dextroamphetamine has been researched along with Anxiety in 55 studies
Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
Excerpt | Relevance | Reference |
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"The purpose of the experiments was to examine the anxiety-related effects of d-amphetamine and nicotine, and the possible involvement of the endocannabinoid system." | 7.75 | Effects of the cannabinoid receptor ligands on anxiety-related effects of d-amphetamine and nicotine in the mouse elevated plus maze test. ( Biala, G; Budzynska, B; Kruk, M, 2009) |
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital." | 7.63 | Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958) |
"Modafinil is a new drug used in the treatment of narcolepsy." | 5.29 | The stimulant effect of modafinil on wakefulness is not associated with an increase in anxiety in mice. A comparison with dexamphetamine. ( Costentin, J; Panissaud, C; Simon, P, 1994) |
"Our results demonstrated that, at the seventh or 14th day of D-amphetamine or nicotine withdrawal, respectively, mice exhibited increased anxiety and depression-like effects, memory impairment and hyperalgesia." | 3.80 | Influence of calcium channel antagonists on nonsomatic signs of nicotine and D-amphetamine withdrawal in mice. ( Biała, G; Budzyńska, B; Kruk-Słomka, M; Michalak, A; Polak, P, 2014) |
"These results demonstrated that similar neural mechanisms were involved in the regulation of nicotine and D-amphetamine anxiety-like behaviour in mice." | 3.75 | Effects of co-administration of bupropion and nicotine or D-amphetamine on the elevated plus maze test in mice. ( Biala, G; Kruk, M, 2009) |
"The purpose of the experiments was to examine the anxiety-related effects of d-amphetamine and nicotine, and the possible involvement of the endocannabinoid system." | 3.75 | Effects of the cannabinoid receptor ligands on anxiety-related effects of d-amphetamine and nicotine in the mouse elevated plus maze test. ( Biala, G; Budzynska, B; Kruk, M, 2009) |
"The purpose of the current experiments was to examine the anxiety-related effects of repeated amphetamine and nicotine administration using the mouse elevated plus maze (EPM)." | 3.74 | Calcium channel antagonists suppress cross-tolerance to the anxiogenic effects of D-amphetamine and nicotine in the mouse elevated plus maze test. ( Biala, G; Kruk, M, 2008) |
", thigmotaxis) was suppressed by anxiolytic agents (diazepam 1-5 mg/kg; chlordiazepoxide 1-10 mg/kg; pentobarbital 1-10 mg/kg), with a relative potency that was similar to their relative potency in the treatment of human anxiety." | 3.67 | Thigmotaxis as a test for anxiolytic activity in rats. ( Fundytus, M; Treit, D, 1988) |
"Seventy unwed pregnant patients in states of mild to moderate depression evidenced by one or more symptoms (tenseness, "nervousness," crying spells, listlessness, fatigue, nausea and vomiting, insomnia and overeating), received informal psychotherapy and a sustained-release capsule combining d-amphetamine sulfate and amobarbital." | 3.63 | Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital. ( CALDWELL, WG; NOWERS, W, 1958) |
"Fenfluramine was particularly effective in alleviating anxiety in patients who were initially higher in anxiety." | 2.64 | Emotional symptomatology in obese patients treated with fenfluramine and dextroamphetamine. ( Fisher, E; Hesbacher, P; Perloff, MM; Rickels, K; Rosenfeld, H, 1976) |
