dexmedetomidine has been researched along with Infarction, Middle Cerebral Artery in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 11 (47.83) | 24.3611 |
| 2020's | 10 (43.48) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, S; Li, G; Liu, Q; Wu, J | 1 |
| Chen, L; Dong, S; Duan, F; Hu, M; Huang, J; Men, Y; Zhang, Y | 1 |
| Ding, C; Han, GJ; Ma, SS; Min, XZ; Wang, XQ | 1 |
| He, J; Li, J; Liu, H; Liu, M; Wang, K; Zhang, H | 1 |
| Li, S; Liu, J; Wen, Q; Xie, K; Yu, J; Yu, L; Zhu, Y | 1 |
| Li, P; Liu, H; Zhang, Y | 1 |
| Du, H; Guo, H; Hu, Z; Liu, W; Lv, J; Wang, L; Zhang, Y | 1 |
| Li, Z; Luo, X; Sun, K; Wu, K; Xie, W; Yang, Q; Zhang, J; Zhang, X; Zhu, J | 1 |
| Hao, S; Ling, Y; Liu, J; Yu, S; Zhao, Q | 1 |
| Liu, Y; Ma, X; Zhang, W; Zhao, H; Zhu, Y | 1 |
| Dong, H; Jiang, J; Jiao, Y; Shao, J; Tang, D; Wang, Z; Xu, S; Yin, W; Yu, W; Zhang, Y; Zhou, W | 1 |
| Liu, W; Shao, C; Sun, J; Wang, Y; Xu, M; Zang, C | 1 |
| Duan, L; Liu, Z; Wang, GM; Wang, SL; Wang, Y; Xia, B | 1 |
| Dong, H; He, Z; Ma, X; Wang, Z; Zhou, W | 1 |
| Fang, T; Fu, Q; Liu, C; Mu, R; Tian, F; Wang, F; Yu, B; Zhang, L; Zhang, Y; Zhou, C | 1 |
| Chen, W; Teng, L; Yin, C; Zhang, H; Zhao, Q | 1 |
| Cao, D; Cao, J; Chen, L; Cong, H; Wang, M; Xiang, H; Yang, Y; Ying, T | 1 |
| Barsoum, S; Chi, OZ; Dinani, A; Grayson, J; Liu, X; Weiss, HR | 1 |
| Du, H; He, Y; Kou, D; Li, Z; Wang, Z; Yu, W | 1 |
| Nakano, T; Okamoto, H | 1 |
| Kaku, Y; Kanou, K; Kokuzawa, J; Tsujimoto, M; Yamashita, K | 1 |
| Chen, L; Ma, LL; Qian, LB; Wang, CC; Wen, CY; Yan, M; Yu, J; Yu, LN; Zhu, MH; Zhu, YM | 1 |
| Haapalinna, A; Kuhmonen, J; Sivenius, J | 1 |
23 other study(ies) available for dexmedetomidine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
MiR-665 Participates in the Protective Effect of Dexmedetomidine in Ischemic Stroke by ROCK2/NF-κB Axis.
Topics: Animals; Apoptosis; Brain Ischemia; Cytokines; Dexmedetomidine; Glucose; Infarction, Middle Cerebral Artery; Ischemic Stroke; Mice; MicroRNAs; NF-kappa B; Oxygen; Reperfusion Injury; rho-Associated Kinases; Up-Regulation | 2022 |
Dexmedetomidine exerts its protective effect on cerebral ischemia reperfusion injury in mice by inhibiting ferroptosis.
Topics: Animals; Brain Ischemia; Dexmedetomidine; Disease Models, Animal; Ferroptosis; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Reperfusion Injury | 2022 |
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Brain Ischemia; Dexmedetomidine; Hippocampus; Infarction, Middle Cerebral Artery; Kelch-Like ECH-Associated Protein 1; Mitophagy; NF-E2-Related Factor 2; Rats; Reperfusion Injury; Signal Transduction | 2022 |
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury via inhibiting autophagy through PI3K/Akt/mTOR pathway.
Topics: Animals; Autophagy; Beclin-1; Cerebral Infarction; Dexmedetomidine; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; TOR Serine-Threonine Kinases | 2023 |
Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats.
Topics: Animals; Autophagy; Brain Injuries; Dexmedetomidine; Infarction, Middle Cerebral Artery; Inflammation; JNK Mitogen-Activated Protein Kinases; Learning Disabilities; MAP Kinase Signaling System; Memory Disorders; Rats; Reperfusion Injury | 2019 |
The role of Wnt/β-catenin pathway in the protection process by dexmedetomidine against cerebral ischemia/reperfusion injury in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; beta Catenin; Dexmedetomidine; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Wnt Proteins | 2019 |
Dexmedetomidine had neuroprotective effects on hippocampal neuronal cells via targeting lncRNA SHNG16 mediated microRNA-10b-5p/BDNF axis.
Topics: 3' Untranslated Regions; Animals; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cell Hypoxia; Cell Line; Cell Survival; Dexmedetomidine; Down-Regulation; Gene Expression Regulation; Hippocampus; Infarction, Middle Cerebral Artery; Mice; MicroRNAs; Neurons; Neuroprotection; Neuroprotective Agents; Rats; RNA, Long Noncoding; Signal Transduction; Up-Regulation | 2020 |
Dexmedetomidine exerts a protective effect on ischemic brain injury by inhibiting the P2X7R/NLRP3/Caspase-1 signaling pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brain Chemistry; Brain Edema; Brain Ischemia; Caspase 1; Dexmedetomidine; Infarction, Middle Cerebral Artery; Male; Microglia; Neuroprotective Agents; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats, Sprague-Dawley; Receptors, Purinergic P2X7; Signal Transduction | 2021 |
The Protective Effects of Dexmedetomidine against Hypoxia/Reoxygenation-Induced Inflammatory Injury and Permeability in Brain Endothelial Cells Mediated by Sigma-1 Receptor.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Dexmedetomidine; Endothelial Cells; Hypoxia; Infarction, Middle Cerebral Artery; Mice; Permeability; Receptors, sigma; Reperfusion Injury; Sigma-1 Receptor | 2021 |
Dexmedetomidine attenuates neuronal injury induced by cerebral ischemia‑reperfusion by regulating miR‑199a.
