dexmedetomidine has been researched along with Nerve Pain in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (62.50) | 24.3611 |
| 2020's | 9 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, J; Hu, W; Huang, T; Li, Y; Wang, Z; Xu, Y; Yang, F; Yu, D; Zong, L | 1 |
| He, M; Xu, S; Zhang, X; Zhao, X; Zheng, X; Zhu, Z | 1 |
| Chen, Y; Cui, J; Li, Y; Mei, Y; Mu, Y; Yu, L; Zhu, D | 1 |
| Kong, Y; Pang, J; Pei, R; Wang, X; Wang, Z; Zhang, S; Zhuang, P | 1 |
| Li, L; Wang, F; Yao, L; Zhang, Z | 1 |
| Xun, S; Zheng, R | 1 |
| Chen, J; Chen, T; Chi, X; Deng, Y; Liu, P; Tan, F; Tian, J; Zheng, L | 1 |
| Bai, L; Dou, Z; Huang, Y; Li, L; Li, S; Li, Y; Lv, Y; Zhao, E | 1 |
| Cui, X; Li, X; Yu, H; Yu, T; Zhang, W | 1 |
| Fang, J; Fu, S; Li, M; Yuan, X | 1 |
| Chen, H; Jiang, K; Wang, J; Wu, JR; Yao, YY; Zhang, DX; Zhang, MM; Zhou, B | 1 |
| Bai, X; Chen, X; Huang, J; Huang, Z; Nie, B; Ouyang, H; Zeng, W; Zhang, S; Zheng, Y | 1 |
| Chen, J; Li, H; Li, N; Lim, G; Ma, W; McCabe, MF; Yang, Y; Zhao, W | 1 |
| Liu, K; Meng, Q; Shi, L; Xia, Z; Xiao, Y; Yang, Y | 1 |
| Feng, YX; Gu, R; Li, T; Li, W; Zhang, F; Zhang, M; Zhang, YL | 1 |
| Li, SS; Xiong, YC; Xu, H; Yang, JL; Zhang, WS; Zhang, YQ | 1 |
| Choi, JI; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Chen, ZY; Liu, ZX; Miao, B; Wu, JR; Zhou, TT | 1 |
| O'Neil, T; Rodgers, PE; Shultz, C | 1 |
| Brown, S; Hilliard, N; Mitchinson, S | 1 |
| Abdel-Sater, KA; Farghaly, HS; Mahmoud, AM | 1 |
| Deng, R; Hu, Z; Huang, X; Tu, W | 1 |
| Gao, XM; Leng, YF; Wang, SX; Xing, YH | 1 |
| Kimura, M; Obata, H; Saito, S | 1 |
24 other study(ies) available for dexmedetomidine and Nerve Pain
| Article | Year |
|---|---|
Dexmedetomidine attenuates haemorrhage-induced thalamic pain by inhibiting the TLR4/NF-κB/ERK1/2 pathway in mice.
Topics: Analgesics, Non-Narcotic; Animals; Dexmedetomidine; Disease Models, Animal; Hemorrhage; Inflammation; Male; MAP Kinase Signaling System; Mice; Neuralgia; NF-kappa B; Signal Transduction; Toll-Like Receptor 4 | 2021 |
A New Potential Antidepressant: Dexmedetomidine Alleviates Neuropathic Pain-Induced Depression by Increasing Neurogenesis in the Hippocampus.
Topics: Animals; Antidepressive Agents; Bromodeoxyuridine; Chronic Pain; Corticosterone; Depression; Dexmedetomidine; Hippocampus; Mice; Neuralgia; Neurogenesis; Sucrose | 2022 |
Perisciatic Nerve Dexmedetomidine Alleviates Spinal Oxidative Stress and Improves Peripheral Mitochondrial Dynamic Equilibrium in a Neuropathic Pain Mouse Model in an AMPK-Dependent Manner.
Topics: AMP-Activated Protein Kinases; Animals; Dexmedetomidine; Disease Models, Animal; Membrane Proteins; Mice; Mitochondrial Dynamics; Nerve Tissue Proteins; Neuralgia; Oxidative Stress | 2022 |
The effect of dexmedetomidine on expression of neuronal nitric oxide synthase in spinal dorsal cord in a rat model with chronic neuropathic pain.
Topics: Animals; Dexmedetomidine; Hyperalgesia; Male; Neuralgia; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Spinal Cord | 2023 |
Knock-down of JAK2 and PTEN on pain behavior in rat model of trigeminal neuropathic pain.
Topics: Animals; Dental Implants; Dexamethasone; Dexmedetomidine; Disease Models, Animal; Gene Knockdown Techniques; Hyperalgesia; Janus Kinase 2; Male; Neuralgia; Pain Measurement; PTEN Phosphohydrolase; Rats; Rats, Sprague-Dawley; Trigeminal Neuralgia | 2019 |
Dexmedetomidine alleviates neuropathic pain by regulating JAK/STAT pathway in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Constriction, Pathologic; Dexmedetomidine; Gene Expression Regulation; Janus Kinase 1; Neuralgia; Rats; Rats, Sprague-Dawley; STAT Transcription Factors | 2020 |
Dexmedetomidine alleviated neuropathic pain in dorsal root ganglion neurons by inhibition of anaerobic glycolysis activity and enhancement of ROS tolerance.
Topics: Acetylcysteine; Anaerobiosis; Animals; Apoptosis; Cells, Cultured; Dexmedetomidine; Disease Models, Animal; Ganglia, Spinal; Glucose; Glycolysis; Humans; Hydrogen Peroxide; Neuralgia; Neurons; Primary Cell Culture; Rats; Reactive Oxygen Species | 2020 |
Dexmedetomidine Alleviates CCI-Induced Neuropathic Pain via Inhibiting HMGB1-Mediated Astrocyte Activation and the TLR4/NF-κB Signaling Pathway in Rats.
