dextroamphetamine and Aging studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

Excerpt	Relevance	Reference
"The effects of lead acetate and aging on temporally-spaced responding (differential reinforcement of low rate or DRL-20 seconds) were studied."	3.66	Effects of lead on temporally-spaced responding in rats. ( Dietz, DD; Grant, LD; Kimmel, CA; McMillan, DE, 1978)
"Major depressive disorder (MDD) and nicotine dependence are highly comorbid."	2.70	Brain reward system activity in major depression and comorbid nicotine dependence. ( Busto, UE; Cardenas, L; Herrmann, N; Naranjo, CA; Tremblay, LK; Zack, M, 2002)
" AMPH exerted a paradoxical effect on CORT secretion only in maternally deprived subjects while affecting behaviour mainly in deprived female subjects, which showed a generalised shift to the left in the dose-response curve to this drug."	2.41	Paradoxical effects of D-amphetamine in infant and adolescent mice: role of gender and environmental risk factors. ( Cirulli, F; Laviola, G, 2000)
" A treatment history of high AMPH dosage was associated with a marked sensitization of the exploratory behavior in adults, whereas it induced a quite opposite profile in periadolescents."	1.31	Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. ( Laviola, G; Pascucci, T; Pieretti, S, 2001)
" On PND 8, unisexually reared females showed, upon maternal deprivation, a generalized shift to the left in the dose-response curve to AMPH for Crossing behaviour, while on PND 18 AMPH-induced stereotypies were considerably reduced in sexually segregated females, especially following maternal deprivation."	1.30	Sexual segregation in infant mice: behavioural and neuroendocrine responses to d-amphetamine administration. ( Adriani, W; Cirulli, F; Laviola, G, 1997)
"25 mg/kg subcutaneously, at which dosage it is active only on supersensitive receptors of denervated neurons)."	1.29	Comparison between normal developing striatum and developing striatal grafts using drug-induced Fos expression and neuron-specific enolase immunohistochemistry. ( Guerra, MJ; Labandeira-Garcia, JL; Tobio, JP, 1994)
"Similarly, catalepsy induced by (-)-sulpiride (40 mg/kg, i."	1.27	Influence of (-)-sulpiride and YM-09151-2 on stereotyped behavior in chicks and catalepsy in rats. ( Wambebe, C, 1987)
"Nicotine decreased susceptibility to myoclonus and increased susceptibility to clonus, whereas strychnine increased susceptibility to both types of seizure."	1.26	Maturational changes related to dopamine in the effects of d-amphetamine, cocaine, nicotine, and strychnine on seizure susceptibility. ( Alpern, HP; Greer, CA, 1979)
"Morphine pretreatment produced some increase in the running response to amphetamine and to cocaine."	1.25	Increased running response to morphine in morphine-pretreated mice. ( Shuster, L; Webster, GW; Yu, G, 1975)
"The dose-response relationships for three stimulants have been explored."	1.25	The effects of age and illumination on the dose-response curves for three stimulants. ( Isaac, W; Kallman, WM, 1975)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (54.41)	18.7374
1990's	14 (20.59)	18.2507
2000's	11 (16.18)	29.6817
2010's	6 (8.82)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
Whitney, KN	2
Wenger, GR	2
Garrett, DD	1
Nagel, IE	1
Preuschhof, C	1
Burzynska, AZ	1
Marchner, J	1
Wiegert, S	1
Jungehülsing, GJ	1
Nyberg, L	1
Villringer, A	1
Li, SC	1
Heekeren, HR	1
Bäckman, L	1
Lindenberger, U	1
García-Cabrerizo, R	1
García-Fuster, MJ	1
Lander, SS	1
Linder-Shacham, D	1
Gaisler-Salomon, I	1
Torres, OV	1
Tejeda, HA	1
Natividad, LA	1
O'Dell, LE	1
Sonnenschein, B	1
Franklin, KB	1
McDougall, SA	1
Kozanian, OO	1
Greenfield, VY	1
Horn, LR	1
Gutierrez, A	1
Mohd-Yusof, A	1
Castellanos, KA	1
Cardenas, L	1
Tremblay, LK	1
Naranjo, CA	1
Herrmann, N	1
Zack, M	1
Busto, UE	1
Ourednik, J	1
Ourednik, V	1
Lynch, WP	1
Schachner, M	1
Snyder, EY	1
Purdom, MS	2
Stanford, JA	2
Currier, TD	1
