Page last updated: 2024-08-24

dexmedetomidine and Delirium

dexmedetomidine has been researched along with Delirium in 262 studies

Research

Studies (262)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (5.34)29.6817
2010's136 (51.91)24.3611
2020's112 (42.75)2.80

Authors

AuthorsStudies
Hong, H; Li, M; Sessler, DI; Wang, DX; Wang, G; Zhang, DZ; Zhang, Y; Zhu, SN1
Bilotta, F; Trombi, M; Tsaousi, G1
Bai, Y; Dong, R; Liu, X; Qin, B; Song, X; Tian, S; Yang, D; Yang, M1
Dong, J; Li, R; Li, S; Lin, N; Liu, X; Peng, Y; Wang, D; Wang, J; Zeng, M1
Bardes, JM; Burruss, S; Butt, A; Chang, G; Cochran-Yu, M; DeLa'O, C; Dorricott, A; Duletzke, NT; Fiorentino, MN; Glass, N; Grigorian, A; Guillamondegui, OD; Gutierrez, A; Kaafarani, H; Kemmer, H; Kincaid, M; Krause, C; Kwon, E; LaRiccia, A; Leneweaver, K; Ley, E; Lieser, MJ; Lombardo, SR; Luo-Owen, X; McArthur, K; Moradian, S; Mukherjee, K; Naar, L; Nahmias, J; Nemeth, Z; Nunez, J; Posluszny, J; Swentek, L; Toscano, S; Turay, D; Wydo, SM1
Chen, K; Cheng, KM; Duan, YQ; Gao, HR; Gu, HQ; He, X; Li, HL; Miao, MY; Xu, SS; Yang, YL; Zhang, L; Zhou, JX1
An, XH; Dong, CH; Gao, CN; Li, DC; Li, N; Tan, Q; Yang, L1
Bhalla, RK; Brohan, J; Chitnis, S; Grey, R; Klein, R; Mullane, D; Noronha, A; Paje, H; Sidhu, J1
Chan, T; Dervan, LA; Koth, AM; Tjoeng, YL; Watson, RS1
Carval, A; Cattan, P; Plaud, B; Valent, A1
Bu, X; Ge, Y; Wang, S; Wang, X; Wang, Y; Yi, H; Zhao, N1
Hu, J; Maze, M; Zhang, Y1
Li, B; Li, H; Ma, K; Shao, X; Wu, J1
Chan, YS; Chang, CH; Chen, DY; Chen, SW; Cheng, YT; Chou, AH; Chu, PH; Lee, KT; Liu, KS; Wu, VC1
Desai, N; Onwochei, DN; Patel, M1
Jørgen Jennum, P; Knudsen, T; Oxlund, J; Sörberg, M; Toft, P1
Amour, J; Bougle, A; Consigny, M; Durand, M; Eddi, D; Futier, E; Gargadennec, T; Huet, O; Kerforne, T; Lasocki, S; Nesseler, N; Oilleau, JF; Rozec, B1
Fusi-Schmidhauser, T; Gaertner, J1
Kong, G; Liu, J; Tang, Y; Wang, Y; Wei, L; Zhao, Y1
Ask, J; Chlan, LL; Gajic, O; Mandrekar, J; Skaar, DJ; Tracy, MF; Weinert, CR1
Al Duhailib, Z; Alhazzani, W; Alshahrani, M; Alshamsi, F; Carayannopoulos, KL; Centofanti, J; Chaudhuri, D; Devlin, JW; Ergan, B; Granholm, A; Holbrook, A; Honarmand, K; Karachi, T; Khorochkov, E; Lewis, K; Møller, MH; Needham, DM; Nishida, O; Pandharipande, P; Perri, D; Piticaru, J; Rochwerg, B; Shehabi, Y; Soth, M; Spatafora, L; Spence, J; Yuan, Y1
Chen, X; Miao, Y; Wan, X; Wu, Y1
Busund, R; Haaverstad, R; Helbostad, JL; Landsverk, SA; Martinaityte, I; Neerland, BE; Norum, HM; Ræder, J; Selbaek, G; Simpson, MR; Skaar, E; Skjærvold, NK; Skovlund, E; Slooter, AJ; Svendsen, ØS; Tønnessen, T; Wahba, A; Wyller, TB; Zetterberg, H1
Feng, X; Wang, Y; Zhao, B1
Chen, Q; Feng, J; Hu, Q; Jia, J; Liao, YH; Liu, X1
Gu, Y; Liu, L; Tang, C; Wei, W; Yao, Y; Zhang, A; Zheng, X; Zhou, M1
Deng, Y; Ju, X; Liu, L; Qin, Z; Wu, Q; Yang, X; Zhang, Y1
Ali, S; Deng, J; Heybati, K; Mohananey, D; Ramakrishna, H; Villablanca, P; Zhou, F1
Shen, P; Wang, Y; Yin, Q; Yu, K; Zhang, S1
Ala-Kokko, T; Erikson, K; Kortelainen, J; Koskenkari, J; Laurila, J1
Gu, L; Lv, Y1
Hayashida, M; Nagaoka, I; Someya, A; Yamaguchi, K; Yamazaki, S1
Lee, EY; Wilcox, ME1
Jennum, PJ; Knudsen, T; Oxlund, J; Sörberg, M; Strøm, T; Toft, P1
Leng, Y; Wang, Y; Yu, S; Zhao, G1
Enomoto, Y; Hiramatsu, Y; Hoshino, H; Inoue, Y; Kato, H; Mathis, BJ; Matsubara, M; Matsuishi, Y; Morita, K; Shimojo, N1
Smith, W; Whitlock, EL1
Bao, Z; Cui, Q; Li, H; Li, M; Li, R; Li, S; Ma, T; Peng, Y; Sessler, DI; Wang, D; Zeng, M; Zhang, X1
Do, SH; Han, SH; Hwang, JW; Kim, H; Na, HS; Shin, HJ; Woo Nam, S; Yim, S1
Alhazzani, W; Beaver, C; Belley-Côté, EP; Benz, A; Borges, FK; D'Aragon, F; He, H; Hedden, M; Jacobsohn, E; Jain, D; Kashani, HH; Kavosh, M; Kloppenburg, S; Kugler, A; Lauw, M; Lin, S; Lucas, A; Mazer, CD; Mokhtari, A; Nishi, C; Piticaru, J; Saud, H; Schulman, S; Sibilio, S; Spence, J; Szczeklik, W; Timmerman, N; Um, K; Wada, C; Wang, E; Whitlock, R; Young, J; Zhang, SY1
Andersen-Ranberg, NC; Barbateskovic, M; Chen, YX; Kronborg, JR; Maagaard, M; Perner, A; Wetterslev, J; Xi, HH1
DeGrado, JR; Goodberlet, MZ; Lupi, KE; Marino, KK; Schuler, BR; Ware, LR1
Behal, M; Bissell, B; Mefford, B; Pandya, K; Robbins, B; Wiegand, A1
Gomon, M; Havrylov, O; Terekhovskyi, A1
Guo, C; Li, CJ; Mu, DL; Wang, BJ; Wang, DX; Xing, MW1
Ding, J; Jia, Y; Li, YN; Sessler, DI; Wang, HB; Wang, JH; Wang, Y; Wu, X; Yan, FX; Yuan, S; Zhang, CB; Zhang, L; Zhang, Z1
Fox, ER; Glowacki, KM; Mazer-Amirshahi, M; Soto, P; Whitledge, JD1
Heinrich, M; Jacob, Y; Kho, W; Müller, A; Pohrt, A; Schneider, B; Spies, C; von Haefen, C1
Cui, Y; Li, XF; Lv, J; Zeng, T; Zhang, Q1
Coburn, M; Dieleman, S; Heller, G; Jardine, M; Payne, T; Sanders, RD; Shehabi, Y1
He, Y; Hou, YB; Ning, RD; Niu, JY; Tao, QY; Yang, N; Yu, JM1
Akça, B; Bilotta, F; Salaj, CS1
Akeju, O; Albanese, M; Baker, S; Houle, TT; Mekonnen, J; Mueller, A; Namirembe, GE; Qu, JZ; Westover, MB; Wiredu, K1
Harada, H; Ikeda, K; Kamei, J; Kato, T; Kitajima, N; Kuriyama, A; Maeda, J; Matsuyama, A; Minami, T; Mizota, T; Ohtsuru, S; Sakai, Y; Sato, Y; Takatani, Y; Ueno, K; Watanabe, H; Yamaji, K; Yamashita, Y1
Cao, S; Gao, Z; Hu, J; Li, C; Tang, J; Wu, Y; Xiong, L1
Dai, L; Qu, X; Wang, H; Wang, L; Wang, X; Wu, Q; Zeng, Y; Zhang, N; Zhou, C; Zhou, Y1
Hughes, LM; Irwin, MG; Nestor, CC; Power, S1
Dračina, N; Drljević Todić, V; Kovač, A; Marković, N; Mladenović, N; Okiljević, B; Pantić, T; Preveden, A; Preveden, M; Tatić, M; Todić, M; Vicković, S; Vujić, V; Zdravković, R; Zec, R1
Alleyne, A; Schellenberg, J; Yu, SY1
Ding, X; Jiang, W; Liu, C; Liu, X; Wei, X; Wen, J; Xu, Y1
Baghdoyan, HA; Li, YW; Lu, Y; Lydic, R; Shi, XY; Wang, L; Zhang, H1
Ali, I; Shokri, H1
De Domenico, P; De Simone, A; Denaro, G; Landoni, G; Lembo, R; Monaco, F; Pieri, M; Rose, S1
