Page last updated: 2024-08-24

dexmedetomidine and Endotoxin Shock

dexmedetomidine has been researched along with Endotoxin Shock in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (13.33)29.6817
2010's16 (53.33)24.3611
2020's10 (33.33)2.80

Authors

AuthorsStudies
Auler-Jr, JOC; Carnicelli, P; Fantoni, DT; Ida, KK; Kahvegian, MAP; Monteiro Filho, A; Otsuki, DA; Rouby, JJ1
He, C; Huang, X1
Du, K; Xu, Y; Zhang, W1
Ertmer, C; Morelli, A; Rehberg, SW; Sanfilippo, F1
Chen, M; Gong, F; Hong, J; Hu, B; Jiang, L; Liu, J; Mo, S; Shi, K; Sun, R; Tu, Y; Xu, L; Yang, X; Zheng, Y1
Leone, M; Meresse, Z1
Bosso, S; Brazzi, L; Montrucchio, G; Sales, G; Scanu, M1
Dargent, A; Fournel, I; Jacquier, M; Quenot, JP; Quintin, L1
Bailey, M; Bellomo, R; Cioccari, L; Eastwood, GM; Howe, B; Jakob, SM; Luethi, N; Merz, TM; Messmer, AS; Peck, L; Proimos, HK; Shehabi, Y; Takala, J; Young, H1
Li, GC; Li, ZB; Qin, J1
Dargent, A; Quenot, JP; Quintin, L1
Ferreira, J1
Kato, S; Kawazoe, Y; Miyamoto, K; Morimoto, T; Nakashima, T; Ohta, Y; Shima, N; Ueda, K; Yamamura, H1
Hammond, DA; Nelson, KM; Patel, GP1
Arnemann, P; D'Egidio, A; Ertmer, C; Frati, G; Greco, E; Hessler, M; Kampmeier, TG; Morelli, A; Orecchioni, A; Rehberg, SW; Sanfilippo, F; Santonocito, C; Westphal, M1
Geloen, A; Ghignone, M; Leroy, S; Petitjeans, F; Pichot, C; Quintin, L1
Ertmer, C; Morelli, A; Rehberg, S; Sanfilippo, F2
Derry, KL; Hampton, SR; Park, JH1
Chapelier, K; Cividjian, A; Dantony, E; Geloen, A; May, CN; Quintin, L; Rabilloud, M1
Dünser, MW; Gradwohl-Matis, I1
Guo, F; Li, Q; Liu, L; Longhini, F; Qiu, H; Yang, Y; Yu, T1
Géloën, A; Ghignone, M; Julien, C; Leroy, S; May, CN; Pichot, C; Quintin, L1
Guo, F; Huang, HY; Tu, LY; Wang, Q; Yan, CY; Yu, X1
Achurra, P; Alegría, L; Bakker, J; Bruhn, A; Castro, R; Gomez, J; Hernández, G; Jarufe, N; Kattan, E; Luengo, C; Ospina-Tascón, G; Rebolledo, R; Soto, D; Tapia, P1
Bissell, BD; Ferreira, JA1
Inaba, H; Kobayashi, K; Kurita, A; Taniguchi, T; Yamamoto, K1
Kargi, M; Memiş, D; Sut, N1
Kanakura, H; Kidani, Y; Takemoto, Y; Taniguchi, T; Yamamoto, K1
Hinohara, H; Kadoi, Y; Kawauchi, C; Kunimoto, F; Saito, S1

Reviews

4 review(s) available for dexmedetomidine and Endotoxin Shock

ArticleYear
The efficacy of dexmedetomidine for septic shock: A meta-analysis of randomized controlled trials.
    Medicine, 2023, Sep-01, Volume: 102, Issue:35

    Topics: Control Groups; Databases, Factual; Dexmedetomidine; Humans; Randomized Controlled Trials as Topic; Shock, Septic

2023
The Theory is Out There: The Use of ALPHA-2 Agonists in Treatment of Septic Shock.
    Shock (Augusta, Ga.), 2018, Volume: 49, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Dexmedetomidine; Humans; Shock, Septic

2018
Pressor Response to Noradrenaline in the Setting of Septic Shock: Anything New under the Sun-Dexmedetomidine, Clonidine? A Minireview.
    BioMed research international, 2015, Volume: 2015

