dexmedetomidine has been researched along with Pain in 141 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 26 (18.44) | 29.6817 |
| 2010's | 63 (44.68) | 24.3611 |
| 2020's | 52 (36.88) | 2.80 |
| Authors | Studies |
|---|---|
| Aghaali, M; Ahmadpour, S; Alemi, F; Aminnejad, R; Hormati, A; Hormati, M; Sabouri, SM; Saeidi, M; Shafiee, H | 1 |
| Ding, X; Guo, J; Ren, X; Su, C; Wang, H | 1 |
| Bharati, SJ; Bhatnagar, S; Garg, R; Gupta, N; Hadda, V; Kumar, V; Madan, K; Mishra, S; Mittal, S; Mohan, A; Sagiraju, HKR; Sirohiya, P | 1 |
| Campher, MJJ; Eley, VA; Laupland, KB; Sin, JCK; Tabah, A | 1 |
| Moshari, A; Moshari, M; Vahedi, Z | 1 |
| Feng, YJ; Han, J; Pu, CX; Tang, LJ; Zhang, Y | 1 |
| Hui, D; Jianwei, G; Jing, Z; Lijuan, Z; Ronglin, L; Yanan, J | 1 |
| Chen, XL; Huang, WH; Zhang, GC; Zheng, YH | 1 |
| Cao, R; Fan, M; Hu, L; Li, J; Lu, S | 1 |
| Cren, R; De Kock, M; Grégoire, C; Henrie, J; Lavand'homme, P; Penaloza, A; Verschuren, F | 1 |
| He, Y; Hu, R; Ning, R; Niu, J; Sun, H; Yang, N; Yu, J | 1 |
| Huang, Z; Lai, L; Shan, R; Sun, C; Xiao, C; Zhan, L; Zhang, X; Zhao, W | 1 |
| Chai, X; Chu, L; Liao, B; Wang, XF; Wei, JM; Yang, JS; Zhang, R; Zhang, X; Zhao, YT; Zou, P | 1 |
| Al Assadi, S; Kanazi, G; Karam, C; Zeeni, C | 1 |
| Lu, YJ; Shao, JL; Shen, R; Wang, L; Yang, ZH; Zhan, FF | 1 |
| Jiang, L; Lu, B; Pang, G; Rao, C; Tong, S; Zhu, Y | 1 |
| Azemati, S; Jouybar, R; Naderi-Boldaji, V; Zarghami, A | 1 |
| Anghelescu, DL; Baker, JN; Bhatia, S; Cuviello, A; Johnson, LM; Pasli, M | 1 |
| Hao, D; Zhang, Z | 1 |
| Abramson, J; Dorling, J; Ojha, S | 1 |
| Avet, C; Basbaum, AI; Bouvier, M; Braz, JM; Chen, G; Craik, V; Du, Y; Fink, EA; Gahbauer, S; Gmeiner, P; Huang, XP; Hübner, H; Irwin, JJ; Jacobson, MP; Kalyanaraman, C; Liu, Z; Moroz, YS; Schmidt, MF; Seemann, P; Shoichet, BK; Tolmachova, NA; Webb, CM; Weikert, D; Xu, J | 1 |
| Chen, Y; Cheng, O; Cui, J; Li, C; Li, Y; Zhu, D | 1 |
| Bartoletta, KM; Collura, CA; Thorvilson, MJ | 1 |
| Bäcke, P; Bruschettini, M; Olsson, E; Sibrecht, G; Thernström Blomqvist, Y | 1 |
| Miskimins, R; Mitchell, J; Sarangarm, P; Wiemann, B | 1 |
| Garip, L; Mesotten, D; Meyns, J; Stragier, H; Verbist, J; Vundelinckx, J | 1 |
| Ahuja, V; Aravindan, A; Datta, PK; Ganesh, V; Iyer, KV; Khanna, P; Maitra, S; Sarkar, S; Singh, A | 1 |
| Dersch-Mills, D; Howlett, A; Lind, J; Marchuk, A; Mohammad, K | 1 |
| Huang, Y; Wang, C; Wang, T; Wang, X; Wu, H; Zhang, S; Zhao, G | 1 |
| Al-Bermani, T; Al-Mufti, F; Ali, S; Bass, B; Bauerschmidt, A; Dorilio, J; Rosenberg, J | 1 |
| Geng, D; Gu, C; Hao, Y; Li, X; Qian, X; Shi, Y; Tao, H; Yang, X; Zhang, C; Zhang, L; Zhou, J | 1 |
| He, Y; Hou, YB; Ning, RD; Niu, JY; Tao, QY; Yang, N; Yu, JM | 1 |
| Dieudonné Rahm, N; Elia, N; Gil Wey, B; Habre, W; Pautex, S; Zaccaria, I | 1 |
| Raman, R; Raman, S; Surya, J; Viswanathan, J | 1 |
| Chen, C; Chen, W; Gao, P; Li, YH; Lu, Y; Rao, J | 1 |
| Li, Z; Lu, Y; Ma, X; Sun, H; Wang, S; Zhu, H | 1 |
| Harada, H; Ikeda, K; Kamei, J; Kato, T; Kitajima, N; Kuriyama, A; Maeda, J; Matsuyama, A; Minami, T; Mizota, T; Ohtsuru, S; Sakai, Y; Sato, Y; Takatani, Y; Ueno, K; Watanabe, H; Yamaji, K; Yamashita, Y | 1 |
| Hao, C; Li, H; Luan, H; Zhang, X; Zhao, Z; Zhu, P | 1 |
| Konishi, S; Miyashima, Y; Nakamura, H; Uemura, T | 1 |
| Dinges, HC; Eberhart, L; Schubert, AK; Seneviratne, V; Stolz, J; Wiesmann, T; Wulf, H | 1 |
| Bromfalk, Å; Engström, Å; Hultin, M; Myrberg, T; Walldén, J | 1 |
| Du, B; Guo, Q; Qi, X; Wang, B; Xiao, F; Zhang, H; Zhang, J | 1 |
| Ali, KA; Deng, X; Fang, Z; Li, W; Li, Y | 1 |
| Cheng, Y; Li, S; Lin, Z; Lu, X; Sun, J; Yang, B; Yu, Z; Zhou, Y | 1 |
| Anderson, J; Mandell, SP; McClellan, JM; O'Neal, J; Sheckter, C; Stanton, E | 1 |
| Kim, MD | 1 |
| Donato, J; Lewis, T; Rao, K | 1 |
| Carregaro, AB; de Carvalho, LL; Flaherty, D; Mattos-Junior, E; Nishimura, LT | 1 |
| El-Dib, M; Inder, TE; Massaro, AN; McPherson, C; Miller, SP | 1 |
| Ji, L; Lan, Y; Sun, W; Wu, Q; Xia, C; Xu, X; Yang, S; Yu, G | 1 |
| Date, K; Iino, K; Kawata, M; Kyo, S; Mano, A; Murata, T; Saito, E; Sato, M; Yamashita, N | 1 |
| Cox, CE; Gilstrap, DL; Kram, BL; Kram, SJ; Ohman, KL; Schultheis, JM; Yang, Z | 1 |
| Järvisalo, MJ; Seppänen, SM; Uusalo, P | 1 |
| Atyia, SA; Cape, KM; May, CC; Smetana, KS; Thompson, MJ; Tong, MC | 1 |
| Leng, YF; Liu, YQ; Wan, ZH; Wang, DG; Yan, X; Zhang, H; Zhang, Y | 1 |
| Davoudi, A; Movahedian Attar, B; Shadmehr, E | 1 |
| Hu, B; Li, JG; Peng, ZY; Rao, X; Wang, J; Zhou, WH | 1 |
| Aoun, Z; Bazarbachi, T; Dabar, G; Habr, B; Ibrahim, I; Khalil, N; Khayat, G; Riachy, M | 1 |
| Amaya, F; Matsuda, M; Sawa, T; Yamaguchi, Y; Yamakita, S | 1 |
| Chen, CJ; Hei, ZQ; Li, X; Pan, JR; Tan, F; Xing, JB; Zhou, SL; Zhu, QQ | 1 |
| Han, LL; Li, QD; Li, SW; Li, WW; Shi, HY; Wan, XY; Zhang, YL | 1 |
| Bruña, V; Devesa, C; Fernández-Avilés, F; Gonzalez-Saldivar, H; Iglesias, M; Juárez, M; Martínez-Sellés, M; Sousa-Casasnovas, I; Valero-Masa, MJ; Vicent, L | 1 |
