Page last updated: 2024-11-07

dextroamphetamine and Acquired Immunodeficiency Syndrome

dextroamphetamine has been researched along with Acquired Immunodeficiency Syndrome in 5 studies

Dextroamphetamine: The d-form of AMPHETAMINE. It is a central nervous system stimulant and a sympathomimetic. It has also been used in the treatment of narcolepsy and of attention deficit disorders and hyperactivity in children. Dextroamphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulating release of monamines, and inhibiting monoamine oxidase. It is also a drug of abuse and a psychotomimetic.
(S)-amphetamine : A 1-phenylpropan-2-amine that has S configuration.

Acquired Immunodeficiency Syndrome: An acquired defect of cellular immunity associated with infection by the human immunodeficiency virus (HIV), a CD4-positive T-lymphocyte count under 200 cells/microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms. Clinical manifestations also include emaciation (wasting) and dementia. These elements reflect criteria for AIDS as defined by the CDC in 1993.

Research Excerpts

ExcerptRelevanceReference
"Seven patients with AIDS-related cognitive and emotional deficits had neuropsychologic testing and then were treated with methylphenidate or dextroamphetamine in individualized doses."2.67Central nervous system stimulants as symptomatic treatments for AIDS-related neuropsychiatric impairment. ( Angrist, B; d'Hollosy, M; Diamond, G; Sanfilipo, M; Satriano, J; Simberkoff, M; Weinreb, H, 1992)
" Twenty-four men entered the study, 18 of 19 (95%) patients who completed at least 6 weeks of treatment reported substantial improvement with regard to both mood and energy at a median dosage of 10 mg/day."1.30Dextroamphetamine as a treatment for depression and low energy in AIDS patients: a pilot study. ( Rabkin, JG; Rabkin, R; Wagner, GJ, 1997)
"Bereavement after diagnosing AIDS or other HIV disease, psychological symptoms secondary to brain disease and the social consequences of having AIDS all interact to produce a devastating illness where the patient may be intensely grieving, demented and totally rejected by all of society."1.27Psychosocial aspects of AIDS. ( Goldmeier, D, 1987)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rabkin, JG2
Rabkin, R2
Wagner, G1
Wagner, GJ1
Angrist, B1
d'Hollosy, M1
Sanfilipo, M1
Satriano, J1
Diamond, G1
Simberkoff, M1
Weinreb, H1
Fernandez, F1
Levy, JK1
Galizzi, H1
Goldmeier, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Conscious Dying/Conscious Living: Ketamine-Assisted Psychotherapy (KAP) for Patients at End of Life-A Pilot Study for Palliative and Hospice Care[NCT05214417]Phase 2120 participants (Anticipated)Interventional2022-05-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for dextroamphetamine and Acquired Immunodeficiency Syndrome

ArticleYear
Effects of fluoxetine on mood and immune status in depressed patients with HIV illness.
    The Journal of clinical psychiatry, 1994, Volume: 55, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Affect; Aged; CD4-Positive T-Lymphocytes; Dep

1994
Central nervous system stimulants as symptomatic treatments for AIDS-related neuropsychiatric impairment.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Dextroamphetamine; Humans; Male; Mental Disorders; Methyl

1992

Other Studies

3 other studies available for dextroamphetamine and Acquired Immunodeficiency Syndrome

ArticleYear
Dextroamphetamine as a treatment for depression and low energy in AIDS patients: a pilot study.
    Journal of psychosomatic research, 1997, Volume: 42, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; CD4 Lymphocyte Count; Central Nervous S

1997
Response of HIV-related depression to psychostimulants: case reports.
    Hospital & community psychiatry, 1988, Volume: 39, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Depressive Disorder; Dextroamphetamine; Humans; Male; Met

1988
Psychosocial aspects of AIDS.
    British journal of hospital medicine, 1987, Volume: 37, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Attitude to Health; Brain Diseases; Child; Dementia; Dextroamphe

1987