Topics: Animals; Astrocytes; Dexmedetomidine; HMGB1 Protein; Male; Neuralgia; Rats, Sprague-Dawley; Sciatic Nerve; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
Analgesic effect of dexmedetomidine in rats after chronic constriction injury by mediating microRNA-101 expression and the E2F2-TLR4-NF-κB axis.
Topics: Analgesics; Animals; Constriction; Dexmedetomidine; E2F2 Transcription Factor; Male; MicroRNAs; Neuralgia; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4 | 2020 |
Effects of dexmedetomidine on behavior of and expressions of spinal cord P38 MAPK and spinal cord-related cytokines in rats with neuropathic pain.
Topics: Animals; Cytokines; Dexmedetomidine; Hyperalgesia; Neuralgia; p38 Mitogen-Activated Protein Kinases; Rats; Spinal Cord | 2022 |
Local injection to sciatic nerve of dexmedetomidine reduces pain behaviors, SGCs activation, NGF expression and sympathetic sprouting in CCI rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Animals; Chronic Pain; Dexmedetomidine; Disease Models, Animal; Male; Microglia; Nerve Growth Factor; Neuralgia; Neurons; Random Allocation; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord Dorsal Horn | 2017 |
Synergistic Interaction Between Dexmedetomidine and Ulinastatin Against Vincristine-Induced Neuropathic Pain in Rats.
Topics: Analgesics, Non-Narcotic; Animals; Dexmedetomidine; Disease Models, Animal; Drug Synergism; Ganglia, Spinal; Glycoproteins; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Interleukin-10; Male; Neuralgia; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Specific Pathogen-Free Organisms; Touch; Trypsin Inhibitors; Vincristine | 2017 |
Different effects of dexmedetomidine and midazolam on the expression of NR2B and GABAA-α1 following peripheral nerve injury in rats.
Topics: Animals; Dexmedetomidine; Disease Models, Animal; Hedgehog Proteins; Hyperalgesia; Male; Midazolam; Neuralgia; Peripheral Nerve Injuries; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord Dorsal Horn; Thalamus | 2018 |
Dexmedetomidine relieves neuropathic pain by inhibiting hyperpolarization-activated cyclic nucleotide-gated currents in dorsal root ganglia neurons.
Topics: Analgesics, Non-Narcotic; Animals; Cells, Cultured; Dexmedetomidine; Ganglia, Spinal; HEK293 Cells; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Male; Membrane Potentials; Neuralgia; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2018 |
[Dexmedetomidine suppresses mechanical allodynia by inhibiting hyperpolarization-activated inward current].
Topics: Animals; Dexmedetomidine; Ganglia, Spinal; Hyperalgesia; Neuralgia; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley | 2018 |
Involvement of protein kinase B/Akt in analgesic effect of dexmedetomidine on neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Dexmedetomidine; Neuralgia; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction | 2013 |
The role of alpha-2 adrenoceptor subtype in the antiallodynic effect of intraplantar dexmedetomidine in a rat spinal nerve ligation model.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Animals; Axotomy; Dexmedetomidine; Disease Models, Animal; Hyperalgesia; Ligation; Male; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Spinal Nerves | 2013 |
Effects of dexmedetomidine on P2X4Rs, p38-MAPK and BDNF in spinal microglia in rats with spared nerve injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Dexmedetomidine; Disease Models, Animal; Fluorescent Antibody Technique; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Microglia; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Threshold; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Sciatic Nerve; Spinal Cord | 2014 |
Dexmedetomidine as adjuvant therapy for acute postoperative neuropathic pain crisis.
Topics: Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chemotherapy, Adjuvant; Dexmedetomidine; Humans; Male; Neuralgia; Pain, Postoperative; Sarcoma | 2014 |
A case report of dexmedetomidine used to treat intractable pain and delirium in a tertiary palliative care unit.
Topics: Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Female; Humans; Infusions, Subcutaneous; Middle Aged; Neuralgia; Pain, Intractable; Palliative Care; Uterine Cervical Neoplasms | 2015 |
Effect of dexmedetomidine and cold stress in a rat model of neuropathic pain: Role of interleukin-6 and tumor necrosis factor-α.
Topics: Animals; Body Weight; Cold-Shock Response; Dexmedetomidine; Disease Models, Animal; Hyperalgesia; Interleukin-6; Male; Neuralgia; Nociception; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Sympathetic Nervous System; Tumor Necrosis Factor-alpha | 2016 |
Dexmedetomidine reduces neuropathic pain in a rat model of skin/muscle incision and retraction.
Topics: Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Dermatologic Surgical Procedures; Dexmedetomidine; Drug Administration Schedule; Drug Therapy, Combination; Injections; Male; Muscle, Skeletal; Neuralgia; Pain Measurement; Pain, Postoperative; Preoperative Care; Random Allocation; Rats; Rats, Sprague-Dawley; Ropivacaine; Thigh; Treatment Outcome | 2017 |
[Clonidine and dexmedetomidine's effect on the altered expressions of growth associated protein-43 mRNA in rat dorsal root ganglion during the development of chronic neuropathic pain].
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Dexmedetomidine; Ganglia, Spinal; GAP-43 Protein; Male; Neuralgia; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2012 |
Dexmedetomidine decreases hyperalgesia in neuropathic pain by increasing acetylcholine in the spinal cord.
Topics: Acetylcholine; Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Hyperalgesia; Male; Neuralgia; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Spinal Cord | 2012 |