dexmedetomidine has been researched along with Muscle Contraction in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 14 (66.67) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Chikuda, M; Sato, K | 1 |
| Li, SP; Zhao, Y; Zhou, XL | 1 |
| Bruns, TM; Kennedy, E; Lester, PA; Martin, T; Ouyang, Z; Xu, JJ; Yousuf, Z | 1 |
| Emala, CW; Groeben, H; Kim, B; Mikami, M; Worgall, TS; Zhang, Y | 1 |
| Li, ZM; Liu, XR; Tan, XQ; Wei, JC; Yang, Y; Zhou, J; Zhou, SZ | 1 |
| Bock, JM; Casey, DP; Feider, AJ; Hanada, S; Hughes, WE; Iwamoto, E; Kruse, NT; Ueda, K | 1 |
| Acheson, AG; Dashwood, MR; Eames, T; Gruss, H; Henry, Y; Rayment, SJ; Scholefield, JH; Simpson, JA; Wilson, VG | 1 |
| Andtbacka, RH; Gifford, JR; Hyngstrom, JR; Ives, SJ; Mueller, MT; Park, SY; Richardson, RS; Treiman, GS; Trinity, JD; Ward, C | 1 |
| Byon, HJ; Eun, SY; Jin, H; Kim, HJ; Kim, W; Nam, IK; Ok, SH; Sohn, JT | 1 |
| Baik, J; Cho, H; Choi, MJ; Kim, W; Lee, HK; Nam, IK; Ok, SH; Sohn, JT; Yu, J | 1 |
| Cho, H; Choi, MJ; Chung, YK; Kim, WH; Kwon, SC; Lee, HK; Ok, SH; Park, J; Shin, IW; Sohn, JT; Yu, J | 1 |
| Baik, J; Han, JY; Hong, JM; Kwon, SC; Oh, J; Ok, SH; Sohn, JT | 1 |
| Byon, HJ; Cho, Y; Han, JY; Kang, S; Lee, SH; Ok, SH; Sohn, JT | 1 |
| Haapalinna, A; Koivisto, A; Kuokkanen, K; Lehtimäki, J; Lehtimäki, T; Leino, T; Viitamaa, T; Virtanen, R | 1 |
| Chang, KC; Cho, MS; Chung, YK; Jeong, YS; Kim, HJ; Park, CS; Shin, MK; Sohn, JT | 1 |
| Altun, A; Aydin, C; Bagcivan, I; Gursoy, S; Koyuncu, A; Topcu, O | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
| Crecelius, AR; Dinenno, FA; Kirby, BS; Voyles, WF | 1 |
| Chang, KC; Jeong, YS; Kim, HJ; Kim, JG; Kwon, SC; Lee, SM; Ok, SH; Sohn, JT; Sung, HJ | 1 |
| Engström, M; Haapalinna, A; Höglund, I; Lehtimäki, J; Sallinen, J; Savola, JM; Sirviö, J; Virtanen, R; Wurster, S | 1 |
| Boyle, WA; Hamasaki, J; Hidaka, T; Kanmura, Y; Katai, R; Tsuneyoshi, I | 1 |
1 trial(s) available for dexmedetomidine and Muscle Contraction
| Article | Year |
|---|---|
Impaired modulation of postjunctional α
Topics: Adenosine Triphosphate; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Case-Control Studies; Dexmedetomidine; Female; Forearm; Humans; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Postmenopause; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction; Young Adult | 2018 |
20 other study(ies) available for dexmedetomidine and Muscle Contraction
| Article | Year |
|---|---|
Effects of dexmedetomidine on porcine pulmonary artery vascular smooth muscle.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Calcium; Calcium Channels; Dexmedetomidine; Muscle Contraction; Muscle, Smooth, Vascular; Pulmonary Artery; Swine | 2019 |
Sedation with midazolam worsens the diaphragm function than dexmedetomidine and propofol during mechanical ventilation in rats.
Topics: Anesthesia; Animals; Antioxidants; Autophagy; Biomechanical Phenomena; Cell Line; Dexmedetomidine; Diaphragm; Male; Midazolam; Muscle Contraction; Oxidants; Oxidative Stress; Propofol; Proteasome Endopeptidase Complex; Proteolysis; Rats, Wistar; Respiration, Artificial; Vital Signs | 2020 |
Anesthetic agents affect urodynamic parameters and anesthetic depth at doses necessary to facilitate preclinical testing in felines.
Topics: Anesthesia Recovery Period; Anesthetics; Animals; Cats; Chloralose; Dexmedetomidine; Dose-Response Relationship, Drug; GABA-A Receptor Agonists; Heart Rate; Isoflurane; Male; Models, Animal; Muscle Contraction; Muscle, Smooth; Pregnanediones; Pressure; Propofol; Urinary Bladder; Urodynamics | 2020 |
Dexmedetomidine's inhibitory effects on acetylcholine release from cholinergic nerves in guinea pig trachea: a mechanism that accounts for its clinical benefit during airway irritation.
Topics: Acetylcholine; Anesthetics; Animals; Cholinergic Neurons; Dexmedetomidine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Lidocaine; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Remifentanil; Trachea | 2017 |
Bidirectional Regulatory Effects of Dexmedetomidine on Porcine Coronary Tone In Vitro.