| Chlan, L; Hayes, SM; Hetland, B; Skaar, D; Tracy, MF; Weinert, CR | 1 |
| Berggren, L; Blomqvist, H; Forsberg, S; Nunes, SL; Sarapohja, T; Sörberg, M; Wickerts, CJ | 1 |
| Chen, WR; Ji, FH; Meng, XW; Peng, K; Zhang, J | 1 |
| Hu, B; Zhou, H; Zou, X | 1 |
| Hua, H; Jiang, M; Liu, Z; Xu, T | 1 |
| Matsumoto, Y; Murakami, Y; Nakata, M; Torumi, T; Yoshimura, M | 1 |
| Xie, M; Xie, S | 1 |
| Kiski, D; Malec, E; Schmidt, C | 1 |
| Yu, Y; Zhang, T; Zhang, W; Zhu, J | 1 |
| Coursey, CD; Lizarraga, I; Scallan, EM; Simon, BT; Wild, JL | 1 |
| Chambers, P; Karna, SR; Kongara, K; Lopez-Villalobos, N; Singh, PM | 1 |
| Abrams, D; Agerstrand, C; Brodie, D; Dzierba, AL; Madahar, P; Muir, J | 1 |
| Cao, J; Kong, M; Li, C; Liu, H; Ma, H; Zhang, H; Zhang, L; Zhang, P; Zhang, S; Zhou, F | 1 |
| Asmussen, S; Fraser, JF; George, S; Jennings, K; Maybauer, DM; Maybauer, MO | 1 |
| Bergfeld, C; Beyerbach, M; Kästner, SB; Voigt, AM | 1 |
| Chang, CH; Han, DW; Kim, MD; Kim, SY; Kim, YJ; Lee, JS | 1 |
| Bosmans, T; de Rooster, H; Debille, M; Duchateau, L; Polis, I; Porters, N | 1 |
| Jang, Y; Kang, ES; Kang, JW; Song, HK; Yeom, MY | 1 |
| Dong, C; Lu, Y; Yu, J; Zhang, Y | 1 |
| Malotte, K; Rosielle, DA; Walker, K | 1 |
| Chen, XD; Meng, QT; Pan, X; Xia, ZY; Yang, YC | 1 |
| Bosmans, T; de Rooster, H; Duchateau, L; Goethals, K; Moons, CP; Polis, I; Porters, N | 1 |
| Baek, J; Joo, J; Lee, J | 1 |
| Cheung, W; Deyell, R; Görges, M; Lauder, G; West, N; Winton, P | 1 |
| He, L; He, T; Liu, L; Xu, JM; Zhu, R | 1 |
| Huang, F; Jin, J; Kong, J; Liu, S; Wang, J; Xu, H; Yang, X | 1 |
| Afsar, N; Almeida, LE; Calhoun, G; Finkel, JC; Kenyon, N; Nouraie, M; Quezado, ZM; Wang, L | 1 |
| Cheung, CW; Li, S; Qian, L; Wu, Y; Yang, Y; Yao, Y; Yu, C | 1 |
| Darbari, DS; Finkel, JC; Guerrera, MF; Quezado, ZM; Sheehy, KA | 1 |
| Dong, C; Feng, F; Li, J; Qi, Y; Song, R; Yang, J; Yang, Z; Zhang, H | 1 |
| Dong, C; Li, J; Song, R; Yang, J | 1 |
| An, Y; Feng, Y; Liu, D; Lyu, J | 1 |
| Cao, WZ; Xu, SA; Xu, XQ; Yu, HJ | 1 |
| Chen, D; Huang, X; Li, G; Li, Y; Qi, X; Wang, X | 1 |
| Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S | 1 |
| Burns, J; Finkel, JC; Jackson, K; Quezado, ZM; Sheehy, KA | 1 |
| Fujino, Y; Hirao, O; Mashimo, T; Ohashi, Y; Ohta, N; Uchiyama, A | 1 |
| Christianson, CA; Hua, XY; Nazarian, A; Yaksh, TL | 1 |
| Dupont, WD; Friedman, EA; Harris, PA; Kohli, U; Kurnik, D; Muszkat, M; Scheinin, M; Sofowora, GG; Stein, CM; Wood, AJ | 1 |
| Bilge, SS; Bostanci, MO; Bozkurt, A; Ciftcioglu, E; Dilek, A; Güldogus, F; Ilkaya, F; Ulger, F | 1 |
| Kohase, H; Makino, K; Sanada, T; Umino, M | 1 |
| Bilgin, F; Cosar, A; Isik, S; Ozturk, S; Zor, F | 1 |
| Kimura, T; Masaki, Y; Nishikawa, T; Sato, K; Tobe, Y | 1 |
| Budak, ET; Dagli, G; Dere, K; Filiz, AI; Ozkan, S; Sucullu, I; Yeyen, S | 1 |
| Boehm, CA; Carney, EL; Tallarida, RJ; Wilson, RP | 1 |
| Anger, KE; Baroletti, SA; Fanikos, J; Labreche, MJ; Szumita, PM | 1 |
| Allegaert, K; Thewissen, L | 1 |
| Kanai, T; Maruta, T; Nemoto, T; Satoh, S; Tsuneyoshi, I; Wada, A; Yanagita, T | 1 |
| Davis, J; Reimer, EJ; Whyte, E; Whyte, S; Winton, P | 1 |
| Sezer, G; Sezer, Z; Tekol, Y | 1 |
| Fukusaki, M; Higashijima, U; Ichinomiya, T; Miura, K; Sumikawa, K; Tanise, T; Terao, Y | 1 |
| Arendt-Nielsen, L; Baba, Y; Fujii-Abe, K; Kohase, H; Oono, Y | 1 |
| Bruce, W; Compton, J; Fonder, H; Garrett, N | 1 |
| Bratty, JR; Garratt, C; Grounds, RM; Jakob, SM; Pocock, SJ; Ruokonen, E; Sarapohja, T; Takala, J | 1 |
| Aydogan, MS; Durmus, M; Erdogan, MA; Kurt, A; Parlakpinar, H; Ucar, M; Yucel, A | 1 |
| de Moura, RS; Fernandes, PD; Lessa, MA; Marinho, BG; Rangel, RA | 1 |
| Anger, KE | 1 |
| Halttunen, J; Kylänpää, L; Lindström, O; Mazanikov, M; Mustonen, H; Pöyhiä, R; Udd, M | 1 |
| Serlin, S | 1 |
| Taiji, K | 1 |
| Angus, JA; Tham, SM; Tudor, EM; Wright, CE | 1 |
| Karamanlioglu, B; Kaya, G; Memis, D; Seker, S; Turan, A | 1 |
| Karamanlioglu, B; Kaya, G; Memis, D; Turan, A | 1 |
| Ishio, E; Iwasaki, H; Kunisawa, T; Nagata, O; Ogasawara, H; Takahata, O | 1 |
| Bagcivan, I; Cetin, A; Gulturk, S; Gursoy, S; Karadas, B; Kaya, T; Parlak, A | 1 |
| Boyaci, A; Gulcu, N; Ugur, F | 1 |
| Altunkaya, H; Ayoğlu, H; Cukdar, G; Ozer, Y; Ozkoçak, I; Yapakçi, O | 1 |
| Fitzgerald, M; Walker, SM | 1 |
| Leitch, J; Macpherson, A | 1 |
| Yaksh, TL | 1 |
| Apaydin, S; Guneli, E; Karabay Yavasoglu, NU; Uyar, M | 1 |
| Dickey, S; Gadiraju, S; Galli, R; Lerant, AA; Phillips, WJ | 1 |
| Adanir, T; Konakci, S; Rezanko, T; Yilmaz, G | 1 |
| Slingsby, LS; Taylor, PM | 1 |
| Pertovaara, A; Wei, H | 1 |
| Kalso, E; Kontinen, VK; Xu, M | 1 |
| Basbaum, AI; Hedley, LR; Hunter, JC; Jasper, JR; Malmberg, AB | 1 |
| Ben-Abraham, R; Weinbroum, AA | 1 |
17 review(s) available for dexmedetomidine and Pain
| Article | Year |
|---|---|
The Effect of Dexmedetomidine on Postanesthesia Care Unit Discharge and Recovery: A Systematic Review and Meta-Analysis.