Guo, N; Hei, Z; Huang, P; Li, X; Qiu, Z; Xiang, P; Zhang, M; Zhou, S1
Ji, Y; Jiang, M; Liu, Y; Shen, W; Sun, Y1
Arora, RC; Le, ML; Mohammed, MK; Pereira, JV; Sanjanwala, RM1
Guo, C; Hu, J; Li, CJ; Li, XY; Ma, D; Mu, DL; Wang, BJ; Wang, DX1
Abrahm, JL; Hofherr, ML; Rickerson, E1
Everhart, DE; Mulkey, MA1
Gong, Z; Ming, S; Xie, Y; Zhang, X1
Scicutella, A1
Li, HF; Shen, QH; Yuan, XZ; Zhou, XY1
Weeks, SM1
Gaevskiy, DI; Grebenchikov, OA; Landoni, G; Lembo, R; Likhvantsev, VV; Ovezov, AM; Skripkin, YV; Tereshina, AA; Yavorovskiy, AG1
Crowley, KE; Geiger, KL; Hacobian, G; Urben, L1
Huang, L; Peng, W; Wang, L; Zhang, T1
Chai, X; Geng, Q; Hu, Y; Shi, S; Tang, C; Wang, H; Wang, J; Wang, S; Wei, Z; Zhang, Z1
Hou, HJ; Liu, SH; Xue, FS1
Mu, DL1
Barletta, JF; Erstad, BL1
Luo, QP; Wang, HB; Yan, FX; Yuan, S; Zhang, L; Zhang, Z1
Bilotta, F; Pugliese, F1
Ayad, S; Duncan, A; Fang, J; Feider, A; Gillinov, M; Hargrave, J; Hassan, M; Howard-Quijano, K; Karimi, N; Leung, S; Mao, G; Ruetzler, K; Sessler, DI; Trombetta, C; Turan, A1
Cox, CE; Gilstrap, DL; Kram, BL; Kram, SJ; Ohman, KL; Schultheis, JM; Yang, Z1
Jie, Z; Li, C; Lin, C; Tu, H; Zhou, X1
Chen, J; Feng, X; Gao, Z; Hu, J; Maze, M; Zhang, Y; Zhao, S; Zhu, M1
Cheng, KM; Gu, H; He, X; Ma, P; Qu, X; Xu, Y; Zhang, L; Zhou, JX1
Bueno, H; Cortés-Beringola, A; Domínguez-Pérez, L; Martín-Asenjo, R; Maruri, R; Moreno, G; Puerto, E; Vicent, L; Vidán, MT1
Arnold, C1
Hong, Y; Hu, J; Kuriyama, A; Li, S; Luo, A; Sun, R; Wang, S; Zhao, Y1
Gong, CC; Liu, X; Tang, Y; Wang, DF; Xiong, J1
De Kerchove, L; Jacquet, LM; Kahn, D; Khalifa, C; Lemaire, G; Mastrobuoni, S; Momeni, M; Rosal Martins, M; Tircoveanu, R; Van Dyck, M; Watremez, C; Zango, SH1
Chen, J; Hua, W; Wang, H; Xin, X1
Amigoni, A; Sperotto, F1
Barclay, G; Lo, WA; Nangati, Z; Thomas, B1
Lu, Z1
Avramescu, S; Choi, S; Couture, EJ; D'Aragon, F; Djaiani, G; Hedlin, P; Jerath, A; Jones, P; Kaustov, L; Kiss, A; Mapplebeck, JC; Orser, BA; Rajamohan, R; Saha, T; Singh, A; Syed, S; Wong, S1
Abernathy, JH; Bollen, BA; Feng, X; Kertai, MD; Pal, N; Shah, AS; Shotwell, MS; Taylor, MA1
Chen, X; Gan, L; Zhao, X1
Duan, M; Ji, C; Liu, J; Liu, S; Yang, R; Zhao, H; Zhao, R1
Jiang, Y; Li, A; Lin, C; Liu, J; Qin, C1
Bi, X; Wei, J; Zhang, X1
Deng, XM; Li, LX; Li, P; Wang, JF; Xie, J; Zhao, ZZ; Zhu, CL1
Bartoszek, M; Hudson, AJ; McGuire, JM; Sorensen, JS; Vice, TFR; Wilson, JT1
Herman, JA; Kaye, AD; Urits, I; Urman, RD; Viswanath, O1
Chang, YW; Chen, PH; Cheng, HL; Cheng, YJ; Lee, CT; Lee, TS; Tsuang, FY; Wu, CY; Yeh, YC1
Hough, CL; Palakshappa, JA1
Hu, B; Tao, X; Tian, T; Xue, FS1
Adi, A; Chahar, P; Chiu, A; Douglas, A; Fang, J; Ince, I; Lin, J; Mao, G; Sagir, A; Turan, A1
Miao, M; Sun, M; Yang, Y; Zhang, J1
Ali, S; Deng, J; Heybati, K; Zhou, F1
Deng, J; Heybati, K1
Applegate, RL; Ji, FH; Liu, H; Lubarsky, DA; Peng, K; Shen, YP1
Li, Y; Sun, Y; Wang, X; Ye, H; Yuan, X1
Hu, B; Li, JG; Peng, ZY; Rao, X; Wang, J; Zhou, WH1
Cai, Y; Ji, MS; Jin, ZC; Li, Y; Liu, J; Yan, J; Yang, HF; Yu, ZX1
Berian, JR; Robinson, TN; Rosenthal, RA1
Arora, H; Bergese, SD; Candiotti, K; Deiner, S; Flaherty, JH; Jankowski, C; Lee, HB; Lin, HM; Luo, X; Rock, P; Saager, L; Sano, M; Sessler, DI; Shander, A; Sieber, FE1
Blum, A; Gantner, L; Hollinger, A; Ledergerber, K; Marsch, S; Rüegg, S; Siegemund, M; Steiner, LA; Sutter, R; von Felten, S; Zimmermann, S1
Chang, XN; Chen, Y; Dong, CM; Du, H; Wei, BH1
Han, LL; Li, QD; Li, SW; Li, WW; Shi, HY; Wan, XY; Zhang, YL1
Estrup, S; Gøgenur, I; Kjer, CKW; Mathiesen, O; Poulsen, LM1
Bruña, V; Devesa, C; Fernández-Avilés, F; Gonzalez-Saldivar, H; Iglesias, M; Juárez, M; Martínez-Sellés, M; Sousa-Casasnovas, I; Valero-Masa, MJ; Vicent, L1
Kang, Y; Lv, Y; Wang, P; Wang, Z; Xu, B; Yang, J; Zhou, Y1
Ely, EW; Ferrell, BA; Girard, TD; Hughes, CG; Pandharipande, PP; Patel, MB; Scheinin, M; Shintani, AK; Stollings, JL; Thompson, JL; Wilkinson, GR1
Amigoni, A; Blangetti, I; Casella, G; Chelazzi, C; Conti, G; Forfori, F; Garisto, C; Moltrasio, M; Mondardini, MC; Pasero, D; Principi, T; Ricci, Z; Romagnoli, S; Tarantino, F1
Akchurin, RS; Gruzdev, KA; Imaev, TE; Lepilin, MG; Margolina, AA1
Devlin, JW; Duprey, MS; Hill, NS; Skrobik, Y1
Berggren, L; Blomqvist, H; Forsberg, S; Nunes, SL; Sarapohja, T; Sörberg, M; Wickerts, CJ1
Chen, S; Cheng, X; Gu, E; Liu, X; Mei, B; Meng, G; Xu, G; Zhang, M; Zhang, Y1
Girard, TD; Nuzzo, E1
Dodson, CR; Schrift, DS; Straw, LB1
Patanwala, AE; Radosevich, JJ; Shurtleff, V1
Akeju, O; Bilotta, F; Brown, EN; Cudemus, G; D'Alessandro, DA; Deng, H; DiBiasio, A; Gitlin, JA; Hahm, EY; Hobbs, LE; Houle, TT; Ibala, R; Loggia, ML; Pavone, KJ; Qu, J; Shaefi, S; Shelton, KT; Tolis, G; Westover, MB1
Guo, C; Hu, J; Li, CJ; Li, HJ; Mu, DL; Wang, BJ; Wang, DX; Wang, ZH; Zhang, QC1
Hong, G; Hong, KS; Kim, NR; Song, SH1
Li, HL; Ma, D; Maze, M; Meng, ZT; Su, X; Wang, DX; Zhang, DF1
Devlin, JW; Skrobik, Y1
Barrau, S; Drouot, X; Marie, D; Rault, C; Reynaud, F; Rousseau, L; Thille, AW1
Bourguignon, N; Chanques, G; Constantin, JM; Godet, T; Louis, C; Morand, D; Pereira, B1
Gasangwa, D; Marcantonio, ER; Mueller, A; O'Gara, B; Packiasabapathy, S; Patxot, M; Shaefi, S; Shankar, P; Subramaniam, B1
Carr, ZJ; Cios, TJ; Potter, KF; Swick, JT1
Finlayson, E; Whitlock, EL1
Böhm, L; Helbing, DL; Witte, OW1
Cacchione, PZ; Compton, P; Pavone, KJ; Polomano, RC; Winner, L1
Chen, PH; Guo, SL; Hsiao, SY; Huang, WH; Wang, JC; Wong, CS; Yang, TS1
Sun, P; Zhao, W1
Chong, JS; Ng, KT; Shubash, CJ1
Amigoni, A; Brugnaro, L; Campagnano, E; Daverio, M; Dusio, MP; Ferrario, S; Ferrero, F; Mondardini, MC; Rossetti, E; Savron, F; Sperotto, F; Vasile, B; Vitale, F1
Xie, M; Xie, S1
Chen, QC; Ji, FH; Jiang, YH; Liu, HY; Peng, K; Zhang, J1
Gao, W; Hou, J; Liu, L; Wang, Y; Wu, Y; Xia, Z; Yuan, Q; Zhao, B1
