dextroamphetamine has been researched along with Brain Injuries in 16 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 9 (56.25) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senior, HE | 2 |
| McKinlay, L | 2 |
| Nikles, J | 1 |
| Schluter, PJ | 2 |
| Carmont, SA | 2 |
| Waugh, MC | 2 |
| Epps, A | 2 |
| Lloyd, O | 1 |
| Mitchell, GK | 2 |
| Nikles, CJ | 1 |
| Lloyd, OT | 1 |
| Tramontana, MG | 1 |
| Cowan, RL | 1 |
| Zald, D | 1 |
| Prokop, JW | 1 |
| Guillamondegui, O | 1 |
| Darbar, A | 1 |
| Stevens, RT | 1 |
| Siddiqui, AH | 1 |
| McCasland, JS | 1 |
| Hodge, CJ | 1 |
| Barbay, S | 1 |
| Nudo, RJ | 1 |
| Long, D | 1 |
| Young, J | 1 |
| BOELSCHE, A | 1 |
| Chudasama, Y | 1 |
| Nathwani, F | 1 |
| Robbins, TW | 1 |
| Napolitano, E | 1 |
| Elovic, EP | 1 |
| Qureshi, AI | 1 |
| Wagner, AK | 1 |
| Sokoloski, JE | 1 |
| Ren, D | 1 |
| Chen, X | 1 |
| Khan, AS | 1 |
| Zafonte, RD | 1 |
| Michael, AC | 1 |
| Dixon, CE | 1 |
| Dhillon, HS | 1 |
| Dose, JM | 1 |
| Prasad, RM | 1 |
| Bütefisch, CM | 1 |
| Davis, BC | 1 |
| Sawaki, L | 1 |
| Waldvogel, D | 1 |
| Classen, J | 1 |
| Kopylev, L | 1 |
| Cohen, LG | 1 |
| Rosati, DL | 1 |
| Whyte, J | 1 |
| Vaccaro, M | 1 |
| Grieb-Neff, P | 1 |
| Hart, T | 1 |
| Stern, JM | 1 |
| Lipper, S | 1 |
| Tuchman, MM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Utility of Amantadine Hydrochloride in the Treatment of Post-traumatic Irritability: A Randomized, Double-Blind, Placebo-Controlled Trial[NCT00627250] | 76 participants (Actual) | Interventional | 2003-03-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for dextroamphetamine and Brain Injuries
| Article | Year |
|---|---|
The effects of amphetamine on recovery of function in animal models of cerebral injury: a critical appraisal.
Topics: Animals; Brain Injuries; Central Nervous System Stimulants; Dextroamphetamine; Disease Models, Anima | 2009 |
Dexamphetamine treatment in stroke.
Topics: Animals; Brain Injuries; Central Nervous System Stimulants; Dextroamphetamine; Forecasting; Humans; | 2003 |
Pharmacological stimulant treatment of neurocognitive and functional deficits after traumatic and non-traumatic brain injury.
Topics: Amantadine; Animals; Brain Injuries; Bromocriptine; Cognition Disorders; Dextroamphetamine; Humans; | 2005 |
Psychostimulant use in the rehabilitation of individuals with traumatic brain injury.
Topics: Amphetamine; Brain Injuries; Central Nervous System Stimulants; Controlled Clinical Trials as Topic; | 2002 |
5 trials available for dextroamphetamine and Brain Injuries
| Article | Year |
|---|---|
Central nervous system stimulants for secondary attention deficit-hyperactivity disorder after paediatric traumatic brain injury: a rationale and protocol for single patient (n-of-1) multiple cross-over trials.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Bayes Theorem; Brain Injuries; Central Ne | 2013 |
Aggregated n-of-1 trials of central nervous system stimulants versus placebo for paediatric traumatic brain injury--a pilot study.
Topics: Adolescent; Adolescent Behavior; Age Factors; Attention; Attention Deficit Disorder with Hyperactivi | 2014 |
Traumatic brain injury-related attention deficits: treatment outcomes with lisdexamfetamine dimesylate (Vyvanse).
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Brain Injuries; Central Nervous System St | 2014 |
Modulation of use-dependent plasticity by d-amphetamine.
Topics: Adult; Brain Injuries; Central Nervous System Stimulants; Conditioning, Psychological; Dextroampheta | 2002 |
Treatment of chronic post-traumatic organic brain syndrome with dextroamphetamine: first reported case.
Topics: Accidents, Traffic; Adult; Amitriptyline; Brain Injuries; Chlorpromazine; Dextroamphetamine; Drug Th | 1976 |
7 other studies available for dextroamphetamine and Brain Injuries
| Article | Year |
|---|---|
Pharmacological modulation of cortical plasticity following kainic acid lesion in rat barrel cortex.
Topics: Animals; Anticonvulsants; Brain Injuries; Central Nervous System Stimulants; Cerebral Cortex; Dextro | 2008 |
EARLY RECOGNITION OF THE CHILD WITH MINIMAL BRAIN DYSFUNCTION.
Topics: Attention Deficit Disorder with Hyperactivity; Brain; Brain Damage, Chronic; Brain Injuries; Child; | 1965 |
D-Amphetamine remediates attentional performance in rats with dorsal prefrontal lesions.
Topics: Animals; Attention; Behavior, Animal; Brain Injuries; Central Nervous System Stimulants; Conditionin | 2005 |
Controlled cortical impact injury affects dopaminergic transmission in the rat striatum.
Topics: Animals; Behavior, Animal; Blotting, Western; Brain Injuries; Cerebral Cortex; Dextroamphetamine; Do | 2005 |
Amphetamine administration improves neurochemical outcome of lateral fluid percussion brain injury in the rat.
Topics: Animals; Brain Chemistry; Brain Injuries; Central Nervous System Stimulants; Dextroamphetamine; Fatt | 1998 |
Early polyneuropharmacologic intervention in brain injury agitation.
Topics: Adolescent; Adult; Amantadine; Antipsychotic Agents; Brain Injuries; Dextroamphetamine; Drug Adminis | 2002 |
Cranio-cerebral injured patients: A psychiatric clinical description.
Topics: Brain Injuries; Dextroamphetamine; Drug Evaluation; Follow-Up Studies; Humans | 1978 |