Topics: Adult; Anesthesia, General; Bradycardia; Cough; Dexmedetomidine; Emergence Delirium; Humans; Hypotension; Pain; Patient Discharge; Postoperative Nausea and Vomiting | 2022 |
Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Dexmedetomidine; Humans; Infant, Newborn; Infant, Premature; Pain; Pain Management; Respiration, Artificial; Respiratory Insufficiency | 2022 |
Pharmacological interventions for pain and sedation management in newborn infants undergoing therapeutic hypothermia.
Topics: Clonidine; Dexmedetomidine; Humans; Hypothermia, Induced; Infant, Newborn; Morphine Derivatives; Observational Studies as Topic; Pain | 2022 |
Modern Sedation and Analgesia Strategies in Neurocritical Care.
Topics: Analgesia; Critical Care; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Propofol; Respiration, Artificial | 2023 |
The effect of adjuvants added to local anaesthetics for single-injection upper extremity peripheral regional anaesthesia: A systematic review with network meta-analysis of randomised trials.
Topics: Anesthesia, Conduction; Anesthetics, Local; Dexamethasone; Dexmedetomidine; Humans; Ketorolac; Midazolam; Network Meta-Analysis; Pain; Randomized Controlled Trials as Topic; Upper Extremity | 2023 |
Pharmacology of Common Analgesic and Sedative Drugs Used in the Neonatal Intensive Care Unit.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modality Therapy; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Midazolam; Morphine; Pain; Pain Management; Pharmacogenomic Variants; Precision Medicine; Remifentanil | 2019 |
The influence of pain, agitation, and their management on the immature brain.
Topics: Algorithms; Analgesics, Opioid; Brain; Chronic Pain; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Morphine; Neuroimaging; Pain; Pain Management; Remifentanil; Respiration, Artificial; Stress, Psychological; Sucrose | 2020 |
Dexmedetomidine for prevention of propofol injection pain upon induction of anesthesia: a meta-analysis.
Topics: Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Intravenous; Dexmedetomidine; Humans; Pain; Propofol; Randomized Controlled Trials as Topic | 2020 |
Risks and benefits of pre-operative dexmedetomidine in oral and maxillofacial surgeries: a systematic review.
Topics: Anxiety; Dexmedetomidine; Humans; Hypnotics and Sedatives; Oral Surgical Procedures; Pain; Preoperative Care; Randomized Controlled Trials as Topic | 2017 |
Intra-articular dexmedetomidine in knee arthroscopy: A systematic review and meta-analysis.
Topics: Adult; Analgesia; Analgesics, Non-Narcotic; Arthroscopy; Dexmedetomidine; Female; Humans; Knee; Male; Pain; Randomized Controlled Trials as Topic; Treatment Outcome | 2018 |
Use of dexmedetomidine in pediatric cardiac anesthesia.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Cardiac Procedures; Cardiac Surgical Procedures; Child; Dexmedetomidine; Heart; Humans; Kidney; Nervous System; Pain; Randomized Controlled Trials as Topic; Treatment Outcome | 2019 |
A meta-analysis of analgesic and sedative effects of dexmedetomidine in burn patients.
Topics: Analgesics, Non-Narcotic; Burns; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Pain | 2013 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; Clonidine; Critical Care; Cyclohexanecarboxylic Acids; Dexmedetomidine; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydromorphone; Intensive Care Units; Ketamine; Lidocaine; Morphine; Pain; Pain Management; Pain Measurement; Pain, Postoperative; Physical Therapy Modalities | 2017 |
Analgosedation in neonates: do we still need additional tools after 30 years of clinical research?
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics, Opioid; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant, Newborn; Midazolam; Morphine; Pain; Pain Measurement; Piperidines; Propofol; Quality of Health Care; Remifentanil | 2011 |
Dexmedetomidine: a review of its use for the management of pain, agitation, and delirium in the intensive care unit.
Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Pain Management; Psychomotor Agitation | 2013 |
[Dexmedetomidine hydrochloride (Precedex), a new sedative in intensive care, its pharmacological characteristics and clinical study result].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Critical Care; Dexmedetomidine; Dose-Response Relationship, Drug; Escape Reaction; Humans; Hypnotics and Sedatives; Locus Coeruleus; Mice; Motor Activity; Multicenter Studies as Topic; Pain; Rats | 2004 |
Dextromethorphan and dexmedetomidine: new agents for the control of perioperative pain.
Topics: Adrenergic alpha-Agonists; Analgesics; Animals; Dexmedetomidine; Dextromethorphan; Humans; N-Methylaspartate; Pain; Pain, Postoperative; Premedication; Receptors, Adrenergic, alpha-2; Receptors, N-Methyl-D-Aspartate | 2001 |
53 trial(s) available for dexmedetomidine and Pain
| Article | Year |
|---|---|
Comparing the Efficacy and Safety of Dexmedetomidine/Ketamine with Propofol/Fentanyl for Sedation in Colonoscopy Patients: A Doubleblinded Randomized Clinical Trial.
Topics: Apnea; Colonoscopy; Dexmedetomidine; Double-Blind Method; Fentanyl; Humans; Hypnotics and Sedatives; Hypotension; Ketamine; Pain; Propofol; Prospective Studies | 2022 |
Dexmedetomidine Versus Midazolam for Sedation During Medical Thoracoscopy: A Pilot Randomized-Controlled Trial (RCT).
Topics: Analgesics, Opioid; Conscious Sedation; Cough; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Midazolam; Pain; Pilot Projects; Thoracoscopy | 2022 |
Efficacy of adding dexmedetomidine to lidocaine to enhance inferior alveolar nerve block in patients with asymptomatic irreversible pulpitis: double-blind randomized clinical trial.
Topics: Adult; Anesthesia, Dental; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Humans; Lidocaine; Mandibular Nerve; Nerve Block; Pain; Pulpitis | 2022 |
Comparative study of the efficacy of dexmedetomidine and fentanyl on anxiety and pain of parturients with different COMTva1158met genotypes.
Topics: Analgesia, Epidural; Analgesics, Opioid; Anxiety; Dexmedetomidine; Female; Fentanyl; Genotype; Humans; Pain; Pregnancy | 2022 |
A Comparative Study on Sedation Efficacy Between General and Regional Anesthesia with Dexmedetomidine in Patients Under Maxillofacial Surgery.
Topics: Adult; Anesthesia, Conduction; Anesthesia, General; Dexmedetomidine; Humans; Middle Aged; Pain; Surgery, Oral; Young Adult | 2022 |
Comparison of the efficacy and safety of sedation protocols with the use of dexmedetomidine-remifentanil and propofol-remifentanil during percutaneous closure of atrial septal defects: a randomized clinical trial.
