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dexmedetomidine and Spinal Cord Injuries

dexmedetomidine has been researched along with Spinal Cord Injuries in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's11 (68.75)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Chen, WC; He, HF; Li, W; Lin, YL; Liu, WF; Liu, YB; Xu, CJ1
Chen, T; Kang, G; Li, M; Luo, X; Qiu, X; Yan, L; Zhao, K1
Beattie, MS; Bresnahan, JC; Chang, YW; Du, Q; Gao, J; Lin, A; Maze, M; Niu, X; Pan, JZ; Sun, W; Sun, Y; Sun, Z; Wang, G; Xiao, Z1
Feng, WZ; He, FY; Shao, HY; Xu, W; Zhang, YR; Zhong, J1
He, H; He, X; Lin, W; Wang, S; Zhou, Y; Zhuang, J1
Jiao, ZH; Wang, L; Wang, WG; Xu, ZW; Xue, B1
Celik, F; Evliyaoğlu, O; Fırat, U; Göçmez, C; Guzel, A; Kamaşak, K; Tokgoz, O; Tufek, A1
Ji, D; Li, H; Li, SS; Xiong, YC; Xu, H; Yang, JL; Zhang, WS; Zhang, YQ; Zhou, YL1
Lee, KH1
Bell, MT; Cleveland, JC; Foley, LS; Freeman, KA; Fullerton, DA; Herson, PS; Mares, JM; Meng, X; Puskas, F; Reece, TB; Weyant, MJ1
Hai-Chen, C; Ji-Shun, N; Shou-Shi, W; Ting-Ting, S1
Feng, J; Gu, X; Hou, B; Lei, Y; Liu, Y; Ma, Z; Rong, H; Sun, R; Sun, Y; Wu, H; Zhang, W; Zhang, Z; Zhao, Z1
Altunbaş, K; Aslan, A; Baş, O; Buyukokuroglu, ME; Cemek, M; Cosar, M; Ela, Y; Eser, O; Fidan, H1
Acikgoz, S; Bektas, S; Can, M; Gul, S; Hanci, V1
Acikgoz, B; Acikgoz, S; Ankarali, H; Bahadir, B; Bektas, S; Gul, S; Hanci, V; Kalayci, M1
Fitzgerald, M; Walker, SM1

Other Studies

16 other study(ies) available for dexmedetomidine and Spinal Cord Injuries

ArticleYear
Dexmedetomidine alleviates traumatic spinal cord injury in rats via inhibiting apoptosis induced by endoplasmic reticulum stress.
    Neurological research, 2022, Volume: 44, Issue:3

    Topics: Animals; Apoptosis; Dexmedetomidine; Disease Models, Animal; Endoplasmic Reticulum Stress; Male; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries

2022
Dexmedetomidine promotes spinal cord injury repairing via activating Nrf2/HO-1 signaling pathway.
    Journal of neurosurgical sciences, 2020, Volume: 64, Issue:6

    Topics: Animals; Dexmedetomidine; Heme Oxygenase (Decyclizing); NF-E2-Related Factor 2; Rats; Signal Transduction; Spinal Cord; Spinal Cord Injuries

2020
Dexmedetomidine modulates neuroinflammation and improves outcome via alpha2-adrenergic receptor signaling after rat spinal cord injury.
    British journal of anaesthesia, 2019, Volume: 123, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cells, Cultured; Dexmedetomidine; Disease Models, Animal; Female; Inflammation; Microglia; Rats; Rats, Long-Evans; Receptors, Adrenergic, alpha-2; Signal Transduction; Spinal Cord; Spinal Cord Injuries

2019
Effects of propofol and dexmedetomidine anesthesia on Th1/Th2 of rat spinal cord injury.
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:6

    Topics: Anesthesia; Animals; Cytokines; Dexmedetomidine; Propofol; Rats; Spinal Cord Injuries; Th1-Th2 Balance; Time Factors

2017
Dexmedetomidine Mitigates Microglia-Mediated Neuroinflammation through Upregulation of Programmed Cell Death Protein 1 in a Rat Spinal Cord Injury Model.
    Journal of neurotrauma, 2018, 11-01, Volume: 35, Issue:21

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Anti-Inflammatory Agents; Dexmedetomidine; Inflammation; Male; Microglia; Programmed Cell Death 1 Receptor; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Up-Regulation

