dextroamphetamine has been researched along with Drug Withdrawal Symptoms in 84 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study examines the effects of chronic lithium administration on changes induced by amphetamine administration and withdrawal on open field locomotor activity of rats, and considered as an animal model of behaviors displayed in bipolar disorders." | 7.68 | Effects of lithium on an amphetamine animal model of bipolar disorder. ( Cappeliez, P; Moore, E, 1990) |
| "Aggression, which is normally seen during withdrawal from narcotics, could not be produced in morphine-dependent rats by the administration of naloxone at doses which causes other signs of withdrawal." | 7.65 | Paradoxical absence of aggression during naloxone-precipitated morphine withdrawal. ( Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H, 1975) |
| "Bupropion is used clinically as a treatment for smoking cessation, but the processes by which it reduces smoking are poorly understood." | 5.09 | Acute doses of d-amphetamine and bupropion increase cigarette smoking. ( Cousins, MS; de Wit, H; Stamat, HM, 2001) |
| "Our results demonstrated that, at the seventh or 14th day of D-amphetamine or nicotine withdrawal, respectively, mice exhibited increased anxiety and depression-like effects, memory impairment and hyperalgesia." | 3.80 | Influence of calcium channel antagonists on nonsomatic signs of nicotine and D-amphetamine withdrawal in mice. ( Biała, G; Budzyńska, B; Kruk-Słomka, M; Michalak, A; Polak, P, 2014) |
| " This study examines the effects of chronic lithium administration on changes induced by amphetamine administration and withdrawal on open field locomotor activity of rats, and considered as an animal model of behaviors displayed in bipolar disorders." | 3.68 | Effects of lithium on an amphetamine animal model of bipolar disorder. ( Cappeliez, P; Moore, E, 1990) |
| "Aggression, which is normally seen during withdrawal from narcotics, could not be produced in morphine-dependent rats by the administration of naloxone at doses which causes other signs of withdrawal." | 3.65 | Paradoxical absence of aggression during naloxone-precipitated morphine withdrawal. ( Drawbaugh, RB; Gianutsos, G; Hynes, MD; Lal, H, 1975) |
| "At follow-up, degree of methamphetamine dependence was significantly lower in the dexamphetamine group (P = 0." | 2.75 | Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence. ( Cahill, S; Harrison, S; Longo, M; Smout, M; White, JM; Wickes, W, 2010) |
| "Methylphenidate was intermediate in efficacy between d-amphetamine and l-amphetamine." | 2.64 | Comparative effects of d-amphetamine, l-amphetamine, and methylphenidate on mood in man. ( Davis, JM; Smith, RC, 1977) |
| "Amphetamine withdrawal has been less studied although it is a common problem with a prevalent rate of 87% among amphetamine users." | 2.41 | Treatment for amphetamine withdrawal. ( Jarusuraisin, N; Kittirattanapaiboon, P; Srisurapanont, M, 2001) |
| " CD-1 mice were subcutaneously dosed for 5 days with 1." | 1.42 | Amphetamine sensitization in mice is sufficient to produce both manic- and depressive-related behaviors as well as changes in the functional connectivity of corticolimbic structures. ( Baker, K; Ibrahim, BA; Kelly, MP; McCarthy, SA; Pathak, G, 2015) |