Gerhardt, GA	3
NUTTALL, FQ	1
DOE, RP	1
Jayaram-Lindström, N	1
Konstenius, M	1
Eksborg, S	1
Beck, O	1
Hammarberg, A	1
Franck, J	1
Joseph, JA	1
Filburn, CR	1
Roth, GS	1
Jänicke, B	1
Wrobel, D	1
Bauer, RH	3
Dourish, CT	1
Cooper, SJ	1
Raskin, LA	2
Piccirillo, M	1
Alpert, JE	1
Cohen, DJ	1
Shaywitz, BA	1
Messing, RB	1
Rigter, H	1
Nickolson, VJ	1
Hyde, JF	1
Jerussi, TP	1
Concannon, JT	1
Schechter, MD	1
Kilbey, MM	1
Ellinwood, EH	1
Gonzalez, LP	1
Cooper, RL	1
Truex, LL	1
Schmidt, MJ	1
Campbell, BA	1
Reigle, TG	1
Isaac, WL	1
Isaac, W	2
Grilly, DM	1
Simon, BB	1
Labandeira-Garcia, JL	1
Tobio, JP	1
Guerra, MJ	1
Panksepp, J	1
Normansell, L	1
Cox, JF	1
Siviy, SM	1
Wan, RQ	1
Giovanni, A	1
Kafka, SH	1
Corbett, R	1
Cirulli, F	2
Adriani, W	2
Laviola, G	4
Kehoe, P	1
Shoemaker, WJ	1
Triano, L	1
Callahan, M	1
Rappolt, G	1
Poeggeler, B	2
Rassoulpour, A	2
Guidetti, P	2
Wu, HQ	2
Schwarcz, R	2
Chiarotti, F	1
Maloney, RE	1
Ceresoli-Borroni, G	1
Hodgkins, PS	1
Pascucci, T	1
Pieretti, S	1
Zhang, Z	1
Andersen, A	1
Grondin, R	1
Barber, T	1
Avison, R	1
Gerhardt, G	1
Gash, D	1
Mattsson, A	1
Ogren, SO	1
Olson, L	1
Hudick, JP	1
Wajda, IJ	1
Lajtha, A	1
Greer, CA	1
Alpern, HP	1
File, SE	1
Shuster, L	1
Webster, GW	1
Yu, G	1
White, BC	1
Tapp, WN	1
Smith, RC	1
Leelavathi, DE	1
Lauritzen, AM	1
James, RC	1
Franklin, MR	1
Dietz, DD	1
McMillan, DE	1
Grant, LD	1
Kimmel, CA	1
Holmgren, B	1
Urbá-Holmgren, R	1
Valdés, M	1
Oswald, I	1
Kallman, WM	1
Reiter, LW	1
Anderson, GE	1
Laskey, JW	1
Cahill, DF	1
Buwalda, B	1
Koolhaas, JM	1
Bohus, B	1
Jahromi, SS	1
Niesen, C	1
Carlen, PL	1
Trent, F	1
Nakamura, S	1
Tepper, JM	1
Drucker-Colín, R	1
García-Hernández, F	1
Warenycia, MW	1
McKenzie, GM	1
Wambebe, C	1
Feldon, J	1
Weiner, I	1
Hauger, R	1
Hulihan-Giblin, B	1
Paul, SM	1
Halliday, R	1
Callaway, E	1
Naylor, H	1
Gratzinger, P	1
Prael, R	1
Smith, EO	1
Byrd, LD	1
Vaccari, A	1
Chernov, HI	1
Furness, P	1
Partyka, D	1
Plummer, AJ	1
Sainz, A	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Moment-to-moment Neural Variability as a Predictor of Treatment Outcome in Patients With Common Psychiatric Disorders: Major Depressive Disorder, Insomnia and Social Anxiety Disorder[NCT04191811]				150 participants (Anticipated)	Observational	2022-04-01	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Amphetamine modulates brain signal variability and working memory in younger and older adults. Proceedings of the National Academy of Sciences of the United States of America, 2015, Jun-16, Volume: 112, Issue:24 Topics: Adult; Aged; Aging; Brain; Dextroamphetamine; Dopamine; Double-Blind Method; Female; Functional Neur	2015
Brain reward system activity in major depression and comorbid nicotine dependence. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3 Topics: Adolescent; Adult; Affect; Aged; Aging; Aryl Hydrocarbon Hydroxylases; Brain; Carbon Monoxide; Cytoc	2002
Naltrexone attenuates the subjective effects of amphetamine in patients with amphetamine dependence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:8 Topics: Adult; Aging; Amphetamine-Related Disorders; Central Nervous System Stimulants; Cross-Over Studies;	2008

Article	Year
Impulsivity and motor activity in aged, male Ts65Dn mice. Experimental and clinical psychopharmacology, 2013, Volume: 21, Issue:5 Topics: Aging; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dextroamphetamine; Disease	2013
Comparative effects of amphetamine-like psychostimulants on rat hippocampal cell genesis at different developmental ages. Neurotoxicology, 2016, Volume: 56 Topics: Age Factors; Aging; Amphetamine; Animals; Brain-Derived Neurotrophic Factor; Bromodeoxyuridine; Cent	2016
Differential effects of social isolation in adolescent and adult mice on behavior and cortical gene expression. Behavioural brain research, 2017, 01-01, Volume: 316 Topics: Aging; Animals; Avian Proteins; Central Nervous System Stimulants; Dextroamphetamine; Excitatory Ami	2017