2018
Locomotor activity of rats with SCI is improved by dexmedetomidine by targeting the expression of inflammatory factors.
    Molecular medicine reports, 2018, Volume: 18, Issue:1

    Topics: Animals; Dexmedetomidine; Gene Expression Regulation; Inflammation Mediators; Interleukin-1beta; Locomotion; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2018
The comparison of neuroprotective effects of intrathecal dexmedetomidine and metilprednisolone in spinal cord injury.
    International journal of surgery (London, England), 2013, Volume: 11, Issue:5

    Topics: Animals; Dexmedetomidine; Disease Models, Animal; Female; Hemorrhage; Histocytochemistry; Injections, Spinal; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries; Statistics, Nonparametric

2013
Involvement of spinal microglia and interleukin-18 in the anti-nociceptive effect of dexmedetomidine in rats subjected to CCI.
    Neuroscience letters, 2014, Feb-07, Volume: 560

    Topics: Analgesics, Non-Narcotic; Animals; Cells, Cultured; Chronic Disease; Constriction, Pathologic; Dexmedetomidine; Hyperalgesia; Interleukin-18; Male; Microglia; Pain Threshold; Physical Stimulation; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Cord; Spinal Cord Injuries; Touch

2014
Dexmedetomidine for chronic spinal cord injured patient.
    Journal of anesthesia, 2014, Volume: 28, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Dexmedetomidine; Female; Humans; Male; Spinal Cord Injuries

2014
Alpha-2 agonist attenuates ischemic injury in spinal cord neurons.
    The Journal of surgical research, 2015, May-01, Volume: 195, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Cardiovascular Surgical Procedures; Cell Survival; Cells, Cultured; Cytokines; Dexmedetomidine; Drug Evaluation, Preclinical; Glucose; Hypoxia; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Spinal Cord; Spinal Cord Injuries

2015
Preclinical efficacy of Dexmedetomidine on spinal cord injury provoked oxidative renal damage.
    Renal failure, 2015, Volume: 37, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Caspase 3; Creatinine; Dexmedetomidine; Disease Models, Animal; Interleukin-6; Kidney; Oxidative Stress; Peroxidase; Postoperative Complications; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2015
The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats.
    Brain, behavior, and immunity, 2017, Volume: 64

    Topics: Adrenergic alpha-2 Receptor Agonists; alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Dexmedetomidine; Inflammation Mediators; Male; Motor Activity; Myelitis; Neurons; Rats, Sprague-Dawley; Signal Transduction; Spinal Cord Injuries; Toll-Like Receptor 4

2017
Does dexmedetomidine reduce secondary damage after spinal cord injury? An experimental study.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2009, Volume: 18, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Antioxidants; Apoptosis; Dexmedetomidine; Disease Models, Animal; Disease Progression; Energy Metabolism; Female; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Oxidative Stress; Paraplegia; Rabbits; Spinal Cord; Spinal Cord Injuries; Treatment Failure

2009
Effects of dexmedetomidine or methylprednisolone on inflammatory responses in spinal cord injury.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:8

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Dexmedetomidine; Edema; Inflammation; Interleukin-6; Male; Methylprednisolone; Neutrophil Infiltration; Rats; Rats, Wistar; Spinal Cord Injuries; Tumor Necrosis Factor-alpha

2009
The effectiveness of dexmedetomidine in experimental spinal cord injury compared to methylprednisolone in rats.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010, Volume: 17, Issue:4

    Topics: Animals; Aryldialkylphosphatase; Cholesterol, HDL; Dexmedetomidine; Lipid Peroxidation; Male; Malondialdehyde; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord Injuries

2010
Characterization of spinal alpha-adrenergic modulation of nociceptive transmission and hyperalgesia throughout postnatal development in rats.
    British journal of pharmacology, 2007, Volume: 151, Issue:8

    Topics: Adrenergic alpha-Agonists; Age Factors; Analgesics; Animals; Animals, Newborn; Dexmedetomidine; Dose-Response Relationship, Drug; Electromyography; Heart Rate; Hindlimb; Humans; Infant; Infant, Newborn; Injections, Epidural; Mustard Plant; Nerve Fibers; Pain; Pain Threshold; Plant Oils; Rats; Spinal Cord Injuries

2007