Topics: Clinical Protocols; Dexmedetomidine; Drug Combinations; Heart Septal Defects, Atrial; Humans; Hypercapnia; Hypnotics and Sedatives; Pain; Propofol; Remifentanil; Treatment Outcome | 2022 |
Efficacy and safety of dexmedetomidine-ropivacaine versus sufentanil-ropivacaine for epidural labor analgesia: a randomized controlled trial.
Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Anesthetics, Local; Dexmedetomidine; Female; Humans; Infant, Newborn; Pain; Ropivacaine; Sufentanil | 2022 |
Effect of intratracheal dexmedetomidine combined with ropivacaine on postoperative sore throat: a prospective randomised double-blinded controlled trial.
Topics: Dexmedetomidine; Humans; Intubation, Intratracheal; Pain; Pharyngitis; Postoperative Complications; Prospective Studies; Ropivacaine | 2022 |
Effect of dexmedetomidine administration on analgesic, respiration and inflammatory responses in patients undergoing percutaneous endoscopic lumbar discectomy: a prospective observational study.
Topics: Adult; Analgesics; Dexmedetomidine; Diskectomy; Diskectomy, Percutaneous; Endoscopy; Humans; Inflammation; Interleukin-6; Intervertebral Disc Displacement; Lumbar Vertebrae; Pain; Respiration; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha | 2022 |
Analgesic Characteristics of Bupivacaine Alone and in Combination with Dexmedetomidine or Meperidine in Spinal Anesthesia during Cesarean Section: A Double-Blind Randomized Clinical Trial Study.
Topics: Analgesics; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dexmedetomidine; Double-Blind Method; Female; Humans; Injections, Spinal; Meperidine; Pain; Pregnancy | 2022 |
Optimal Dose of Dexmedetomidine for Preemptive Analgesia Combined with Transversus Abdominis Plane Block after Colon Cancer Surgery.
Topics: Abdominal Muscles; Analgesia; Anesthetics, Local; Colonic Neoplasms; Dexmedetomidine; Double-Blind Method; Humans; Pain; Pain, Postoperative; Prospective Studies; Ropivacaine | 2022 |
Ketamine and dexmedetomidine (Keto-dex) or ketamine and propofol (Keto-fol) for procedural sedation during endoscopic retrograde cholangiopancreatography: Which is safer? A randomized clinical trial.
Topics: Adolescent; Adult; Aged; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Ketamine; Middle Aged; Pain; Propofol; Prospective Studies; Young Adult | 2022 |
Real-time evaluation of the independent analgesic efficacy of dexmedetomidine.
Topics: Analgesia; Analgesics; Dexmedetomidine; Humans; Midazolam; Pain | 2023 |
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Elective Spinal Surgery: A Prospective Randomized Double-Blinded Controlled Trial.
Topics: Aged; Anesthesia, General; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Pain; Prospective Studies | 2023 |
Intranasal Dexmedetomidine for Pain Management in Older Patients: A Cross-Over, Randomized, Double-Blinded, Active-Controlled Trial.
Topics: Administration, Intranasal; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Pain; Pain Management | 2023 |
Single-bolus dexmedetomidine in prevention of emergence delirium in pediatric ophthalmic surgeries: A randomized controlled trial.
Topics: Blood Pressure; Child; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Pain; Postoperative Complications | 2023 |
Effect of different modes of administration of dexmedetomidine on the quality of recovery in ambulatory thyroidectomy: a randomized, controlled trial.
Topics: Adjuvants, Immunologic; Dexmedetomidine; Humans; Pain; Ropivacaine; Thyroidectomy | 2023 |
Low-dose intranasal dexmedetomidine premedication improves epidural labor analgesia onset and reduces procedural pain on epidural puncture: a prospective randomized double-blind clinical study.
Topics: Analgesia, Epidural; Analgesia, Obstetrical; Analgesics; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Infant, Newborn; Pain; Pain Management; Pain, Procedural; Prospective Studies; Punctures; Ropivacaine; Sufentanil | 2023 |
Dexmedetomidine versus haloperidol for sedation of non-intubated patients with hyperactive delirium during the night in a high dependency unit: study protocol for an open-label, parallel-group, randomized controlled trial (DEX-HD trial).
Topics: Critical Illness; Delirium; Dexmedetomidine; Drugs, Investigational; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Psychomotor Agitation; Randomized Controlled Trials as Topic | 2023 |
Effect of interscalene brachial plexus block with dexmedetomidine and ropivacaine on postoperative analgesia in patients undergoing arthroscopic shoulder surgery: a randomized controlled clinical trial.
Topics: Adult; Analgesia; Brachial Plexus Block; Dexmedetomidine; Humans; Pain; Ropivacaine; Shoulder; Sufentanil | 2023 |
Postoperative recovery in preschool-aged children: A secondary analysis of a randomized controlled trial comparing premedication with midazolam, clonidine, and dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, General; Child; Child, Preschool; Clonidine; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Hypnotics and Sedatives; Midazolam; Pain; Premedication | 2023 |
Dexamethasone and dexmedetomidine as adjuvants to ropivacaine do not prolong analgesia in wound infiltration for lumbar spinal fusion: a prospective randomized controlled study.
Topics: Adult; Agnosia; Analgesia; Analgesics, Opioid; Dexamethasone; Dexmedetomidine; Humans; Hydromorphone; Lumbar Vertebrae; Pain; Prospective Studies; Ropivacaine; Spinal Fusion | 2023 |
A comparative study of esketamine-dexmedetomidine and sufentanil-dexmedetomidine for sedation and analgesia in lung tumor percutaneous radiofrequency ablation (PRFA): a randomized double-blind clinical trial.
Topics: Aged; Analgesia; Anesthesia; Dexmedetomidine; Humans; Lung Neoplasms; Pain; Sufentanil | 2023 |
Clinical effects of epidurally administered dexmedetomidine with or without lidocaine in sheep.
Topics: Anesthetics, Local; Animals; Blood Pressure; Dexmedetomidine; Drug Combinations; Female; Heart Rate; Hypnotics and Sedatives; Injections, Epidural; Lidocaine; Male; Pain; Respiratory Rate; Sheep | 2020 |
A randomized double-blind controlled trial comparing three sedation regimens during flexible bronchoscopy: Dexmedetomidine, alfentanil and lidocaine.
Topics: Adolescent; Adult; Aged; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bronchoscopy; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Pain; Pain Measurement; Retrospective Studies; Young Adult | 2018 |
Effect of dexmedetomidine for attenuation of propofol injection pain in electroconvulsive therapy: a randomized controlled study.
Topics: Adolescent; Adult; Analgesics; Dexmedetomidine; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Male; Pain; Pain Measurement; Propofol; Young Adult | 2018 |
Letting the Patient Decide: A Case Report of Self-Administered Sedation During Mechanical Ventilation.
Topics: Dexmedetomidine; Education, Nursing, Continuing; Female; Humans; Hypnotics and Sedatives; Middle Aged; Pain; Patient Participation; Patient Satisfaction; Pilots; Respiration, Artificial; Self Administration; Treatment Outcome | 2018 |
Analgesic effect of Ropivacaine combined with Dexmedetomidine on brachial plexus block.
Topics: Adult; Analgesics, Non-Narcotic; Brachial Plexus Block; Dexmedetomidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Oxygen; Pain; Ropivacaine; Time Factors; Visual Analog Scale; Young Adult | 2018 |
[Comparison between Dexmedetomidine and Fentanyl Infusion during Fetoscopic Laser Photocoagulation for Twin to Twin Transfusion Syndrome].
