dexmedetomidine has been researched along with Encephalopathy, Toxic in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 7 (35.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Gao, R; Xu, S | 1 |
| Badulescu, AV; Burlacu, CC; Buzoianu, AD; Mitre, AO; Neag, MA; Sirbu, AC | 1 |
| Brambrink, AM; Grafe, MR; Neudecker, V; Perez-Zoghbi, JF; Zhu, W | 1 |
| Fan, J; Han, X; Leng, Y; Liu, Y; Ma, X; Xue, X; Yu, J | 1 |
| Suo, L; Wang, M | 1 |
| Danzer, SC; Ewing, L; Hofacer, RD; Joseph, B; Lee, JR; Lee, SY; Loepke, AW; Upton, B; Zhang, B | 1 |
| Cao, YY; Ding, XD; Li, L; Zhao, GY | 1 |
| Andropoulos, DB | 1 |
| Brambrink, AM; Grafe, MR; Perez-Zoghbi, JF; Zhu, W | 1 |
| Andropoulos, D; Ma, D; Maze, M; Sanders, RD | 1 |
| Bo, LJ; Dong, ZM; Yu, PX; Zhang, FZ | 1 |
| de Graaff, JC; Essink, H; Hoeks, SE; Tibboel, D; van Hoorn, CE | 1 |
| Dai, WX; Lin, CX; Shu, LP; Wang, HL; Wei, QF; Zhang, GY; Zheng, RF | 1 |
| Guo, J; Han, D; Li, H; Luo, J | 1 |
| Han, L; Jiang, JH; Liu, MZ; Peng, YM; Qian, XL; Wang, QD; Zhang, JM; Zhang, W; Zhou, YB | 1 |
| Bekker, A; Eloy, JD; Li, J; Nadavaluru, PR; Xiong, M; Ye, JH; Zuo, W | 1 |
| Chen, J; He, D; Hu, J; Li, L; Liang, Y; Qin, Y; Wei, Y; Xiao, Q; Xie, Y; Zhong, Y | 1 |
| Alizadeh, L; Arhami-Dolatabadi, A; Daneshbod, Y; Hosseinian, MA; Khandaghy, M; Memari, E; Mirabotalebi, M; Mirkheshti, A; Shirian, S | 1 |
| Brummett, CM; Lydic, R; Norat, MA; Palmisano, JM | 1 |
| Bayliff, S; Bernard, PA; Hayes, D; McCabe, T | 1 |
3 review(s) available for dexmedetomidine and Encephalopathy, Toxic
| Article | Year |
|---|---|
The Role of miRNAs in Dexmedetomidine's Neuroprotective Effects against Brain Disorders.
Topics: Anesthetics; Brain Injuries, Traumatic; Dexmedetomidine; Humans; MicroRNAs; Neurodegenerative Diseases; Neuroprotective Agents; Neurotoxicity Syndromes | 2022 |
Effect of Anesthesia on the Developing Brain: Infant and Fetus.
Topics: Age Factors; Anesthesia; Anesthetics; Animals; Apoptosis; Behavior, Animal; Brain; Child; Child Behavior; Child Development; Child, Preschool; Dexmedetomidine; Disease Models, Animal; Gestational Age; Humans; Infant; Infant Behavior; Neurogenesis; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes | 2018 |
A systematic review and narrative synthesis on the histological and neurobehavioral long-term effects of dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Child, Preschool; Cognition; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Mental Status and Dementia Tests; Neurotoxicity Syndromes; Randomized Controlled Trials as Topic | 2019 |
17 other study(ies) available for dexmedetomidine and Encephalopathy, Toxic
| Article | Year |
|---|---|
Dexmedetomidine regulates sevoflurane-induced neurotoxicity through the miR-330-3p/ULK1 axis.
Topics: Anesthetics, Inhalation; Animals; Apoptosis; Autophagy-Related Protein-1 Homolog; Dexmedetomidine; MicroRNAs; Mitophagy; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sevoflurane | 2021 |
Neurotoxicity of sub-anesthetic doses of sevoflurane and dexmedetomidine co-administration in neonatal rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Neurotoxicity Syndromes; Rats, Wistar; Respiratory Rate; Sensory Thresholds; Sevoflurane | 2020 |
Effects of local dexmedetomidine administration on the neurotoxicity of ropivacaine for sciatic nerve block in rats.