| "Amphetamine was given twice daily 5 days per week for 6 weeks at dosages escalating from 1 to 10 mg/kg per injection." | 1.29 | Withdrawal from chronic amphetamine elevates baseline intracranial self-stimulation thresholds. ( Munn, E; Wise, RA, 1995) |
| "Aminorex is a cyclic phenylisopropylamine that has been marketed as an anorectic." | 1.29 | Evaluation of the abuse liability of aminorex. ( Harris, LS; Massey, BW; Patrick, GA; Winger, G; Woolverton, WL, 1994) |
| "In order to determine whether alterations in sensitivity to rewarding stimuli accompany the biochemical and behavioral changes induced by chronic amphetamine treatment and withdrawal, we explored the effects of chronic administration and withdrawal of d-amphetamine on thresholds of intracranial reinforcement in the rat." | 1.26 | Amphetamine withdrawal: effects on threshold of intracranial reinforcement. ( Actor, C; Cassens, G; Kling, M; Schildkraut, JJ, 1981) |
| "The chronic administration of several psychoactive drugs has been suggested to produce behavioral withdrawal syndromes in the absence of physical withdrawal." | 1.26 | Behavioral withdrawal following several psychoactive drugs. ( Annau, Z; Simpson, DM, 1977) |
| " After acute and chronic administration of (+)-amphetamine (2." | 1.26 | The effects of chronic administration and withdrawal of (+)-amphetamine on seizure threshold and endogenous catecholamine concentrations and their rates of biosynthesis in mice. ( Gerald, MC; Riffee, WH, 1977) |
| "Reserpine pretreatment eliminated the differences between control and withdrawn animals." | 1.26 | Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat. ( Hitzemann, BA; Hitzemann, RJ; Loh, HH; Sampath-Khanna, S; Tseng, LF, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (44.05) | 18.7374 |
| 1990's | 16 (19.05) | 18.2507 |
| 2000's | 18 (21.43) | 29.6817 |
| 2010's | 12 (14.29) | 24.3611 |
| 2020's | 1 (1.19) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, RG | 1 |
| Oliveto, A | 1 |
| Thostenson, JD | 1 |
| Wilson, MP | 1 |
| McGaugh, J | 1 |
| Mancino, MJ | 1 |
| Murray, RC | 2 |
| Hebbard, JC | 1 |
| Logan, AS | 1 |
| Vanchipurakel, GA | 1 |
| Gilbert, YE | 2 |
| Horner, KA | 3 |
| Biała, G | 1 |
| Polak, P | 1 |
| Michalak, A | 1 |
| Kruk-Słomka, M | 1 |
| Budzyńska, B | 1 |
| Pathak, G | 1 |
| Ibrahim, BA | 1 |
| McCarthy, SA | 1 |
| Baker, K | 1 |
| Kelly, MP | 1 |
| Fuller, JJ | 1 |
| Shoptaw, SJ | 1 |
| Kao, U | 1 |
| Heinzerling, K | 1 |
| Ling, W | 1 |
| Gipson, CD | 1 |
| Bardo, MT | 1 |
| Longo, M | 1 |
| Wickes, W | 1 |
| Smout, M | 1 |
| Harrison, S | 1 |
| Cahill, S | 1 |
| White, JM | 1 |
| Häggkvist, J | 1 |
| Björkholm, C | 1 |
| Steensland, P | 1 |
| Lindholm, S | 1 |
| Franck, J | 2 |
| Schilström, B | 1 |
| Zhornitsky, S | 1 |
| Potvin, S | 1 |
| Stip, E | 1 |
| Rompré, PP | 1 |
| Scholl, JL | 1 |
| Vuong, SM | 1 |
| Forster, GL | 1 |
| Greenwald, MK | 1 |
| Lundahl, LH | 1 |
| Steinmiller, CL | 1 |
| Gruner, JA | 1 |
| Mathiasen, JR | 1 |
| Flood, DG | 1 |
| Gasior, M | 2 |
| Noble, ES | 1 |
| Brams, M | 1 |
| Weisler, R | 1 |
| Findling, RL | 1 |
| Hamdani, M | 1 |
| Ferreira-Cornwell, MC | 1 |
| Squires, L | 1 |
| Russig, H | 3 |
| Murphy, CA | 2 |
| Feldon, J | 4 |
| Cohen, C | 1 |
| Bergis, OE | 1 |
| Galli, F | 1 |
| Lochead, AW | 1 |
| Jegham, S | 1 |
| Biton, B | 1 |
| Leonardon, J | 1 |
| Avenet, P | 1 |
| Sgard, F | 1 |
| Besnard, F | 1 |
| Graham, D | 1 |
| Coste, A | 1 |
| Oblin, A | 1 |
