Page last updated: 2024-11-07

dextroamphetamine and Childhood Tic Disorders

dextroamphetamine has been researched along with Childhood Tic Disorders in 15 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Research Excerpts

ExcerptRelevanceReference
"Dextroamphetamine tended to produce more compulsive behaviors, which were also more likely to resemble clinical obsessive-compulsive disorder (OCD), than did methylphenidate."2.67Motor/vocal tics and compulsive behaviors on stimulant drugs: is there a common vulnerability? ( Amass, J; Borcherding, BG; Elia, J; Keysor, CS; Rapoport, JL, 1990)
" In one study, tics limited further dosage increases of methylphenidate."2.58Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders. ( Osland, ST; Pringsheim, T; Steeves, TD, 2018)
" While medications for ADHD are generally well-tolerated, there are common, although less severe, as well as rare but severe adverse events AEs during treatment with ADHD drugs."2.49Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents. ( Banaschewski, T; Buitelaar, J; Coghill, D; Cortese, S; Danckaerts, M; Dittmann, RW; Graham, J; Holtmann, M; Sergeant, J; Taylor, E, 2013)
" Personal or family tic history, medication selection, or dosage was not related to onset of T/D."1.29Tics and dyskinesias associated with stimulant treatment in attention-deficit hyperactivity disorder. ( Adesman, AR; Goldstein, IJ; Lipkin, PH, 1994)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osland, ST1
Steeves, TD1
Pringsheim, T1
Cortese, S1
Holtmann, M1
Banaschewski, T1
Buitelaar, J1
Coghill, D1
Danckaerts, M1
Dittmann, RW1
Graham, J1
Taylor, E1
Sergeant, J1
Kociancic, T1
Reed, MD1
Findling, RL1
Gualtieri, CT2
Evans, RW1
Caine, ED1
Ludlow, CL1
Polinsky, RJ1
Ebert, MH1
Lipkin, PH1
Goldstein, IJ1
Adesman, AR1
Nolan, EE1
Gadow, KD1
Sprafkin, J1
Castellanos, FX1
Levee, JR1
Cohen, MJ1
Rickles, WH1
Borcherding, BG1
Keysor, CS1
Rapoport, JL1
Elia, J1
Amass, J1
Stevenson, RD1
Wolraich, ML1
Weinstein, D1
See, RE1
Ellison, G1
Erenberg, G1
Cruse, RP1
Rothner, AD1
Patterson, DR1
Gadoth, N1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Therapeutic Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Pediatric Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Cohorts (ADHD): a Randomized, Sham-controlled Study.[NCT06069323]80 participants (Anticipated)Interventional2023-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for dextroamphetamine and Childhood Tic Disorders

ArticleYear
Pharmacological treatment for attention deficit hyperactivity disorder (ADHD) in children with comorbid tic disorders.
    The Cochrane database of systematic reviews, 2018, 06-26, Volume: 6

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Central Nervou

2018
Practitioner review: current best practice in the management of adverse events during treatment with ADHD medications in children and adolescents.
    Journal of child psychology and psychiatry, and allied disciplines, 2013, Volume: 54, Issue:3

    Topics: Adolescent; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivity; Blood Pressure

2013
Evaluation of risks associated with short- and long-term psychostimulant therapy for treatment of ADHD in children.
    Expert opinion on drug safety, 2004, Volume: 3, Issue:2

    Topics: Appetite; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; D

2004
Stimulants and tic disorders: from dogma to data.
    Archives of general psychiatry, 1999, Volume: 56, Issue:4

    Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Clinical Trials as

1999
Stimulant medication therapy in the treatment of children with attention deficit hyperactivity disorder.
    Pediatric clinics of North America, 1989, Volume: 36, Issue:5

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Dopamine; Growth; Humans; M

1989

Trials

2 trials available for dextroamphetamine and Childhood Tic Disorders

ArticleYear
Stimulant medication withdrawal during long-term therapy in children with comorbid attention-deficit hyperactivity disorder and chronic multiple tic disorder.
    Pediatrics, 1999, Volume: 103, Issue:4 Pt 1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child;

1999
Motor/vocal tics and compulsive behaviors on stimulant drugs: is there a common vulnerability?
    Psychiatry research, 1990, Volume: 33, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Compulsive Behavior; Dextroamphetamine; Double

1990

Other Studies

8 other studies available for dextroamphetamine and Childhood Tic Disorders

ArticleYear
Carbamazepine-induced tics.
    Developmental medicine and child neurology, 1984, Volume: 26, Issue:4

    Topics: Carbamazepine; Child; Dextroamphetamine; Humans; Male; Methylphenidate; Tic Disorders

1984
Provocative drug testing in Tourette's syndrome: d- and l-amphetamine and haloperidol.
    Journal of the American Academy of Child Psychiatry, 1984, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Amphetamine; Child; Dextroamphetamine; Female; Haloperidol; Humans; Male; Tic Dis

1984
Tics and dyskinesias associated with stimulant treatment in attention-deficit hyperactivity disorder.
    Archives of pediatrics & adolescent medicine, 1994, Volume: 148, Issue:8

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Chronic Disease;

1994
Electromyographic biofeedback for relief of tension in the facial and throat muscles of a woodwind musician.
    Biofeedback and self-regulation, 1976, Volume: 1, Issue:1

    Topics: Adult; Alcoholism; Biofeedback, Psychology; Dextroamphetamine; Electromyography; Facial Muscles; Hum

1976
Delayed appearance of facial tics following chronic fluphenazine administration to guinea pigs.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4

    Topics: Animals; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Dyskinesia, Dr

1989
Gilles de la Tourette's syndrome: effects of stimulant drugs.
    Neurology, 1985, Volume: 35, Issue:9

    Topics: Central Nervous System Stimulants; Child; Dextroamphetamine; Humans; Methylphenidate; Pemoline; Tic

1985
Neuroleptic-induced tics in two hyperactive children.
    The American journal of psychiatry, 1986, Volume: 143, Issue:9

    Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Dextroamphetamine; Halop

1986
[Gilles de la Tourette's syndrome].
    Harefuah, 1974, Apr-01, Volume: 86, Issue:7

    Topics: Brain Chemistry; Catecholamines; Corpus Striatum; Dextroamphetamine; Haloperidol; Humans; Norepineph

1974