Topics: Animals; Antigens, Nuclear; Beclin-1; Brain Ischemia; Caspase 3; Cerebral Cortex; Dexmedetomidine; Disease Models, Animal; Infarction, Middle Cerebral Artery; Injections; Male; MicroRNAs; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; RNA-Binding Proteins | 2021 |
Dexmedetomidine maintains blood-brain barrier integrity by inhibiting Drp1-related endothelial mitochondrial dysfunction in ischemic stroke.
Topics: Adenylate Kinase; Adrenergic alpha-2 Receptor Antagonists; Animals; Blood-Brain Barrier; Cell Line; Cytokines; Dexmedetomidine; Disease Models, Animal; Dynamins; Endothelial Cells; Glial Fibrillary Acidic Protein; Humans; Indole Alkaloids; Infarction, Middle Cerebral Artery; Ischemic Stroke; Male; Mitochondria; Mitochondrial Dynamics; Neuroprotective Agents; Phosphorylation; Rats, Sprague-Dawley; Zonula Occludens-1 Protein | 2021 |
Protective effects of dexmedetomidine on cerebral ischemia/reperfusion injury via the microRNA-214/ROCK1/NF-κB axis.
Topics: Animals; Apoptosis; Brain Ischemia; Dexmedetomidine; Disease Models, Animal; Hippocampus; Infarction, Middle Cerebral Artery; Male; MicroRNAs; Neuroprotective Agents; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; rho-Associated Kinases | 2021 |
Dexmedetomidine preconditioning plays a neuroprotective role and suppresses TLR4/NF-κB pathways model of cerebral ischemia reperfusion.
Topics: Animals; Brain Ischemia; Dexmedetomidine; Infarction, Middle Cerebral Artery; Interferon-beta; Ischemia; Male; Neuroprotection; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Dexmedetomidine pretreatment inhibits cerebral ischemia/reperfusion‑induced neuroinflammation via activation of AMPK.
Topics: Adenylate Kinase; Animals; Apoptosis; Brain Ischemia; Cerebral Cortex; Dexmedetomidine; Enzyme Activation; Infarction, Middle Cerebral Artery; Inflammation; Male; Motor Activity; Neurons; Phosphorylation; Rats, Sprague-Dawley; Reperfusion Injury | 2018 |
Dexmedetomidine alleviates cerebral ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress dependent apoptosis through the PERK-CHOP-Caspase-11 pathway.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Caspases; Dexmedetomidine; Disease Models, Animal; eIF-2 Kinase; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucose; Heat-Shock Proteins; Infarction, Middle Cerebral Artery; Male; Neurons; Neuroprotection; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Transcription Factor CHOP | 2018 |
Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats via Extracellular Signal-Regulated Kinase/Cyclic Adenosine Monophosphate Response Element Binding Protein Signaling Pathway.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Death; Dexmedetomidine; Extracellular Signal-Regulated MAP Kinases; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2019 |
Protective effect of dexmedetomidine against diabetic hyperglycemia-exacerbated cerebral ischemia/reperfusion injury: An in vivo and in vitro study.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Dexmedetomidine; Diabetes Mellitus, Experimental; Disease Models, Animal; Hyperglycemia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction | 2019 |
Effects of dexmedetomidine on microregional O2 balance during reperfusion after focal cerebral ischemia.
Topics: Adrenergic alpha-Agonists; Animals; Blood Gas Analysis; Brain Ischemia; Cerebrovascular Circulation; Dexmedetomidine; Hemodynamics; Infarction, Middle Cerebral Artery; Male; Oxygen Consumption; Pons; Rats; Rats, Inbred F344; Reperfusion Injury | 2015 |
Effects of propofol-dexmedetomidine combination on ischemia reperfusion-induced cerebral injury.
Topics: Animals; Dexmedetomidine; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Male; Propofol; Rats; Rats, Sprague-Dawley | 2014 |
Dexmedetomidine-induced cerebral hypoperfusion exacerbates ischemic brain injury in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Dexmedetomidine; Hypnotics and Sedatives; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vascular Resistance; Yohimbine | 2009 |
Superficial temporal artery-middle cerebral artery bypass using local anesthesia and a sedative without endotracheal general anesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Endotracheal; Anesthesia, General; Anesthesia, Local; Carotid Artery, Internal; Carotid Stenosis; Cerebral Angiography; Cerebral Revascularization; Conscious Sedation; Dexmedetomidine; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Imaging, Three-Dimensional; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Magnetic Resonance Angiography; Male; Middle Aged; Minimally Invasive Surgical Procedures; Patient Satisfaction; Postoperative Complications; Prospective Studies; Stroke; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2012 |
Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Cell Death; Cerebral Cortex; Dexmedetomidine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neuroprotective Agents; Phosphatidylinositol 3-Kinase; Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2013 |
Effects of dexmedetomidine after transient and permanent occlusion of the middle cerebral artery in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Blood Glucose; Blood Pressure; Body Temperature; Brain; Dexmedetomidine; Hypoxia-Ischemia, Brain; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury | 2001 |