dexmedetomidine has been researched along with Ischemia in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 12 (44.44) | 24.3611 |
| 2020's | 14 (51.85) | 2.80 |
| Authors | Studies |
|---|---|
| Du, H; Jia, L; Lyu, J; Sheng, M; Yu, H; Yu, W | 1 |
| Chen, QH; Hu, Q; Huang, YL; Liu, XM; Liu, ZR; Liu, ZY; Wang, WX; Zhang, HG; Zhang, Q; Zhang, XK | 1 |
| Jiang, Z; Liu, A; Peng, Y; She, C; Xu, Y; Zhu, J | 1 |
| Li, G; Liu, B; Wei, J; Zhou, J | 1 |
| Gao, H; Liu, Y; Wang, S; Yin, Y; Yu, J; Zhong, Y | 1 |
| Chen, S; Cheng, H; Wang, J; Wu, J; Yang, X | 1 |
| Chen, F; Han, X; He, Y; Hou, M; Leng, Y; Shi, Y; Tan, Z; Xu, Y | 1 |
| He, H; Li, P; Liu, P | 1 |
| Cheng, W; Liu, P; Liu, X; Wang, M; Wang, X; Zhao, S | 1 |
| Hopster, K; Kästner, SBR; König, KS; Neudeck, S; Pfarrer, C; Rohn, K; Verhaar, N | 1 |
| Chai, X; Gao, J; Geng, Q; Hu, Y; Jiang, J; Liang, X; Shi, S; Tang, C; Wang, J | 1 |
| Chen, Y; Huang, Y; Luo, H; Song, X; Xiong, B | 1 |
| Gao, Q; Li, C; Wu, Z; Xu, Y; Xue, H; Zhang, Y; Zhao, P | 1 |
| Cahilog, Z; Cao, J; Chen, Q; Chen, X; Chen, Y; Gu, J; Hu, L; Lu, K; Lu, S; Ning, J; Yi, B | 1 |
| Ainiwaer, Y; Geng, Q; He, B; Li, X; Lin, L; Zhang, B; Zhang, J | 1 |
| Duan, L; Liu, Z; Wang, GM; Wang, SL; Wang, Y; Xia, B | 1 |
| Pang, Q; Wang, Z; Zhou, W; Zhou, X; Zhou, Y | 1 |
| Li, GW; Ou, SS; Xiao, XY; Zhou, JH; Zhou, WY; Zhu, YX | 1 |
| Chen, Y; Dai, JC; Du, J; Fan, X; Li, JM; Wang, MH; Yang, B; Zhang, C; Zhou, J | 1 |
| Arslan, M; Cavunt-Bayraktar, A; Comu, FM; Kavutcu, M; Kucuk, A; Tosun, M; Yaylak, F | 1 |
| Dong, J; Tang, J; Yang, L; Zheng, J | 1 |
| Chen, H; Liu, L; Liu, X; Wang, H; Wang, L; Wang, M | 1 |
| Atasoy, P; Batislam, E; Gencay, IY; Kisa, U; Tuglu, D; Yilmaz, E; Yuvanc, E | 1 |
| Meng, FM; Xue, FS; Zhang, JQ; Zhang, W | 1 |
| Buyukbas, S; Cosar, M; Eser, O; Fidan, H; Mollaoglu, H; Sahin, O; Songur, A; Yaman, M | 1 |
| Bektaş, S; Can, M; Erol, B; Hanci, V; Mungan, G; Ozkoçak Turan, I; Tokgöz, H; Yurtlu, S | 1 |
| Akcay, F; Calik, M; Cetin, N; Gundogdu, C; Ingec, M; Isaoglu, U; Kurt, A; Polat, B; Suleyman, H; Yilmaz, M | 1 |
1 review(s) available for dexmedetomidine and Ischemia
| Article | Year |
|---|---|
Dexmedetomidine against intestinal ischemia/reperfusion injury: A systematic review and meta-analysis of preclinical studies.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Inflammation; Ischemia; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2023 |
2 trial(s) available for dexmedetomidine and Ischemia
| Article | Year |
|---|---|
Dexmedetomidine pretreatment attenuates myocardial ischemia reperfusion induced acute kidney injury and endoplasmic reticulum stress in human and rat.