"pramipexole) known to produce compulsive behaviors in humans would increase marble burying." | 1.37 | Pharmacological evaluation of the adequacy of marble burying as an animal model of compulsion and/or anxiety. ( Jimenez-Gomez, C; Osentoski, A; Woods, JH, 2011) |
"Flibanserin is a 5-HT1A agonist that, in contrast to other 5-HT1A receptor agonists, is capable of activating 5-HT1A receptors in frontal cortex." | 1.30 | Behavioral effects of flibanserin (BIMT 17). ( Borsini, F; Brambilla, A; Grippa, N; Pitsikas, N, 1999) |
"Modafinil is a new drug used in the treatment of narcolepsy." | 1.29 | The stimulant effect of modafinil on wakefulness is not associated with an increase in anxiety in mice. A comparison with dexamphetamine. ( Costentin, J; Panissaud, C; Simon, P, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 26 (47.27) | 18.7374 |
1990's | 7 (12.73) | 18.2507 |
2000's | 12 (21.82) | 29.6817 |
2010's | 10 (18.18) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Wolinsky, TD | 1 |
Swanson, CJ | 1 |
Smith, KE | 1 |
Zhong, H | 1 |
Borowsky, B | 1 |
Seeman, P | 1 |
Branchek, T | 1 |
Gerald, CP | 1 |
Valvassori, SS | 1 |
Mariot, E | 1 |
Varela, RB | 1 |
Bavaresco, DV | 1 |
Dal-Pont, GC | 1 |
Ferreira, CL | 1 |
Andersen, ML | 1 |
Tye, SJ | 1 |
Quevedo, J | 1 |
Biała, G | 1 |
Polak, P | 1 |
Michalak, A | 1 |
Kruk-Słomka, M | 1 |
Budzyńska, B | 2 |
Yarosh, HL | 1 |
Meda, SA | 1 |
de Wit, H | 6 |
Hart, AB | 1 |
Pearlson, GD | 1 |
Czopek, A | 1 |
Kołaczkowski, M | 1 |
Bucki, A | 1 |
Byrtus, H | 1 |
Pawłowski, M | 1 |
Kazek, G | 1 |
Bojarski, AJ | 1 |
Piaskowska, A | 1 |
Kalinowska-Tłuścik, J | 1 |
Partyka, A | 1 |
Wesołowska, A | 1 |
Young, S | 1 |
Khondoker, M | 1 |
Emilsson, B | 1 |
Sigurdsson, JF | 1 |
Philipp-Wiegmann, F | 1 |
Baldursson, G | 1 |
Olafsdottir, H | 1 |
Gudjonsson, G | 1 |
Kirkpatrick, MG | 1 |
Goldenson, NI | 1 |
Kapadia, N | 1 |
Kahler, CW | 1 |
Swift, RM | 1 |
McGeary, JE | 1 |
Sussman, S | 1 |
Leventhal, AM | 1 |
Childs, E | 2 |
Biala, G | 3 |
Kruk, M | 3 |
Evenden, J | 1 |
Ross, L | 1 |
Jonak, G | 1 |
Zhou, J | 1 |
Hamidovic, A | 1 |
Conrad, M | 1 |
King, A | 1 |
Jimenez-Gomez, C | 1 |
Osentoski, A | 1 |
Woods, JH | 1 |
Abrial, E | 1 |
Etievant, A | 1 |
Bétry, C | 1 |
Scarna, H | 1 |
Lucas, G | 1 |
Haddjeri, N | 1 |
Lambás-Señas, L | 1 |
Pritchard, LM | 1 |
Van Kempen, TA | 1 |
Zimmerberg, B | 1 |
Asghar, SJ | 1 |
Tanay, VA | 1 |
Baker, GB | 1 |
Greenshaw, A | 1 |
Silverstone, PH | 1 |
Kliethermes, CL | 1 |
Finn, DA | 1 |
Crabbe, JC | 1 |
GRAHN, HV | 1 |
SETTEL, E | 1 |
CALDWELL, WG | 1 |
NOWERS, W | 1 |
FELDMAN, RS | 1 |
LEWIS, E | 1 |
STRINGER, CG | 1 |
Markham, CM | 1 |
Yang, M | 1 |
Blanchard, RJ | 1 |
Blanchard, DC | 1 |
White, TL | 1 |
Grover, VK | 1 |
Pogorelov, VM | 1 |
Lanthorn, TH | 1 |
Savelieva, KV | 1 |
Brody, N | 1 |
Peterson, EA | 1 |
Simon, P | 2 |
Panissaud, C | 2 |
Costentin, J | 2 |
Kavoussi, RJ | 1 |
Coccaro, EF | 1 |
Schmidt, ME | 1 |
Ernst, M | 1 |
Matochik, JA | 1 |
Maisog, JM | 1 |
Pan, BS | 1 |
Zametkin, AJ | 1 |
Potter, WZ | 1 |
Weiss, SM | 1 |
Wadsworth, G | 1 |
Fletcher, A | 1 |
Dourish, CT | 1 |
Rupprecht, R | 1 |
Koch, M | 1 |
Montkowski, A | 1 |
Lancel, M | 1 |
Faulhaber, J | 1 |
Harting, J | 1 |
Spanagel, R | 1 |
Borsini, F | 1 |
Brambilla, A | 1 |
Grippa, N | 1 |
Pitsikas, N | 1 |
Justice, AJ | 1 |
Cole, JO | 1 |
Pope, HG | 1 |
LaBrie, R | 1 |
Ionescu-Pioggia, M | 1 |
Rickels, K | 1 |
Hesbacher, P | 1 |
Fisher, E | 1 |
Perloff, MM | 1 |
Rosenfeld, H | 1 |
Uhlenhuth, EH | 1 |
Oviasu, VO | 1 |
Swerdlow, NR | 1 |
Geyer, MA | 1 |
Vale, WW | 1 |
Koob, GF | 1 |
Shephard, RA | 1 |
Treit, D | 1 |
Fundytus, M | 1 |
Forrest, GL | 1 |
