dexmedetomidine has been researched along with Postoperative Cognitive Complications in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 27 (90.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, S; He, S; Sun, Z; Wei, W; Zhang, W | 1 |
| Gao, Y; Li, F; Teng, J; Wang, W; Wang, Y; Yu, H | 1 |
| Ding, X; Guo, J; Ren, X; Su, C; Wang, H | 1 |
| Chen, J; Ding, Q; Jiao, X; Sun, Z; Wang, B; Zhang, Y; Zhao, J | 1 |
| Li, Y; Shi, Z; Wang, H; Wu, Z | 1 |
| Fan, Y; Hu, R; Liao, XZ; Liu, YF; Xiao, JF; Zhang, LF | 1 |
| Kong, G; Liu, J; Tang, Y; Wang, Y; Wei, L; Zhao, Y | 1 |
| Cao, G; Fan, J; Kang, H; Liu, B; Yu, H | 1 |
| Liu, Y; Ma, Y; Wang, P; Wang, W | 1 |
| Deng, K; Hou, M; Zhang, Q | 1 |
| Cho, I; Kam, EH; Kim, EJ; Kim, J; Kim, SY; Koo, BN; Park, S | 1 |
| Leng, Y; Wang, Y; Yu, S; Zhao, G | 1 |
| Tao, Q; Yang, N; Yu, J | 1 |
| Li, J; Zhang, H; Zhao, W | 1 |
| Hu, J; Li, Y; Long, J; Zeng, K | 1 |
| Cui, Y; Li, XF; Lv, J; Zeng, T; Zhang, Q | 1 |
| Chu, T; Liu, C; Wang, J; Xin, Y; Xu, A; Zhou, Y | 1 |
| Huang, Y; Xu, L; Xu, S; Zhang, Y | 1 |
| Chai, M; Han, M; Li, DB; Liu, YR; Wang, G; Yang, HT; Zhang, XP | 1 |
| Du, X; Ma, S; Song, F; Zhang, X | 1 |
| Chen, H; Li, F | 1 |
| Fu, Q; Liu, J; Wang, JH; Wang, PQ; Xu, ZP; Zhang, H; Zhou, XY | 1 |
| Jie, Z; Li, C; Lin, C; Tu, H; Zhou, X | 1 |
| Du, XJ; Hu, YJ; Mi, WD; Shi, HX; Wu, F | 1 |
| Deng, R; Gao, Z; Han, J; Li, Z; Liu, Q; Pu, C; Xiao, Q; Zhang, Y | 1 |
| Chen, J; Cheng, M; Li, H; Li, Z; Yao, S | 1 |
| Guo, M; Hu, C; Qin, K; Shen, Z; Wang, F; Xie, X; Zhang, K | 1 |
| Li, M; Ma, Y; Wang, Q; Yang, Y | 1 |
| Cai, DS; Wang, YL; Zhang, Y | 1 |
| Chen, N; Chen, X; Qian, J; Wu, C; Xie, J | 1 |
7 review(s) available for dexmedetomidine and Postoperative Cognitive Complications
| Article | Year |
|---|---|
Influence of dexmedetomidine on postoperative cognitive dysfunction in the elderly: A meta-analysis of randomized controlled trials.
Topics: Aged; Anesthesia, General; Cognitive Dysfunction; Dexmedetomidine; Humans; Postoperative Cognitive Complications; Postoperative Complications; Randomized Controlled Trials as Topic | 2022 |
A Review of the Biological Mechanisms of Dexmedetomidine for Postoperative Neurocognitive Disorders.
Topics: Adjuvants, Anesthesia; Aged; Delirium; Dexmedetomidine; Humans; Neurocognitive Disorders; Postoperative Cognitive Complications | 2022 |
Preventing postoperative cognitive dysfunction using anesthetic drugs in elderly patients undergoing noncardiac surgery: a systematic review and meta-analysis.
Topics: Aged; Anesthetics, Inhalation; Dexmedetomidine; Humans; Postoperative Cognitive Complications; Postoperative Complications; Sevoflurane; Sufentanil | 2023 |
Effectiveness of dexmedetomidine on postoperative cognitive dysfunction in elderly patients with fracture: A systematic review.
Topics: Aged; Cognition; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Postoperative Cognitive Complications; Postoperative Complications; Randomized Controlled Trials as Topic | 2023 |
Effects of anesthetic adjunctive agents on postoperative cognitive dysfunction in elderly patients undergoing noncardiac surgery: A Bayesian network meta-analysis.
Topics: Adjuvants, Anesthesia; Aged; Anesthetics; Bayes Theorem; Cognitive Dysfunction; Dexmedetomidine; Humans; Ketamine; Network Meta-Analysis; Postoperative Cognitive Complications; Postoperative Complications | 2023 |
Effect of Dexmedetomidine on Delirium in Elderly Surgical Patients: A Meta-analysis of Randomized Controlled Trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Bradycardia; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Length of Stay; Postoperative Cognitive Complications; Randomized Controlled Trials as Topic | 2021 |
Pharmacological Agents That Prevent Postoperative Cognitive Dysfunction in Patients With General Anesthesia: A Network Meta-analysis.
