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dextroamphetamine and Anesthesia

dextroamphetamine has been researched along with Anesthesia in 16 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"These data support previous PET studies for which constant blood flow was assumed during the bolus PET (11)C-raclopride/AMPH experiment across striatal subregions, while underscoring the importance of considering effects of anesthesia when interpreting in vivo imaging parameters."3.71Sequential H(2)(15)O PET studies in baboons: before and after amphetamine. ( Cantwell, MN; Drevets, WC; Greer, PJ; Mathis, CA; Mazumdar, S; Price, JC; Ruszkiewicz, J; Villemagne, VL; Xu, L, 2002)
" Interestingly, firing rates of neurons in all groups decreased by fivefold or greater under urethane anesthesia, although the relative firing rates between hemispheres were unchanged."3.70Multiple single-unit recordings in the striatum of freely moving animals: effects of apomorphine and D-amphetamine in normal and unilateral 6-hydroxydopamine-lesioned rats. ( Gerhardt, GA; Kish, LJ; Palmer, MR, 1999)
"Modafinil was compared to the indirect dopaminergic drugs, dexamphetamine and methylphenidate, using in vivo differential normal pulse voltammetry with carbon fibre electrodes located in the caudate nucleus to study extracellular catechol level in anaesthetized mice."1.29Lack of pre-synaptic dopaminergic involvement in modafinil activity in anaesthetized mice: in vivo voltammetry studies. ( Boer, C; De Séréville, JE; Duteil, J; Rambert, FA, 1994)
"The spontaneous discharge of the cerebellar Purkinje neuron in urethane-anesthetized rats is used as an indicator of central noradrenergic activity during the acute and chronic administration of d-amphetamine."1.26Effects of acute and chronic amphetamine treatment on Purkinje neuron discharge in rat cerebellum. ( Freedman, R; Marwaha, J, 1980)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199011 (68.75)18.7374
1990's4 (25.00)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Price, JC1
Drevets, WC1
Ruszkiewicz, J1
Greer, PJ1
Villemagne, VL1
Xu, L1
Mazumdar, S1
Cantwell, MN1
Mathis, CA1
JENKINS, LC1
GRAVES, HB1
Menon, MK2
Tseng, LF1
Loh, HH1
Clark, WG2
Kohli, JD1
Goldberg, LI1
Freedman, R1
Marwaha, J1
Vivonia, C1
De Séréville, JE1
Boer, C1
Rambert, FA1
Duteil, J1
Pang, R1
Quartermain, D1
Rosman, E1
Turndorf, H1
Kish, LJ1
Palmer, MR1
Gerhardt, GA1
Mediavilla, A1
Feria, M1
Fernández, JF1
Cagigas, P1
Pazos, A1
Flórez, J1
Bunney, BS1
Walters, JR1
Kuhar, MJ1
Roth, RH1
Aghajanian, GK1
Crespi, F1
Möbius, C1
Morgan, ME1
Vestal, RE1
Warenycia, MW1
McKenzie, GM1
Sutton, ME1
Raskin, LA1
Hemsworth, BA1
Neal, MJ1

Other Studies

16 other studies available for dextroamphetamine and Anesthesia

ArticleYear
Sequential H(2)(15)O PET studies in baboons: before and after amphetamine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002, Volume: 43, Issue:8

    Topics: Anesthesia; Animals; Brain; Carbon Radioisotopes; Cerebrovascular Circulation; Dextroamphetamine; Do

2002
POTENTIAL HAZARDS OF PSYCHOACTIVE DRUGS IN ASSOCIATION WITH ANAESTHESIA.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12

    Topics: Adjuvants, Anesthesia; Amino Alcohols; Amitriptyline; Anesthesia; Antidepressive Agents; Depression;

1965
An electromyographic method for the quantitative evaluation of narcotic analgesics in rats.
    Neuropharmacology, 1980, Volume: 19, Issue:3

    Topics: Analgesics, Opioid; Anesthesia; Animals; Dextroamphetamine; Electromyography; Male; Muscle Contracti