Bortner, TW | 1 |
Bakker, CB | 1 |
Vogel, GW | 1 |
Conners, CK | 1 |
Taylor, E | 1 |
Meo, G | 1 |
Kurtz, MA | 1 |
Fournier, M | 1 |
Winsberg, BG | 2 |
Bialer, I | 3 |
Kupietz, S | 3 |
Tobias, J | 1 |
Press, M | 1 |
Arnold, LE | 1 |
Strobl, D | 1 |
Weisenberg, A | 1 |
Silver, LB | 1 |
Malitz, S | 2 |
Kanzler, M | 2 |
Winsberg, HG | 1 |
Howell, MC | 1 |
Rever, GW | 1 |
Scholl, ML | 1 |
Trowbridge, F | 1 |
Rutledge, A | 1 |
Webb, WL | 1 |
Vogel, JR | 1 |
Beer, B | 1 |
Clody, DE | 1 |
Zeidenberg, P | 1 |
Perel, JM | 1 |
Wharton, RN | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Premenstrual Hormonal and Affective State Evaluation (PHASE) Project[NCT03862469] | 120 participants (Anticipated) | Interventional | 2019-09-26 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for dextroamphetamine and Anxiety
Article | Year |
---|---|
REM deprivation. 3. Dreaming and psychosis.
Topics: Anxiety; Behavior; Depression; Dextroamphetamine; Dreams; Drive; Eye Movements; Hallucinations; Huma | 1968 |
The neurologic learning disability syndrome.
Topics: Anorexia Nervosa; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, C | 1971 |
14 trials available for dextroamphetamine and Anxiety
Article | Year |
---|---|
Cognitive-behavioural therapy in medication-treated adults with attention-deficit/hyperactivity disorder and co-morbid psychopathology: a randomized controlled trial using multi-level analysis.
Topics: Adult; Anxiety; Attention Deficit Disorder with Hyperactivity; Cognition; Cognitive Behavioral Thera | 2015 |
Amphetamine-induced place preference in humans.
Topics: Adult; Affect; Anxiety; Choice Behavior; Conditioning, Psychological; Dextroamphetamine; Double-Blin | 2009 |
Stress-induced changes in mood and cortisol release predict mood effects of amphetamine.
Topics: Adolescent; Adult; Affect; Anger; Anxiety; Central Nervous System Stimulants; Dextroamphetamine; Dou | 2010 |
Relationship of plasma amphetamine levels to physiological, subjective, cognitive and biochemical measures in healthy volunteers.
Topics: Adolescent; Adult; Anxiety; Bipolar Disorder; Blood Pressure; Central Nervous System Stimulants; Cog | 2003 |
Cerebral glucose metabolism during pharmacologic studies: test-retest under placebo conditions.
Topics: Adult; Anxiety; Attention Deficit Disorder with Hyperactivity; Brain; Case-Control Studies; Deoxyglu | 1996 |
Acute effects of d-amphetamine during the early and late follicular phases of the menstrual cycle in women.
Topics: Adolescent; Adult; Analysis of Variance; Anxiety; Behavior; Central Nervous System Stimulants; Dextr | 2000 |
Assessing the subjective effects of stimulants in casual users. A methodology and preliminary results.
Topics: Adult; Anxiety; Caffeine; Central Nervous System Stimulants; Depression; Dextroamphetamine; Emotions | 1978 |
Emotional symptomatology in obese patients treated with fenfluramine and dextroamphetamine.
Topics: Adult; Anxiety; Body Weight; Clinical Trials as Topic; Depression; Dextroamphetamine; Emotions; Fema | 1976 |
The role of personality variables in response to chlorpromazine, dextroamphetamine and placebo.
Topics: Achievement; Adolescent; Adult; Aggression; Anxiety; Chlorpromazine; Clinical Trials as Topic; Dextr | 1967 |
Magnesium pemoline and dextroamphetamine: a controlled study in children with minimal brain dysfunction.
Topics: Analysis of Variance; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Child; Dext | 1972 |
Effects of imipramine and dextroamphetamine on behavior of neuropsychiatrically impaired children.
