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dextroamphetamine and Basal Ganglia Diseases

dextroamphetamine has been researched along with Basal Ganglia Diseases in 6 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Basal Ganglia Diseases: Diseases of the BASAL GANGLIA including the PUTAMEN; GLOBUS PALLIDUS; claustrum; AMYGDALA; and CAUDATE NUCLEUS. DYSKINESIAS (most notably involuntary movements and alterations of the rate of movement) represent the primary clinical manifestations of these disorders. Common etiologies include CEREBROVASCULAR DISORDERS; NEURODEGENERATIVE DISEASES; and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"The effect of various antipsychotic drugs on the blockade of dopaminergic receptors in striatum and limbic forebrain was examined by establishing dose-response curves for the increase in HVA and for the antagonism of d-amphetamine-induced rotation in rats with unilateral lesions of the substantia nigra."1.25On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain. ( Dingell, JV; Hill, H; Robinson, SE; Setler, P; Stawarz, RJ; Sulser, F, 1975)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mena-Segovia, J1
Giordano, M1
Stawarz, RJ1
Hill, H1
Robinson, SE1
Setler, P1
Dingell, JV1
Sulser, F1
Pycock, C1
Tarsy, D1
Marsden, CD1
Rigal, J1
Savelli, A1
Juillet, P1
Weiner, WJ1
Goetz, C1
Westheimer, R1
Klawans, HL1
Bunney, BS1
Aghajanian, GK1

Other Studies

6 other studies available for dextroamphetamine and Basal Ganglia Diseases

ArticleYear
Striatal dopaminergic stimulation produces c-Fos expression in the PPT and an increase in wakefulness.
    Brain research, 2003, Oct-03, Volume: 986, Issue:1-2

    Topics: Animals; Basal Ganglia Diseases; Cholinergic Fibers; Corpus Striatum; Dextroamphetamine; Dopamine; G

2003
On the significance of the increase in homovanillic acid (HVA) caused by antipsychotic drugs in corpus striatum and limbic forebrain.
    Psychopharmacologia, 1975, Aug-21, Volume: 43, Issue:2

    Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Clozapine; Corpus Striatum; D

1975
Inhibition of circling behavior by neuroleptic drugs in mice with unilateral 6-hydroxydopamine lesions of the striatum.
    Psychopharmacologia, 1975, Dec-31, Volume: 45, Issue:2

    Topics: Animals; Apomorphine; Basal Ganglia Diseases; Behavior; Biogenic Amines; Bis(4-Methyl-1-Homopiperazi

1975
[Secondary neurologic manifestations of psychotropic therapeutics. Neurophysiological approach].
    Annales de medecine interne, 1972, Volume: 123, Issue:5

    Topics: Achilles Tendon; Antidepressive Agents; Basal Ganglia Diseases; Butyrophenones; Dextroamphetamine; E

1972
Serotonergic and antiserotonergic influences on amphetamine-induced stereotyped behavior.
    Journal of the neurological sciences, 1973, Volume: 20, Issue:4

    Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Basal Ganglia Diseases; Behavior, Animal; Corpus Striat

1973
Proceedings: Differentiation between neuroleptic antipsychotic properties and side effects by subgroups of dopaminergic neurons.
    Psychopharmacology bulletin, 1974, Volume: 10, Issue:4

    Topics: Animals; Basal Ganglia Diseases; Depression; Dextroamphetamine; Dopamine; Feedback; Humans; Neurons;

1974