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Dexmedetomidine; Humans; Inflammation; Multiple Organ Failure; Norepinephrine; Rats; Sheep; Shock, Septic

2015
Misdirected Sympathy: The Role of Sympatholysis in Sepsis and Septic Shock.
    Journal of intensive care medicine, 2018, Volume: 33, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Catecholamines; Clonidine; Dexmedetomidine; Humans; Propanolamines; Sepsis; Shock, Septic; Stroke Volume; Sympathetic Nervous System; Sympatholytics; Tachycardia

2018

Trials

5 trial(s) available for dexmedetomidine and Endotoxin Shock

ArticleYear
The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial.
    Critical care (London, England), 2020, 07-16, Volume: 24, Issue:1

    Topics: Aged; Aged, 80 and over; Deep Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Respiration, Artificial; Retrospective Studies; Shock, Septic; Switzerland; Vasoconstrictor Agents; Victoria

2020
Effect of Dexmedetomidine on Lactate Clearance in Patients With Septic Shock: A Subanalysis of a Multicenter Randomized Controlled Trial.
    Shock (Augusta, Ga.), 2018, Volume: 50, Issue:2

    Topics: Aged; Aged, 80 and over; Dexmedetomidine; Female; Humans; Lactic Acid; Male; Middle Aged; Respiration, Artificial; Shock, Septic; Time Factors

2018
The Effect of Propofol and Dexmedetomidine Sedation on Norepinephrine Requirements in Septic Shock Patients: A Crossover Trial.
    Critical care medicine, 2019, Volume: 47, Issue:2

    Topics: Acid-Base Equilibrium; Adrenergic alpha-Agonists; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Middle Aged; Norepinephrine; Propofol; Shock, Septic

2019
[Clinical application of different sedation regimen in patients with septic shock].
    Zhonghua yi xue za zhi, 2016, Jun-14, Volume: 96, Issue:22

    Topics: Anesthesia; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Midazolam; Propofol; Respiration, Artificial; Shock, Septic; Time Factors; Treatment Outcome

2016
Comparative effects of propofol vs dexmedetomidine on cerebrovascular carbon dioxide reactivity in patients with septic shock.
    British journal of anaesthesia, 2008, Volume: 100, Issue:2

    Topics: Aged; Blood Flow Velocity; Carbon Dioxide; Cerebrovascular Circulation; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Middle Aged; Middle Cerebral Artery; Propofol; Prospective Studies; Respiration, Artificial; Shock, Septic; Ultrasonography, Doppler, Transcranial

2008

Other Studies

21 other study(ies) available for dexmedetomidine and Endotoxin Shock

ArticleYear
Effects of dexmedetomidine on hemodynamic, oxygenation, microcirculation, and inflammatory markers in a porcine model of sepsis.
    Acta cirurgica brasileira, 2022, Volume: 37, Issue:7

    Topics: Animals; Dexmedetomidine; Hemodynamics; Microcirculation; Oxygen; Sepsis; Shock, Septic; Swine

2022
Comparison of Propofol and Dexmedetomidine Sedation in Septic Shock.
    Critical care medicine, 2019, Volume: 47, Issue:12

    Topics: Conscious Sedation; Cross-Over Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Norepinephrine; Propofol; Shock, Septic

2019
The authors reply.
    Critical care medicine, 2019, Volume: 47, Issue:12

    Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic

2019
Dexmedetomidine protects against acute kidney injury in patients with septic shock.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Analgesics, Non-Narcotic; China; Cohort Studies; Dexmedetomidine; Female; Humans; Male; Middle Aged; Propofol; Respiration, Artificial; Shock, Septic

2020
Dexmedetomidine as a promise.
    Minerva anestesiologica, 2020, Volume: 86, Issue:8

    Topics: Dexmedetomidine; Humans; Hypnotics and Sedatives; Shock; Shock, Septic; Vasoconstrictor Agents

2020
Are other effects of dexmedetomidine playing a role in explaining norepinephrine requirements decrease in septic shock patients?
    Minerva anestesiologica, 2021, Volume: 87, Issue:1

    Topics: Dexmedetomidine; Humans; Hypnotics and Sedatives; Norepinephrine; Shock, Septic; Vasoconstrictor Agents