Enhanced vulnerability to the rewarding effects of nicotine during the adolescent period of development. Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:4 Topics: Aging; Analysis of Variance; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dext	2008
The rewarding efficacy of brain stimulation and its modulation by dopaminergic drugs in young adult and old BN F344F1 rats. Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:4 Topics: Aging; alpha-Methyltyrosine; Animals; Brain; Brain Chemistry; Conditioning, Operant; Dextroamphetami	2008
One-trial behavioral sensitization in preweanling rats: differential effects of cocaine, methamphetamine, methylphenidate, and D-amphetamine. Psychopharmacology, 2011, Volume: 217, Issue:4 Topics: Aging; Animals; Animals, Suckling; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Dex	2011
Working memory in the aged Ts65Dn mouse, a model for Down syndrome. Behavioural brain research, 2012, Jun-15, Volume: 232, Issue:1 Topics: Aging; Animals; Antidepressive Agents; Central Nervous System Stimulants; Cognition; Conditioning, O	2012
Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nature biotechnology, 2002, Volume: 20, Issue:11 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aging; Animals; Cell Count; Cell Survival; Dextroamphe	2002
Microdialysis studies of D-amphetamine-evoked striatal dopamine overflow in young versus aged F344 rats: effects of concentration and order of administration. Brain research, 2003, Jul-25, Volume: 979, Issue:1-2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Central Nervous System Stimulants; Chromatography, H	2003
Differential effects of post-implantation time on potassium- versus D-amphetamine-evoked dopamine overflow in the striatum of F344 rats. Neuroscience letters, 2003, Sep-11, Volume: 348, Issue:2 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dextroamphetamine; Dopamine; Extracellular Space; Mi	2003
THE ACHILLES REFLEX IN THYROID DISORDERS; A CRITICAL EVALUATION. Annals of internal medicine, 1964, Volume: 61 Topics: Achilles Tendon; Adrenocorticotropic Hormone; Aging; Anemia; Anemia, Pernicious; Aspirin; Cold Tempe	1964
Development of dopamine receptor denervation supersensitivity in the neostriatum of the senescent rat. Life sciences, 1981, Aug-10, Volume: 29, Issue:6 Topics: Adenylyl Cyclases; Aging; Animals; Corpus Striatum; Dextroamphetamine; Ergolines; Female; Male; Moto	1981
Changes in motor activity with age and the effects of pharmacologic treatment. Experimental gerontology, 1984, Volume: 19, Issue:5 Topics: Aging; Animals; Body Weight; Dextroamphetamine; Dihydroergotoxine; Female; Meclofenoxate; Motor Acti	1984
Differential effects of d-amphetamine and scopolamine on the ontogeny of rearing. Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:2 Topics: Aging; Animals; Behavior, Animal; Catecholamines; Dextroamphetamine; Male; Rats; Rats, Inbred Strain	1984
Effects of piribedil and of d-amphetamine on locomotor activity in immature rats. Progress in neuro-psychopharmacology & biological psychiatry, 1984, Volume: 8, Issue:2 Topics: Aging; Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Male; Motor Activity; Piperazin	1984
The influence of environmental variables on amphetamine-induced activity in the preweanling rat. Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2 Topics: Aging; Animals; Climate; Dextroamphetamine; Female; Male; Microclimate; Motor Activity; Rats; Rats,	1983
Amphetamine and maternal behavior: dose response relationships. Psychopharmacology, 1980, Volume: 70, Issue:2 Topics: Aging; Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Female; Maternal Behavior; Moto	1980
Memory consolidation in senescence: effects of CO2, amphetamine and morphine. Neurobiology of aging, 1982,Summer, Volume: 3, Issue:2 Topics: Aging; Animals; Avoidance Learning; Carbon Dioxide; Dextroamphetamine; Female; Memory; Morphine; Rat	1982