| Curet, O | 1 |
| Voltz, C | 1 |
| Gardes, A | 1 |
| Caille, D | 1 |
| Perrault, G | 1 |
| George, P | 1 |
| Soubrie, P | 1 |
| Scatton, B | 1 |
| Pezze, MA | 1 |
| Ferger, B | 1 |
| Peterson, JD | 1 |
| Wolf, ME | 1 |
| White, FJ | 1 |
| PROUT, CT | 1 |
| Galli, G | 1 |
| Wolffgramm, J | 1 |
| McDougall, SA | 1 |
| Hernandez, RM | 1 |
| Reichel, CM | 1 |
| Farley, CM | 1 |
| Benjamin, E | 1 |
| Salek, S | 1 |
| Peleg-Raibstein, D | 2 |
| Sydekum, E | 2 |
| Wu, HH | 1 |
| Lee, CR | 1 |
| Lin, SK | 1 |
| Yeh, PH | 1 |
| Pan, WH | 1 |
| Dalley, JW | 1 |
| Lääne, K | 1 |
| Theobald, DE | 1 |
| Peña, Y | 1 |
| Bruce, CC | 1 |
| Huszar, AC | 1 |
| Wojcieszek, M | 1 |
| Everitt, BJ | 1 |
| Robbins, TW | 1 |
| Jayaram-Lindström, N | 1 |
| Konstenius, M | 1 |
| Eksborg, S | 1 |
| Beck, O | 1 |
| Hammarberg, A | 1 |
| Schwartz, JM | 1 |
| Ksir, C | 1 |
| Koob, GF | 1 |
| Bloom, FE | 1 |
| Stoff, DM | 1 |
| Jeste, DV | 1 |
| Gillin, JC | 1 |
| Moja, EA | 1 |
| Cohen, L | 1 |
| Stauderman, KA | 1 |
| Wyatt, RJ | 1 |
| Cassens, G | 2 |
| Actor, C | 1 |
| Kling, M | 1 |
| Schildkraut, JJ | 2 |
| Willner, P | 1 |
| Montgomery, T | 1 |
| Johnson, SW | 1 |
| Freedman, R | 1 |
| Sorensen, SM | 1 |
| Deveaugh-Geiss, J | 1 |
| Pandurangi, A | 1 |
| Wise, RA | 1 |
| Munn, E | 1 |
| Schindler, CW | 2 |
| Persico, AM | 2 |
| Uhl, GR | 2 |
| Goldberg, SR | 1 |
| Woolverton, WL | 1 |
| Massey, BW | 1 |
| Winger, G | 1 |
| Patrick, GA | 1 |
| Harris, LS | 1 |
| Brannock, MT | 1 |
| Gonzalez, AM | 1 |
| Surratt, CK | 1 |
| Crippens, D | 1 |
| Camp, DM | 1 |
| Robinson, TE | 1 |
| Lee, TH | 1 |
| Ellinwood, EH | 1 |
| Zhang, H | 1 |
| Connor, DF | 1 |
| Benjamin, S | 1 |
| Ozbayrak, KR | 1 |
| Barr, AM | 3 |
| Phillips, AG | 4 |
| Nolan, EE | 1 |
| Gadow, KD | 1 |
| Sprafkin, J | 1 |
| Fiorino, DF | 1 |
| Cousins, MS | 1 |
| Stamat, HM | 1 |
| de Wit, H | 1 |
| Srisurapanont, M | 1 |
| Jarusuraisin, N | 1 |
| Kittirattanapaiboon, P | 1 |
| Di Ciano, P | 1 |
| Blaha, CD | 1 |
| Zis, AP | 1 |
| Lynch, MA | 2 |
| Leonard, BE | 2 |
| Jenner, P | 1 |
| Pycock, C | 1 |
| Marsden, CD | 1 |
| Branch, MN | 1 |
| Rangaraj, N | 1 |
| Kalant, H | 1 |
| Simpson, DM | 1 |
| Annau, Z | 1 |
| Riffee, WH | 1 |
| Gerald, MC | 1 |
| Smith, RC | 1 |
| Davis, JM | 1 |
| Hitzemann, RJ | 1 |
| Tseng, LF | 1 |
| Hitzemann, BA | 1 |
| Sampath-Khanna, S | 1 |
| Loh, HH | 1 |
| Lucot, JB | 1 |
| McMillan, DE | 1 |
| Leander, JD | 1 |
| Kuruc, A | 1 |
| Orsulak, PJ | 1 |
| Schreiber, H | 1 |
| Bell, R | 1 |
| Conely, L | 1 |
| Kufner, M | 1 |
| Palet, J | 1 |
| Wright, L | 1 |
| Gianutsos, G | 1 |
| Hynes, MD | 1 |
| Drawbaugh, RB | 1 |
| Lal, H | 3 |
| Barrett, RJ | 1 |
| White, DK | 1 |
| Caul, WF | 1 |
| Borowski, TB | 1 |
| Kokkinidis, L | 2 |
| Higgins, ST | 1 |
| Preston, KL | 1 |
| Cone, EJ | 1 |
| Henningfield, JE | 1 |
| Jaffe, JH | 1 |
| Tidey, JW | 1 |
| Miczek, KA | 2 |
| Mucha, RF | 1 |
| Walker, MJ | 1 |
| Fassos, FF | 1 |
| Cappeliez, P | 1 |
| Moore, E | 1 |
| Annett, LE | 1 |
| Ridley, RM | 1 |
| Gamble, SJ | 1 |
| Baker, HF | 1 |
| Leong, GB | 1 |
| Shaner, AL | 1 |
| Silva, JA | 1 |
| Liu, SJ | 1 |
| Wang, RI | 1 |
| Kantak, KM | 1 |
| Zacharko, RM | 1 |
| Anisman, H | 1 |
| Bewley, T | 1 |
| Vogel, GW | 1 |
| Houser, VP | 2 |
| Van Hart, DA | 1 |
| Herz, A | 1 |
| Bläsig, J | 1 |
| Papeschi, R | 1 |
| Tonge, SR | 1 |
| Paulson, GW | 1 |
| Crabtree, JM | 1 |