Topics: Animals; Blood Flow Velocity; Coronary Vessels; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Male; Models, Animal; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Swine | 2017 |
Dual effects of α2 -adrenoceptors in modulating myogenic tone in sheep isolated internal anal sphincter.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Anal Canal; Animals; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Muscle Contraction; Prazosin; Quinoxalines; Radioligand Assay; Receptors, Adrenergic, alpha; Sheep; Tissue Culture Techniques | 2014 |
α1- and α2-adrenergic responsiveness in human skeletal muscle feed arteries: the role of TRPV ion channels in heat-induced sympatholysis.
Topics: Acetylcholine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Arteries; Dexmedetomidine; Female; Hot Temperature; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitroprusside; Phenylephrine; Potassium Chloride; Ruthenium Red; Sulfonamides; Sympatholytics; TRPV Cation Channels; Vasoconstriction | 2014 |
Dexmedetomidine-induced contraction involves c-Jun NH2 -terminal kinase phosphorylation through activation of the 5-lipoxygenase pathway in the isolated endothelium-denuded rat aorta.
Topics: Animals; Aorta, Thoracic; Arachidonate 5-Lipoxygenase; Benzoquinones; Cyclooxygenase 2 Inhibitors; Dexmedetomidine; Endothelium, Vascular; JNK Mitogen-Activated Protein Kinases; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitrobenzenes; Phosphorylation; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Vasoconstriction | 2014 |
Dexmedetomidine-induced contraction involves phosphorylation of caldesmon by JNK in endothelium-denuded rat aortas.
Topics: Analysis of Variance; Animals; Anthracenes; Aorta; Benzophenanthridines; Blotting, Western; Calmodulin-Binding Proteins; Cells, Cultured; Dexmedetomidine; Dose-Response Relationship, Drug; Muscle Contraction; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Rats; Receptors, Adrenergic, alpha-2; Signal Transduction; Yohimbine | 2014 |
Dexmedetomidine-Induced Contraction in the Isolated Endothelium-Denuded Rat Aorta Involves PKC-δ-mediated JNK Phosphorylation.
Topics: Animals; Aorta; Azepines; Benzophenanthridines; Carbazoles; Dexmedetomidine; Endothelium, Vascular; Indoles; Male; Maleimides; MAP Kinase Kinase 4; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Organ Culture Techniques; Phosphorylation; Protein Kinase C-delta; Rats, Sprague-Dawley; Vasoconstriction | 2015 |
Dexmedetomidine-Induced Contraction Involves CPI-17 Phosphorylation in Isolated Rat Aortas.
Topics: Adrenergic alpha-2 Receptor Agonists; Amides; Animals; Aorta; Benzophenanthridines; Calcium; Cells, Cultured; Dexmedetomidine; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle Proteins; Muscle, Smooth, Vascular; Myosin Light Chains; Phosphoproteins; Phosphorylation; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Yohimbine | 2016 |
Dexmedetomidine Inhibits Phenylephrine-induced Contractions via Alpha-1 Adrenoceptor Blockade and Nitric Oxide Release in Isolated Rat Aortae.
Topics: Adrenergic Agonists; Animals; Aorta; Dexmedetomidine; In Vitro Techniques; Male; Muscle Contraction; Nitric Oxide; Phenoxybenzamine; Phenylephrine; Rats; Receptors, Adrenergic; Serotonin | 2017 |
In vitro and in vivo profiling of fadolmidine, a novel potent alpha(2)-adrenoceptor agonist with local mode of action.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Blood-Brain Barrier; Cell Line; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Dexmedetomidine; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Imidazoles; Indans; Male; Mice; Muscle Contraction; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Transfection; Vas Deferens | 2008 |
Direct effect of dexmedetomidine on rat isolated aorta involves endothelial nitric oxide synthesis and activation of the lipoxygenase pathway.
Topics: Animals; Aorta; Cells, Cultured; Dexmedetomidine; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme Activation; Humans; Hypnotics and Sedatives; Lipoxygenase; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction | 2009 |
Altered spontaneous contractions of the ileum by anesthetic agents in rats exposed to peritonitis.
Topics: Anesthetics, Intravenous; Animals; Dexmedetomidine; Gastrointestinal Motility; Ileum; Male; Midazolam; Muscle Contraction; Muscle, Smooth; Peritonitis; Propofol; Rats; Rats, Wistar | 2009 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |
Modulation of postjunctional α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Aged; Aging; Dexmedetomidine; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Ultrasonography, Doppler; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Young Adult | 2011 |
c-Jun NH₂-terminal kinase contributes to dexmedetomidine-induced contraction in isolated rat aortic smooth muscle.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Anthracenes; Aorta; Dexmedetomidine; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Male; Muscle Contraction; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Protein Isoforms; Pyridines; Rats; Rats, Sprague-Dawley | 2011 |
Pharmacological characterization and CNS effects of a novel highly selective alpha2C-adrenoceptor antagonist JP-1302.
Topics: Acridines; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Binding, Competitive; Cell Membrane; Central Nervous System; Dexmedetomidine; Dose-Response Relationship, Drug; Electric Stimulation; Humans; Hypothermia; In Vitro Techniques; Male; Mice; Motor Activity; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Reflex, Startle; Swimming; Vas Deferens | 2007 |
Dual alpha(2)-adrenergic agonist and alpha(1)-adrenergic antagonist actions of dexmedetomidine on human isolated endothelium-denuded gastroepiploic arteries.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adult; Aged; Arteries; Clonidine; Dexmedetomidine; Drug Interactions; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Potassium; Regional Blood Flow; Stomach | 2002 |