Barbateskovic, M; Jakobsen, JC; Maagaard, M; Perner, A; Wetterslev, J2
Bellemare, P; Brindamour, D; Burry, L; Charbonney, E; Dupuis, S; Frenette, AJ; Karzon, S; Perreault, MM; Williamson, DR1
Donovan, AL; Whitlock, EL1
Banner-Goodspeed, V; Eikermann, M; Gallagher, J; Gasangwa, D; Marcantonio, ER; Mathur, P; Mueller, A; O'Gara, B; Packiasabapathy, S; Patxot, M; Shaefi, S; Shankar, P; Subramaniam, B; Talmor, D1
Jin, J; Li, T; Ma, J; Ma, Z; Qiao, L; Shi, C1
Li, S; Luo, A; Sun, R; Wang, S; Yang, C; Zhao, Y1
Hu, X; Huyan, T; Li, Q; Peng, H; Zhang, W; Zhu, Z1
Abrams, D; Agerstrand, C; Brodie, D; Dzierba, AL; Madahar, P; Muir, J1
Lee, S1
Wanek, MR1
Mueller, A; Shankar, P; Subramaniam, B1
Rankin, JA; Then, KL; Ungarian, J1
Aydogan, MS; Colak, C; Durmus, M; Erdogan, MA; Karaman, A; Korkmaz, MF; Ozgül, U; Togal, T; Yucel, A1
Fleming, N; Ji, F; Li, Z; Liu, H; Nguyen, H; Shi, P; Young, N1
Mo, Y; Zimmermann, AE1
Bailey, M; Bass, F; Bellomo, R; Howe, B; McArthur, C; Murray, L; Reade, MC; Seppelt, IM; Shehabi, Y; Webb, S; Weisbrodt, L1
Gerresheim, G; Schwemmer, U1
Ji, F; Li, Z; Liu, H; Moore, P; Young, N1
Flannery, AH; Flynn, JD1
Hato, A; Ikegaki, J; Kimura, Y; Komasawa, N1
Huang, Y; Jiang, H; Lu, Y; Sun, Y1
Beringer, R; Birnie, K; Davies, P; Pickard, A1
Li, J; Wang, Z; Zhang, J1
Hanft, A; Turkel, SB1
Belletti, A; Di Prima, AL; Isella, F; Landoni, G; Nardelli, P; Pasin, L; Taddeo, D; Zangrillo, A1
Allen, JC; Bong, CL; Choo, WL; Lim, E; Siow, YN; Tan, JS; Teo, PB1
Brown, S; Hilliard, N; Mitchinson, S1
Chen, Y; Lin, Y; Qian, B; Wu, W; Yao, Y; Ye, H1
Huang, F; Jin, J; Kong, J; Liu, S; Wang, J; Xu, H; Yang, X1
Chen, X; Ding, S; Jiang, L; Li, Y; Liu, S; Tang, X; Yan, H; Yin, X; Zhang, J; Zhang, L1
Bailey, CR; Wong, DD1
Gao, C; Li, B; Wang, H; Wu, H1
Boyle, WA; Drewry, AM; Fagley, RE; Field, RR; Kollef, MH; Lieu, A; Micek, ST; Olatunde, J; Skrupky, LP; Varghese, L; Wessman, B1
Almeida, OP; Ford, AH1
Chen, ZF; Guo, Y; Jiang, H; Li, QF; Sun, LL1
Bozza, FA; do Brasil, PE; Ely, EW; Salluh, JI; Serafim, RB; Soares, M; Tura, BR1
Gao, C; Li, Z; Liu, R; Yang, X1
Berezenko, MN; Borisov, AY; Gubajdullin, RR; Makhlaj, AV; Pasechnik, IN; Sal'nikov, PS; Teplyakova, AN1
Keating, GM1
Bala, I; Bhatia, N; Dwivedi, D; Makkar, JK; Singh, PM1
Giometti, R; Weeks, SM; Woods, AD1
Gao, M; Guo, W; Liu, Y; Ma, L; Ma, Y1
Carroll, J; Djaiani, G; Fedorko, L; Katznelson, R; Rao, V; Silverton, N; Styra, R1
Brudney, S; Bucklin, MH; Gagliardi, JP; Muzyk, AJ; Nelson, S1
Jafra, A; Jain, D; Jain, K; Makkar, JK1
Allen, J; Bong, C; Lim, E; Siow, YN; Tan, J1
Hua, X; Lin, L; Mo, L; Pan, W; Wang, Y; Zhou, G1
Kersten, A; Reith, S1
Dong, C; Feng, F; Li, J; Qi, Y; Song, R; Yang, J; Yang, Z; Zhang, H1
Hughes, CG; King, AB; Orena, EF1
Jin, F; Li, J; Li, Z; Liu, J; Sun, X; Zhang, X1
Baeza, N; Cabré, L; Calizaya, M; Carrasco, G; Gimeno, G; Manzanedo, D; Portillo, E1
Bailey, M; Bellomo, R; Bersten, A; Cheung, B; Davies, A; Delaney, A; Eastwood, GM; Ghosh, A; Harley, N; Knight, D; McGuiness, S; Mulder, J; O'Donoghue, S; Reade, MC; Simpson, N; van Haren, F; Young, P1
Ely, EW; Pandharipande, PP1
Dong, C; Li, J; Song, R; Yang, J1
An, Y; Feng, Y; Liu, D; Lyu, J1
Gao, XJ; Li, J; Li, T; Li, ZB; Lu, X; Xu, L; Zhang, J1
Fujisawa, T; Fujiwara, A; Kido, H; Komasawa, N; Minami, T1
Prough, DS; Teegarden, BM1
Choi, JY; Gwak, MS; Joh, JW; Kim, GS; Kim, JM; Kim, SJ; Ko, JS; Kwon, CH; Lee, S; Lee, SK; Park, JB1
Atkins, Z; Boyd, D; Cheng, H; Ji, F; Li, Z; Liu, H; Young, N1
Amaral, A; Hamilton, M1
Bailey, M; Bellomo, R; Reade, MC1
Cui, F; Li, HL; Ma, D; Maze, M; Meng, ZT; Su, X; Wang, DX; Wu, XH; Zhu, SN; Zhu, X1
Eberwein, KA; Ratliff, PD; Schickli, MA; Short, MR1
Day, RO; Graham, RI; Tay, EM1
Dziodzio, JT; Fontaine, GV; Fraser, GL; Gagnon, DJ; Lerwick, PA; Lucas, FL; Miller, RR; Riker, RR; Sihler, KC; Smith, KE1
Dotson, B1
Coburn, M; Eisert, A; Van Waesberghe, J1
Cao, JL; Pei, YP; Wei, JQ; Zhang, YY1
Fang, X; Jin, Y; Liu, X; Song, F; Song, S; Xie, G; Zhang, K1
Amusina, O; Leikin, JB1
Avramescu, S; Choi, S; Orser, BA; Wang, DS1
Ma, D; Su, X; Wang, DX1
Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB1
Areosa Sastre, A; Lonergan, E; Luxenberg, J; Wyller, TB1
Bokesch, PM; Byrne, DW; Ceraso, D; Ely, EW; Koura, F; Margolis, BD; Riker, RR; Rocha, MG; Shehabi, Y; Whitten, P; Wisemandle, W1
Ainslie, WR; Bates, S; Bellomo, R; Goldsmith, D; O'Sullivan, K; Reade, MC1
Page, VJ1
Arias, LM; Dunn, GN; Kimball, JN; O'Brien, EM; Rosenquist, PB; Smith, B1
Bass, F; Campbell, M; Chen, J; Grant, P; Hammond, N; Shehabi, Y; Wolfenden, H1
Areosa Sastre, A; Lonergan, E; Luxenberg, J1
Dasta, JF; Gerlach, AT; Murphy, CV1
Yuen, VM1
Bliesener, B; Kleinschmidt, S1
Ely, EW; Girard, TD; Herr, DL; Maze, M; McGrane, S; Pandharipande, PP; Sanders, RD; Shintani, AK; Thompson, JL1
Bruno, JJ; Warren, ML1
Kress, JP1
Bokesch, PM; Ely, EW; Riker, RR; Shehabi, Y; Shintani, A; Wisemandle, W1
Coursin, DB; Joffe, A1
Prommer, E1
Frontera, JA1
Aykac, Z; Can, Y; Coruh, T; Kehlibar, T; Ozler, A; Tarhan, A; Yapici, F; Yapici, N1
Cramolini, M; Mountain, BW; Newman, M; Smithson, L; Wyatt, TH1
Steiner, LA1
Bronster, D; Nomoto, K; Scurlock, C1
Ely, EW; Hipp, DM1
Anitescu, M; Patil, SK1
Banayan, D; Bhalerao, S; Groen, JA; Gupta, S; Xu, S1
Al-Qadhee, NS; Devlin, JW; Skrobik, Y1
Matsuda, T; Matsuzaki, S; Tamada, N; Yamaguchi, Y1
Anger, KE1
Bruhn, A; Bugedo, G; Castillo, L; Hernández, G; Mellado, P; Romero, C1
Berkenbosch, JW; Russo, P; Tobias, JD1
Clyde, MC; Kalarickal, PL; Ramadhyani, U; Shukry, M1
Arslan, M; Isik, B; Kurtipek, O; Tunga, AD1
Kobayashi, A; Kotani, T; Oda, Y; Okuda, T1
Bernard, GR; Deppen, SA; Dittus, RS; Ely, EW; Girard, TD; Herr, DL; Jackson, JC; Maze, M; Miller, RR; Pandharipande, PP; Pun, BT; Shintani, AK; Stiles, RA; Thompson, JL1
Barletta, JF; Devlin, JW1