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Dexmedetomidine; Female; Fentanyl; Fetofetal Transfusion; Humans; Lidocaine; Light Coagulation; Pain; Pain Management; Pregnancy; Prospective Studies | 2017 |
Comparison of dexmedetomidine and sufentanil as adjuvants to local anesthetic for epidural labor analgesia: a randomized controlled trial.
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Local; Anesthetics, Local; Dexmedetomidine; Double-Blind Method; Female; Humans; Labor, Obstetric; Pain; Pain Measurement; Pregnancy; Prospective Studies; Sufentanil; Young Adult | 2019 |
Thermal antinociceptive, sedative and cardiovascular effects of Governing Vessel 1 dexmedetomidine pharmacopuncture in healthy cats.
Topics: Acupuncture Analgesia; Animals; Cats; Conscious Sedation; Cross-Over Studies; Dexmedetomidine; Female; Heart Rate; Hot Temperature; Muscle Relaxation; Pain; Random Allocation; Respiration; Skin Temperature | 2019 |
Effects of isoflurane with and without dexmedetomidine or remifentanil on heart rate variability before and after nociceptive stimulation at different multiples of minimum alveolar concentration in dogs.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Cross-Over Studies; Dexmedetomidine; Dogs; Drug Therapy, Combination; Female; Heart Rate; Isoflurane; Male; Pain; Piperidines; Pulmonary Alveoli; Remifentanil | 2013 |
Comparison of the efficacy of dexmedetomidine plus fentanyl patient-controlled analgesia with fentanyl patient-controlled analgesia for pain control in uterine artery embolization for symptomatic fibroid tumors or adenomyosis: a prospective, randomized st
Topics: Adenomyosis; Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Chemoembolization, Therapeutic; Dexmedetomidine; Drug Therapy, Combination; Female; Fentanyl; Humans; Leiomyoma; Pain; Pain Measurement; Premedication; Prospective Studies; Self Administration; Treatment Outcome; Uterine Artery Embolization; Uterine Neoplasms | 2013 |
Sedative and antinociceptive effects of dexmedetomidine and buprenorphine after oral transmucosal or intramuscular administration in cats.
Topics: Administration, Mucosal; Analgesics; Animals; Buprenorphine; Cat Diseases; Cats; Dexmedetomidine; Drug Therapy, Combination; Female; Hypnotics and Sedatives; Injections, Intramuscular; Pain | 2014 |
Preemptive dexmedetomidine to prevent propofol injection pain in children.
Topics: Anesthetics, Intravenous; Anesthetics, Local; Child; Child, Preschool; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Lidocaine; Male; Midazolam; Pain; Pain Measurement; Propofol | 2015 |
Dexmedetomidine reduces pain associated with rocuronium injection without causing a decrease in BIS values: a dose-response study.
Topics: Adult; Analgesics, Non-Narcotic; Androstanols; Anesthesia, General; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Humans; Injections, Intravenous; Male; Middle Aged; Monitoring, Intraoperative; Neuromuscular Nondepolarizing Agents; Pain; Pain Measurement; Premedication; Propofol; Rocuronium; Young Adult | 2014 |
Dexmedetomidine pretreatment alleviates propofol injection pain.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dexmedetomidine; Double-Blind Method; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pain; Pain Management; Pain Measurement; Propofol; Prospective Studies; Triglycerides; Young Adult | 2014 |
[Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation].
Topics: Aged; Analgesics; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Postoperative Care; Postoperative Period; Propofol; Respiration, Artificial; Time Factors | 2014 |
Dexmedetomidine Analgesia Effects in Patients Undergoing Dental Implant Surgery and Its Impact on Postoperative Inflammatory and Oxidative Stress.
Topics: Adult; Analgesics, Non-Narcotic; Dental Implants; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypnotics and Sedatives; Inflammation; Interleukin-6; Male; Malondialdehyde; Midazolam; Middle Aged; Oxidative Stress; Pain; Postoperative Complications; Severity of Illness Index; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2015 |
[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit].
Topics: Analgesics; Circadian Rhythm; Critical Care; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Propofol; Prospective Studies; Respiration, Artificial | 2016 |
[A study of using dexmedetomidine in ventilator bundle treatment in an ICU].
Topics: Arterial Pressure; Blood Pressure; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Midazolam; Pain; Prospective Studies; Respiration, Artificial; Single-Blind Method | 2015 |
[The influence of the sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients].
Topics: Analgesia; Arterial Pressure; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Midazolam; Pain; Piperidines; Prospective Studies; Remifentanil; Respiration, Artificial | 2015 |
[Analgesic and Sedative Effect of Acupuncture Combined with Medicine on Patients Undergiong Cardiac Surgery].
Topics: Acupuncture Analgesia; Analgesia; Analgesics; Cardiac Surgical Procedures; Dexmedetomidine; Electroacupuncture; Heart Rate; Humans; Hypnotics and Sedatives; Morphine; Pain; Pain Management; Respiration, Artificial | 2016 |
Comparison of Intrathecal Dexmedetomidine with Morphine as Adjuvants in Cesarean Sections.
Topics: Adjuvants, Pharmaceutic; Adult; Analgesics; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cesarean Section; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Injections, Spinal; Morphine; Pain; Pregnancy; Pruritus; Shivering | 2016 |
Pain relief during dressing changes of major adult burns: ideal analgesic combination with ketamine.
Topics: Adult; Analgesics; Bandages; Blood Pressure; Burns; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypnotics and Sedatives; Ketamine; Male; Midazolam; Middle Aged; Pain; Pain Measurement; Patient Satisfaction; Respiration; Tramadol; Young Adult | 2010 |
A comparison of dexmedetomidine versus midazolam for sedation, pain and hemodynamic control, during colonoscopy under conscious sedation.
Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Colonoscopy; Conscious Sedation; Consciousness; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Hemodynamics; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Middle Aged; Pain; Pain Measurement; Patient Satisfaction; Prospective Studies; Recovery of Function; Surveys and Questionnaires; Time Factors | 2010 |
Comparison between propofol and dexmedetomidine in postoperative sedation after extensive cervical spine surgery.
Topics: Adult; Aged; Aged, 80 and over; Atropine; Blood Pressure; Cervical Vertebrae; Dexmedetomidine; Dopamine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Middle Aged; Movement; Pain; Postoperative Care; Propofol | 2012 |
Effects of dexmedetomidine on conditioned pain modulation in humans.
Topics: Adult; Analgesics, Non-Narcotic; Cerebral Cortex; Conditioning, Psychological; Dexmedetomidine; Double-Blind Method; Electric Stimulation; Evoked Potentials, Somatosensory; Female; Humans; Male; Pain; Pain Measurement; Tooth | 2012 |
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Topics: Aged; Communication; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Midazolam; Middle Aged; Nurse-Patient Relations; Pain; Pain Measurement; Propofol; Respiration, Artificial; Time Factors | 2012 |
Dexmedetomidine impairs success of patient-controlled sedation in alcoholics during ERCP: a randomized, double-blind, placebo-controlled study.
Topics: Alcoholism; Alfentanil; Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Middle Aged; Pain; Patient Satisfaction; Propofol; Prospective Studies | 2013 |
Preventing pain on injection of rocuronium: two doses of dexmedetomidine.
Topics: Adrenergic alpha-Agonists; Androstanols; Dexmedetomidine; Humans; Injections, Intravenous; Neuromuscular Nondepolarizing Agents; Pain; Rocuronium | 2005 |
Does dexmedetomidine reduce the injection pain due to propofol and rocuronium?
Topics: Adrenergic alpha-Agonists; Adult; Analysis of Variance; Androstanols; Anesthesia, Intravenous; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Humans; Hypnotics and Sedatives; Injections, Intravenous; Middle Aged; Neuromuscular Nondepolarizing Agents; Pain; Pain Measurement; Preoperative Care; Propofol; Prospective Studies; Rocuronium | 2007 |
Thermal antinociception after dexmedetomidine administration in cats: a dose-finding study.