Topics: Acute Kidney Injury; Aged; Animals; Apoptosis; China; Dexmedetomidine; Endoplasmic Reticulum Stress; Female; Humans; Ischemia; Kidney; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2020 |
Effects of dexmedetomidine on the function of distal organs and oxidative stress after lower limb ischaemia-reperfusion in elderly patients undergoing unilateral knee arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Knee; Dexmedetomidine; Humans; Ischemia; Oxidative Stress; Reperfusion; Reperfusion Injury | 2021 |
24 other study(ies) available for dexmedetomidine and Ischemia
| Article | Year |
|---|---|
Dexmedetomidine Ameliorates Hippocampus Injury and Cognitive Dysfunction Induced by Hepatic Ischemia/Reperfusion by Activating SIRT3-Mediated Mitophagy and Inhibiting Activation of the NLRP3 Inflammasome in Young Rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Cognitive Dysfunction; Dexmedetomidine; Hippocampus; Inflammasomes; Ischemia; Liver; Liver Diseases; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirtuins | 2020 |
Dexmedetomidine inhibits mitochondria damage and apoptosis of enteric glial cells in experimental intestinal ischemia/reperfusion injury via SIRT3-dependent PINK1/HDAC3/p53 pathway.
Topics: Animals; Apoptosis; Dexmedetomidine; Ischemia; Mitochondria; Neuroglia; Protein Kinases; Rats; Reperfusion Injury; Sirtuin 3; Tumor Suppressor Protein p53 | 2021 |
Dexmedetomidine Inhibits NF-κB-Transcriptional Activity in Neurons Undergoing Ischemia-Reperfusion by Regulating O-GlcNAcylation of SNW1.
Topics: Animals; Dexmedetomidine; Humans; Ischemia; Neuroblastoma; Neurons; NF-kappa B; Nuclear Receptor Coactivators; Rats; Reperfusion | 2022 |
Dexmedetomidine Ameliorated Cognitive Dysfunction Induced by Intestinal Ischemia Reperfusion in Mice with Possible Relation to the Anti-inflammatory Effect Through the Locus Coeruleus Norepinephrine System.
Topics: Adrenergic Antagonists; Animals; Anti-Inflammatory Agents; Benzylamines; Cognitive Dysfunction; Dexmedetomidine; Eosine Yellowish-(YS); Hematoxylin; Ischemia; Locus Coeruleus; Malondialdehyde; Mice; Neuroprotective Agents; Neurotoxins; Norepinephrine; Reperfusion; Reperfusion Injury; Tumor Necrosis Factor-alpha; Tyrosine 3-Monooxygenase; Yohimbine | 2022 |
Dexmedetomidine suppresses hippocampal astrocyte pyroptosis in cerebral hypoxic-ischemic neonatal rats by upregulating microRNA-148a-3p to inactivate the STAT/JMJD3 axis.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspase 1; Dexmedetomidine; Glucose; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Inflammation; Ischemia; MicroRNAs; Pyroptosis; Rats | 2023 |
DEXMEDETOMIDINE AMELIORATES ACUTE BRAIN INJURY INDUCED BY MYOCARDIAL ISCHEMIA-REPERFUSION VIA UPREGULATING THE HIF-1 PATHWAY.
Topics: Animals; Brain Injuries; Coronary Artery Disease; Dexmedetomidine; Humans; Ischemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Reperfusion Injury; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2023 |
Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Dexmedetomidine; Inflammation; Ischemia; Mice; Myocardial Ischemia; Myocardial Reperfusion Injury; Reperfusion Injury; Signal Transduction; Sirtuin 3 | 2023 |
Protective Effects of Dexmedetomidine and Oxycodone in Patients Undergoing Limb Ischemia-Reperfusion.
Topics: Adult; Aged; Brain-Derived Neurotrophic Factor; China; Dexmedetomidine; Endothelin-1; Fatty Acid Binding Protein 3; Female; Hemodynamics; Humans; Interleukin-6; Ischemia; Lower Extremity; Male; Malondialdehyde; Middle Aged; Oxycodone; Peripheral Vascular Diseases; Prospective Studies; Random Allocation; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2019 |
Ischaemic preconditioning and pharmacological preconditioning with dexmedetomidine in an equine model of small intestinal ischaemia-reperfusion.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Horses; Ischemia; Ischemic Preconditioning; Jejunum; Random Allocation; Reperfusion Injury | 2020 |
Dexmedetomidine ameliorates renal ischemia reperfusion-mediated activation of the NLRP3 inflammasome in alveolar macrophages.
Topics: Acute Kidney Injury; Acute Lung Injury; Adrenergic alpha-2 Receptor Agonists; AMP-Activated Protein Kinases; Animals; Cell Line; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Ischemia; Macrophages, Alveolar; NADPH Oxidase 4; Nitric Oxide Synthase Type III; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Real-Time Polymerase Chain Reaction; Reperfusion Injury; RNA, Messenger | 2020 |
Dexmedetomidine post-conditioning ameliorates long-term neurological outcomes after neonatal hypoxic ischemia: The role of autophagy.