| Moyer, KE | 1 |
| Puri, SK | 2 |
| Kornetsky, C | 1 |
| Thor, DH | 1 |
| O'Brien, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine: Study 1[NCT00429767] | 16 participants (Anticipated) | Observational | 2007-01-31 | Completed | |||
| A Phase 4, Double-Blind, Multi-Center, Placebo-Controlled, Randomized Withdrawal, Safety and Efficacy Study of SPD489 in Adults Aged 18-55 With Attention-Deficit/Hyperactivity Disorder (ADHD)[NCT00877487] | Phase 4 | 123 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The ADHD-RS consists of 18 items scored on a 4-point scale ranging from 0 (no symptoms) to 3 (severe symptoms) with total score ranging from 0 to 54. (NCT00877487)
Timeframe: Up to 6 weeks
| Intervention | Units on a scale (Least Squares Mean) |
|---|---|
| SPD489 | 1.6 |
| Placebo | 16.8 |
Treatment failure defined as > or equal to 50% increase in the ADHD-RS with adult prompts total score and a > or equal to 2 point increase in the CGI-S score. (NCT00877487)
Timeframe: Up to 6 weeks
| Intervention | Percent of participants (Number) |
|---|---|
| SPD489 | 8.9 |
| Placebo | 75.0 |
CGI-S assesses the severity of the subject's condition on a 7-point scale ranging from 1 (normal, not at all ill) to 7 (among the most extremely ill) (NCT00877487)
Timeframe: Up to 6 weeks
| Intervention | Percent of Participants (Number) | ||||||
|---|---|---|---|---|---|---|---|
| Normal, not at all ill | Borderline mentally ill | Mildly ill | Moderately ill | Markedly ill | Severely ill | Among the most extremely ill | |
| Placebo | 5.0 | 11.7 | 11.7 | 33.3 | 35.0 | 3.3 | 0 |
| SPD489 | 32.1 | 35.7 | 17.9 | 7.1 | 7.1 | 0 | 0 |
4 reviews available for dextroamphetamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Treatment for amphetamine withdrawal.
Topics: Amphetamine; Antidepressive Agents, Tricyclic; Dextroamphetamine; Dibenzocycloheptenes; Dopamine Upt | 2009 |
Treatment for amphetamine withdrawal.
Topics: Amphetamine; Clinical Trials as Topic; Dextroamphetamine; Dopamine Uptake Inhibitors; Humans; Metham | 2001 |
REM deprivation. 3. Dreaming and psychosis.
Topics: Anxiety; Behavior; Depression; Dextroamphetamine; Dreams; Drive; Eye Movements; Hallucinations; Huma | 1968 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
10 trials available for dextroamphetamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Utility of a controlled amphetamine withdrawal paradigm among adults who use methamphetamine: A pilot clinical trial.
Topics: Adult; Amphetamine-Related Disorders; Central Nervous System Stimulants; Dextroamphetamine; Double-B | 2021 |
Randomized controlled trial of dexamphetamine maintenance for the treatment of methamphetamine dependence.
Topics: Adolescent; Adult; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cognitive Behav | 2010 |
Sustained release d-amphetamine reduces cocaine but not 'speedball'-seeking in buprenorphine-maintained volunteers: a test of dual-agonist pharmacotherapy for cocaine/heroin polydrug abusers.
Topics: Adolescent; Adult; Buprenorphine; Choice Behavior; Cocaine; Cocaine-Related Disorders; Delayed-Actio | 2010 |
Maintenance of efficacy of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder: randomized withdrawal design.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; | 2012 |
Naltrexone attenuates the subjective effects of amphetamine in patients with amphetamine dependence.