Topics: Anesthesia, General; Bayes Theorem; Cognitive Dysfunction; Dexmedetomidine; Humans; Ketamine; Network Meta-Analysis; Postoperative Cognitive Complications | 2020 |
6 trial(s) available for dexmedetomidine and Postoperative Cognitive Complications
| Article | Year |
|---|---|
Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy.
Topics: Aged; Aged, 80 and over; Bradycardia; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Hypotension; Interleukin-10; Middle Aged; Postoperative Cognitive Complications; Postoperative Complications; Prospective Studies; Tumor Necrosis Factor-alpha | 2022 |
Effects of Dexmedetomidine Anesthesia on Early Postoperative Cognitive Dysfunction in Elderly Patients.
Topics: Aged; Anesthesia; Cognitive Dysfunction; Dexmedetomidine; Humans; Inflammation; Postoperative Cognitive Complications; Postoperative Complications | 2022 |
Effect of dexmedetomidine on postoperative cognitive dysfunction in elderly patients undergoing orthopaedic surgery: study protocol for a randomized controlled trial.
Topics: Aged; Cognitive Dysfunction; Dexmedetomidine; Double-Blind Method; Humans; Orthopedic Procedures; Postoperative Cognitive Complications; Prospective Studies; Randomized Controlled Trials as Topic | 2023 |
Protective efficacy of combined use of parecoxib and dexmedetomidine on postoperative hyperalgesia and early cognitive dysfunction after laparoscopic cholecystectomy for elderly patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Analysis of Variance; Arterial Pressure; Cholecystectomy, Laparoscopic; Cyclooxygenase 2 Inhibitors; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Humans; Isoxazoles; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Postoperative Cognitive Complications; Prospective Studies; Time Factors; Treatment Outcome | 2019 |
Effect of Dexmedetomidine with Different Anesthetic Dosage on Neurocognitive Function in Elderly Patients After Operation Based on Neural Network Model.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, General; Arterial Pressure; Blood Glucose; Colorectal Neoplasms; Dexmedetomidine; Digestive System Surgical Procedures; Female; Heart Rate; Humans; Hydrocortisone; Hypnotics and Sedatives; Male; Mental Status and Dementia Tests; Middle Aged; Neural Networks, Computer; Postoperative Cognitive Complications | 2020 |
[Effects of dexmedetomidine doses on postoperative cognitive dysfunction and serum β- amyloid and cytokine levels in elderly patients after spine surgery: a randomized controlled trial].
Topics: Aged; Amyloid beta-Peptides; Anesthesia, General; Cytokines; Dexmedetomidine; Humans; Postoperative Cognitive Complications | 2021 |
17 other study(ies) available for dexmedetomidine and Postoperative Cognitive Complications
| Article | Year |
|---|---|
Protective role of dexmedetomidine against sevoflurane-induced postoperative cognitive dysfunction via the microRNA-129/TLR4 axis.
Topics: Animals; Cognitive Dysfunction; Dexmedetomidine; MicroRNAs; Postoperative Cognitive Complications; Rats; Sevoflurane; Toll-Like Receptor 4 | 2021 |
Effect of Dexmedetomidine on The Neuroglobin Expression in Elderly Patients With Minimally Invasive Coronary Artery Bypass Graft Surgery.
Topics: Aged; Analgesics, Non-Narcotic; China; Cognition; Coronary Artery Bypass; Coronary Artery Disease; Dexmedetomidine; Elective Surgical Procedures; Female; Follow-Up Studies; Humans; Incidence; Male; Minimally Invasive Surgical Procedures; Neuroglobin; Postoperative Cognitive Complications; Retrospective Studies | 2021 |
Changing Pain Management Strategy from Opioid-centric Towards Improve Postoperative Cognitive Dysfunction with Dexmedetomidine.
Topics: Adult; Analgesics, Opioid; Dexmedetomidine; Emergence Delirium; Femoral Neck Fractures; Humans; Pain; Pain Management; Postoperative Cognitive Complications | 2022 |
Dexmedetomidine attenuates hippocampal neuroinflammation in postoperative neurocognitive disorders by inhibiting microRNA-329-3p and activating the CREB1/IL1RA axis.
Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dexmedetomidine; Hippocampus; Interleukin 1 Receptor Antagonist Protein; Interleukin-6; Lipopolysaccharides; Mice; MicroRNAs; Neuroinflammatory Diseases; Postoperative Cognitive Complications; Tumor Necrosis Factor-alpha | 2022 |
Dexmedetomidine Mitigates Microglial Activation Associated with Postoperative Cognitive Dysfunction by Modulating the MicroRNA-103a-3p/VAMP1 Axis.
