dextroamphetamine has been researched along with Fatigue in 27 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This report documents findings from a small placebo-controlled trial of dextroamphetamine for depression and fatigue in men with the human immunodeficiency virus (HIV)." | 9.09 | Effects of dextroamphetamine on depression and fatigue in men with HIV: a double-blind, placebo-controlled trial. ( Rabkin, R; Wagner, GJ, 2000) |
| "Dextroamphetamine (Dexedrine) is an effective fatigue countermeasure for use in military subject pilots who are deprived of sleep." | 5.10 | Utility of dextroamphetamine for attenuating the impact of sleep deprivation in pilots. ( Caldwell, JA; Caldwell, JL; Darlington, KK, 2003) |
| "This report documents findings from a small placebo-controlled trial of dextroamphetamine for depression and fatigue in men with the human immunodeficiency virus (HIV)." | 5.09 | Effects of dextroamphetamine on depression and fatigue in men with HIV: a double-blind, placebo-controlled trial. ( Rabkin, R; Wagner, GJ, 2000) |
| "B-2 pilots in long-duration combat flight selectively employ dextroamphetamine, naps, and other fatigue countermeasures." | 3.72 | Dextroamphetamine use during B-2 combat missions. ( Bird, CT; Fischer, JR; Kenagy, DN; Webber, CM, 2004) |
| "Fatigue is a common and disabling symptom in people with a primary brain tumour (PBT)." | 2.82 | Interventions for the management of fatigue in adults with a primary brain tumour. ( Bulbeck, H; Cachia, D; Day, J; Rooney, AG; Tremont Lukats, IW; Wefel, J; Yust-Katz, S, 2022) |
| "Fatigue is very common in patients with cancer." | 2.74 | A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer. ( Auret, KA; Bremner, AP; Bulsara, M; Schug, SA, 2009) |
| "Fatigue is a highly prevalent and distressing symptom associated with significant psychological and functional morbidity and decreased quality of life among patients with cancer." | 2.46 | Psychostimulants for cancer-related fatigue. ( Alici, Y; Breitbart, W, 2010) |
| "Methylphenidate has been studied most and seems to be effective and well tolerated despite common side effects." | 2.44 | Update on psychotropic medications for cancer-related fatigue. ( Alici-Evcimen, Y; Breitbart, W, 2007) |
| " Twenty-four men entered the study, 18 of 19 (95%) patients who completed at least 6 weeks of treatment reported substantial improvement with regard to both mood and energy at a median dosage of 10 mg/day." | 1.30 | Dextroamphetamine as a treatment for depression and low energy in AIDS patients: a pilot study. ( Rabkin, JG; Rabkin, R; Wagner, GJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (33.33) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 9 (33.33) | 29.6817 |
| 2010's | 6 (22.22) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Day, J | 1 |
| Yust-Katz, S | 1 |
| Cachia, D | 1 |
| Wefel, J | 1 |
| Tremont Lukats, IW | 1 |
| Bulbeck, H | 1 |
| Rooney, AG | 1 |
| Check, JH | 2 |
| Jaffe, A | 1 |
| Cohen, R | 1 |
| Mustian, KM | 1 |
| Alfano, CM | 1 |
| Heckler, C | 1 |
| Kleckner, AS | 1 |
| Kleckner, IR | 1 |
| Leach, CR | 1 |
| Mohr, D | 1 |
| Palesh, OG | 1 |
| Peppone, LJ | 1 |
| Piper, BF | 1 |
| Scarpato, J | 1 |
| Smith, T | 1 |
| Sprod, LK | 1 |
| Miller, SM | 1 |
| Russo, MB | 1 |
| Arnett, MV | 1 |
| Thomas, ML | 1 |
| Caldwell, JA | 2 |
| Auret, KA | 1 |
| Schug, SA | 1 |
| Bremner, AP | 1 |
| Bulsara, M | 1 |