Topics: Adolescent; Aggression; Anxiety; Brain Damage, Chronic; Child; Child Behavior Disorders; Clinical Tr | 1972 |
Dextroamphetamine and methylphenidate in the treatment of hyperactive-aggressive children.
Topics: Aggression; Anxiety; Attention; Child; Child Behavior Disorders; Child, Preschool; Clinical Trials a | 1974 |
Hyperkinetic adult. Study of the "paradoxical" amphetamine response.
Topics: Adult; Age Factors; Amphetamine; Anxiety; Depression; Dextroamphetamine; Humans; Hyperkinesis; Male; | 1972 |
Are antidepressants better than placebo?
Topics: Adjustment Disorders; Adult; Aged; Amitriptyline; Antidepressive Agents; Anxiety; Clinical Trials as | 1971 |
39 other studies available for dextroamphetamine and Anxiety
Article | Year |
---|---|
The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia.
Topics: Amphetamine; Animals; Anxiety; Behavior, Animal; Catecholamines; Central Nervous System Stimulants; | 2007 |
The role of neurotrophic factors in manic-, anxious- and depressive-like behaviors induced by amphetamine sensitization: Implications to the animal model of bipolar disorder.
Topics: Animals; Anxiety; Behavior, Animal; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Corp | 2019 |
Influence of calcium channel antagonists on nonsomatic signs of nicotine and D-amphetamine withdrawal in mice.
Topics: Animals; Anxiety; Calcium; Calcium Channel Blockers; Calcium Channels; Depression; Dextroamphetamine | 2014 |
Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associations.
Topics: Amphetamine-Related Disorders; Anger; Anxiety; Blood Pressure; Dextroamphetamine; Female; Genome-Wid | 2015 |
Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; De | 2015 |
Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers.
Topics: Adult; Affect; Amphetamine; Anxiety; Arousal; Central Nervous System Stimulants; Dextroamphetamine; | 2016 |
Effects of co-administration of bupropion and nicotine or D-amphetamine on the elevated plus maze test in mice.
Topics: Animals; Animals, Newborn; Antidepressive Agents; Anxiety; Bupropion; Dextroamphetamine; Dose-Respon | 2009 |
A novel operant conflict procedure using incrementing shock intensities to assess the anxiolytic and anxiogenic effects of drugs.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Aripiprazole; Benzodiazepines; Chlordiazepoxide; Conditioning | 2009 |
Effects of the cannabinoid receptor ligands on anxiety-related effects of d-amphetamine and nicotine in the mouse elevated plus maze test.
Topics: Animals; Anxiety; Benzoxazines; Cannabinoid Receptor Agonists; Central Nervous System Stimulants; De | 2009 |
Pharmacological evaluation of the adequacy of marble burying as an animal model of compulsion and/or anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Benzothiazoles; Carbolin | 2011 |
Protein kinase C regulates mood-related behaviors and adult hippocampal cell proliferation in rats.
Topics: Affect; Animals; Antimetabolites; Anxiety; Behavior, Animal; Bipolar Disorder; Bromodeoxyuridine; Ce | 2013 |
Behavioral effects of repeated handling differ in rats reared in social isolation and environmental enrichment.
Topics: Animal Husbandry; Animals; Anxiety; Behavior, Animal; Central Nervous System Stimulants; Dextroamphe | 2013 |
Validation of a modified mirrored chamber sensitive to anxiolytics and anxiogenics in mice.
Topics: Animals; Animals, Outbred Strains; Anti-Anxiety Agents; Anxiety; Carbolines; Dextroamphetamine; Diaz | 2003 |
Use of a d-amphetamine-amobarbital combination as an adjunct to the treatment of carcinoma.
Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Barbiturates; Depression; Depressive Disorder; Dext | 1954 |
Dextro-amphetamine sulfate in mild depression and anxiety.
Topics: Amphetamine; Amphetamines; Anxiety; Anxiety Disorders; Depression; Depressive Disorder; Dextroamphet | 1957 |
Prepartum depression; a study of seventy unwed mothers treated with d-amphetamine sulfate and amobarbital.
Topics: Amobarbital; Amphetamine; Amphetamines; Anxiety; Apathy; Depression; Depressive Disorder; Dextroamph | 1958 |
Response differences of psychotropic drugs in rats during chronic anxiety states.
Topics: Animals; Anxiety; Chlordiazepoxide; Chlorpromazine; Conditioning, Classical; Conditioning, Psycholog | 1962 |
A DEXAMPHETAMINE-BARBITURATE COMBINATION IN ANXIETY-DEPRESSIVE STATES.