Reviews

69 review(s) available for dexmedetomidine and Delirium

ArticleYear
Dexmedetomidine and paralytic exposure after damage control laparotomy: risk factors for delirium? Results from the EAST SLEEP-TIME multicenter trial.
    European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022, Volume: 48, Issue:3

    Topics: Adult; Delirium; Dexmedetomidine; Female; Humans; Intensive Care Units; Laparotomy; Multicenter Studies as Topic; Pregnancy; Respiration, Artificial; Retrospective Studies; Risk Factors; Sleep

2022
A systematic review and meta-analysis of the clinical efficacy of the intravenous injection of dexmedetomidine in ICU patients with hyperactive brain syndrome.
    Annals of palliative medicine, 2022, Volume: 11, Issue:1

    Topics: Brain; Delirium; Dexmedetomidine; Humans; Injections, Intravenous; Intensive Care Units; Psychomotor Agitation; Treatment Outcome

2022
Influence of perioperative dexmedetomidine on the incidence of postoperative delirium in adult patients undergoing cardiac surgery.
    British journal of anaesthesia, 2022, Volume: 129, Issue:1

    Topics: Adult; Bradycardia; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Incidence; Postoperative Complications

2022
Dexmedetomidine: a magic bullet on its way into palliative care-a narrative review and practice recommendations.
    Annals of palliative medicine, 2022, Volume: 11, Issue:4

    Topics: Analgesics, Opioid; Delirium; Dexmedetomidine; Humans; Palliative Care; Prospective Studies; Psychomotor Agitation

2022
Dexmedetomidine vs other sedatives in critically ill mechanically ventilated adults: a systematic review and meta-analysis of randomized trials.
    Intensive care medicine, 2022, Volume: 48, Issue:7

    Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Randomized Controlled Trials as Topic; Respiration, Artificial

2022
Effect of dexmedetomidine for prevention of acute kidney injury after cardiac surgery: an updated systematic review and meta-analysis.
    Renal failure, 2022, Volume: 44, Issue:1

    Topics: Acute Kidney Injury; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Intensive Care Units

2022
Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials.
    British journal of anaesthesia, 2022, Volume: 129, Issue:4

    Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial

2022
Sleep in the intensive care unit.
    Current opinion in pulmonary medicine, 2022, 11-01, Volume: 28, Issue:6

    Topics: Critical Care; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Melatonin; Sleep

2022
A Review of the Biological Mechanisms of Dexmedetomidine for Postoperative Neurocognitive Disorders.
    Medical science monitor : international medical journal of experimental and clinical research, 2022, Oct-25, Volume: 28

    Topics: Adjuvants, Anesthesia; Aged; Delirium; Dexmedetomidine; Humans; Neurocognitive Disorders; Postoperative Cognitive Complications

2022
Cardiac surgery, ICU sedation, and delirium: is dexmedetomidine the silver bullet?
    Current opinion in anaesthesiology, 2023, Feb-01, Volume: 36, Issue:1

    Topics: Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units

2023
Effect of perioperative benzodiazepine use on intraoperative awareness and postoperative delirium: a systematic review and meta-analysis of randomised controlled trials and observational studies.
    British journal of anaesthesia, 2023, Volume: 131, Issue:2

    Topics: Aged; Benzodiazepines; Delirium; Dexmedetomidine; Emergence Delirium; Humans; Intraoperative Awareness; Observational Studies as Topic; Randomized Controlled Trials as Topic

2023
Dexmedetomidine for the prevention of delirium in adults admitted to the intensive care unit or post-operative care unit: A systematic review of randomised clinical trials with meta-analysis and Trial Sequential Analysis.
    Acta anaesthesiologica Scandinavica, 2023, Volume: 67, Issue:4

    Topics: Adult; Critical Care; Delirium; Dexmedetomidine; Hospitalization; Humans; Intensive Care Units

2023
Niche Roles for Dexmedetomidine in the Intensive Care Unit.
    The Annals of pharmacotherapy, 2023, Volume: 57, Issue:10

    Topics: Alcoholism; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Substance Withdrawal Syndrome

2023
Effectiveness of dexmedetomidine on postoperative cognitive dysfunction in elderly patients with fracture: A systematic review.
    Medicine, 2023, Mar-17, Volume: 102, Issue:11

    Topics: Aged; Cognition; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Postoperative Cognitive Complications; Postoperative Complications; Randomized Controlled Trials as Topic

2023
A comparation of dexmedetomidine and midazolam for sedation in patients with mechanical ventilation in ICU: A systematic review and meta-analysis.
    PloS one, 2023, Volume: 18, Issue:11

    Topics: Bradycardia; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Respiration, Artificial

2023
Promoting sleep and circadian health may prevent postoperative delirium: A systematic review and meta-analysis of randomized clinical trials.
    Sleep medicine reviews, 2019, Volume: 48

    Topics: Circadian Rhythm; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Postoperative Complications; Randomized Controlled Trials as Topic; Sleep

2019
Trials Focusing on Prevention and Treatment of Delirium After Cardiac Surgery: A systematic Review of Randomized Evidence.
    Journal of cardiothoracic and vascular anesthesia, 2020, Volume: 34, Issue:6