Sexual dimorphism in rats with respect to locomotor activity and circling behavior. Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:5 Topics: Aging; Animals; Apomorphine; Dextroamphetamine; Male; Motor Activity; Rats; Rats, Inbred Strains; Ro	1983
Ontogenetic differences in response to d-amphetamine: two-way avoidance, intertrial responses, and locomotor activity. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:2 Topics: Aging; Animals; Avoidance Learning; Catecholamines; Dextroamphetamine; Male; Motor Activity; Periphe	1982
Failure of amphetamine isomers to decrease hyperactivity in developing rats. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:1 Topics: Aging; Amphetamine; Animals; Brain Chemistry; Dextroamphetamine; Dopamine; Dose-Response Relationshi	1982
Differential dopaminergic function in young and old female rats as measured by three behaviors. Communications in psychopharmacology, 1980, Volume: 4, Issue:1 Topics: Aging; Animals; Apomorphine; Behavior, Animal; Dextroamphetamine; Dopamine; Dose-Response Relationsh	1980
3H-amphetamine concentrations in the brains of young and aged rats: implications for assessment of drug effects in aged animals. Neurobiology of aging, 1980,Summer, Volume: 1, Issue:1 Topics: Adipose Tissue; Aging; Amphetamine; Animals; Brain; Dextroamphetamine; Humans; Liver; Male; Motor Ac	1980
Ontogeny of amphetamine anorexia in rats: a behavioral analysis. Journal of comparative and physiological psychology, 1981, Volume: 95, Issue:3 Topics: Aging; Animals; Dextroamphetamine; Dose-Response Relationship, Drug; Eating; Female; Male; Pregnancy	1981
Behavioral and neurochemical interactions of dextroamphetamine and methylphenidate in rats. Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:7 Topics: Aging; Animals; Behavior, Animal; Brain Chemistry; Catecholamines; Dextroamphetamine; Dose-Response	1981
The effects of l-, d-, and parahydroxy-amphetamine on locomotor activity and wall climbing in rats of different ages. Pharmacology, biochemistry, and behavior, 1980, Volume: 13, Issue:2 Topics: Aging; Amphetamine; Amphetamines; Animals; Catecholamines; Dextroamphetamine; Dose-Response Relation	1980
Differential effects of d-amphetamine on vigilance in younger and older male rats. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3 Topics: Aging; Animals; Arousal; Conditioning, Operant; Cues; Dextroamphetamine; Dose-Response Relationship,	1994
Comparison between normal developing striatum and developing striatal grafts using drug-induced Fos expression and neuron-specific enolase immunohistochemistry. Neuroscience, 1994, Volume: 60, Issue:2 Topics: Aging; Animals; Apomorphine; Brain Tissue Transplantation; Cell Differentiation; Corpus Striatum; De	1994
Effects of neonatal decortication on the social play of juvenile rats. Physiology & behavior, 1994, Volume: 56, Issue:3 Topics: Aging; Animals; Animals, Newborn; Appetitive Behavior; Brain Mapping; Cerebral Cortex; Cerebral Deco	1994
Neonatal hippocampal lesions induced hyperresponsiveness to amphetamine: behavioral and in vivo microdialysis studies. Behavioural brain research, 1996, Volume: 78, Issue:2 Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain Chemistry; Central Nervous System Stimulan	1996
Sexual segregation in infant mice: behavioural and neuroendocrine responses to d-amphetamine administration. Psychopharmacology, 1997, Volume: 134, Issue:2 Topics: Aging; Animals; Behavior, Animal; Body Weight; Central Nervous System Stimulants; Corticosterone; De	1997
Adult rats stressed as neonates show exaggerated behavioral responses to both pharmacological and environmental challenges. Behavioral neuroscience, 1998, Volume: 112, Issue:1 Topics: Aging; Animals; Animals, Newborn; Arousal; Brain; Dextroamphetamine; Female; Male; Maternal Deprivat	1998
Dopaminergic control of kynurenate levels and N-methyl-D-aspartate toxicity in the developing rat striatum. Developmental neuroscience, 1998, Volume: 20, Issue:2-3 Topics: Aging; Animals; Animals, Newborn; Corpus Striatum; Dextroamphetamine; Dopamine; Dopamine Agents; Dop	1998