2021
Vasopressor for refractory septic shock: dexmedetomidine could help decrease norepinephrine requirements.
    Minerva anestesiologica, 2020, Volume: 86, Issue:8

    Topics: Dexmedetomidine; Humans; Norepinephrine; Shock; Shock, Septic; Vasoconstrictor Agents

2020
Dexmedetomidine Attenuates Lung Injury in Toxic Shock Rats by Inhibiting Inflammation and Autophagy.
    Archives of medical research, 2021, Volume: 52, Issue:3

    Topics: Animals; Autophagy; Dexmedetomidine; Disease Models, Animal; Hypnotics and Sedatives; Inflammation; Lung Injury; Male; Rats; Rats, Sprague-Dawley; Shock, Septic

2021
Septic shock, noradrenaline requirements and alpha-2 agonists: Fishing in the right pond?
    Critical care (London, England), 2021, 02-09, Volume: 25, Issue:1

    Topics: Critical Care; Dexmedetomidine; Humans; Norepinephrine; Ponds; Shock, Septic

2021
Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock.
    Journal of intensive care medicine, 2020, Volume: 35, Issue:9

    Topics: Adult; Aged; Bradycardia; Critical Care; Critical Care Outcomes; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Propofol; Retrospective Studies; Shock, Septic

2020
On the Right Track, Finally?
    Critical care medicine, 2019, Volume: 47, Issue:5

    Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic

2019
The authors reply.
    Critical care medicine, 2019, Volume: 47, Issue:5

    Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic

2019
Use of Dexmedetomidine for Deep Sedation and Reduction of Vasopressor Requirement?
    Critical care medicine, 2019, Volume: 47, Issue:8

    Topics: Conscious Sedation; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Norepinephrine; Propofol; Shock, Septic

2019
The authors reply.
    Critical care medicine, 2019, Volume: 47, Issue:8

    Topics: Cross-Over Studies; Dexmedetomidine; Humans; Norepinephrine; Propofol; Shock, Septic

2019
Clonidine and dexmedetomidine increase the pressor response to norepinephrine in experimental sepsis: a pilot study.
    Critical care medicine, 2013, Volume: 41, Issue:12

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Arterial Pressure; Clonidine; Dexmedetomidine; Hypotension; Lipopolysaccharides; Male; Norepinephrine; Pilot Projects; Random Allocation; Rats; Rats, Sprague-Dawley; Shock, Septic; Vasoconstrictor Agents

2013
α(2)-agonists to restore adrenergic vasoconstrictor responsiveness in septic shock: thinking outside of the box or fishing in the wrong pond?
    Critical care medicine, 2013, Volume: 41, Issue:12

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Arterial Pressure; Clonidine; Dexmedetomidine; Hypotension; Male; Shock, Septic

2013
Different effects of propofol and dexmedetomidine on preload dependency in endotoxemic shock with norepinephrine infusion.
    The Journal of surgical research, 2015, Volume: 198, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Dexmedetomidine; Endotoxemia; Heart Rate; Norepinephrine; Propofol; Rabbits; Shock, Septic; Systole

2015
Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock.
    Critical care (London, England), 2016, 08-02, Volume: 20, Issue:1

    Topics: Animals; Chile; Dexmedetomidine; Heart Rate; Hemodynamics; Hyperlactatemia; Lactic Acid; Models, Animal; Propanolamines; Sheep; Shock, Septic

2016
Dose- and time-related effects of dexmedetomidine on mortality and inflammatory responses to endotoxin-induced shock in rats.
    Journal of anesthesia, 2008, Volume: 22, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Blood Gas Analysis; Blood Pressure; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Inflammation; Interleukin-6; Male; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Survival Rate; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha

2008
Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LIMON to patients with early septic shock: a pilot study.
    Journal of critical care, 2009, Volume: 24, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Coloring Agents; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Indocyanine Green; Liver Circulation; Liver Function Tests; Male; Middle Aged; Pilot Projects; Propofol; Respiration, Artificial; Shock, Septic

2009
Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats.
    Critical care medicine, 2004, Volume: 32, Issue:6

    Topics: Animals; Dexmedetomidine; Endotoxins; Hemodynamics; Hypnotics and Sedatives; Inflammation; Interleukin-6; Lung; Male; Neutrophils; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Tumor Necrosis Factor-alpha

2004