dexmedetomidine has been researched along with Heart Disease, Ischemic in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 9 (39.13) | 24.3611 |
| 2020's | 12 (52.17) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, S; Chen, H; Chen, Y; Xu, X; Yang, Z; Yin, C | 1 |
| Deng, X; Luo, W; Tu, S; Wang, X; Ye, F; Zeng, L; Zhang, Z | 1 |
| Jiang, L; Qian, J; Qian, X; Wang, L; Wang, Q; Wang, Z; Yang, Y; Yao, M; Zhao, Y | 1 |
| Cascino, A; Conti, S; Ferrara, G; Sabatino, F; Sgarito, G | 1 |
| Lu, SJ; Qi, QL; Wang, HY; Zhang, YJ | 1 |
| Chen, ZR; Hong, Y; Huang, WQ; Wen, SH; Zhan, YQ | 1 |
| He, H; Li, P; Liu, P | 1 |
| Chen, WR; Ji, FH; Liu, H; Liu, HY; Meng, XW; Peng, K; Xia, F; Xia, ZY; Zhang, J | 1 |
| Chai, X; Gao, J; Geng, Q; Hu, Y; Jiang, J; Liang, X; Shi, S; Tang, C; Wang, J | 1 |
| Davis, JRJ; Wu, ZL; Zhu, Y | 1 |
| Sun, Z; Wang, H; Xia, Y | 1 |
| Liang, R; Qian, J; Qu, Y; Song, N; Wang, Z; Xiong, W; Yang, Y; Zhou, R | 1 |
| Han, D; Shen, J; Sun, Y; Zhao, W; Zhu, K | 1 |
| Cheng, X; Gao, Q; Hu, J; Li, X; Li, Z; Wang, Y; Ye, H | 1 |
| Chen, Q; Chen, S; Jia, C; Jiang, H; Liu, X; Wang, D; Xu, Z; Zhang, D; Zhou, Z | 1 |
| Fleming, N; Ji, F; Li, Z; Liu, H; Nguyen, H; Shi, P; Young, N | 1 |
| Arslan, M; Elmas, C; Erer, D; Goktas, G; Iriz, E; Oktar, GL; Ozer, A; Tatar, T; Zor, MH | 1 |
| Alkan, M; Arslan, M; Bilge, M; Çelik, A; Erdem, Ö; Kavutçu, M; Kip, G; Kiraz, HA; Özer, A; Şıvgın, V | 1 |
| Cheng, XY; Gao, Q; Gu, XY; Li, XH; Zhang, Y; Zong, QF | 1 |
| Ji, FH; Meng, XW; Peng, K; Zhang, J; Zhang, JJ | 1 |
| Chalikonda, SA | 1 |
| Díaz-Araya, G; Duaso, J; Echevarria, G; Galvez, F; Garcia, L; Hassi, M; Humeres, C; Ibacache, M; Lavandero, S; Pedrozo, Z; Sanchez, G | 1 |
| Boussofara, M; Kaddour, C; Mtaallah, MH; Nefaa, MN | 1 |
2 review(s) available for dexmedetomidine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Alpha2-adrenergic agonists and their role in the prevention of perioperative adverse cardiac events.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Humans; Imidazoles; Myocardial Ischemia; Postoperative Complications | 2009 |
[Clonidine and anesthesia].
Topics: Adrenergic alpha-Agonists; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthetics, Local; Clonidine; Dexmedetomidine; Drug Interactions; Hemodynamics; Humans; Hypnotics and Sedatives; Imidazoles; Injections, Epidural; Injections, Spinal; Intraoperative Complications; Intubation, Intratracheal; Myocardial Ischemia; Preanesthetic Medication; Risk Factors; Sympatholytics; Time Factors | 2004 |
3 trial(s) available for dexmedetomidine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Dexmedetomidine pretreatment attenuates myocardial ischemia reperfusion induced acute kidney injury and endoplasmic reticulum stress in human and rat.
Topics: Acute Kidney Injury; Aged; Animals; Apoptosis; China; Dexmedetomidine; Endoplasmic Reticulum Stress; Female; Humans; Ischemia; Kidney; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2020 |
[Effects of dexmedetomidine on perioperative cardiac adverse events in elderly patients with
coronary heart disease].
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Biomarkers; Bradycardia; C-Reactive Protein; Coronary Disease; Dexmedetomidine; Humans; Incidence; Myocardial Ischemia; Natriuretic Peptide, Brain; Peptide Fragments; Postoperative Complications; Stomach Neoplasms; Tachycardia; Troponin I | 2017 |
Perioperative dexmedetomidine improves outcomes of cardiac surgery.
Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Aged; Cardiac Surgical Procedures; Catecholamines; Delirium; Dexmedetomidine; Female; Heart Diseases; Hospital Mortality; Hospital Records; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Myocardial Ischemia; Patient Readmission; Perioperative Care; Postoperative Complications; Respiration, Artificial; Retrospective Studies; Sepsis; Stroke; Treatment Outcome | 2013 |
18 other study(ies) available for dexmedetomidine and Heart Disease, Ischemic
| Article | Year |
|---|---|
Dexmedetomidine Preconditioning Reduces Myocardial Ischemia-Reperfusion Injury in Rats by Inhibiting the PERK Pathway.