Topics: Animals; Animals, Newborn; Autophagy; Brain; Cell Death; Dexmedetomidine; Female; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Ischemia; Ischemic Postconditioning; Male; Microglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2021 |
Dexmedetomidine Attenuates Myocardial Injury Induced by Renal Ischemia/Reperfusion by Inhibiting the HMGB1-TLR4-MyD88-NF-κB Signaling Pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; HMGB1 Protein; Ischemia; Male; Myeloid Differentiation Factor 88; Myocardial Infarction; NF-kappa B; Rats; Rats, Wistar; Reperfusion Injury; Toll-Like Receptor 4 | 2021 |
Dexmedetomidine preconditioning plays a neuroprotective role and suppresses TLR4/NF-κB pathways model of cerebral ischemia reperfusion.
Topics: Animals; Brain Ischemia; Dexmedetomidine; Infarction, Middle Cerebral Artery; Interferon-beta; Ischemia; Male; Neuroprotection; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
The protective effect of dexmedetomidine in a rat ex vivo lung model of ischemia-reperfusion injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blotting, Western; CCAAT-Enhancer-Binding Proteins; Dexmedetomidine; Disease Models, Animal; Heat-Shock Proteins; Ischemia; Lung; Male; Malondialdehyde; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reference Values; Reperfusion Injury; Reproducibility of Results; Superoxide Dismutase; Time Factors; Treatment Outcome | 2018 |
Dexmedetomidine protects liver cell line L-02 from oxygen-glucose deprivation-induced injury by down-regulation of microRNA-711.
Topics: Apoptosis; Cell Hypoxia; Cell Line; Cytokines; Cytoprotection; Dexmedetomidine; Down-Regulation; Glucose; Humans; Ischemia; Janus Kinase 1; Liver; Liver Diseases; MicroRNAs; Oxygen; p38 Mitogen-Activated Protein Kinases; Signal Transduction; STAT3 Transcription Factor | 2018 |
Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion.
Topics: Alanine Transaminase; Animals; Antibodies, Neutralizing; Aspartate Aminotransferases; Dexmedetomidine; Fibronectins; Intestines; Ischemia; Liver; Male; Malondialdehyde; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2019 |
The protective effects of dexmedetomidine on hepatic ischemia reperfusion injury.
Topics: Animals; Dexmedetomidine; Ischemia; Ischemic Preconditioning; Liver; Liver Diseases; Protective Agents; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury | 2014 |
Dexmedetomidine alleviates rat post-ischemia induced allodynia through GRK2 upregulation in superior cervical ganglia.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Disease Models, Animal; Forelimb; Functional Laterality; G-Protein-Coupled Receptor Kinase 2; Gene Expression Regulation; Hyperalgesia; Hypnotics and Sedatives; Ischemia; Neurons; Pain Threshold; Rats; Reperfusion Injury; Statistics, Nonparametric; Superior Cervical Ganglion; Time Factors | 2015 |
Acute hyperglycemia prevents dexmedetomidine-induced preconditioning against renal ischemia-reperfusion injury.
Topics: Acute Disease; Animals; Apoptosis; Blood Glucose; Creatinine; Dexmedetomidine; Hyperglycemia; Ischemia; Ischemic Preconditioning; Kidney; Kidney Tubules; Male; Models, Animal; Nephrectomy; Proto-Oncogene Proteins c-akt; Random Allocation; Rats, Sprague-Dawley; Reperfusion Injury; Urea | 2014 |
The antioxidant effect of dexmedetomidine on testicular ischemia-reperfusion injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antioxidants; Dexmedetomidine; Immunohistochemistry; Ischemia; Male; Oxidative Stress; Prospective Studies; Random Allocation; Rats, Wistar; Reference Values; Reperfusion Injury; Severity of Illness Index; Spermatic Cord Torsion; Testis; Time Factors | 2015 |
Dexmedetomidine protects against lung ischemia-reperfusion injury by the PI3K/Akt/HIF-1α signaling pathway.
Topics: Animals; Chromones; Dexmedetomidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypnotics and Sedatives; Hypoxia-Inducible Factor 1, alpha Subunit; Ischemia; Lung Injury; Male; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2016 |
The influence of dexmedetomidine on ischemic rat hippocampus.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Catalase; Cytokines; Dexmedetomidine; Disease Models, Animal; Hippocampus; In Situ Nick-End Labeling; Ischemia; Male; Malondialdehyde; Neurons; Nitric Oxide; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2008 |
Effect of dexmedetomidine on testicular torsion/detorsion damage in rats.
Topics: Animals; Antioxidants; Apoptosis; Apoptotic Protease-Activating Factor 1; Dexmedetomidine; Germ Cells; Ischemia; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Testis | 2010 |
An investigation about the inhibition of acute ischemia/reperfusion damage by dexmedetomidine in rat ovarian tissue.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Biomarkers; Dexmedetomidine; DNA Damage; Female; Glutathione; Guanine; Ischemia; Lipid Peroxidation; Malondialdehyde; Ovary; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Yohimbine | 2013 |