Page last updated: 2024-11-07

dextroamphetamine and Dementia

dextroamphetamine has been researched along with Dementia in 6 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.

Research Excerpts

ExcerptRelevanceReference
"Hospital charts were reviewed for 66 medical and surgical patients who received dextroamphetamine or methylphenidate to treat a depressive disorder."3.67Psychostimulant treatment of depressive disorders secondary to medical illness. ( Cassem, NH; Murray, GB; Tesar, GE; Woods, SW, 1986)
" By measuring the brain function using computer period analysis of cerebral biopotentials, dose-efficacy relations were found (in the range of 25-75 mcg) which suggest the bioavailability of LHM at the CNS level."2.64Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram. ( Akpinar, S; Herrmann, WM; Itil, TM, 1975)
"Bereavement after diagnosing AIDS or other HIV disease, psychological symptoms secondary to brain disease and the social consequences of having AIDS all interact to produce a devastating illness where the patient may be intensely grieving, demented and totally rejected by all of society."1.27Psychosocial aspects of AIDS. ( Goldmeier, D, 1987)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huey, ED1
Garcia, C1
Wassermann, EM1
Tierney, MC1
Grafman, J1
Hales, RE1
Hershey, SC1
Itil, TM1
Herrmann, WM1
Akpinar, S1
Goldmeier, D1
Woods, SW1
Tesar, GE1
Murray, GB1
Cassem, NH1
Webb, WL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment Study for Frontotemporal Dementia[NCT00088751]20 participants Observational2004-07-23Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for dextroamphetamine and Dementia

ArticleYear
Psychopharmacologic issues in the diagnosis and treatment of organic mental disorders.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:4

    Topics: Adrenal Cortex Hormones; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Delirium; Dementia;

1984

Trials

2 trials available for dextroamphetamine and Dementia

ArticleYear
Stimulant treatment of frontotemporal dementia in 8 patients.
    The Journal of clinical psychiatry, 2008, Volume: 69, Issue:12

    Topics: Antipsychotic Agents; Central Nervous System Stimulants; Cross-Over Studies; Dementia; Dextroampheta

2008
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:1-2

    Topics: Adolescent; Adult; Aged; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic;

1975

Other Studies

3 other studies available for dextroamphetamine and Dementia

ArticleYear
Psychosocial aspects of AIDS.
    British journal of hospital medicine, 1987, Volume: 37, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Attitude to Health; Brain Diseases; Child; Dementia; Dextroamphe

1987
Psychostimulant treatment of depressive disorders secondary to medical illness.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:1

    Topics: Adjustment Disorders; Adult; Aged; Dementia; Depression; Depressive Disorder; Dextroamphetamine; Fem

1986
The use of psychopharmacological drugs in the aged.
    Geriatrics, 1971, Volume: 26, Issue:6

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Anxiety; Barbiturates; Butyrophenones; Dementia; De

1971