1980
Cardiovascular effects of (--)-cathinone in the anaesthetized dog: comparison with (+)-amphetamine.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:5

    Topics: Alkaloids; Anesthesia; Animals; Blood Pressure; Catecholamines; Dextroamphetamine; Dogs; Heart Rate;

1982
Effects of acute and chronic amphetamine treatment on Purkinje neuron discharge in rat cerebellum.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 212, Issue:3

    Topics: Action Potentials; Anesthesia; Animals; Cerebral Cortex; Dextroamphetamine; Evoked Potentials; Hydro

1980
Interaction between phencyclidine (PCP) and GABA-ergic drugs: clinical implications.
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:1

    Topics: Aminooxyacetic Acid; Anesthesia; Animals; Baclofen; Dextroamphetamine; Diazepam; Drug Interactions;

1980
Lack of pre-synaptic dopaminergic involvement in modafinil activity in anaesthetized mice: in vivo voltammetry studies.
    Neuropharmacology, 1994, Volume: 33, Issue:6

    Topics: alpha-Methyltyrosine; Anesthesia; Animals; Benzhydryl Compounds; Caudate Nucleus; Central Nervous Sy

1994
Effect of propofol on memory in mice.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:1

    Topics: Amnesia, Retrograde; Anesthesia; Animals; Avoidance Learning; Dextroamphetamine; Dose-Response Relat

1993
Multiple single-unit recordings in the striatum of freely moving animals: effects of apomorphine and D-amphetamine in normal and unilateral 6-hydroxydopamine-lesioned rats.
    Brain research, 1999, Jun-26, Volume: 833, Issue:1

    Topics: Anesthesia; Anesthetics, Intravenous; Animals; Apomorphine; Brain Diseases; Corpus Striatum; Dextroa

1999
The stimulatory action of d-amphetamine on the respiratory centre, and its mediation by a central alpha-adrenergic mechanism.
    Neuropharmacology, 1979, Volume: 18, Issue:2

    Topics: Anesthesia; Animals; Decerebrate State; Dextroamphetamine; Drug Interactions; Hemodynamics; Male; Ph

1979
D & L amphetamine stereoisomers: comparative potencies in affecting the firing of central dopaminergic and noradrenergic neurons.
    Psychopharmacology communications, 1975, Volume: 1, Issue:2

    Topics: Amphetamine; Anesthesia; Animals; Cerebral Ventricles; Dextroamphetamine; Dopamine; Neurons; Norepin

1975
In vivo selective monitoring of basal levels of cerebral dopamine using voltammetry with Nafion modified (NA-CRO) carbon fibre micro-electrodes.
    Journal of neuroscience methods, 1992, Volume: 42, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Brain Chemistry; Corpus Striatum; Dextroampheta

1992
Methylxanthine effects on caudate dopamine release as measured by in vivo electrochemistry.
    Life sciences, 1989, Volume: 45, Issue:21

    Topics: Anesthesia; Animals; Caffeine; Caudate Nucleus; Dextroamphetamine; Dopamine; Dose-Response Relations

1989
Excitation of striatal neurons by dexamphetamine is not abolished by either chloral hydrate or urethane anaesthesia.
    Neuropharmacology, 1988, Volume: 27, Issue:12

    Topics: Anesthesia; Animals; Chloral Hydrate; Dextroamphetamine; Male; Neural Conduction; Neurons; Rats; Ure

1988
A behavioral analysis of the effects of amphetamine on play and locomotor activity in the post-weaning rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: Anesthesia; Animals; Dextroamphetamine; Female; Motor Activity; Pregnancy; Rats; Rats, Inbred Strain

1986
The effect of central stimulant drugs on acetylcholine release from rat cerebral cortex.
    British journal of pharmacology, 1968, Volume: 34, Issue:3

    Topics: Acetylcholine; Anesthesia; Animals; Caffeine; Cerebral Cortex; Dextroamphetamine; Electroencephalogr

1968