Topics: Analgesics, Non-Narcotic; Animals; Cats; Cross-Over Studies; Dexmedetomidine; Female; Hot Temperature; Injections, Intramuscular; Male; Pain; Pain Measurement | 2008 |
71 other study(ies) available for dexmedetomidine and Pain
| Article | Year |
|---|---|
Changing Pain Management Strategy from Opioid-centric Towards Improve Postoperative Cognitive Dysfunction with Dexmedetomidine.
Topics: Adult; Analgesics, Opioid; Dexmedetomidine; Emergence Delirium; Femoral Neck Fractures; Humans; Pain; Pain Management; Postoperative Cognitive Complications | 2022 |
Procedural Sedation With Dexmedetomidine in Combination With Ketamine in the Emergency Department.
Topics: Anesthetics, Dissociative; Conscious Sedation; Dexmedetomidine; Drug Combinations; Emergency Service, Hospital; Humans; Hypnotics and Sedatives; Ketamine; Pain; Prospective Studies | 2022 |
The feasibility and safety of cocktail treatment of triple anti-inflammatory agents loaded with gelatin sponge promotes early recovery after posterior percutaneous endoscopic cervical discectomy.
Topics: Anti-Inflammatory Agents; Cervical Vertebrae; Dexamethasone; Dexmedetomidine; Diskectomy; Feasibility Studies; Gelatin; Humans; Pain; Retrospective Studies; Ropivacaine; Treatment Outcome; Vitamin B 12 | 2022 |
A sequential allocation study to determine the ED
Topics: Anesthesia, Conduction; Anesthetics, Local; Clonidine; Dexmedetomidine; Double-Blind Method; Humans; Lidocaine; Pain | 2022 |
Effects of dezocine combined with dexmedetomidine on adverse reactions and inflammatory factors in patients undergoing HIPEC after intestinal surgery and its protective effect on the heart in the perioperative period.
Topics: Bridged Bicyclo Compounds, Heterocyclic; C-Reactive Protein; Dexmedetomidine; Digestive System Surgical Procedures; Humans; Hyperthermic Intraperitoneal Chemotherapy; Pain; Perioperative Period; Tetrahydronaphthalenes; Vascular Endothelial Growth Factor A | 2022 |
Anesthetic Effect of Dexmedetomidine in Clinical Functional Neurosurgery.
Topics: Anesthetics; Dexmedetomidine; Humans; Neurosurgery; Neurosurgical Procedures; Pain | 2022 |
Dexmedetomidine and Propofol at End of Life in Pediatric Oncology: Trends in Palliative Sedation Therapy.
Topics: Child; Death; Dexmedetomidine; Humans; Neoplasms; Pain; Palliative Care; Propofol; Prospective Studies; Terminal Care | 2023 |
Structure-based discovery of nonopioid analgesics acting through the α
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Animals; Dexmedetomidine; Drug Design; Drug Discovery; Humans; Ligands; Mice; Molecular Docking Simulation; Pain; Pain Management; Structure-Activity Relationship | 2022 |
Dexmedetomidine alleviates pain in MPTP-treated mice by activating the AMPK/mTOR/NF-κB pathways in astrocytes.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; AMP-Activated Protein Kinases; Animals; Astrocytes; Dexmedetomidine; Disease Models, Animal; Dopaminergic Neurons; Interleukin-6; Mice; Mice, Inbred C57BL; NF-kappa B; Pain; Parkinson Disease; Quality of Life; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha | 2022 |
Novel Use of Intranasal Dexmedetomidine for Refractory Irritability in Pediatric Home Care.
Topics: Administration, Intranasal; Analgesics; Anesthesia; Child; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Pain | 2023 |
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Morphine; Pain; Propofol; Retrospective Studies; Tracheotomy; Ventilators, Mechanical | 2022 |
A comparative study of patient satisfaction about anesthesia with dexmedetomidine for ambulatory dental surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Dexmedetomidine; Humans; Pain; Patient Satisfaction | 2022 |
Impact of dexmedetomidine in conjunction with a weaning protocol on post-surgical opioid use in a neonatal intensive care unit.
Topics: Acetaminophen; Analgesics, Opioid; Clonidine; Dexmedetomidine; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Opioid-Related Disorders; Pain; Retrospective Studies; Weaning | 2023 |
Dexmedetomidine alleviates osteoarthritis inflammation and pain through the CB
Topics: Animals; Dexmedetomidine; Inflammation; Osteoarthritis; Pain; Rats; Synovial Membrane | 2023 |
Long-duration upper extremity surgery under brachial plexus block combined with intravenous dexmedetomidine sedation without an anesthesiologist.
Topics: Anesthesia; Anesthesiologists; Brachial Plexus Block; Dexmedetomidine; Humans; Pain; Retrospective Studies; Upper Extremity | 2023 |
Clinical efficacy of sufentanil combined with dexmedetomidine in patient-controlled subcutaneous analgesia for advanced cancer pain.
Topics: Analgesia, Patient-Controlled; Cancer Pain; Dexmedetomidine; Humans; Neoplasms; Pain; Sufentanil; Treatment Outcome | 2023 |
The risks of sedation and pain control during burn resuscitation: Increased opioids lead to over-resuscitation and hypotension.
Topics: Adult; Analgesics, Opioid; Benzodiazepines; Burns; Dexmedetomidine; Fluid Therapy; Humans; Hypnotics and Sedatives; Hypotension; Middle Aged; Pain; Pain Management; Propofol; Resuscitation; Retrospective Studies | 2023 |
Uterine Artery Embolization for Leiomyomas and Adenomyosis: A Pictorial Essay Based on Our Experience from 1300 Cases.
Topics: Adenomyosis; Adult; Angiography; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Leiomyoma; Magnetic Resonance Imaging; Middle Aged; Pain; Treatment Outcome; Uterine Artery Embolization; Uterine Neoplasms; Uterus | 2019 |
Dexmedetomidine for dyspnoea.
Topics: Dexmedetomidine; Dyspnea; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain | 2023 |
Effectiveness of Quetiapine as a Sedative Adjunct in Mechanically Ventilated Adults Without Delirium.
Topics: Adjuvants, Pharmaceutic; Adult; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pain; Propofol; Quetiapine Fumarate; Respiration, Artificial; Retrospective Studies | 2021 |
Feasibility of Intranasal Dexmedetomidine in Treatment of Postoperative Restlessness, Agitation, and Pain in Geriatric Orthopedic Patients.
Topics: Aged; Aged, 80 and over; Dexmedetomidine; Feasibility Studies; Humans; Pain; Psychomotor Agitation; Retrospective Studies | 2021 |
Evaluation of Dexmedetomidine Dosing in Obese Critically Ill Patients.
Topics: Adolescent; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Respiration, Artificial | 2023 |
Dexmedetomidine relieves formaldehyde-induced pain in rats through both α2 adrenoceptor and imidazoline receptor.
Topics: Animals; Dexmedetomidine; Formaldehyde; Imidazoline Receptors; Male; Nitric Oxide Synthase Type I; Pain; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, G-Protein-Coupled; Signal Transduction | 2017 |
A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China.
Topics: Delirium; Dexmedetomidine; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Pain; Pain Management; Pain Measurement; Surveys and Questionnaires | 2017 |
Dexmedetomidine prolongs levobupivacaine analgesia via inhibition of inflammation and p38 MAPK phosphorylation in rat dorsal root ganglion.
Topics: Animals; Bupivacaine; Dexmedetomidine; Ganglia, Spinal; Inflammation; Levobupivacaine; Male; Neurons, Afferent; p38 Mitogen-Activated Protein Kinases; Pain; Pain Management; Phosphorylation; Rats, Sprague-Dawley | 2017 |
[The impact of goal directed analgesia on mechanical ventilated patients's outcomes in intensive care unit: a clinical observational study].