    Topics: Adult; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Europe; Humans; North America

2020
Dexmedetomidine versus propofol sedation in reducing delirium among older adults in the ICU: A systematic review and meta-analysis.
    European journal of anaesthesiology, 2020, Volume: 37, Issue:2

    Topics: Aged; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Respiration, Artificial

2020
Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis.
    Annals of palliative medicine, 2020, Volume: 9, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; China; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Perioperative Care; Postoperative Complications; Randomized Controlled Trials as Topic; Risk Assessment; Surgical Procedures, Operative; Young Adult

2020
The pharmacotherapeutic management of postoperative delirium: an expert update.
    Expert opinion on pharmacotherapy, 2020, Volume: 21, Issue:8

    Topics: Aged; Analgesia; Anesthesia; Antipsychotic Agents; Delirium; Dexmedetomidine; Drug Monitoring; Humans; Melatonin; Postoperative Complications; Practice Guidelines as Topic

2020
Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:8

    Topics: Aged; Delirium; Dexmedetomidine; Humans; Postoperative Complications

2020
Pharmacological Options for Treating Delirium in Critically Ill Adults.
    The American journal of nursing, 2020, Volume: 120, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Antipsychotic Agents; Critical Illness; Delirium; Dexmedetomidine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intensive Care Units; Randomized Controlled Trials as Topic; Respiration, Artificial

2020
Drug dosing in the critically ill obese patient-a focus on sedation, analgesia, and delirium.
    Critical care (London, England), 2020, 06-08, Volume: 24, Issue:1

    Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Benzodiazepines; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Etomidate; Haloperidol; Humans; Ketamine; Obesity; Pain Management; Quetiapine Fumarate

2020
Effect of Dexmedetomidine on Delirium in Elderly Surgical Patients: A Meta-analysis of Randomized Controlled Trials.
    The Annals of pharmacotherapy, 2021, Volume: 55, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Bradycardia; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Length of Stay; Postoperative Cognitive Complications; Randomized Controlled Trials as Topic

2021
Diagnosis, prevention, and management of delirium in the intensive cardiac care unit.
    American heart journal, 2021, Volume: 232

    Topics: Antipsychotic Agents; Coronary Care Units; Delirium; Dementia; Depression; Dexmedetomidine; Diagnosis, Differential; Humans; Hypnotics and Sedatives; Psychotic Disorders; Risk Assessment

2021
Effect of dexmedetomidine on delirium during sedation in adult patients in intensive care units: A systematic review and meta-analysis.
    Journal of clinical anesthesia, 2021, Volume: 69

    Topics: Adult; Delirium; Dexmedetomidine; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Respiration, Artificial

2021
Role of dexmedetomidine in the treatment of delirium in critically ill patients: a systematic review and meta-analysis.
    Minerva anestesiologica, 2021, Volume: 87, Issue:1

    Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans

2021
The Safety and Efficacy Evaluation of Dexmedetomidine for Procedural Sedation and Postoperative Behaviors in Pediatric Populations: A Systematic Review and Meta-analysis.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:1

    Topics: Child; Delirium; Dexmedetomidine; Heart Rate; Humans; Hypnotics and Sedatives; Pain, Postoperative

2022
Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis.
    Journal of clinical anesthesia, 2021, Volume: 73

    Topics: Adult; Aged; Bradycardia; Delirium; Dexmedetomidine; Humans; Hypotension; Postoperative Complications

2021
Effects of dexmedetomidine on neurocognitive disturbance after elective non-cardiac surgery in senile patients: a systematic review and meta-analysis.
    The Journal of international medical research, 2021, Volume: 49, Issue:5

    Topics: China; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Hypotension; Postoperative Complications

2021
Dexmedetomidine reduces the incidence of postoperative delirium after cardiac surgery: a meta-analysis of randomized controlled trials.
    BMC anesthesiology, 2021, 05-18, Volume: 21, Issue:1

    Topics: Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Incidence; Postoperative Complications; Randomized Controlled Trials as Topic

2021
How We Prevent and Treat Delirium in the ICU.
    Chest, 2021, Volume: 160, Issue:4

    Topics: Analgesics, Opioid; Antipsychotic Agents; Critical Care; Delirium; Dexmedetomidine; Early Ambulation; Evidence-Based Practice; Family; Humans; Hypnotics and Sedatives; Implementation Science; Intensive Care Units; Orientation; Pain Management; Patient Care Bundles; Patient Care Team; Respiration, Artificial

2021
Light sedation with dexmedetomidine: a practical approach for the intensivist in different ICU patients.
    Minerva anestesiologica, 2018, Volume: 84, Issue:6

    Topics: Acute Disease; Adult; Cardiac Surgical Procedures; Cerebrovascular Disorders; Child; Conscious Sedation; Critical Care; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Sepsis

2018
Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature.
    Current neurology and neuroscience reports, 2018, 08-06, Volume: 18, Issue:10

    Topics: Aged; Animals; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Postoperative Complications

2018
Evaluating the use of dexmedetomidine for the reduction of delirium: An integrative review.
    Heart & lung : the journal of critical care, 2018, Volume: 47, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Cardiac Surgical Procedures; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Respiration, Artificial

2018
Enhanced Perioperative Safety and Comfort During Airway-Related Surgeries and Procedures With Dexmedetomidine-A Brief Review and Clinical Practice Experience.
    Asian journal of anesthesiology, 2018, Volume: 56, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Airway Obstruction; Delirium; Dexmedetomidine; Fiber Optic Technology; Humans; Patient Safety; Perioperative Care

2018
The effect of dexmedetomidine on delirium and agitation in patients in intensive care: systematic review and meta-analysis with trial sequential analysis.
    Anaesthesia, 2019, Volume: 74, Issue:3

    Topics: Delirium; Dexmedetomidine; Humans; Intensive Care Units; Psychomotor Agitation

2019
Effects of Perioperative Dexmedetomidine on Postoperative Mortality and Morbidity: A Systematic Review and Meta-analysis.
    Clinical therapeutics, 2019, Volume: 41, Issue:1

    Topics: Adult; Bradycardia; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Length of Stay; Postoperative Complications; Randomized Controlled Trials as Topic; Respiration, Artificial

2019
A systematic review of interventions to facilitate extubation in patients difficult-to-wean due to delirium, agitation, or anxiety and a meta-analysis of the effect of dexmedetomidine.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2019, Volume: 66, Issue:3

    Topics: Airway Extubation; Anxiety; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Psychomotor Agitation; Time Factors; Ventilator Weaning

2019
Dexmedetomidine: present and future directions.
    Korean journal of anesthesiology, 2019, Volume: 72, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Patient Selection

2019
Delirium in the Intensive Care Unit: Is Dexmedetomidine Effective?
    Critical care nurse, 2019, Volume: 39, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Critical Care Nursing; Curriculum; Delirium; Dexmedetomidine; Education, Nursing, Continuing; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Practice Guidelines as Topic

2019
Role of dexmedetomidine for the prevention and treatment of delirium in intensive care unit patients.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Critical Care; Delirium; Dexmedetomidine; Humans; Randomized Controlled Trials as Topic

2013
[Dexmedetomidine].
    Der Anaesthesist, 2013, Volume: 62, Issue:8

    Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Bariatric Surgery; Child; Conscious Sedation; Contraindications; Cost-Benefit Analysis; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Electroencephalography; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Magnetic Resonance Imaging; Noninvasive Ventilation

2013
Is dexmedetomidine superior to midazolam as a premedication in children? A meta-analysis of randomized controlled trials.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:8

    Topics: Child; Child, Preschool; Delirium; Dexmedetomidine; Heart Rate; Humans; Hypnotics and Sedatives; Midazolam; Premedication; Prospective Studies; Psychomotor Agitation; Randomized Controlled Trials as Topic

2014
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
    British journal of anaesthesia, 2014, Volume: 112, Issue:6

    Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anesthesia, General; Child; Child Behavior; Child, Preschool; Clonidine; Delirium; Dexmedetomidine; Female; Humans; Infant; Intraoperative Care; Male; Postoperative Complications; Postoperative Period; Randomized Controlled Trials as Topic; Time Factors

2014
The pharmacologic management of delirium in children and adolescents.
    Paediatric drugs, 2014, Volume: 16, Issue:4

    Topics: Adolescent; Antipsychotic Agents; Benzodiazepines; Child; Delirium; Dexmedetomidine; Dibenzothiazepines; Humans; Melatonin; Olanzapine; Quetiapine Fumarate; Risperidone