Topics: Adult; Aging; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cross-Over Studies; | 2008 |
Stimulant medication withdrawal during long-term therapy in children with comorbid attention-deficit hyperactivity disorder and chronic multiple tic disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; | 1999 |
Acute doses of d-amphetamine and bupropion increase cigarette smoking.
Topics: Adult; Affect; Antidepressive Agents, Second-Generation; Bupropion; Central Nervous System Stimulant | 2001 |
Comparative effects of d-amphetamine, l-amphetamine, and methylphenidate on mood in man.
Topics: Adult; Amphetamines; Depression; Dextroamphetamine; Double-Blind Method; Emotions; Euphoria; Female; | 1977 |
Supersensitivity to naloxone following acute morphine pretreatment in humans: behavioral, hormonal and physiological effects.
Topics: Adult; Arousal; Blood Pressure; Body Temperature Regulation; Dextroamphetamine; Dose-Response Relati | 1992 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
71 other studies available for dextroamphetamine and Drug Withdrawal Symptoms
| Article | Year |
|---|---|
Stress and withdrawal from d-amphetamine alter 5-HT2A receptor mRNA expression in the prefrontal cortex.
Topics: Amphetamine-Related Disorders; Animals; Dextroamphetamine; Gene Expression Regulation; Male; Prefron | 2014 |
Influence of calcium channel antagonists on nonsomatic signs of nicotine and D-amphetamine withdrawal in mice.
Topics: Animals; Anxiety; Calcium; Calcium Channel Blockers; Calcium Channels; Depression; Dextroamphetamine | 2014 |
Amphetamine sensitization in mice is sufficient to produce both manic- and depressive-related behaviors as well as changes in the functional connectivity of corticolimbic structures.
Topics: Anhedonia; Animals; Bipolar Disorder; Cerebral Cortex; Dextroamphetamine; Disease Models, Animal; Li | 2015 |
D-Amphetamine withdrawal-induced decreases in brain-derived neurotrophic factor in sprague-dawley rats are reversed by treatment with ketamine.
Topics: Amphetamine-Related Disorders; Animals; Brain-Derived Neurotrophic Factor; Central Nervous System St | 2015 |
Extended access to amphetamine self-administration increases impulsive choice in a delay discounting task in rats.
Topics: Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Choice Behavior; Conditio | 2009 |
Naltrexone attenuates amphetamine-induced locomotor sensitization in the rat.
Topics: Amphetamine-Related Disorders; Animals; Association Learning; Brain; Central Nervous System Stimulan | 2011 |
Acute quetiapine dose-dependently exacerbates anhedonia induced by withdrawal from escalating doses of d-amphetamine.
Topics: Amphetamine-Related Disorders; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous Syst | 2010 |
Chronic amphetamine treatment enhances corticotropin-releasing factor-induced serotonin release in the amygdala.
Topics: Amygdala; Animals; Central Nervous System Stimulants; Corticotropin-Releasing Hormone; Dextroampheta | 2010 |
Characterization of pharmacological and wake-promoting properties of the dopaminergic stimulant sydnocarb in rats.
Topics: Animals; Behavior, Animal; Body Temperature; Central Nervous System Stimulants; Dextroamphetamine; D | 2011 |
Differential regulation of 5-HT2A receptor mRNA expression following withdrawal from a chronic escalating dose regimen of D-amphetamine.
Topics: Animals; Dextroamphetamine; Gene Expression Regulation; Hippocampus; Male; Rats; Rats, Sprague-Dawle | 2011 |
Prepulse inhibition during withdrawal from an escalating dosage schedule of amphetamine.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Central N | 2003 |
SSR591813, a novel selective and partial alpha4beta2 nicotinic receptor agonist with potential as an aid to smoking cessation.
Topics: Animals; Azepines; Behavior, Animal; Body Temperature; Brain; Cardiovascular System; Cells, Cultured | 2003 |
Amphetamine withdrawal modulates FosB expression in mesolimbic dopaminergic target nuclei: effects of different schedules of administration.
Topics: Amygdala; Animals; Brain Chemistry; Central Nervous System Stimulants; Dextroamphetamine; Dopamine; | 2003 |
Impaired DRL 30 performance during amphetamine withdrawal.
Topics: Animals; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Disease Models | 2003 |
REACTIONS TO USE OF AMPHETAMINES AS OBSERVED IN A PSYCHIATRIC HOSPITAL.
