dexmedetomidine has been researched along with Myocardial Infarction in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (17.86) | 29.6817 |
| 2010's | 8 (28.57) | 24.3611 |
| 2020's | 15 (53.57) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, S; Chen, H; Chen, Y; Xu, X; Yang, Z; Yin, C | 1 |
| Jiang, X; Yan, M | 1 |
| Lu, SJ; Qi, QL; Wang, HY; Zhang, YJ | 1 |
| Adams, JM; Albright, J; Aziz, A; Beaulieu, RJ; Heidenreich, MJ; Patel, SH; Pawlikowski, AM; Sundararaghavan, VL | 1 |
| Chen, K; Guo, P; Han, M; Liu, X; Qing, J; Yang, F; Yi, H | 1 |
| Chen, H; Chen, Y; Xu, W; Yang, Z; Zhou, T | 1 |
| Behmenburg, F; Bunte, S; Heinen, A; Hollmann, MW; Huhn, R; Majewski, N; Mathes, A; Raupach, A; Stroethoff, M | 1 |
| Dai, D; Han, H; Hu, J; Lu, L; Tao, G; Zhang, R; Zhu, J | 1 |
| Li, J; Li, K; Li, L; Zhao, Y; Zhou, N | 1 |
| Li, Y; Ma, W; Ren, X; Wang, Y; Yang, K; Zhang, X; Zhong, M; Zhuang, Y | 1 |
| Chang, JH; Jin, MM; Liu, JT | 1 |
| He, L; Qian, J; Song, N; Wang, Z; Xiong, W; Yang, Y; Zhou, R | 1 |
| Hou, X; Kong, M; Ni, H; Shao, Z; Shen, Q | 1 |
| Duan, JS; Ge, S; Gong, Q; Shen, Z; Sun, T; Wu, Y; Zhang, Y | 1 |
| Ainiwaer, Y; Geng, Q; He, B; Li, X; Lin, L; Zhang, B; Zhang, J | 1 |
| Liang, R; Qian, J; Qu, Y; Song, N; Wang, Z; Xiong, W; Yang, Y; Zhou, R | 1 |
| Li, H; Liu, J; Shi, H | 1 |
| Behmenburg, F; Berger, MM; Heinen, A; Hollmann, MW; Huhn, R; Mathes, A; Pickert, E | 1 |
| Cheng, XY; Gao, Q; Gu, XY; Hu, J; Li, XH; Li, ZH; Meng, Y; Wang, Y | 1 |
| Beattie, WS; Duncan, D; Sankar, A; Wijeysundera, DN | 1 |
| Chen, H; Deng, L; Wang, G; Wei, N; Zhang, Z | 1 |
| Cheng, XY; Gao, Q; Gu, XY; Li, XH; Zhang, Y; Zong, QF | 1 |
| Adachi, YU; Katoh, T; Mimuro, S; Sano, H; Sato, S; Suzuki, A; Uraoka, M; Yu, S | 1 |
| Levy, JH; Ruesch, S | 1 |
| Beattie, WS; Naik, JS; Wijeysundera, DN | 1 |
| Kulkarni, A; Price, G; Saxena, M; Skowronski, G | 1 |
| Iwasaki, H; Kunisawa, T; Nagata, O | 1 |
| Kurita, T; Mochizuki, T; Morita, K; Okada, H; Sato, S | 1 |
2 review(s) available for dexmedetomidine and Myocardial Infarction
| Article | Year |
|---|---|
Alpha-2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoperative Complications; Myocardial Infarction; Postoperative Complications; Randomized Controlled Trials as Topic; Stress, Physiological; Stroke; Surgical Procedures, Operative | 2018 |
Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis.
Topics: Adrenergic alpha-Agonists; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Clonidine; Dexmedetomidine; Humans; Imidazoles; Myocardial Infarction; Perioperative Care; Preoperative Care; Randomized Controlled Trials as Topic; Registries | 2003 |
1 trial(s) available for dexmedetomidine and Myocardial Infarction
| Article | Year |
|---|---|
Effect of Dexmedetomidine on Perioperative Hemodynamics and Myocardial Protection in Thoracoscopic-Assisted Thoracic Surgery.