2014
Dexmedetomidine reduces the risk of delirium, agitation and confusion in critically Ill patients: a meta-analysis of randomized controlled trials.
    Journal of cardiothoracic and vascular anesthesia, 2014, Volume: 28, Issue:6

    Topics: Confusion; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Psychomotor Agitation; Randomized Controlled Trials as Topic

2014
Neurocognitive dysfunction risk alleviation with the use of dexmedetomidine in perioperative conditions or as ICU sedation: a meta-analysis.
    Medicine, 2015, Volume: 94, Issue:14

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Cognition; Critical Care; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Middle Aged; Perioperative Period; Postoperative Complications; Randomized Controlled Trials as Topic; Young Adult

2015
Pharmacological interventions for preventing delirium in the elderly.
    Maturitas, 2015, Volume: 81, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Antipsychotic Agents; Delirium; Dexmedetomidine; Hospitalization; Humans; Melatonin

2015
Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review.
    Journal of critical care, 2015, Volume: 30, Issue:4

    Topics: Antipsychotic Agents; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Haloperidol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Neuroprotective Agents; Postoperative Complications; Quetiapine Fumarate; Respiration, Artificial; Risperidone; Rivastigmine; Treatment Outcome

2015
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
    Drugs, 2015, Volume: 75, Issue:10

    Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; Hypnotics and Sedatives; Propofol

2015
The use of dexmedetomidine as an adjuvant to benzodiazepine-based therapy to decrease the severity of delirium in alcohol withdrawal in adult intensive care unit patients: a systematic review.
    JBI database of systematic reviews and implementation reports, 2015, Volume: 13, Issue:1

    Topics: Adjuvants, Pharmaceutic; Adrenergic alpha-2 Receptor Agonists; Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Case-Control Studies; Cross-Sectional Studies; Delirium; Dexmedetomidine; Female; Humans; Intensive Care Units; Male; Meta-Analysis as Topic; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Severity of Illness Index; Treatment Outcome

2015
Defining the Role of Dexmedetomidine in the Prevention of Delirium in the Intensive Care Unit.
    BioMed research international, 2015, Volume: 2015

    Topics: Aged; Aged, 80 and over; Critical Care; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Incidence; Intensive Care Units; Male; Middle Aged; Randomized Controlled Trials as Topic; Risk Factors; Treatment Outcome

2015
Outcomes of dexmedetomidine treatment in pediatric patients undergoing congenital heart disease surgery: a meta-analysis.
    Paediatric anaesthesia, 2016, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Blood Glucose; Child; Child, Preschool; Delirium; Dexmedetomidine; Heart Defects, Congenital; Hemodynamics; Humans; Hydrocortisone; Hypnotics and Sedatives; Infant; Length of Stay; Postoperative Complications; Randomized Controlled Trials as Topic; Respiration, Artificial; Treatment Outcome; Young Adult

2016
[Delirium and delirium management in critically ill patients].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2016, Volume: 111, Issue:1

    Topics: Checklist; Combined Modality Therapy; Critical Care; Delirium; Dexmedetomidine; Early Ambulation; Evidence-Based Medicine; Haloperidol; Humans; Hypnotics and Sedatives; Orientation; Prognosis; Survival Rate; Treatment Outcome

2016
The role of anesthesia in the prevention of postoperative delirium: a systematic review.
    Minerva anestesiologica, 2016, Volume: 82, Issue:6

    Topics: Analgesics, Non-Narcotic; Anesthesia; Anesthetics; Antipsychotic Agents; Checklist; Delirium; Dexamethasone; Dexmedetomidine; Humans; Ketamine; Postoperative Complications

2016
Dexmedetomidine vs propofol sedation reduces delirium in patients after cardiac surgery: A meta-analysis with trial sequential analysis of randomized controlled trials.
    Journal of critical care, 2017, Volume: 38

    Topics: Coronary Artery Bypass; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Postoperative Complications; Propofol; Randomized Controlled Trials as Topic

2017
Benzodiazepines for delirium.
    The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1

    Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Lorazepam

2009
Benzodiazepines for delirium.
    The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4

    Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Lorazepam

2009
An updated focused review of dexmedetomidine in adults.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:12

    Topics: Adrenergic alpha-Agonists; Adult; Clinical Trials as Topic; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Economics, Pharmaceutical; Humans; Hypnotics and Sedatives; Time Factors

2009
Intensive care unit delirium.
    Critical care nursing clinics of North America, 2010, Volume: 22, Issue:2

    Topics: Algorithms; Antipsychotic Agents; Critical Care; Delirium; Dexmedetomidine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Haloperidol; Humans; Hypnotics and Sedatives; Incidence; Intensive Care Units; Mass Screening; Nurse's Role; Nursing Assessment; Risk Factors; Safety Management; Serotonin Antagonists; Severity of Illness Index

2010
Review article: dexmedetomidine: does it have potential in palliative medicine?
    The American journal of hospice & palliative care, 2011, Volume: 28, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Non-Narcotic; Clinical Trials as Topic; Delirium; Dexmedetomidine; Electron Transport Complex IV; Humans; Palliative Care

2011
Delirium and sedation in the ICU.
    Neurocritical care, 2011, Volume: 14, Issue:3

    Topics: Conscious Sedation; Delirium; Dexmedetomidine; Diagnosis, Differential; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Neurologic Examination; Prognosis; Risk Factors; Survival Rate

2011
Postoperative delirium. part 2: detection, prevention and treatment.
    European journal of anaesthesiology, 2011, Volume: 28, Issue:10

    Topics: Aged; Anesthesia; Antipsychotic Agents; Benzodiazepines; Cholinesterase Inhibitors; Clinical Trials as Topic; Confusion; Critical Care; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Postoperative Complications; Risk; Sensitivity and Specificity

2011
Pharmacological and nonpharmacological management of delirium in critically ill patients.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2012, Volume: 9, Issue:1

    Topics: Analgesics, Non-Narcotic; Antipsychotic Agents; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Humans; Respiration, Artificial

2012
Treatment of delirium following cardiac surgery.
    Journal of cardiac surgery, 2012, Volume: 27, Issue:5

    Topics: Cardiac Surgical Procedures; Cholinesterase Inhibitors; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Israel; Male; Needs Assessment; Perioperative Care; Phenylcarbamates; Postoperative Complications; Preoperative Care; Primary Prevention; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Rivastigmine; Treatment Outcome

2012
Pharmacologic prevention and treatment of delirium in critically ill and non-critically ill hospitalised patients: a review of data from prospective, randomised studies.
    Best practice & research. Clinical anaesthesiology, 2012, Volume: 26, Issue:3

    Topics: Aged; Antipsychotic Agents; Critical Illness; Delirium; Dexmedetomidine; Hospitalization; Humans; Intensive Care Units; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Research Design

2012
Dexmedetomidine: a review of its use for the management of pain, agitation, and delirium in the intensive care unit.
    Current pharmaceutical design, 2013, Volume: 19, Issue:22

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Pain Management; Psychomotor Agitation

2013
Additional experience with dexmedetomidine in pediatric patients.
    Southern medical journal, 2003, Volume: 96, Issue:9

    Topics: Adolescent; Child; Child, Preschool; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units, Pediatric; Male; Psychomotor Agitation; Shivering; Substance Withdrawal Syndrome

2003

Trials

88 trial(s) available for dexmedetomidine and Delirium

ArticleYear
Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled trial.
    BMC anesthesiology, 2021, 09-13, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Beijing; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Incidence; Male; Orthopedic Procedures; Pain, Postoperative; Postoperative Complications; Sufentanil

2021
Effect of remimazolam besylate compared with propofol on the incidence of delirium after cardiac surgery: study protocol for a randomized trial.
    Trials, 2021, Oct-18, Volume: 22, Issue:1

    Topics: Benzodiazepines; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Incidence; Propofol; Prospective Studies; Randomized Controlled Trials as Topic

2021
Effect of dexmedetomidine on postoperative delirium in patients undergoing brain tumour resections: study protocol of a randomised controlled trial.
    BMJ open, 2021, 11-10, Volume: 11, Issue:11

    Topics: Brain Neoplasms; Craniotomy; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Prospective Studies; Randomized Controlled Trials as Topic

2021
Feasibility of low-dose dexmedetomidine for prevention of postoperative delirium after intracranial operations: a pilot randomized controlled trial.
    BMC neurology, 2021, Dec-04, Volume: 21, Issue:1

    Topics: Adult; Delirium; Dexmedetomidine; Double-Blind Method; Feasibility Studies; Humans; Pilot Projects

2021
Nocturnal dexmedetomidine alleviates post-intensive care syndrome following cardiac surgery: a prospective randomized controlled clinical trial.
    BMC medicine, 2021, 12-06, Volume: 19, Issue:1