Topics: Alcoholism; Amobarbital; Amphetamine; Amphetamines; Barbiturates; Dextroamphetamine; Hospitals, Psyc | 1964 |
Long-term voluntary D-amphetamine consumption and behavioral predictors for subsequent D-amphetamine addiction in rats.
Topics: Aggression; Amphetamine-Related Disorders; Animals; Central Nervous System Stimulants; Choice Behavi | 2004 |
The partial D2-like dopamine receptor agonist terguride acts as a functional antagonist in states of high and low dopaminergic tone: evidence from preweanling rats.
Topics: Animals; Animals, Newborn; Apomorphine; Body Weight; Corpus Striatum; Dextroamphetamine; Dopamine; D | 2005 |
Stimulant-atypical antipsychotic interaction and acute dystonia.
Topics: Adolescent; Aggression; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Bipolar | 2005 |
Withdrawal from repeated amphetamine administration leads to disruption of prepulse inhibition but not to disruption of latent inhibition.
Topics: Acoustic Stimulation; Animals; Avoidance Learning; Central Nervous System Stimulants; Data Interpret | 2006 |
Differential effects on prepulse inhibition of withdrawal from two different repeated administration schedules of amphetamine.
Topics: Animals; Biogenic Monoamines; Body Weight; Central Nervous System Stimulants; Chromatography, High P | 2006 |
A single intrategmental amphetamine exposure induces transient behavioral sensitization in the rats.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Drug Administration Schedule; Male; Rats; Rats, Spragu | 2006 |
Enduring deficits in sustained visual attention during withdrawal of intravenous methylenedioxymethamphetamine self-administration in rats: results from a comparative study with d-amphetamine and methamphetamine.
Topics: Amphetamine-Related Disorders; Amphetamines; Animals; Attention; Attention Deficit Disorder with Hyp | 2007 |
Changes in locomotor response to beta-endorphin microinfusion during and after opiate abstinence syndrome--a proposal for a model of the onset of mania.
Topics: Affective Disorders, Psychotic; Animals; beta-Endorphin; Bipolar Disorder; Dextroamphetamine; Diseas | 1982 |
Behavioral supersensitivity to beta-phenylethylamine after chronic administration of haloperidol.
Topics: Animals; Corpus Striatum; Dextroamphetamine; Haloperidol; Humans; Male; Motor Activity; Phenethylami | 1984 |
Amphetamine withdrawal: effects on threshold of intracranial reinforcement.
Topics: Animals; Behavior, Animal; Depression; Dextroamphetamine; Disease Models, Animal; Humans; Male; Rats | 1981 |
Behavioural changes during withdrawal from desmethylimipramine (DMI). I. Interactions with amphetamine.
Topics: Animals; Anorexia; Desipramine; Dextroamphetamine; Drug Interactions; Eating; Feeding and Eating Dis | 1981 |
Effects of d-amphetamine withdrawal in rats and man.
Topics: Animals; Dextroamphetamine; Humans; Paranoid Disorders; Purkinje Cells; Rats; Substance Withdrawal S | 1983 |
Confusional paranoid psychosis after withdrawal from sympathomimetic amines: two case reports.
Topics: Adult; Aged; Depression; Dextroamphetamine; Diethylpropion; Female; Haloperidol; Humans; Male; Obesi | 1982 |
Withdrawal from chronic amphetamine elevates baseline intracranial self-stimulation thresholds.
Topics: Amphetamine; Animals; Brain; Dextroamphetamine; Dose-Response Relationship, Drug; Hypothalamic Area, | 1995 |
Behavioral assessment of high-dose amphetamine withdrawal: importance of training and testing conditions.
Topics: Animals; Conditioning, Operant; Dextroamphetamine; Habituation, Psychophysiologic; Male; Motor Activ | 1994 |
Evaluation of the abuse liability of aminorex.
Topics: Aminorex; Animals; Arousal; Dextroamphetamine; Discrimination Learning; Female; Infusions, Intraveno | 1994 |
Dopaminergic gene expression during amphetamine withdrawal.
Topics: Animals; Blotting, Northern; Carrier Proteins; Dextroamphetamine; Dopamine; Dopamine Plasma Membrane | 1993 |
Basal extracellular dopamine in the nucleus accumbens during amphetamine withdrawal: a 'no net flux' microdialysis study.