Elevated novelty seeking and peculiar d-amphetamine sensitization in periadolescent mice compared with adult mice. Behavioral neuroscience, 1998, Volume: 112, Issue:5 Topics: Aging; Analysis of Variance; Animals; Body Weight; Central Nervous System Stimulants; Corticosterone	1998
Microdialysis studies of basal levels and stimulus-evoked overflow of dopamine and metabolites in the striatum of young and aged Fischer 344 rats. Brain research, 1999, Jan-16, Volume: 816, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Corpus Striatum; Dextroampheta	1999
Modulation and function of kynurenic acid in the immature rat brain. Advances in experimental medicine and biology, 1999, Volume: 467 Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; Animals; Brain; Dextroamphetamine; Enzyme Inhibitors; E	1999
Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Caud	2001
Pharmacological MRI mapping of age-associated changes in basal ganglia circuitry of awake rhesus monkeys. NeuroImage, 2001, Volume: 14, Issue:5 Topics: Aging; Animals; Apomorphine; Basal Ganglia; Brain Mapping; Dextroamphetamine; Female; Macaca mulatta	2001
Facilitation of dopamine-mediated locomotor activity in adult rats following cholinergic denervation. Experimental neurology, 2002, Volume: 174, Issue:1 Topics: Aging; Animals; Apomorphine; Behavior, Animal; Cerebellum; Cerebral Cortex; Cholinergic Fibers; Dene	2002
The amphetamine-induced inhibition of dopamine biosynthesis in rat striatum. European journal of pharmacology, 1976, Volume: 35, Issue:2 Topics: Aging; Animals; Animals, Newborn; Corpus Striatum; Depression, Chemical; Dextroamphetamine; Dopamine	1976
Maturational changes related to dopamine in the effects of d-amphetamine, cocaine, nicotine, and strychnine on seizure susceptibility. Psychopharmacology, 1979, Volume: 64, Issue:3 Topics: Aging; Animals; Cocaine; Dextroamphetamine; Dopamine; Mice; Myoclonus; Nicotine; Seizures; Strychnin	1979
Exploration in immature rats: effects of drugs. Developmental psychobiology, 1978, Volume: 11, Issue:5 Topics: Aging; Animals; Dextroamphetamine; Exploratory Behavior; Fenclonine; Humans; Male; Rats; Scopolamine	1978
Increased running response to morphine in morphine-pretreated mice. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1 Topics: Aging; Analgesics, Opioid; Animals; Animals, Newborn; Cocaine; Dextroamphetamine; Dose-Response Rela	1975
Unilateral catecholamine depletion of the corpus striatum and amphetamine-induced turning: an ontogenetic study. Psychopharmacology, 1977, Jul-18, Volume: 53, Issue:2 Topics: Aging; Animals; Behavior; Catecholamines; Corpus Striatum; Dextroamphetamine; Drug Interactions; Fem	1977
Behavioral effects of dopamine agonists increase with age. Communications in psychopharmacology, 1978, Volume: 2, Issue:1 Topics: Aging; Animals; Apomorphine; Behavior; Dextroamphetamine; Dopamine; Humans; Rats; Rats, Inbred F344;	1978
The triphasic amphetamine lethal dose curve in mice and its possible relationship to drug metabolism. Toxicology and applied pharmacology, 1978, Volume: 44, Issue:1 Topics: Aging; Amphetamine; Animals; Anticonvulsants; Dextroamphetamine; Hexobarbital; In Vitro Techniques;	1978
Effects of lead on temporally-spaced responding in rats. Drug and chemical toxicology, 1978, Volume: 1, Issue:4 Topics: Aging; Animals; Animals, Newborn; Conditioning, Operant; Dextroamphetamine; Dose-Response Relationsh	1978
Spontaneous and amphetamine induced head-shaking in infant rats. Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:1 Topics: Aging; Animals; Animals, Newborn; Behavior; Dextroamphetamine; Dose-Response Relationship, Drug; Fem	1976
Psychological medicine. Sleep difficulties. British medical journal, 1975, Mar-08, Volume: 1, Issue:5957 Topics: Aging; Beverages; Dextroamphetamine; Dreams; Female; Humans; Hypnotics and Sedatives; Male; Mental D	1975