| Gore, RK | 1 |
| Webb, TS | 1 |
| Hermes, ED | 1 |
| Breitbart, W | 2 |
| Alici, Y | 1 |
| Estrada, A | 1 |
| Kelley, AM | 1 |
| Webb, CM | 1 |
| Athy, JR | 1 |
| Crowley, JS | 1 |
| JAFFE, I | 1 |
| KISSIN, B | 1 |
| ROSENBLATT, P | 1 |
| PICKARD, K | 1 |
| GALLOP, C | 1 |
| TETREAULT, L | 1 |
| Caldwell, JL | 1 |
| Darlington, KK | 1 |
| Kenagy, DN | 1 |
| Bird, CT | 1 |
| Webber, CM | 1 |
| Fischer, JR | 1 |
| Contreras, M | 1 |
| Ceric, F | 1 |
| Torrealba, F | 1 |
| Alici-Evcimen, Y | 1 |
| Emonson, DL | 1 |
| Vanderbeek, RD | 1 |
| Wagner, GJ | 2 |
| Rabkin, JG | 1 |
| Rabkin, R | 2 |
| Justice, AJ | 1 |
| De Wit, H | 1 |
| Mills, KC | 1 |
| Spruill, SE | 1 |
| Kanne, RW | 1 |
| Parkman, KM | 1 |
| Zhang, Y | 1 |
| Cole, JO | 1 |
| Pope, HG | 1 |
| LaBrie, R | 1 |
| Ionescu-Pioggia, M | 1 |
| Gerald, MC | 1 |
| Shah, LP | 1 |
| Sethy, VH | 1 |
| Inamdar, SC | 1 |
| Vaidya, AB | 1 |
| Sheth, UK | 1 |
| Hollister, LE | 1 |
| Gillespie, HK | 1 |
| Malitz, S | 1 |
| Kanzler, M | 1 |
| Kiplinger, GF | 1 |
| Latz, A | 1 |
| Kornetsky, C | 1 |
| Bain, G | 1 |
| Goldman, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Feasibility Study of a Hypnosis Intervention and a Cognitive Behavioral Therapy Intervention to Reduce Fatigue in Patients Undergoing Chemotherapy for Metastatic Colorectal Cancer[NCT04999306] | 60 participants (Anticipated) | Interventional | 2023-05-17 | Recruiting | |||
| Clinical Study on Wide Spectrum Micronutrients Supplementation in Patients With Cancer Related Fatigue During Adjuvant Chemotherapy[NCT06137833] | 92 participants (Anticipated) | Interventional | 2023-11-27 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for dextroamphetamine and Fatigue
| Article | Year |
|---|---|
Interventions for the management of fatigue in adults with a primary brain tumour.
Topics: Adult; Brain Neoplasms; Dextroamphetamine; Fatigue; Glioma; Humans; Modafinil | 2022 |
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen | 2017 |
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen | 2017 |
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen | 2017 |
Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue: A Meta-analysis.
Topics: Benzhydryl Compounds; Central Nervous System Stimulants; Cognitive Behavioral Therapy; Dexmethylphen | 2017 |
Psychostimulants for cancer-related fatigue.
Topics: Central Nervous System Stimulants; Dextroamphetamine; Fatigue; Humans; Methylphenidate; Neoplasms; W | 2010 |
Update on psychotropic medications for cancer-related fatigue.
Topics: Antidepressive Agents; Central Nervous System Stimulants; Dextroamphetamine; Fatigue; Humans; Methyl | 2007 |
10 trials available for dextroamphetamine and Fatigue
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer.
Topics: Aged; Central Nervous System Stimulants; Dextroamphetamine; Double-Blind Method; Fatigue; Female; Hu | 2009 |
Modafinil as a replacement for dextroamphetamine for sustaining alertness in military helicopter pilots.
Topics: Adult; Aerospace Medicine; Aircraft; Arousal; Benzhydryl Compounds; Central Nervous System Stimulant | 2012 |
Utility of dextroamphetamine for attenuating the impact of sleep deprivation in pilots.
Topics: Adult; Aerospace Medicine; Dextroamphetamine; Fatigue; Female; Humans; Male; Military Personnel; Pol | 2003 |
Acute effects of d-amphetamine during the early and late follicular phases of the menstrual cycle in women.