Topics: Animals; Dexmedetomidine; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Reperfusion Injury; Signal Transduction | 2021 |
Dexmedetomidine Mitigates Myocardial Ischemia/Reperfusion-Induced Mitochondrial Apoptosis through Targeting lncRNA HCP5.
Topics: Apoptosis; Dexmedetomidine; Humans; MicroRNAs; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; RNA, Long Noncoding | 2022 |
Dexmedetomidine attenuates myocardial ischemia/reperfusion-induced ferroptosis via AMPK/GSK-3β/Nrf2 axis.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Dexmedetomidine; Ferroptosis; Glycogen Synthase Kinase 3 beta; Myocardial Ischemia; Myocardial Reperfusion Injury; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley | 2022 |
Dexmedetomidine for sedation during epicardial ablation for ventricular tachycardia: a single-center experience.
Topics: Aged; Bradycardia; Catheter Ablation; Dexmedetomidine; Epicardial Mapping; Female; Humans; Hypotension; Male; Middle Aged; Myocardial Ischemia; Myocarditis; Tachycardia, Ventricular; Treatment Outcome | 2023 |
Effects of electroacupuncture with dexmedetomidine on myocardial ischemia/reperfusion injury in rats.
Topics: Adenosine Triphosphate; Animals; Dexmedetomidine; Electroacupuncture; Male; Malondialdehyde; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase | 2022 |
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling.
Topics: Animals; Apoptosis; Creatine Kinase, MB Form; Dexmedetomidine; Disease Models, Animal; Hypoxia; Mice; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Receptors, Adrenergic, alpha; Reperfusion Injury; Signal Transduction | 2023 |
Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway.
Topics: AMP-Activated Protein Kinases; Animals; Apoptosis; Autophagy; Dexmedetomidine; Inflammation; Ischemia; Mice; Myocardial Ischemia; Myocardial Reperfusion Injury; Reperfusion Injury; Signal Transduction; Sirtuin 3 | 2023 |
Dexmedetomidine post-treatment attenuates cardiac ischaemia/reperfusion injury by inhibiting apoptosis through HIF-1α signalling.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Dexmedetomidine; Disease Models, Animal; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Protective Agents; Rats; Rats, Sprague-Dawley | 2020 |
Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cell Line; Cell Survival; Dexmedetomidine; Heart; Humans; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Oxidative Stress; Perfusion; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Thioredoxins | 2020 |
Dexmedetomidine: A potential therapy for myocardial ischemia/reperfusion injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Dexmedetomidine; Humans; Myocardial Ischemia; Myocardial Reperfusion Injury | 2021 |
Dexmedetomidine preconditioning mitigates myocardial ischemia/reperfusion injury via inhibition of mast cell degranulation.
Topics: Animals; Apoptosis; Arrhythmias, Cardiac; Cardiotonic Agents; Cell Degranulation; Cell Line; Cell Proliferation; Dexmedetomidine; Hemodynamics; Ischemic Preconditioning; Male; Mast Cells; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; p-Methoxy-N-methylphenethylamine; Rats; Rats, Sprague-Dawley | 2021 |
Effects of Dexmedetomidine Postconditioning on Myocardial Ischemia/Reperfusion Injury in Diabetic Rats: Role of the PI3K/Akt-Dependent Signaling Pathway.
Topics: Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Glycogen Synthase Kinase 3 beta; Heart; Ischemic Postconditioning; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Dexmedetomidine Attenuates Renal and Myocardial Ischemia/Reperfusion Injury in a Dose-Dependent Manner by Inhibiting Inflammatory Response.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Inflammation; Inflammation Mediators; Kidney Diseases; Male; Myocardial Ischemia; Rats; Rats, Wistar; Reperfusion Injury | 2019 |
The protective effects of dexmedetomidine on liver injury-induced myocardial ischemia reperfusion.
Topics: Animals; Coronary Vessels; Dexmedetomidine; Humans; Liver; Liver Diseases; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Protective Agents; Rats; Rats, Wistar | 2014 |
Dexmedetomidine protects from post-myocardial ischaemia reperfusion lung damage in diabetic rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Glutathione Transferase; Lung; Lung Injury; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Wistar | 2015 |
Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury.
Topics: Animals; bcl-2-Associated X Protein; Biomarkers; Cardiotonic Agents; Caspase 3; Creatine Kinase, MB Form; Dexmedetomidine; Disease Models, Animal; Glycogen Synthase Kinase 3 beta; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; RNA, Messenger; Signal Transduction; Superoxide Dismutase | 2016 |
Dexmedetomidine preconditioning may attenuate myocardial ischemia/reperfusion injury by down-regulating the HMGB1-TLR4-MyD88-NF-кB signaling pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Down-Regulation; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Male; Myeloid Differentiation Factor 88; Myocardial Ischemia; Myocardial Reperfusion Injury; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4 | 2017 |
Dexmedetomidine preconditioning activates pro-survival kinases and attenuates regional ischemia/reperfusion injury in rat heart.
Topics: Animals; Dexmedetomidine; Male; Myocardial Ischemia; Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2012 |