Topics: Aged; Animals; Dexmedetomidine; Humans; Inflammation; Lipopolysaccharides; Microglia; MicroRNAs; Postoperative Cognitive Complications; Rats; Vesicle-Associated Membrane Protein 1 | 2022 |
Effects of dexmedetomidine on cognitive dysfunction and neuroinflammation via the HDAC2/HIF-1α/PFKFB3 axis in a murine model of postoperative cognitive dysfunction.
Topics: Animals; Cognitive Dysfunction; Dexmedetomidine; Disease Models, Animal; Hippocampus; Histone Deacetylase 2; Hypoxia-Inducible Factor 1, alpha Subunit; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Phosphofructokinase-2; Postoperative Cognitive Complications | 2022 |
Study on the Effect of Dexmedetomidine on Postoperative Cognitive Dysfunction and Inflammation in Aged Rats.
Topics: Animals; Cytokines; Dexmedetomidine; Inflammation; Interleukin-6; Male; Postoperative Cognitive Complications; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2022 |
Neuroprotective Effect of Dexmedetomidine against Postoperative Cognitive Decline via NLRP3 Inflammasome Signaling Pathway.
Topics: Animals; Cognitive Dysfunction; Dexmedetomidine; Inflammasomes; Mice; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Postoperative Cognitive Complications; Signal Transduction | 2022 |
Comment on "Effects of Dexmedetomidine Anesthesia on Early Postoperative Cognitive Dysfunction in Elderly Patients".
Topics: Aged; Anesthesia; Cognitive Dysfunction; Dexmedetomidine; Humans; Postoperative Cognitive Complications | 2023 |
Dexmedetomidine mitigates neuroinflammation and improves early postoperative neurocognitive dysfunction in rats by enhancing autophagy.
Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Beclin-1; Cognitive Dysfunction; Cytokines; Dexmedetomidine; Hippocampus; Neuroinflammatory Diseases; Postoperative Cognitive Complications; Rats; Rats, Sprague-Dawley | 2023 |
High‑fat treatment prevents postoperative cognitive dysfunction in a hyperlipidemia model by protecting the blood‑brain barrier via Mfsd2a‑related signaling.
Topics: Animals; Blood-Brain Barrier; Dexmedetomidine; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Hyperlipidemias; Membrane Transport Proteins; Permeability; Postoperative Cognitive Complications; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction | 2019 |
Dexmedetomidine ameliorates postoperative cognitive dysfunction by inhibiting Toll-like receptor 4 signaling in aged mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Animals; Cell Line; Dexmedetomidine; Gene Expression Regulation; Hepatectomy; Hippocampus; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Postoperative Cognitive Complications; Signal Transduction; Spatial Memory; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
Dexmedetomidine for early postoperative cognitive dysfunction after video-assisted thoracoscopic lobectomy in elderly male patients with lung cancer.
Topics: Aged; Analgesics, Non-Narcotic; Controlled Before-After Studies; Dexmedetomidine; Humans; Lung Neoplasms; Male; Mental Status and Dementia Tests; Middle Aged; Postoperative Cognitive Complications; Retrospective Studies; Thoracic Surgery, Video-Assisted | 2020 |
Dexmedetomidine improves postoperative neurocognitive disorder after cardiopulmonary bypass in rats.
Topics: Amyloid beta-Peptides; Animals; Brain; Cardiopulmonary Bypass; Dexmedetomidine; Inflammation Mediators; Male; Maze Learning; Postoperative Cognitive Complications; Rats, Sprague-Dawley; tau Proteins | 2021 |
Dexmedetomidine Ameliorates Postoperative Cognitive Dysfunction in Aged Mice.
Topics: Abdomen; Animals; Anti-Inflammatory Agents; Antioxidants; Brain-Derived Neurotrophic Factor; Cyclin-Dependent Kinase 5; Cytokines; Dexmedetomidine; Hippocampus; Male; Malondialdehyde; Mice, Inbred C57BL; Microglia; Morris Water Maze Test; Neuroprotective Agents; Open Field Test; Postoperative Cognitive Complications; Superoxide Dismutase | 2021 |
Dexmedetomidine Ameliorates Postoperative Cognitive Dysfunction via the MicroRNA-381-Mediated EGR1/p53 Axis.
Topics: Animals; Dexmedetomidine; Early Growth Response Protein 1; Hippocampus; Male; Mice; Mice, Inbred C57BL; MicroRNAs; Postoperative Cognitive Complications; Tumor Suppressor Protein p53 | 2021 |
Dexmedetomidine protects aged rats from postoperative cognitive dysfunction by alleviating hippocampal inflammation.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Animals; Dexmedetomidine; Hippocampus; Hypnotics and Sedatives; Inflammation; Interleukin-1beta; Male; Postoperative Cognitive Complications; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2019 |