Topics: Anxiety; Anxiety Disorders; Barbiturates; Depression; Dextroamphetamine; Humans | 1964 |
Effects of D-amphetamine on defensive behaviors related to fear and anxiety.
Topics: Animals; Anxiety; Avoidance Learning; Cocaine; Dextroamphetamine; Dose-Response Relationship, Drug; | 2006 |
Cortisol effects of D-amphetamine relate to traits of fearlessness and aggression but not anxiety in healthy humans.
Topics: Adolescent; Adult; Aggression; Anxiety; Dextroamphetamine; Fear; Female; Humans; Hydrocortisone; Mal | 2006 |
Use of a platform in an automated open-field to enhance assessment of anxiety-like behaviors in mice.
Topics: Animals; Anxiety; Automation; Crosses, Genetic; Darkness; Dextroamphetamine; Disease Models, Animal; | 2007 |
Calcium channel antagonists suppress cross-tolerance to the anxiogenic effects of D-amphetamine and nicotine in the mouse elevated plus maze test.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Calcium Channel Block | 2008 |
Anxiety, meprobamate, d-amphetamine and the intrasubject variability of word associates.
Topics: Adult; Anxiety; Association; Dextroamphetamine; Drive; Humans; Male; Meprobamate | 1967 |
The stimulant effect of modafinil on wakefulness is not associated with an increase in anxiety in mice. A comparison with dexamphetamine.
Topics: Animals; Anxiety; Benzhydryl Compounds; Central Nervous System Stimulants; Dextroamphetamine; Explor | 1994 |
Anxiogenic-like effects induced by stimulation of dopamine receptors.
Topics: Animals; Anxiety; Benzazepines; Carbolines; Dextroamphetamine; Diazepam; Dopamine Agents; Dopamine A | 1993 |
The amphetamine challenge test correlates with affective lability in healthy volunteers.
Topics: Adult; Anxiety; Biomarkers; Depression; Dextroamphetamine; Double-Blind Method; Female; Humans; Male | 1993 |
Utility of ethological analysis to overcome locomotor confounds in elevated maze models of anxiety.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Data Interpretation, Statistical; Dextroamp | 1998 |
Assessment of neuroleptic-like properties of progesterone.
Topics: Animals; Antipsychotic Agents; Anxiety; Avoidance Learning; Catalepsy; Dextroamphetamine; Dopamine U | 1999 |
Behavioral effects of flibanserin (BIMT 17).
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzimidazoles; Body Temperature; Central N | 1999 |
Evaluating antianxiety agents in humans: experimental paradigms.
Topics: Anxiety; Avoidance Learning; Chlorpromazine; Conditioning, Operant; Dextroamphetamine; Diazepam; Dru | 1977 |
Abuse of stimulant drugs in Nigeria.
Topics: Adolescent; Adult; Anxiety; Caffeine; Dextroamphetamine; Drug Synergism; Female; Humans; Male; Niger | 1976 |
Corticotropin-releasing factor potentiates acoustic startle in rats: blockade by chlordiazepoxide.
Topics: Acoustic Stimulation; Animals; Anxiety; Chlordiazepoxide; Corticotropin-Releasing Hormone; Dextroamp | 1986 |
Chlordiazepoxide and the drinking of water by rats: effects of shock and other suppressive measures.
Topics: Animals; Anxiety; Chlordiazepoxide; Dextroamphetamine; Dose-Response Relationship, Drug; Drinking Be | 1988 |
Thigmotaxis as a test for anxiolytic activity in rats.
Topics: Animals; Anxiety; Behavior, Animal; Dextroamphetamine; Disease Models, Animal; Male; Morphine; Motor | 1988 |
A behavior rating scale for assessing improvement in behaviorally deviant children: a preliminary investigation.
Topics: Adolescent; Aggression; Anxiety; Attention; Child; Child Behavior Disorders; Dextroamphetamine; Diag | 1972 |
Hyperactivity in children: types, diagosis, drug therapy, approaches to management.
Topics: Amphetamine; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chroni | 1972 |
The use of psychopharmacological drugs in the aged.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Anxiety; Barbiturates; Butyrophenones; Dementia; De | 1971 |
A simple and reliable conflict procedure for testing anti-anxiety agents.
Topics: Animals; Anxiety; Behavior, Animal; Chlordiazepoxide; Conflict, Psychological; Dextroamphetamine; Di | 1971 |
Clinical and metabolic studies with imipramine in man.
Topics: Anxiety; Depression; Dextroamphetamine; Female; Humans; Imipramine; Male; Methylphenidate; Psychiatr | 1971 |