Topics: Aged; Analgesics, Non-Narcotic; Blood Pressure Determination; Cardiotonic Agents; Creatine Kinase, MB Form; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Humans; Length of Stay; Male; Monitoring, Intraoperative; Myocardial Infarction; Natriuretic Peptide, Brain; Pain, Postoperative; Peptide Fragments; Preoperative Care; Thoracic Surgery, Video-Assisted; Treatment Outcome; Troponin I | 2021 |
25 other study(ies) available for dexmedetomidine and Myocardial Infarction
| Article | Year |
|---|---|
Dexmedetomidine Preconditioning Reduces Myocardial Ischemia-Reperfusion Injury in Rats by Inhibiting the PERK Pathway.
Topics: Animals; Dexmedetomidine; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Reperfusion Injury; Signal Transduction | 2021 |
Comparing the impact on the prognosis of acute myocardial infarction critical patients of using midazolam, propofol, and dexmedetomidine for sedation.
Topics: Aged; Aged, 80 and over; Coronary Care Units; Critical Illness; Databases, Factual; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Myocardial Infarction; Propofol; Respiration, Artificial; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2021 |
Effects of electroacupuncture with dexmedetomidine on myocardial ischemia/reperfusion injury in rats.
Topics: Adenosine Triphosphate; Animals; Dexmedetomidine; Electroacupuncture; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2022 |
Outcomes of Dexmedetomidine with Local Regional Anesthesia in Carotid Endarterectomy.
Topics: Anesthesia, Conduction; Dexmedetomidine; Endarterectomy, Carotid; Humans; Myocardial Infarction; Pain, Postoperative; Retrospective Studies; Stroke; Treatment Outcome | 2023 |
Dexmedetomidine alleviates myocardial ischemia-reperfusion injury by down-regulating miR-34b-3p to activate the Jagged1/Notch signaling pathway.
Topics: Animals; Apoptosis; Dexmedetomidine; Jagged-1 Protein; MicroRNAs; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Receptors, Notch; Signal Transduction | 2023 |
Dexmedetomidine Preconditioning Attenuates Myocardial Ischemia/Reperfusion Injury in Rats by Suppressing Mitophagy Via Activating Α2-Adrenergic Receptor.
Topics: Animals; Beclin-1; Dexmedetomidine; Mitophagy; Myocardial Infarction; Myocardial Reperfusion Injury; Protein Kinases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Adrenergic; Reperfusion Injury; Ubiquitin-Protein Ligases | 2023 |
Characteristics of Dexmedetomidine Postconditioning in the Field of Myocardial Ischemia-Reperfusion Injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Isolated Heart Preparation; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats, Wistar; Time Factors; Ventricular Function, Left | 2020 |
Dexmedetomidine improves cardiac function and protects against maladaptive remodeling following myocardial infarction.
Topics: Animals; Apoptosis; Biomarkers; Biopsy; Cardiotonic Agents; Dexmedetomidine; Disease Models, Animal; Fibrosis; Male; Mice; Myocardial Infarction; Oxidative Stress; Superoxide Dismutase; Ventricular Dysfunction, Left; Ventricular Function; Ventricular Remodeling | 2019 |
Dexmedetomidine Attenuates Myocardial Ischemia-Reperfusion Injury in Diabetes Mellitus by Inhibiting Endoplasmic Reticulum Stress.
Topics: Animals; Apoptosis; Cell Line; Creatine Kinase, MB Form; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Fibrosis; Heat-Shock Proteins; Male; Membrane Glycoproteins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Protein Disulfide-Isomerases; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor CHOP; Troponin T | 2019 |
Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Autophagy; Dexmedetomidine; Disease Models, Animal; Inflammation Mediators; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction; Sirtuin 1; TOR Serine-Threonine Kinases | 2020 |
Dexmedetomidine pretreatment protects the heart against apoptosis in ischemia/reperfusion injury in diabetic rats by activating PI3K/Akt signaling in vivo and in vitro.
Topics: Animals; Apoptosis; Cardiotonic Agents; Dexmedetomidine; Diabetes Mellitus, Experimental; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2020 |
Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway.