    Topics: Cardiac Surgical Procedures; Critical Illness; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Prospective Studies

2021
Dexmedetomidine Use in Intensive Care Unit Sedation and Postoperative Recovery in Elderly Patients Post-Cardiac Surgery (DIRECT).
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:3

    Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Quality of Life

2022
Dexmedetomidine and sleep quality in mechanically ventilated critically ill patients: study protocol for a randomised placebo-controlled trial.
    BMJ open, 2022, 03-28, Volume: 12, Issue:3

    Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Randomized Controlled Trials as Topic; Respiration, Artificial; Sleep Quality

2022
Dexmedetomidine after Cardiac Surgery for Prevention of Delirium (EXACTUM) trial protocol: a multicentre randomised, double-blind, placebo-controlled trial.
    BMJ open, 2022, 04-08, Volume: 12, Issue:4

    Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Multicenter Studies as Topic; Quality of Life; Randomized Controlled Trials as Topic

2022
Prevention of dexmedetomidine on postoperative delirium and early postoperative cognitive dysfunction in elderly patients undergoing hepatic lobectomy.
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022, Feb-28, Volume: 47, Issue:2

    Topics: Aged; Aged, 80 and over; Bradycardia; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Hypotension; Interleukin-10; Middle Aged; Postoperative Cognitive Complications; Postoperative Complications; Prospective Studies; Tumor Necrosis Factor-alpha

2022
Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial.
    Trials, 2022, May-16, Volume: 23, Issue:1

    Topics: Aftercare; Analgesics, Opioid; Anxiety; COVID-19; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pandemics; Patient Discharge; Quality of Life; Randomized Controlled Trials as Topic; Respiration, Artificial; Ventilators, Mechanical

2022
A randomized placebo-controlled double-blind study of dexmedetomidine on postoperative sleep quality in patients with endoscopic sinus surgery.
    BMC anesthesiology, 2022, 06-01, Volume: 22, Issue:1

    Topics: Delirium; Dexmedetomidine; Double-Blind Method; Humans; Hydrocortisone; Orexins; Paranasal Sinuses; Postoperative Period; Serotonin; Sleep Quality

2022
Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial.
    BMJ open, 2022, 06-20, Volume: 12, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Cardiac Surgical Procedures; Clonidine; Cognitive Dysfunction; Delirium; Dexmedetomidine; Double-Blind Method; Frailty; Humans; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

2022
Effect Evaluation of Dexmedetomidine Intravenous Anesthesia on Postoperative Agitation in Patients with Craniocerebral Injury by Magnetic Resonance Imaging Based on Sparse Reconstruction Algorithm.
    Contrast media & molecular imaging, 2022, Volume: 2022

    Topics: Algorithms; Anesthesia, Intravenous; Bradycardia; Chills; Craniocerebral Trauma; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Magnetic Resonance Imaging; Postoperative Nausea and Vomiting; Saline Solution

2022
Effects of subanaesthetic S-ketamine on postoperative delirium and cognitive function in elderly patients undergoing non-cardiac thoracic surgery: a protocol for a randomised, double-blinded, placebo-controlled and positive-controlled, non-inferiority tri
    BMJ open, 2022, 08-01, Volume: 12, Issue:8

    Topics: Aged; Cognition; Delirium; Dexmedetomidine; Double-Blind Method; Equivalence Trials as Topic; Humans; Ketamine; Randomized Controlled Trials as Topic; Thoracic Surgery

2022
Efficacy and Safety of Remimazolam Besylate versus Dexmedetomidine for Sedation in Non-Intubated Older Patients with Agitated Delirium After Orthopedic Surgery: A Randomized Controlled Trial.
    Drug design, development and therapy, 2022, Volume: 16

    Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Orthopedic Procedures

2022
Dexmedetomidine potential in attenuating postoperative delirium in elderly patients after total hip joint replacement.
    Revista da Associacao Medica Brasileira (1992), 2022, Volume: 68, Issue:9

    Topics: Aged; Arthroplasty, Replacement, Hip; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Postoperative Complications

2022
Sleep quality and quantity determined by polysomnography in mechanically ventilated critically ill patients randomized to dexmedetomidine or placebo.
    Acta anaesthesiologica Scandinavica, 2023, Volume: 67, Issue:1

    Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Polysomnography; Respiration, Artificial; Sleep Quality

2023
Dexmedetomidine administration during brain tumour resection for prevention of postoperative delirium: a randomised trial.
    British journal of anaesthesia, 2023, Volume: 130, Issue:2

    Topics: Brain Neoplasms; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Pain, Postoperative

2023
Postoperative Delirium after Dexmedetomidine versus Propofol Sedation in Healthy Older Adults Undergoing Orthopedic Lower Limb Surgery with Spinal Anesthesia: A Randomized Controlled Trial.
    Anesthesiology, 2023, 02-01, Volume: 138, Issue:2

    Topics: Aged; Anesthesia, Spinal; Delirium; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Lower Extremity; Propofol

2023
Use of a combination of dexmedetomidine and magnesium sulfate as a multimodal approach to the treatment of alcoholic delirium.
    Anaesthesiology intensive therapy, 2022, Volume: 54, Issue:5

    Topics: Delirium; Dexmedetomidine; Humans; Hydrocortisone; Hypnotics and Sedatives; Intensive Care Units; Magnesium; Magnesium Sulfate; Serotonin

2022
Effect of intraoperative dexmedetomidine on long-term survival in older patients after major noncardiac surgery: 3-year follow-up of a randomized trial.
    Journal of clinical anesthesia, 2023, Volume: 86

    Topics: Aged; China; Delirium; Dexmedetomidine; Female; Follow-Up Studies; Humans; Male

2023
A randomised controlled trial of dexmedetomidine for delirium in adults undergoing heart valve surgery.
    Anaesthesia, 2023, Volume: 78, Issue:5

    Topics: Adult; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Double-Blind Method; Heart Valves; Humans; Incidence

2023
In a secondary analysis from a randomised, double-blind placebo-controlled trial Dexmedetomidine blocks cholinergic dysregulation in delirium pathogenesis in patients with major surgery.
    Scientific reports, 2023, 03-09, Volume: 13, Issue:1

    Topics: Acetylcholinesterase; Butyrylcholinesterase; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans

2023
Effect of Different Administration Routes of Dexmedetomidine on Postoperative Delirium in Elderly Patients Undergoing Elective Spinal Surgery: A Prospective Randomized Double-Blinded Controlled Trial.
    Anesthesia and analgesia, 2023, 06-01, Volume: 136, Issue:6

    Topics: Aged; Anesthesia, General; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Pain; Prospective Studies

2023
Dexmedetomidine administration during brain tumour resection and postoperative delirium: a randomised controlled trial. Comment on Br J Anaesth 2023; 130: e307-e316.
    British journal of anaesthesia, 2023, Volume: 131, Issue:1

    Topics: Brain Neoplasms; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Hypnotics and Sedatives

2023
Association Between Postoperative Delirium and Long-Term Subjective Cognitive Decline in Older Patients Undergoing Cardiac Surgery: A Secondary Analysis of the Minimizing Intensive Care Unit Neurological Dysfunction with Dexmedetomidine-Induced Sleep Tria
    Journal of cardiothoracic and vascular anesthesia, 2023, Volume: 37, Issue:9

    Topics: Aged; Cardiac Surgical Procedures; Cognitive Dysfunction; Delirium; Dexmedetomidine; Emergence Delirium; Humans; Intensive Care Units; Postoperative Complications; Sleep

2023
Dexmedetomidine versus haloperidol for sedation of non-intubated patients with hyperactive delirium during the night in a high dependency unit: study protocol for an open-label, parallel-group, randomized controlled trial (DEX-HD trial).
    BMC anesthesiology, 2023, 06-03, Volume: 23, Issue:1

    Topics: Critical Illness; Delirium; Dexmedetomidine; Drugs, Investigational; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Psychomotor Agitation; Randomized Controlled Trials as Topic

2023
Dexmedetomidine vs. propofol sedation reduces the duration of mechanical ventilation after cardiac surgery - a randomized controlled trial.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:16

    Topics: Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Propofol; Respiration, Artificial

2023
A randomized control trial comparing prophylactic dexmedetomidine versus clonidine on rates and duration of delirium in older adult patients undergoing coronary artery bypass grafting.
    Journal of clinical anesthesia, 2020, Volume: 61

    Topics: Aged; Clonidine; Coronary Artery Bypass; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Middle Aged

2020
Preventive effect of dexmedetomidine on postictal delirium after electroconvulsive therapy: A randomised controlled study.
    European journal of anaesthesiology, 2020, Volume: 37, Issue:1

