Page last updated: 2024-11-07

dextroamphetamine and Addiction, Opioid

dextroamphetamine has been researched along with Addiction, Opioid in 10 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Research Excerpts

ExcerptRelevanceReference
"While all have the goal of treating pain while mitigating misuse and abuse, there are different technologies utilized to impart the abuse-deterrent properties."2.48Abuse-deterrent formulations, an evolving technology against the abuse and misuse of opioid analgesics. ( Schaeffer, T, 2012)
" dosing and dispensation protocols) can be adjusted to allow for various scenarios (e."1.62Exploring the effectiveness of dextroamphetamine for the treatment of stimulant use disorder: a qualitative study with patients receiving injectable opioid agonist treatment. ( Bojanczyk-Shibata, A; Harrison, S; Jun, J; Lock, K; MacDonald, S; Marchand, K; Marsh, DC; Oviedo-Joekes, E; Palis, H; Peachey, GS; Schechter, MT; Westfall, J, 2021)
"Dextroamphetamine was prescribed to a 51-year-old male who was diagnosed with concurrent opioid and stimulant use disorder in an injectable opioid agonist treatment clinic in Vancouver, Canada."1.62Use of sustained release dextroamphetamine for the treatment of stimulant use disorder in the setting of injectable opioid agonist treatment in Canada: a case report. ( Jun, J; MacDonald, S; Oviedo-Joekes, E; Palis, H, 2021)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (30.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Palis, H2
Marchand, K1
Peachey, GS1
Westfall, J1
Lock, K1
MacDonald, S2
Jun, J2
Bojanczyk-Shibata, A1
Harrison, S1
Marsh, DC1
Schechter, MT1
Oviedo-Joekes, E2
Blanken, P1
Nuijten, M1
van den Brink, W1
Hendriks, VM1
Vohra, V1
King, A1
Daviskiba, S1
Reed, B1
Rockhill, S1
Kern, P1
Dean, D1
Jordan, CJ1
Cao, J1
Newman, AH1
Xi, ZX1
Greenwald, MK1
Lundahl, LH1
Steinmiller, CL1
Schaeffer, T1
Charnaud, B1
Griffiths, V1
Higgins, ST1
Preston, KL1
Cone, EJ1
Henningfield, JE2
Jaffe, JH1
Lamb, RJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of 24 Weeks Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder With Comorbid Opioid Use Disorder - A Multicenter Randomized, Double-blind, Placebo-controlled Study[NCT05529927]Phase 2204 participants (Anticipated)Interventional2024-03-31Not yet recruiting
Reducing Cocaine/Heroin Abuse With SR-Amphetamine and Buprenorphine: Study 1[NCT00429767]16 participants (Anticipated)Observational2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dextroamphetamine and Addiction, Opioid

ArticleYear
Progress in agonist therapy for substance use disorders: Lessons learned from methadone and buprenorphine.
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: Analgesics, Opioid; Buprenorphine; Central Nervous System Stimulants; Cocaine-Related Disorders; Dex

2019
Abuse-deterrent formulations, an evolving technology against the abuse and misuse of opioid analgesics.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2012, Volume: 8, Issue:4

    Topics: Analgesics, Opioid; Buprenorphine; Chemistry, Pharmaceutical; Dextroamphetamine; Humans; Lisdexamfet

2012

Trials

3 trials available for dextroamphetamine and Addiction, Opioid

ArticleYear
Clinical effects beyond cocaine use of sustained-release dexamphetamine for the treatment of cocaine dependent patients with comorbid opioid dependence: secondary analysis of a double-blind, placebo-controlled randomized trial.
    Addiction (Abingdon, England), 2020, Volume: 115, Issue:5

    Topics: Adult; Central Nervous System Stimulants; Cocaine-Related Disorders; Delayed-Action Preparations; De

2020
Sustained release d-amphetamine reduces cocaine but not 'speedball'-seeking in buprenorphine-maintained volunteers: a test of dual-agonist pharmacotherapy for cocaine/heroin polydrug abusers.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:13

    Topics: Adolescent; Adult; Buprenorphine; Choice Behavior; Cocaine; Cocaine-Related Disorders; Delayed-Actio

2010
Supersensitivity to naloxone following acute morphine pretreatment in humans: behavioral, hormonal and physiological effects.
    Drug and alcohol dependence, 1992, Volume: 30, Issue:1

    Topics: Adult; Arousal; Blood Pressure; Body Temperature Regulation; Dextroamphetamine; Dose-Response Relati

1992

Other Studies

5 other studies available for dextroamphetamine and Addiction, Opioid

ArticleYear
Exploring the effectiveness of dextroamphetamine for the treatment of stimulant use disorder: a qualitative study with patients receiving injectable opioid agonist treatment.
    Substance abuse treatment, prevention, and policy, 2021, 09-16, Volume: 16, Issue:1

    Topics: Analgesics, Opioid; Central Nervous System Stimulants; Dextroamphetamine; Humans; Methamphetamine; O

2021
Stimulant storm - state health department psychostimulant age-adjusted mortality rate correlates with psychostimulant-based Michigan Poison Center case exposures over time.
    Clinical toxicology (Philadelphia, Pa.), 2021, Volume: 59, Issue:8

    Topics: Adult; Amphetamine; Central Nervous System Stimulants; Dextroamphetamine; Drug Overdose; Female; Hum

2021
Use of sustained release dextroamphetamine for the treatment of stimulant use disorder in the setting of injectable opioid agonist treatment in Canada: a case report.
    Harm reduction journal, 2021, 05-20, Volume: 18, Issue:1

    Topics: Analgesics, Opioid; Canada; Central Nervous System Stimulants; Delayed-Action Preparations; Dextroam

2021
Levels of intravenous drug misuse among clients prescribed oral dexamphetamine or oral methadone: a comparison.
    Drug and alcohol dependence, 1998, Sep-01, Volume: 52, Issue:1

    Topics: Adult; Dextroamphetamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Female; Huma

1998
Human d-amphetamine drug discrimination: testing with d-amphetamine and hydromorphone.
    NIDA research monograph, 1989, Volume: 95

    Topics: Adult; Arousal; Dextroamphetamine; Discrimination Learning; Dose-Response Relationship, Drug; Humans

1989