The effects of age and illumination on the dose-response curves for three stimulants. Psychopharmacologia, 1975, Volume: 40, Issue:4 Topics: Adaptation, Psychological; Aging; Animals; Arousal; Caffeine; Darkness; Dextroamphetamine; Dose-Resp	1975
Developmental and behavioral changes in the rat during chronic exposure to lead. Environmental health perspectives, 1975, Volume: 12 Topics: Aging; Animals; Behavior, Animal; Dextroamphetamine; Exploratory Behavior; Eye; Female; Growth; Lead	1975
Behavioral and cardiac responses to mild stress in young and aged rats: effects of amphetamine and vasopressin. Physiology & behavior, 1992, Volume: 51, Issue:2 Topics: Aging; Animals; Arginine Vasopressin; Arousal; Autonomic Nervous System; Behavior, Animal; Dextroamp	1992
Amphetamine actions on pre- and postpubertal rat hippocampal dentate granule neurons. Brain research, 1991, Aug-09, Volume: 556, Issue:1 Topics: Aging; Animals; Atenolol; Calcium Channels; Cocaine; Dextroamphetamine; Evoked Potentials; Haloperid	1991
Amphetamine exerts anomalous effects on dopaminergic neurons in neonatal rats in vivo. European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3 Topics: Aging; Animals; Animals, Newborn; Apomorphine; Corpus Striatum; Dextroamphetamine; Dopamine; Electri	1991
A new motor test sensitive to aging and dopaminergic function. Journal of neuroscience methods, 1991, Volume: 39, Issue:2 Topics: Aging; Animals; Body Weight; Dextroamphetamine; Dopamine; Haloperidol; Levodopa; Male; Motor Activit	1991
Decreases in behavioral and striatal neuronal responses to dexamphetamine with aging. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2 Topics: Aging; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Male; Motor Activity; Rats	1989
Influence of (-)-sulpiride and YM-09151-2 on stereotyped behavior in chicks and catalepsy in rats. Japanese journal of pharmacology, 1987, Volume: 43, Issue:2 Topics: Aging; Animals; Antipsychotic Agents; Benzamides; Catalepsy; Chickens; Dextroamphetamine; Fenclonine	1987
Long-term attentional deficit in nonhandled males: possible involvement of the dopaminergic system. Psychopharmacology, 1988, Volume: 95, Issue:2 Topics: Aging; Animals; Attention; Dextroamphetamine; Female; Haloperidol; Handling, Psychological; Male; Ra	1988
Increased number of hypothalamic [3H] (+)-amphetamine binding sites in genetically obese (ob/ob) mice. Neuropharmacology, 1986, Volume: 25, Issue:3 Topics: Aging; Animals; Blood Glucose; Carrier Proteins; Dextroamphetamine; Hypothalamus; Male; Mice; Mice,	1986
The effects of stimulant drugs on information processing in elderly adults. Journal of gerontology, 1986, Volume: 41, Issue:6 Topics: Adult; Aged; Aging; Cognition; Dextroamphetamine; Female; Humans; Intelligence; Male; Methylphenidat	1986
d-Amphetamine induced changes in social interaction patterns. Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:1 Topics: Aggression; Aging; Animals; Dextroamphetamine; Humans; Macaca; Male; Social Behavior	1985
Hyposensitivity ot 5-hydroxytryptamine in the isolated stomach fundus of the newborn rat. II. Amphetamine and receptor deficit. Biochemical pharmacology, 1968, Volume: 17, Issue:12 Topics: Aging; Amphetamine; Animals; Animals, Newborn; Dextroamphetamine; Female; Male; Muscle, Smooth; Rats	1968
Age, confinement and aggregation as factors in amphetamine group toxicity in mice. The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:2 Topics: Aging; Animals; Dextroamphetamine; Environment; Mice; Stress, Physiological	1966
Hyperkinetic disease of children: diagnosis and therapy. Diseases of the nervous system, 1966, Volume: 7 Suppl, Issue:7 Topics: Adolescent; Adult; Aging; Brain Damage, Chronic; Child; Chlordiazepoxide; Dextroamphetamine; Humans;	1966

dextroamphetamine and Aging

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