Topics: Animals; Apoptosis; Autonomic Nerve Block; Caspase 3; Chemotherapy, Adjuvant; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression Regulation; Male; Neurotoxicity Syndromes; Rats; Ropivacaine; Sciatic Nerve | 2020 |
Dexmedetomidine alleviates sevoflurane-induced neurotoxicity via mitophagy signaling.
Topics: Animals; Dexmedetomidine; Mitophagy; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction | 2020 |
Effect of dexmedetomidine on sevoflurane-induced neurodegeneration in neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Cell Death; Dexmedetomidine; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Wistar; Sevoflurane | 2021 |
Dexmedetomidine Reduces the Lidocaine-Induced Neurotoxicity by Inhibiting Inflammasome Activation and Reducing Pyroptosis in Rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Dexmedetomidine; Inflammasomes; Lidocaine; Male; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Phosphorylation; Protein Kinase C-delta; Pyroptosis; Rats, Sprague-Dawley; Spinal Cord | 2021 |
Dexmedetomidine-mediated neuroprotection against sevoflurane-induced neurotoxicity extends to several brain regions in neonatal rats.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Dexmedetomidine; Disease Models, Animal; Hypnotics and Sedatives; Neuroprotection; Neurotoxicity Syndromes; Rats; Rats, Wistar; Sevoflurane | 2017 |
Theseus, the Labyrinth, and the Minotaur of anaesthetic-induced developmental neurotoxicity.
Topics: Anesthetics; Animals; Dexmedetomidine; Ear, Inner; Neurotoxicity Syndromes; Rats; Sevoflurane | 2017 |
Dexmedetomidine mitigates sevoflurane-induced cell cycle arrest in hippocampus.
Topics: Anesthetics; Animals; Brain-Derived Neurotrophic Factor; Cell Cycle Checkpoints; Dexmedetomidine; Hippocampus; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sevoflurane; Signal Transduction | 2018 |
Dose-dependent neurotoxicity caused by the addition of perineural dexmedetomidine to ropivacaine for continuous femoral nerve block in rabbits.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Dexmedetomidine; Dose-Response Relationship, Drug; Femoral Nerve; Nerve Block; Neurotoxicity Syndromes; Rabbits; Ropivacaine | 2019 |
[Comparison of dexmedetomidine and midazolam on neurotoxicity in neonatal mice].
Topics: Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Dexmedetomidine; Hippocampus; Mice; Mice, Inbred C57BL; Midazolam; Neurons; Neurotoxicity Syndromes; Proto-Oncogene Proteins c-bcl-2 | 2013 |
Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Anesthetics, General; Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Cognition Disorders; Dexmedetomidine; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; Inflammation Mediators; Maze Learning; Mice, Inbred BALB C; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Postoperative Complications; Random Allocation; Splenectomy | 2015 |
Dexmedetomidine Attenuates Neurotoxicity Induced by Prenatal Propofol Exposure.
Topics: Anesthetics, Intravenous; Animals; Blotting, Western; Brain; Calcium-Binding Proteins; Caspase 3; Dexmedetomidine; Disease Models, Animal; Female; Hypnotics and Sedatives; Microfilament Proteins; Neurotoxicity Syndromes; Pregnancy; Prenatal Exposure Delayed Effects; Propofol; Rats; Rats, Sprague-Dawley | 2016 |
Dexmedetomidine pretreatment attenuates propofol‑induced neurotoxicity in neuronal cultures from the rat hippocampus.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthetics, Intravenous; Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dexmedetomidine; Female; Hippocampus; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Propofol; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2016 |
Comparison of histopathological effects of perineural administration of bupivacaine and bupivacaine-dexmedetomidine in rat sciatic nerve.
Topics: Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Disease Models, Animal; Microscopy, Electron, Transmission; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2016 |
Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat.
Topics: Analgesics, Non-Narcotic; Anesthetics, Local; Animals; Bupivacaine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Inflammation; Male; Models, Animal; Motor Activity; Nerve Block; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Sensation; Sodium Chloride; Time Factors | 2008 |
Successful treatment of ifosfamide neurotoxicity with dexmedetomidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Antidotes; Antineoplastic Agents, Alkylating; Child, Preschool; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Ifosfamide; Methylene Blue; Neurotoxicity Syndromes; Rhabdomyosarcoma; Treatment Outcome | 2010 |