dexmedetomidine has been researched along with Encephalopathy, Traumatic in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 15 (53.57) | 24.3611 |
| 2020's | 13 (46.43) | 2.80 |
| Authors | Studies |
|---|---|
| Cakir-Aktas, C; Karakaya, D; Mut, M; Soylemezoglu, F; Uzun, S | 1 |
| Anstey, J; Bellomo, R; Jeffcote, T; Mcnamara, R; Udy, A; Weir, T | 1 |
| Badulescu, AV; Burlacu, CC; Buzoianu, AD; Mitre, AO; Neag, MA; Sirbu, AC | 1 |
| Xiao, Q; Xu, J | 1 |
| Cox, CS; Haase, CM; Olson, SD; Scott, MC | 1 |
| Chen, W; Huang, H; Miao, H; Su, YY; Zhang, Y | 1 |
| Gao, J; Liu, Y; Ren, C; Wei, L; Xu, G; Zhang, Z | 1 |
| Gao, P; Li, F; Wang, X; Zhang, X; Zhang, Z | 1 |
| Doğan, G; Karaca, O | 1 |
| Fan, Y; Liu, X; Sun, D; Wang, J; Yang, M; Zhang, J | 1 |
| Li, H; Lu, C; Xu, L; Yao, W; Zheng, B; Zhou, J | 1 |
| Albert, M; Bernard, F; Bilodeau, V; Burry, L; Frenette, AJ; Saavedra-Mitjans, M; Williamson, DR | 1 |
| Hao, FG; Huang, GR | 1 |
| Feng, X; Jiao, W; Ma, W; Wang, Y; Zhu, J | 1 |
| Kii, N; Sawada, A; Tachibana, S; Yamakage, M; Yoshikawa, Y | 1 |
| Han, XR; Lu, J; Shen, M; Wang, S; Wang, YJ; Wen, X; Wu, DM; Zhang, MH; Zheng, YL; Zhou, XM | 1 |
| Chen, J; Gao, X; Kulwin, C; Lin, B; Vogel, T; Wu, J | 1 |
| Cui, JZ; Feng, Y; Wang, KJ; Zhang, HA; Zhang, MH; Zhou, XM | 1 |
| Bindra, A; Chouhan, RS; Radhakrishna, N; Singh, S | 1 |
| Bo, L; Deng, X; Wang, C; Wang, H; Wang, Y; Zhang, D | 1 |
| Guo, X; Li, H; Ruan, X; Xu, L; Ying, Y; Zhang, S; Zheng, B | 1 |
| Alam, A; Hana, Z; Jin, Z; Ma, D; Suen, KC | 1 |
| Deng, Z; Gao, P; Li, F; Liu, H; Wang, X; Zhang, X | 1 |
| Longrois, D; Quintin, L | 1 |
| Constantin, JM; Perbet, S | 1 |
| Godoy, DA; Lubillo-Montenegro, S; Murillo-Cabezas, F; Tolosa, K | 1 |
| Bonds, BW; Boswell, S; Devabhakthuni, S; Hesselton, K; Kufera, JA; Pajoumand, M; Scalea, TM; Stein, DM | 1 |
| Humble, SS; Leath, TC; Marshall, MD; Pandharipande, PP; Patel, MB; Sun, DZ; Wilson, LD | 1 |
3 review(s) available for dexmedetomidine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
The Impact of Sedative Choice on Intracranial and Systemic Physiology in Moderate to Severe Traumatic Brain Injury: A Scoping Review.
Topics: Adult; Analgesics, Opioid; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intracranial Hypertension; Ketamine; Propofol; Prospective Studies | 2023 |
The Role of miRNAs in Dexmedetomidine's Neuroprotective Effects against Brain Disorders.
Topics: Anesthetics; Brain Injuries, Traumatic; Dexmedetomidine; Humans; MicroRNAs; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes | 2022 |
Surgery, neuroinflammation and cognitive impairment.
Topics: Animals; Brain Injuries, Traumatic; Cognitive Dysfunction; Dementia; Dexmedetomidine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibuprofen; Inflammation; Postoperative Complications | 2018 |
3 trial(s) available for dexmedetomidine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Effects of dexmedetomidine vs sufentanil during percutaneous tracheostomy for traumatic brain injury patients: A prospective randomized controlled trial.