Topics: Analgesia; China; Critical Care; Delirium; Dexmedetomidine; Drug Administration Schedule; Goals; Humans; Hypnotics and Sedatives; Incidence; Intensive Care Units; Length of Stay; Methohexital; Midazolam; Outcome and Process Assessment, Health Care; Pain; Psychomotor Agitation; Respiration, Artificial; Ventilators, Mechanical | 2017 |
Use of dexmedetomidine in a cardiac intensive care unit.
Topics: Aged; Aged, 80 and over; Critical Care; Delirium; Dexmedetomidine; Drug Utilization; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pain; Prospective Studies; Psychomotor Agitation | 2018 |
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.
Topics: Adult; Aged; Aged, 80 and over; Anxiety; Critical Care; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pain; Propofol; Quality of Life; Respiration, Artificial; Retrospective Studies; Stress Disorders, Post-Traumatic; Sweden; Ventilator Weaning; Young Adult | 2018 |
Blind method regarding the effect of dexmedetomidine on CRBD.
Topics: Dexmedetomidine; Humans; Pain; Postoperative Period; Urinary Bladder; Urinary Catheters | 2018 |
Effect of dexmedetomidine on postoperative delirium in elderly patients undergoing hip fracture surgery.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Anesthesia, General; Delirium; Dexmedetomidine; Female; Hip Fractures; Humans; Hypnotics and Sedatives; Incidence; Male; Middle Aged; Neuroprotective Agents; Pain; Postoperative Complications; Propofol | 2018 |
Evaluation of analgesic interaction between morphine, dexmedetomidine and maropitant using hot-plate and tail-flick tests in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Antiemetics; Dexmedetomidine; Drug Synergism; Drug Therapy, Combination; Male; Morphine; Pain; Pain Measurement; Quinuclidines; Random Allocation; Rats; Rats, Sprague-Dawley | 2019 |
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzodiazepines; Critical Care; Cross-Sectional Studies; Deep Sedation; Delirium; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Fentanyl; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pain; Perception; Professional Practice; Propofol; Psychomotor Agitation; Respiratory Insufficiency | 2019 |
Molecular mechanisms underlying the analgesic property of intrathecal dexmedetomidine and its neurotoxicity evaluation: an in vivo and in vitro experimental study.
Topics: Analgesics; Animals; Blotting, Western; Dexmedetomidine; Immunohistochemistry; In Vitro Techniques; Injections, Spinal; Male; Mice; Nervous System; Pain | 2013 |
The antinociceptive effect of dexmedetomidine modulates spleen cell immunity in mice.
Topics: Analgesics; Animals; Dexmedetomidine; Formaldehyde; Immunity; Interleukin-10; Killer Cells, Natural; Lymphocytes; Mice; Pain; Spleen | 2014 |
Dexmedetomidine #280.
Topics: Administration, Intravenous; Conscious Sedation; Costs and Cost Analysis; Dexmedetomidine; Humans; Hypnotics and Sedatives; Pain; Pain Management; Respiration, Artificial; Terminal Care | 2014 |
Dexmedetomidine produced analgesic effect via inhibition of HCN currents.
Topics: Analgesics, Non-Narcotic; Animals; Dexmedetomidine; HEK293 Cells; Hot Temperature; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice, Inbred C57BL; Mice, Knockout; Pain; Potassium Channels | 2014 |
Prepubertal gonadectomy in cats: different injectable anaesthetic combinations and comparison with gonadectomy at traditional age.
Topics: Anesthesia; Anesthetics; Animals; Buprenorphine; Cats; Dexmedetomidine; Female; Injections, Intramuscular; Ketamine; Medetomidine; Orchiectomy; Ovariectomy; Pain; Random Allocation; Sexual Maturation | 2015 |
Dexmedetomidine and hydromorphone: a novel pain management strategy for the oncology ward setting during anti-GD2 immunotherapy for high-risk neuroblastoma in children.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Antibodies, Monoclonal; Child; Child, Preschool; Dexmedetomidine; Drug Therapy, Combination; Female; Follow-Up Studies; Gangliosides; Humans; Hydromorphone; Immunotherapy; Male; Neuroblastoma; Pain; Pain Management; Prognosis | 2015 |
Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Anemia, Sickle Cell; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Hand Strength; Humans; Hypnotics and Sedatives; Mice; Mice, Transgenic; Pain; Pain Measurement; Vocalization, Animal; Wakefulness | 2015 |
Dexmedetomidine as an Adjuvant to Analgesic Strategy During Vaso-Occlusive Episodes in Adolescents with Sickle-Cell Disease.
Topics: Adolescent; Analgesics, Non-Narcotic; Anemia, Sickle Cell; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Male; Pain; Pain Management; Pain Measurement | 2015 |
The Use of Dexmedetomidine in Pediatric Palliative Care: A Preliminary Study.
Topics: Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Cohort Studies; Dexmedetomidine; Female; Heart Diseases; Humans; Hypnotics and Sedatives; Infant; Male; Pain; Palliative Care | 2017 |
Analgesic effect of dexmedetomidine in a patient with herpetic stomatitis after living-donor lung transplantation.
Topics: Adult; Analgesics, Non-Narcotic; Dexmedetomidine; Female; Humans; Living Donors; Lung Transplantation; Pain; Stomatitis, Herpetic; Treatment Outcome | 2008 |
Dexmedetomidine and ST-91 analgesia in the formalin model is mediated by alpha2A-adrenoceptors: a mechanism of action distinct from morphine.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Analgesics; Animals; Clonidine; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Formaldehyde; Gene Expression Regulation; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Neurokinin-1; Substance P | 2008 |
Effects of variation in the human alpha2A- and alpha2C-adrenoceptor genes on cognitive tasks and pain perception.
Topics: Adrenergic alpha-Agonists; Adult; Cognition; Cold Temperature; Dexmedetomidine; Female; Genetic Variation; Genotype; Humans; Hypnotics and Sedatives; Male; Memory; Pain; Pain Measurement; Pressure; Psychomotor Performance; Reaction Time; Receptors, Adrenergic, alpha-2; Tandem Mass Spectrometry; Young Adult | 2010 |
The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics, Non-Narcotic; Animals; Catheterization; Clonidine; Colon; Data Interpretation, Statistical; Dexmedetomidine; Dose-Response Relationship, Drug; Injections, Intravenous; Male; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Physical Stimulation; Quinolizines; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Rectum; Yohimbine | 2009 |
Effects of alpha-adrenergic agonists on pain modulation in diffuse noxious inhibitory control.
Topics: Adrenergic alpha-Agonists; Adrenergic Antagonists; Animals; Dexmedetomidine; Electromyography; Injections, Spinal; Male; Nerve Fibers, Unmyelinated; Nerve Net; Neural Inhibition; Nociceptors; Pain; Phentolamine; Phenylephrine; Rats; Rats, Wistar | 2009 |
Neuroprotective effects of a combination of dexmedetomidine and hypothermia after incomplete cerebral ischemia in rats.
Topics: Animals; Brain; Brain Ischemia; Carbon Dioxide; Cell Survival; Cerebrovascular Circulation; Combined Modality Therapy; Consciousness; Dexmedetomidine; Hypnotics and Sedatives; Hypothermia, Induced; Male; Muscle Tonus; Nervous System Diseases; Neuroprotective Agents; Pain; Postural Balance; Rats; Rats, Sprague-Dawley; Walking | 2010 |
Midazolam enhances the analgesic properties of dexmedetomidine in the rat.
