| Leri, F | 1 |
| Nahas, E | 1 |
| Henderson, K | 1 |
| Limebeer, CL | 1 |
| Parker, LA | 1 |
| White, NM | 1 |
| Grabowski, J | 1 |
| Rhoades, H | 1 |
| Stotts, A | 1 |
| Cowan, K | 1 |
| Kopecky, C | 1 |
| Dougherty, A | 1 |
| Moeller, FG | 1 |
| Hassan, S | 1 |
| Schmitz, J | 1 |
| Mello, NK | 1 |
| Lukas, SE | 1 |
| Mendelson, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of 24 Weeks Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder With Comorbid Opioid Use Disorder - A Multicenter Randomized, Double-blind, Placebo-controlled Study[NCT05529927] | Phase 2 | 204 participants (Anticipated) | Interventional | 2024-03-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for dextroamphetamine and Heroin Abuse
| Article | Year |
|---|---|
Clinical effects beyond cocaine use of sustained-release dexamphetamine for the treatment of cocaine dependent patients with comorbid opioid dependence: secondary analysis of a double-blind, placebo-controlled randomized trial.
Topics: Adult; Central Nervous System Stimulants; Cocaine-Related Disorders; Delayed-Action Preparations; De | 2020 |
Pharmacokinetics of Sustained-Release Oral Dexamphetamine Sulfate in Cocaine and Heroin-Dependent Patients.
Topics: Administration, Oral; Adult; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine-Rela | 2018 |
Sustained-release dexamfetamine in the treatment of chronic cocaine-dependent patients on heroin-assisted treatment: a randomised, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Central Nervous System Stimulants; Chronic Disease; Cocaine-Related Disorders; | 2016 |
Agonist-like or antagonist-like treatment for cocaine dependence with methadone for heroin dependence: two double-blind randomized clinical trials.
Topics: Adolescent; Adult; Blood Pressure; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; | 2004 |
Buprenorphine effects on cigarette smoking.
Topics: Adult; Buprenorphine; Dextroamphetamine; Dose-Response Relationship, Drug; Endorphins; Ethanol; Hero | 1985 |
2 other studies available for dextroamphetamine and Heroin Abuse
| Article | Year |
|---|---|
Patterns of concurrent substance use among adolescent nonmedical ADHD stimulant users.
Topics: Adolescent; Amphetamines; Analgesics, Opioid; Central Nervous System Stimulants; Child; Cocaine-Rela | 2015 |
Effects of post-training heroin and d-amphetamine on consolidation of win-stay learning and fear conditioning.
Topics: Amphetamine-Related Disorders; Animals; Avoidance Learning; Behavior, Animal; Central Nervous System | 2013 |