Topics: Adolescent; Adult; Analysis of Variance; Anxiety; Behavior; Central Nervous System Stimulants; Dextr | 2000 |
Effects of dextroamphetamine on depression and fatigue in men with HIV: a double-blind, placebo-controlled trial.
Topics: Adult; Central Nervous System Stimulants; Cognition; Comorbidity; Depressive Disorder; Dextroampheta | 2000 |
The influence of stimulants, sedatives, and fatigue on tunnel vision: risk factors for driving and piloting.
Topics: Alcohol Drinking; Alprazolam; Analysis of Variance; Automobile Driving; Aviation; Central Nervous Sy | 2001 |
Assessing the subjective effects of stimulants in casual users. A methodology and preliminary results.
Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Depression; Dextroamphetamine; Emotions | 1978 |
Clinical trials of norcamphane hydrochloride in fatigue states. II. A double blind comparison with d-amphetamine sulfate.
Topics: Adult; Camphor; Clinical Trials as Topic; Dextroamphetamine; Fatigue; Female; Humans; Male; Middle A | 1967 |
Marihuana, ethanol, and dextroamphetamine. Mood and mental function alterations.
Topics: Adult; Analysis of Variance; Cannabis; Clinical Trials as Topic; Dextroamphetamine; Emotions; Ethano | 1970 |
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as | 1971 |
13 other studies available for dextroamphetamine and Fatigue
| Article | Year |
|---|---|
Dextroamphetamine sulfate provided quick relief of severe post-partum depression that was recalcitrant to standard antidepressants and psychotherapy.
Topics: Adult; Antidepressive Agents; Central Nervous System Stimulants; Depression, Postpartum; Dextroamphe | 2017 |
Severe headaches from intracranial hypertension (pseudotumor cerebri) abrogated by treatment with dextroamphetamine sulfate.
Topics: Adult; Back Pain; Dextroamphetamine; Fatigue; Female; Humans; Papilledema; Pseudotumor Cerebri; Symp | 2014 |
Ethical use of cogniceuticals in the militaries of democratic nations.
Topics: Benzhydryl Compounds; Caffeine; Canada; Central Nervous System Stimulants; Cognition; Cross-Cultural | 2008 |
Fatigue and stimulant use in military fighter aircrew during combat operations.
Topics: Adult; Aerospace Medicine; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Circad | 2010 |
Studies in psychic fatigue. II. Physiological effects of D-amphetamine.
Topics: Amphetamine; Amphetamines; Dextroamphetamine; Fatigue; Humans | 1959 |
[COMPARATIVE EVALUATION OF THE SUBJECTIVE EFFECTS OF DEXTROAMPHETAMINE, METHYLPHENIDATE AND PLACEBO].
Topics: Appetite; Biomedical Research; Central Nervous System Stimulants; Dextroamphetamine; Double-Blind Me | 1964 |
Dextroamphetamine use during B-2 combat missions.
Topics: Adult; Aerospace Medicine; Aviation; Caffeine; Central Nervous System Stimulants; Chi-Square Distrib | 2004 |
Inactivation of the interoceptive insula disrupts drug craving and malaise induced by lithium.
Topics: Amphetamine-Related Disorders; Animals; Behavior, Addictive; Behavior, Animal; Cerebral Cortex; Cond | 2007 |
The use of amphetamines in U.S. Air Force tactical operations during Desert Shield and Storm.
Topics: Aerospace Medicine; Dextroamphetamine; Drug Administration Schedule; Fatigue; Humans; Iraq; Military | 1995 |
Dextroamphetamine as a treatment for depression and low energy in AIDS patients: a pilot study.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; CD4 Lymphocyte Count; Central Nervous S | 1997 |
Effects of (+)-amphetamine on the treadmill endurance performance of rats.
Topics: Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Fatigue; Male; Physical Exertion; Rats | 1978 |
The effects of drugs on the rate of development of fatigue in mice.
Topics: Amphetamine; Animals; Dextroamphetamine; Fatigue; Imipramine; Male; Methods; Mice; Morphine; Pentoba | 1967 |
Swimming performance of mice as affected by antidepressant drugs and baseline levels.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Deanol; Desipramine; Dextroamphetamine; Fatigue; I | 1966 |