Page last updated: 2024-11-07

dextroamphetamine and Cerebral Ischemia

dextroamphetamine has been researched along with Cerebral Ischemia in 6 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Research Excerpts

ExcerptRelevanceReference
"To collect data important for future studies evaluating the effect of dextroamphetamine combined with physiotherapy for improving poststroke motor recovery and to test the efficacy of the approach."9.27Effect of Dextroamphetamine on Poststroke Motor Recovery: A Randomized Clinical Trial. ( Dromerick, AW; Goldstein, LB; Good, DC; Lennihan, L; Pura, J; Rabadi, MJ; Reding, MJ; Samsa, GP, 2018)
"To collect data important for future studies evaluating the effect of dextroamphetamine combined with physiotherapy for improving poststroke motor recovery and to test the efficacy of the approach."5.27Effect of Dextroamphetamine on Poststroke Motor Recovery: A Randomized Clinical Trial. ( Dromerick, AW; Goldstein, LB; Good, DC; Lennihan, L; Pura, J; Rabadi, MJ; Reding, MJ; Samsa, GP, 2018)
" Adverse events, blood pressure, heart rate, body temperature, consciousness level, and functional outcome measures were followed up daily during treatment."2.71Safety of dexamphetamine in acute ischemic stroke: a randomized, double-blind, controlled dose-escalation trial. ( Martinsson, L; Wahlgren, NG, 2003)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldstein, LB1
Lennihan, L1
Rabadi, MJ1
Good, DC1
Reding, MJ1
Dromerick, AW1
Samsa, GP1
Pura, J1
Martinsson, L1
Wahlgren, NG1
Adkins, DL1
Jones, TA1
Barbay, S1
Zoubina, EV1
Dancause, N1
Frost, SB1
Eisner-Janowicz, I1
Stowe, AM1
Plautz, EJ1
Nudo, RJ1
Wishart, TB1
Ijaz, S1
Shuaib, A1
Colbourne, F1
Corbett, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Amphetamine-Enhanced Stroke Recovery[NCT01905371]Phase 299 participants (Actual)Interventional2001-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for dextroamphetamine and Cerebral Ischemia

ArticleYear
Effect of Dextroamphetamine on Poststroke Motor Recovery: A Randomized Clinical Trial.
    JAMA neurology, 2018, 12-01, Volume: 75, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Brain Ischemia; Central Nervous System Stimulants; Combined Modality

2018
Safety of dexamphetamine in acute ischemic stroke: a randomized, double-blind, controlled dose-escalation trial.
    Stroke, 2003, Volume: 34, Issue:2

    Topics: Acute Disease; Administration, Oral; Aged; Blood Pressure; Body Temperature; Brain Ischemia; Conscio

2003

Other Studies

4 other studies available for dextroamphetamine and Cerebral Ischemia

ArticleYear
D-amphetamine enhances skilled reaching after ischemic cortical lesions in rats.
    Neuroscience letters, 2005, Jun-03, Volume: 380, Issue:3

    Topics: Animals; Brain Ischemia; Central Nervous System Stimulants; Cerebral Infarction; Denervation; Dextro

2005
A single injection of D-amphetamine facilitates improvements in motor training following a focal cortical infarct in squirrel monkeys.
    Neurorehabilitation and neural repair, 2006, Volume: 20, Issue:4

    Topics: Animals; Brain Ischemia; Central Nervous System Stimulants; Cerebral Arteries; Cerebral Infarction;

2006
Differential effects of amphetamine and haloperidol on recovery after global forebrain ischemia.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Brain Ischemia; Dextroamphetamine; Disease Models, Animal; Gerbillinae; Haloperidol; Male;

1994
Effects of d-amphetamine on the recovery of function following cerebral ischemic injury.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: Animals; Body Temperature; Brain Ischemia; Dextroamphetamine; Female; Gerbillinae; Hippocampus; Moto

1992