Topics: Animals; Dextroamphetamine; Dopamine; Extracellular Space; Male; Microdialysis; Nucleus Accumbens; R | 1993 |
In vitro extracellular recording from nigral dopamine neurons following continuous d-amphetamine infusion.
Topics: Action Potentials; Animals; Dextroamphetamine; Dopamine; Infusion Pumps, Implantable; Male; Neurons; | 1993 |
Case study: neuroleptic withdrawal dyskinesia exacerbated by ongoing stimulant treatment.
Topics: Antipsychotic Agents; Dextroamphetamine; Diphenhydramine; Fluoxetine; Humans; Male; Mental Disorders | 1995 |
Withdrawal following repeated exposure to d-amphetamine decreases responding for a sucrose solution as measured by a progressive ratio schedule of reinforcement.
Topics: Animals; Central Nervous System Stimulants; Dextroamphetamine; Male; Motivation; Rats; Rats, Long-Ev | 1999 |
Effects of withdrawal from an escalating dose schedule of d-amphetamine on sexual behavior in the male rat.
Topics: Animals; Consummatory Behavior; Dextroamphetamine; Dopamine Uptake Inhibitors; Exploratory Behavior; | 1999 |
Inhibition of dopamine efflux in the rat nucleus accumbens during abstinence after free access to d-amphetamine.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Dextroamphetamine; Dopamine; Dopamine Uptake Inhib | 2002 |
Repeated electroconvulsive shock attenuates the depressive-like effects of d-amphetamine withdrawal on brain reward function in rats.
Topics: Animals; Brain; Central Nervous System Stimulants; Depression; Dextroamphetamine; Electric Stimulati | 2002 |
Effect of chronic amphetamine administration on the behaviour of rats in the open field apparatus: reversal of post-withdrawal depression by two antidepressants.
Topics: Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Dextroamphetamine; Huma | 1978 |
The effect of chronic administration and withdrawal of amphetamine on cerebral dopamine receptor sensitivity.
Topics: Animals; Apomorphine; Behavior, Animal; Biogenic Amines; Brain; Brain Chemistry; Dextroamphetamine; | 1978 |
Consequent events as determinants of drug effects on schedule-controlled behavior: modification of effects of cocaine and d-amphetamine following chronic amphetamine administration.
Topics: Animals; Cocaine; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Drug; Drug T | 1979 |
Effects of ethanol withdrawal, stress and amphetamine on rat brain (Na+ + K+)-ATPase.
Topics: Animals; Brain; Dextroamphetamine; Ethanol; Humans; Male; Rats; Sodium-Potassium-Exchanging ATPase; | 1978 |
Behavioral withdrawal following several psychoactive drugs.
Topics: Animals; Brain; Chlorpromazine; Desipramine; Dextroamphetamine; Electric Stimulation; Humans; Iproni | 1977 |
The effects of chronic administration and withdrawal of (+)-amphetamine on seizure threshold and endogenous catecholamine concentrations and their rates of biosynthesis in mice.
Topics: Animals; Brain; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Dr | 1977 |
Effects of withdrawal from chronic amphetamine intoxication on exploratory and stereotyped behaviors in the rat.
Topics: Animals; Apomorphine; Behavior; Dextroamphetamine; Exploratory Behavior; Humans; Male; Methyltyrosin | 1977 |
Changes in brain gamma-aminobutyric acid concentrations following acute and chronic amphetamine administration and during post amphetamine depression.
Topics: Animals; Brain; Chlorpromazine; Depression; Dextroamphetamine; gamma-Aminobutyric Acid; Humans; Male | 1978 |
The behavioral effects of d-amphetamine alone and in combination with acute and chronic morphine treatments in rats.
Topics: Animals; Behavior, Animal; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationship, Dru | 1979 |
Amphetamine withdrawal: effects on brain levels of MHPG-SO4 in the rat.
Topics: Animals; Brain Chemistry; Dextroamphetamine; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Rats | 1979 |
Diminished reaction to a novel stimulus during amphetamine withdrawal in rats.
Topics: Animals; Behavior, Animal; Dextroamphetamine; Humans; Male; Motor Activity; Rats; Stereotyped Behavi | 1976 |
Paradoxical absence of aggression during naloxone-precipitated morphine withdrawal.
Topics: Aggression; Animals; Apomorphine; Dextroamphetamine; Humans; Male; Morphine Dependence; Naloxone; Ra | 1975 |
Tolerance, withdrawal, and supersensitivity to dopamine mediated cues in a drug-drug discrimination.