Topics: Animals; Apoptosis; Cell Hypoxia; Cell Line; Dexmedetomidine; Disease Models, Animal; Gene Expression Regulation; Interleukin-1 Receptor-Associated Kinases; Male; MicroRNAs; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; TNF Receptor-Associated Factor 6 | 2021 |
Involvement of GPR30 in protection effect of Dexmedetomidine against myocardial ischemia/reperfusion injury in rat via AKT pathway.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Survival; Cells, Cultured; Chromones; Dexmedetomidine; Disease Models, Animal; Drug Synergism; Gene Knockdown Techniques; Male; Morpholines; Myocardial Infarction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Transfection | 2021 |
Dexmedetomidine alleviates cardiomyocyte apoptosis and cardiac dysfunction may be associated with inhibition of RhoA/ROCK pathway in mice with myocardial infarction.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Dexmedetomidine; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2021 |
Dexmedetomidine Attenuates Myocardial Injury Induced by Renal Ischemia/Reperfusion by Inhibiting the HMGB1-TLR4-MyD88-NF-κB Signaling Pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; HMGB1 Protein; Ischemia; Male; Myeloid Differentiation Factor 88; Myocardial Infarction; NF-kappa B; Rats; Rats, Wistar; Reperfusion Injury; Toll-Like Receptor 4 | 2021 |
Dexmedetomidine preconditioning mitigates myocardial ischemia/reperfusion injury via inhibition of mast cell degranulation.
Topics: Animals; Apoptosis; Arrhythmias, Cardiac; Cardiotonic Agents; Cell Degranulation; Cell Line; Cell Proliferation; Dexmedetomidine; Hemodynamics; Ischemic Preconditioning; Male; Mast Cells; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley | 2021 |
The Cardioprotective Effect of Dexmedetomidine in Rats Is Dose-Dependent and Mediated by BKCa Channels.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cardiotonic Agents; Dexmedetomidine; Dose-Response Relationship, Drug; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Male; Myocardial Infarction; Organ Culture Techniques; Rats; Rats, Wistar; Treatment Outcome | 2017 |
[Effect of dexmedetomidine postconditioning on myocardial ischemia-reperfusion injury and inflammatory response in diabetic rats].
Topics: Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Inflammation; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Sprague-Dawley | 2017 |
The cardioprotective effect of dexmedetomidine on regional ischemia/reperfusion injury in type 2 diabetic rat hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Arrhythmias, Cardiac; Cytoprotection; Dexmedetomidine; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Heart Rate; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Rats, Sprague-Dawley; Troponin T | 2019 |
Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury.
Topics: Animals; bcl-2-Associated X Protein; Biomarkers; Cardiotonic Agents; Caspase 3; Creatine Kinase, MB Form; Dexmedetomidine; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Signal Transduction; Superoxide Dismutase | 2016 |
Deterioration of myocardial injury due to dexmedetomidine administration after myocardial ischaemia.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Coronary Circulation; Dexmedetomidine; Hemodynamics; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Sprague-Dawley; Yohimbine | 2010 |
Treatment of persistent tachycardia with dexmedetomidine during off-pump cardiac surgery.
Topics: Adrenergic alpha-Agonists; Aged; Blood Pressure; Cardiac Surgical Procedures; Dexmedetomidine; Humans; Male; Myocardial Infarction; Myocardial Revascularization; Tachycardia | 2002 |
Difficult extubation: calming the sympathetic storm.
Topics: Aged; Conscious Sedation; Device Removal; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Myocardial Infarction; Propofol; Pulmonary Edema; Stress, Physiological; Sympathetic Nervous System; Tachycardia; Ventricular Dysfunction, Left | 2004 |
[Postoperative management and extubation under sedation using dexmedetomidine in a patient with old myocardial infarction after carotid endarterectomy].
Topics: Conscious Sedation; Dexmedetomidine; Endarterectomy, Carotid; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Middle Aged; Myocardial Infarction; Postoperative Care | 2005 |
The cardioprotective effect of dexmedetomidine on global ischaemia in isolated rat hearts.
Topics: Adrenergic alpha-Agonists; Animals; Coronary Circulation; Dexmedetomidine; Disease Models, Animal; Heart Arrest; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Treatment Outcome; Ventricular Function, Left | 2007 |