Topics: Adult; Brain Injuries, Traumatic; Cough; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Laryngismus; Male; Middle Aged; Prospective Studies; Sufentanil; Tracheostomy | 2019 |
Comparison of effect of dexmedetomidine and lidocaine on intracranial and systemic hemodynamic response to chest physiotherapy and tracheal suctioning in patients with severe traumatic brain injury.
Topics: Adolescent; Adult; Brain Injuries, Traumatic; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Intracranial Pressure; Lidocaine; Male; Middle Aged; Physical Therapy Modalities; Prospective Studies; Respiration, Artificial; Suction; Young Adult | 2018 |
Cooperative sedation: An option for the management of agitation in moderate traumatic brain injury.
Topics: Accidental Falls; Accidents, Traffic; Adult; Aged, 80 and over; Analgesics; Brain Injuries, Traumatic; Clinical Protocols; Conscious Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Psychomotor Agitation; Tomography, X-Ray Computed; Trauma Severity Indices; Young Adult | 2017 |
22 other study(ies) available for dexmedetomidine and Encephalopathy, Traumatic
| Article | Year |
|---|---|
Tailored Therapeutic Doses of Dexmedetomidine in Evolving Neuroinflammation after Traumatic Brain Injury.
Topics: Animals; Anti-Inflammatory Agents; Brain Injuries, Traumatic; Dexmedetomidine; Disease Models, Animal; Humans; Interleukin-1beta; Mice; Neuroinflammatory Diseases; NLR Family, Pyrin Domain-Containing 3 Protein | 2022 |
Assessment of the effects of dexmedetomidine on outcomes of traumatic brain injury using propensity score analysis.
Topics: Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypotension; Propensity Score; Seizures | 2022 |
Dexmedetomidine Alters the Inflammatory Profile of Rat Microglia In Vitro.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brain Injuries, Traumatic; Cytokines; Dexmedetomidine; Inflammation; Interleukin-10; Lipopolysaccharides; Microglia; Poly I; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2023 |
Clinical characteristics and prognosis of paroxysmal sympathetic hyperactivity in patients with severe nontraumatic brain injury.
Topics: Autonomic Nervous System Diseases; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Prognosis; Prospective Studies | 2023 |
Dexmedetomidine Attenuates Neuroinflammatory-Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathway.
Topics: Animals; Apoptosis; Brain; Brain Injuries, Traumatic; Dexmedetomidine; Inflammation; Neuroprotective Agents; NF-E2-Related Factor 2; Rats; Signal Transduction | 2019 |
The effects of dexmedetomidine in increased intestinal permeability after traumatic brain injury: An experimental study.
Topics: Animals; Brain Injuries, Traumatic; Cytokines; Dexmedetomidine; Disease Models, Animal; Inflammation; Intestinal Absorption; Intestinal Mucosa; Rats | 2020 |
Dexmedetomidine attenuates endoplasmic reticulum stress-induced apoptosis and improves neuronal function after traumatic brain injury in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Brain; Brain Injuries, Traumatic; Dexmedetomidine; Endoplasmic Reticulum Stress; Male; Mice; Neurons; Neuroprotective Agents | 2020 |
Dexmedetomidine inhibits inflammatory response and autophagy through the circLrp1b/miR-27a-3p/Dram2 pathway in a rat model of traumatic brain injury.
Topics: Animals; Anti-Inflammatory Agents; Autophagy; Behavior, Animal; Brain; Brain Injuries, Traumatic; Dexmedetomidine; Disease Models, Animal; Gene Expression Regulation; Inflammation Mediators; Male; MicroRNAs; Rats, Sprague-Dawley; RNA, Circular; Signal Transduction | 2020 |
Safety of dexmedetomidine for the control of agitation in critically ill traumatic brain injury patients: a descriptive study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Behavioral Symptoms; Benzodiazepines; Body Weight; Brain Injuries, Traumatic; Comorbidity; Critical Illness; Dexmedetomidine; Drug Therapy, Combination; Female; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Retrospective Studies; Sex Factors; Substance-Related Disorders; Trauma Severity Indices | 2021 |
Dexmedetomidine Inhibits Inflammation to Alleviate Early Neuronal Injury via TLR4/NF-κB Pathway in Rats with Traumatic Brain Injury.