Topics: Animals; Cues; Dextroamphetamine; Discrimination, Psychological; Dopamine; Drug Tolerance; Haloperid | 1992 |
Long-term influence of d-amphetamine on mesolimbic brain-stimulation reward: comparison to chronic haloperidol and naloxone effects.
Topics: Animals; Dextroamphetamine; Discrimination Learning; Electric Stimulation; Haloperidol; Limbic Syste | 1992 |
Heightened aggressive behavior during morphine withdrawal: effects of d-amphetamine.
Topics: Aggression; Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Mice; Morphine; Moto | 1992 |
Parker and Radow test of drug withdrawal aversion: opposite effect in rats chronically infused with sufentanil or amphetamine.
Topics: Analgesics, Opioid; Animals; Body Weight; Choice Behavior; Dextroamphetamine; Fentanyl; Infusion Pum | 1990 |
Effects of lithium on an amphetamine animal model of bipolar disorder.
Topics: Animals; Bipolar Disorder; Chlorides; Dextroamphetamine; Disease Models, Animal; Lithium; Lithium Ch | 1990 |
Social withdrawal following amphetamine administration to marmosets.
Topics: Animals; Callitrichinae; Caudate Nucleus; Dextroamphetamine; Injections; Injections, Intramuscular; | 1989 |
Narcolepsy, paranoid psychosis, and analeptic abuse.
Topics: Adult; Dextroamphetamine; Dose-Response Relationship, Drug; Humans; Male; Methylphenidate; Middle Ag | 1989 |
Comparison of the effects of cocaine and d-amphetamine on the pharmacological actions of methadone.
Topics: Analgesia; Animals; Body Temperature; Cocaine; Dextroamphetamine; Drug Interactions; Male; Methadone | 1987 |
Social, motor, and autonomic signs of morphine withdrawal: differential sensitivities to catecholaminergic drugs in mice.
Topics: Animals; Apomorphine; Autonomic Nervous System; Catecholamines; Clonidine; Cocaine; Dextroamphetamin | 1988 |
Amphetamine withdrawal: a behavioral evaluation.
Topics: Acoustic Stimulation; Animals; Dextroamphetamine; Escape Reaction; Injections, Intraperitoneal; Male | 1986 |
Heroin and cocaine addiction.
Topics: Adolescent; Adult; Amphetamine; Barbiturates; Cannabis; Cocaine; Dextroamphetamine; Ethanol; Female; | 1965 |
Effects of withdrawal from chronic amphetamine administration on activity levels of albino rats.
Topics: Animals; Behavior, Animal; Depression, Chemical; Dextroamphetamine; Drinking Behavior; Feeding Behav | 1974 |
Role of catecholaminergic mechanisms in the expression of the morphine abstinence syndrome in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benserazide; Brain Chemistry; Catecholamines; Cocaine; Desip | 1974 |
Noradrenaline and 5-hydroxytryptamine metabolism in six areas of rat brain during post-amphethamine depression.
Topics: Animals; Behavior, Animal; Brain; Depression; Depression, Chemical; Dextroamphetamine; Fluorometry; | 1974 |
Modulation of avoidance behavior in squirrel monkeys after chronic administration and withdrawal of d-amphetamine or -methyl-p-tyrosine.
Topics: Animals; Avoidance Learning; Behavior, Animal; Dextroamphetamine; Factor Analysis, Statistical; Hapl | 1973 |
Movement disorders secondary to drugs.
Topics: Age Factors; Dextroamphetamine; Humans; Metals; Movement Disorders; Myoclonus; Parkinson Disease, Se | 1973 |
Sex differences in fighting and defense induced in rats by shock and dextro-amphetamine during morphine abstinence.
Topics: Aggression; Animals; Behavior, Animal; Dextroamphetamine; Electroshock; Escape Reaction; Female; Hum | 1973 |
Reduced threshold to pain induced aggression specifically related to morphine dependence.
Topics: Aggression; Animals; Dextroamphetamine; Drug Synergism; Electroshock; Ethanol; Humans; Male; Morphin | 1974 |
Amphetamine induced fighting during morphine withdrawal.
Topics: Aggression; Animals; Behavior, Animal; Dextroamphetamine; Humans; Male; Morphine; Rats; Social Behav | 1971 |
Morphine-withdrawal aggression: sensitization by amphetamines.
Topics: Aggression; Amphetamine; Animals; Dextroamphetamine; Humans; Hydroxylamines; Male; Methylphenidate; | 1971 |