Topics: Analgesia; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Hypnotics and Sedatives; Male; Midazolam; Pain; Rats | 2010 |
Evaluation of dexmedetomidine versus propofol-based sedation therapy in mechanically ventilated cardiac surgery patients at a tertiary academic medical center.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Clinical Protocols; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Pain; Pain Management; Palliative Care; Postoperative Care; Propofol; Research Design; Respiration, Artificial; Treatment Outcome | 2010 |
Dexmedetomidine and clonidine inhibit the function of Na(v)1.7 independent of α(2)-adrenoceptor in adrenal chromaffin cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Binding Sites; Cattle; Cells, Cultured; Chromaffin Cells; Clonidine; Cyclopentanes; Dexmedetomidine; Imidazoles; Lidocaine; Organophosphorus Compounds; Ouabain; Pain; Receptors, Adrenergic, alpha-2; Scorpion Venoms; Sodium; Sodium Channels; Tetrodotoxin; Veratridine; Yohimbine | 2011 |
Dexmedetomidine for co-analgesia in chemotherapy-induced severe enterocolitis.
Topics: Adrenal Gland Neoplasms; Analgesics, Non-Narcotic; Analgesics, Opioid; Antineoplastic Agents; Child, Preschool; Dexmedetomidine; Enterocolitis; Female; Humans; Hydromorphone; Infusions, Intravenous; Neuroblastoma; Pain; Pain Measurement | 2011 |
Ephedrine enhances the antinociceptive effect of dexmedetomidine in mice.
Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Drug Synergism; Drug Therapy, Combination; Ephedrine; Female; Male; Mice; Motor Activity; Nociceptors; Pain; Pain Threshold | 2011 |
Investigation of modulation of the alpha-2 receptor in tetrahydropalmatine (THP) analgesia in male Sprague-Dawley rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesia; Analgesics; Analysis of Variance; Animals; Berberine Alkaloids; Corydalis; Dexmedetomidine; Herb-Drug Interactions; Hot Temperature; Hypnotics and Sedatives; Male; Pain; Pain Threshold; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Yohimbine | 2009 |
Effects of propofol and dexmedetomidine on motor coordination and analgesia: a comparative analysis.
Topics: Analgesics; Animals; Behavior, Animal; Dexmedetomidine; Disease Models, Animal; Hot Temperature; Male; Motor Skills; Pain; Pain Measurement; Pain Threshold; Propofol; Rats; Reaction Time; Time Factors | 2012 |
Pharmacological mechanisms involved in the antinociceptive effects of dexmedetomidine in mice.
Topics: Analgesics; Animals; Dexmedetomidine; Mice; Nitric Oxide; Pain; Pain Measurement; Receptors, Adrenergic, alpha-2 | 2014 |
Dexmedetomidine in pediatrics: controlled studies needed.
Topics: Adolescent; Adult; Child; Child, Preschool; Dexmedetomidine; Humans; Infant; Pain; Perioperative Care | 2004 |
Synergistic and additive interactions of the cannabinoid agonist CP55,940 with mu opioid receptor and alpha2-adrenoceptor agonists in acute pain models in mice.
Topics: Acute Disease; Adrenergic alpha-Agonists; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Cannabinoids; Cyclohexanols; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Male; Mice; Morphine; Pain; Pain Measurement; Receptors, Opioid, mu | 2005 |
The prevention of pain from injection of propofol by dexmedetomidine and comparison with lidocaine.
Topics: Dexmedetomidine; Humans; Injections, Intravenous; Lidocaine; Pain; Propofol | 2005 |
[Anesthetic management of awake coronary artery bypass grafting using dexmedetomidine--high-dose administration and pharmacokinetic simulation].
Topics: Aged; Analgesics, Non-Narcotic; Anesthesia, Epidural; Anesthetics, Local; Coronary Artery Bypass; Dexmedetomidine; Humans; Infusions, Intravenous; Intraoperative Care; Intraoperative Complications; Male; Pain; Wakefulness | 2006 |
Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Dexmedetomidine; Drug Administration Routes; Drug Synergism; Furans; Injections, Intraperitoneal; Male; Pain; Pain Measurement; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2007 |
Intrathecal infusion therapy with dexmedetomidine-supplemented morphine in cancer pain.
Topics: Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Drug Therapy, Combination; Humans; Male; Morphine; Neoplasms; Pain; Recurrence | 2007 |
Characterization of spinal alpha-adrenergic modulation of nociceptive transmission and hyperalgesia throughout postnatal development in rats.
Topics: Adrenergic alpha-Agonists; Age Factors; Analgesics; Animals; Animals, Newborn; Dexmedetomidine; Dose-Response Relationship, Drug; Electromyography; Heart Rate; Hindlimb; Humans; Infant; Infant, Newborn; Injections, Epidural; Mustard Plant; Nerve Fibers; Pain; Pain Threshold; Plant Oils; Rats; Spinal Cord Injuries | 2007 |
Current state of sedation/analgesia care in dentistry.
Topics: Anesthesia, Dental; Conscious Sedation; Dental Anxiety; Dentistry; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Pain; Patient Satisfaction; Propofol | 2007 |
Current world literature.
Topics: Anesthesiology; Dexmedetomidine; Emergency Service, Hospital; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Nerve Block; Pain; Pain Management; Propofol | 2007 |
Neonates have a spinal alpha receptor too, as do adults.
Topics: Adrenergic alpha-Agonists; Adult; Age Factors; Analgesics; Animals; Animals, Newborn; Dexmedetomidine; Humans; Infant, Newborn; Injections, Spinal; Pain; Pain Measurement; Pain Threshold; Phenotype; Rats; Receptors, Adrenergic, alpha; Species Specificity | 2007 |
Analysis of the antinociceptive effect of systemic administration of tramadol and dexmedetomidine combination on rat models of acute and neuropathic pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Constriction, Pathologic; Dexmedetomidine; Drug Combinations; Hot Temperature; Hyperalgesia; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Postural Balance; Rats; Rats, Wistar; Reaction Time; Sciatica; Time Factors; Tramadol | 2007 |
Dexmedetomidine relieves pain associated with acute sickle cell crisis.
Topics: Adult; Analgesics, Non-Narcotic; Anemia, Sickle Cell; Dexmedetomidine; Female; Humans; Male; Pain; Pain Measurement; Treatment Outcome | 2007 |
The efficacy and neurotoxicity of dexmedetomidine administered via the epidural route.
Topics: Adrenergic alpha-Agonists; Anesthesia, Epidural; Anesthetics, Local; Animals; Blood Gas Analysis; Blood Pressure; Dexmedetomidine; Heart Rate; Injections, Epidural; Lidocaine; Motor Activity; Myelin Sheath; Pain; Pain Measurement; Rabbits; Random Allocation; Treatment Outcome | 2008 |
Attenuation of ascending nociceptive signals to the rostroventromedial medulla induced by a novel alpha2-adrenoceptor agonist, MPV-2426, following intrathecal application in neuropathic rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Behavior, Animal; Dexmedetomidine; Electrophysiology; Hot Temperature; Imidazoles; Indans; Injections, Spinal; Male; Medulla Oblongata; Pain; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Wistar; Reaction Time; Signal Transduction | 2000 |
Effects of radolmidine, a novel alpha2 -adrenergic agonist compared with dexmedetomidine in different pain models in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Area Under Curve; Constriction; Dexmedetomidine; Imidazoles; Indans; Inflammation; Injections, Spinal; Male; Models, Biological; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Spinal Nerves; Structure-Activity Relationship | 2000 |
Contribution of alpha(2) receptor subtypes to nerve injury-induced pain and its regulation by dexmedetomidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analgesics; Animals; Dexmedetomidine; Female; Genotype; Guanethidine; Male; Mice; Pain; Peripheral Nerve Injuries; Point Mutation; Receptors, Adrenergic, alpha-2; Sympathectomy, Chemical; Sympatholytics | 2001 |