Topics: Animals; Apoptosis; Autophagy; Brain Injuries, Traumatic; Cytokines; Dexmedetomidine; Disease Models, Animal; Inflammation; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Toll-Like Receptor 4 | 2021 |
Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Autophagy; Beclin-1; Brain; Brain Injuries; Brain Injuries, Traumatic; Cell Survival; Cytokines; Dexmedetomidine; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Reactive Oxygen Species; Signal Transduction | 2021 |
Dexmedetomidine Ameliorates Perioperative Neurocognitive Disorders by Suppressing Monocyte-Derived Macrophages in Mice With Preexisting Traumatic Brain Injury.
Topics: Animals; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Interleukin-1beta; Macrophages; Male; Mice; Mice, Inbred C57BL; Neurocognitive Disorders | 2022 |
Dexmedetomidine exerts neuroprotective effect via the activation of the PI3K/Akt/mTOR signaling pathway in rats with traumatic brain injury.
Topics: Animals; Apoptosis; Avoidance Learning; Beclin-1; Blotting, Western; Brain; Brain Injuries, Traumatic; Claudin-5; Cytokines; Dexmedetomidine; Enzyme-Linked Immunosorbent Assay; Inflammation Mediators; Microtubule-Associated Proteins; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Zonula Occludens-1 Protein | 2017 |
Neuroprotective effect of dexmedetomidine in a murine model of traumatic brain injury.
Topics: Animals; Brain Injuries, Traumatic; Cerebral Cortex; Dexmedetomidine; Disease Models, Animal; Hippocampus; Male; Mice; Neuroprotective Agents | 2018 |
Neuroprotective effects of dexmedetomidine on traumatic brain injury: Involvement of neuronal apoptosis and HSP70 expression.
Topics: Animals; Apoptosis; Biomarkers; Brain Edema; Brain Injuries, Traumatic; Dexmedetomidine; Hippocampus; HSP70 Heat-Shock Proteins; Immunohistochemistry; Male; Neurons; Neuroprotective Agents; Rats; Spatial Learning | 2018 |
Dexmedetomidine Protects Against Traumatic Brain Injury-Induced Acute Lung Injury in Mice.
Topics: Acute Lung Injury; Animals; Brain Injuries, Traumatic; Bronchoalveolar Lavage Fluid; Dexmedetomidine; HMGB1 Protein; Lung; Male; Mice; Mice, Inbred C57BL; Models, Animal; Protective Agents; Pulmonary Edema; Receptor for Advanced Glycation End Products; Signal Transduction | 2018 |
Administration of Dexmedetomidine inhibited NLRP3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats.
Topics: Animals; Brain Injuries, Traumatic; Caspase 1; Dexmedetomidine; Disease Models, Animal; Hippocampus; Humans; Inflammasomes; Microglia; Neurons; NLR Family, Pyrin Domain-Containing 3 Protein; Rats | 2018 |
Dexmedetomidine reduces oxidative stress and provides neuroprotection in a model of traumatic brain injury via the PGC-1α signaling pathway.
Topics: Animals; Apoptosis; Brain; Brain Injuries, Traumatic; Dexmedetomidine; Male; Neuroprotective Agents; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Dexmedetomidine: Superiority trials needed?
Topics: Adrenergic alpha-2 Receptor Agonists; Brain Injuries, Traumatic; Contraindications; Critical Care; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Respiratory Distress Syndrome | 2016 |
Dexmedetomidine: Superiority trials needed? Reply.
Topics: Adrenergic alpha-2 Receptor Agonists; Brain Injuries, Traumatic; Contraindications; Critical Care; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Respiratory Distress Syndrome | 2016 |
Dexmedetomidine as an adjunct for sedation in patients with traumatic brain injury.
Topics: Abbreviated Injury Scale; Adult; Baltimore; Brain Injuries, Traumatic; Dexmedetomidine; Female; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Hypotension; Male; Prospective Studies; Treatment Outcome | 2016 |
ICU sedation with dexmedetomidine after severe traumatic brain injury.
Topics: Adult; Analgesics, Non-Narcotic; Blood Pressure; Brain Injuries, Traumatic; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Intensive Care Units; Male; Middle Aged; Retrospective Studies; Young Adult | 2016 |