    Topics: Adolescent; Adult; Delirium; Dexmedetomidine; Double-Blind Method; Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Incidence; Male; Mental Disorders; Prospective Studies; Seizures; Treatment Outcome; Young Adult

2020
Impact of postoperative dexmedetomidine infusion on incidence of delirium in elderly patients undergoing major elective noncardiac surgery: a randomized clinical trial.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Aged; Delirium; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Hypnotics and Sedatives; Incidence; Infusions, Intravenous; Intensive Care Units; Male; Pain Measurement; Pain, Postoperative; Postoperative Complications

2019
Randomized clinical trial of intraoperative dexmedetomidine to prevent delirium in the elderly undergoing major non-cardiac surgery.
    The British journal of surgery, 2020, Volume: 107, Issue:2

    Topics: Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Intraoperative Care; Male; Perioperative Care

2020
Perioperative Dexmedetomidine Supplement Decreases Delirium Incidence After Adult Cardiac Surgery: A Randomized, Double-Blind, Controlled Study.
    Journal of cardiothoracic and vascular anesthesia, 2021, Volume: 35, Issue:2

    Topics: Adult; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Incidence

2021
Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery.
    BioMed research international, 2020, Volume: 2020

    Topics: Aged; Bradycardia; Conscious Sedation; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypotension; Incidence; Intensive Care Units; Length of Stay; Male; Midazolam; Middle Aged; Pain Measurement; Prospective Studies; Respiratory Insufficiency; Surgery, Oral

2020
Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery.
    Bioscience reports, 2020, 05-29, Volume: 40, Issue:5

    Topics: Administration, Intravenous; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; China; Cytokines; Delirium; Dexmedetomidine; Double-Blind Method; Esophageal Neoplasms; Esophagectomy; Female; Health Status; Humans; Inflammation; Inflammation Mediators; Laparoscopy; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Sufentanil; Thoracoscopy; Time Factors; Treatment Outcome

2020
Effect of intraoperative dexmedetomidine infusion on delirium in adult patients following cardiac valve surgery: a protocol of a randomized, double-blinded, and placebo-controlled study.
    Trials, 2020, Jul-14, Volume: 21, Issue:1

    Topics: Adult; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Double-Blind Method; Heart Valves; Humans; Neuroprotective Agents; Prospective Studies; Randomized Controlled Trials as Topic; Reproducibility of Results; Stroke Volume; Ventricular Function, Left

2020
Dexmedetomidine for reduction of atrial fibrillation and delirium after cardiac surgery (DECADE): a randomised placebo-controlled trial.
    Lancet (London, England), 2020, 07-18, Volume: 396, Issue:10245

    Topics: Atrial Fibrillation; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Postoperative Complications; Treatment Outcome

2020
Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia: A double-blind, randomised clinical trial.
    European journal of anaesthesiology, 2021, Mar-01, Volume: 38, Issue:Suppl 1

    Topics: Aged; Anesthesia, Intravenous; Delirium; Dexmedetomidine; Double-Blind Method; Esophagectomy; Humans; Hypnotics and Sedatives

2021
Dexmedetomidine for the prevention of postoperative delirium in patients after intracranial operation for brain tumours (DEPOD study): a study protocol and statistical plan for a multicentre randomised controlled trial.
    BMJ open, 2020, 11-23, Volume: 10, Issue:11

    Topics: Adrenergic alpha-2 Receptor Agonists; Brain Neoplasms; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Randomized Controlled Trials as Topic

2020
Propofol plus low-dose dexmedetomidine infusion and postoperative delirium in older patients undergoing cardiac surgery.
    British journal of anaesthesia, 2021, Volume: 126, Issue:3

    Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Postoperative Complications; Propofol; Treatment Outcome

2021
Dexmedetomidine for hyperactive delirium at the end of life: An open-label single arm pilot study with dose escalation in adult patients admitted to an inpatient palliative care unit.
    Palliative medicine, 2021, Volume: 35, Issue:4

    Topics: Adult; Death; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Inpatients; Intensive Care Units; Palliative Care; Pilot Projects; Prospective Studies

2021
Cognitive Outcomes after DEXmedetomidine sedation in cardiac surgery: CODEX randomised controlled trial protocol.
    BMJ open, 2021, 04-13, Volume: 11, Issue:4

    Topics: Anesthesia, General; Cardiac Surgical Procedures; Cognition; Delirium; Dexmedetomidine; Humans; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

2021
The Effectiveness of Dexmedetomidine as a Prophylactic Treatment for Emergence Delirium Among Combat Veterans With High Anxiety: A Randomized Placebo-Controlled Trial.
    Military medicine, 2023, 01-04, Volume: 188, Issue:1-2

    Topics: Anesthesia, General; Anesthetics; Anxiety; Child; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Humans; Prospective Studies; Veterans

2023
Neuroprotective effects of intraoperative dexmedetomidine versus saline infusion combined with goal-directed haemodynamic therapy for patients undergoing cranial surgery: A randomised controlled trial.
    European journal of anaesthesiology, 2021, 12-01, Volume: 38, Issue:12

    Topics: Adult; Delirium; Dexmedetomidine; Double-Blind Method; Goals; Hemodynamics; Humans; Neuroprotective Agents

2021
Association of Pain With Atrial Fibrillation and Delirium After Cardiac Surgery: A DECADE Sub-Study.
    Journal of cardiothoracic and vascular anesthesia, 2021, Volume: 35, Issue:10

    Topics: Adult; Atrial Fibrillation; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Pain, Postoperative

2021
Dexmedetomidine Effect on Emergence Agitation and Delirium in Children Undergoing Laparoscopic Hernia Repair: a Preliminary Study.
    The Journal of international medical research, 2017, Volume: 45, Issue:3

    Topics: Child, Preschool; Delirium; Dexmedetomidine; Female; Herniorrhaphy; Humans; Laparoscopy; Male; Psychomotor Agitation

2017
A Pilot Study of the Use of Dexmedetomidine for the Control of Delirium by Reducing the Serum Concentrations of Brain-Derived Neurotrophic Factor, Neuron-Specific Enolase, and S100B in Polytrauma Patients.
    Journal of intensive care medicine, 2019, Volume: 34, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Brain-Derived Neurotrophic Factor; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Kaplan-Meier Estimate; Male; Middle Aged; Multiple Trauma; Phosphopyruvate Hydratase; Pilot Projects; Prospective Studies; S100 Calcium Binding Protein beta Subunit; Treatment Outcome; Young Adult

2019
Intraoperative Infusion of Dexmedetomidine for Prevention of Postoperative Delirium and Cognitive Dysfunction in Elderly Patients Undergoing Major Elective Noncardiac Surgery: A Randomized Clinical Trial.
    JAMA surgery, 2017, Aug-16, Volume: 152, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Cognitive Dysfunction; Delirium; Dexmedetomidine; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Infusions, Intravenous; Intraoperative Care; Male; Postoperative Complications; Treatment Failure

2017
Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial.
    BMJ open, 2017, Jul-13, Volume: 7, Issue:7

    Topics: Critical Illness; Delirium; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Length of Stay; Propofol; Quality of Life; Research Design; Sleep; Switzerland; Time Factors

2017
Development and validation of risk-stratification delirium prediction model for critically ill patients: A prospective, observational, single-center study.
    Medicine, 2017, Volume: 96, Issue:29

    Topics: Academic Medical Centers; Age Factors; APACHE; Area Under Curve; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Incidence; Logistic Models; Male; Middle Aged; Models, Biological; Multivariate Analysis; Prognosis; Prospective Studies; Respiration, Artificial; Risk; ROC Curve

2017
Sedative Plasma Concentrations and Delirium Risk in Critical Illness.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:6

    Topics: Aged; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Logistic Models; Lorazepam; Male; Middle Aged; Respiration, Artificial

2018
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
    American journal of respiratory and critical care medicine, 2018, 05-01, Volume: 197, Issue:9

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Night Care; Placebo Effect; Propofol; Time Factors

2018
Intraoperative Sedation With Dexmedetomidine is Superior to Propofol for Elderly Patients Undergoing Hip Arthroplasty: A Prospective Randomized Controlled Study.
    The Clinical journal of pain, 2018, Volume: 34, Issue:9

    Topics: Aged; Arthroplasty, Replacement, Hip; Cognitive Dysfunction; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Incidence; Male; Nerve Block; Postoperative Complications; Propofol; Treatment Outcome

2018
Minimizing ICU Neurological Dysfunction with Dexmedetomidine-induced Sleep (MINDDS): protocol for a randomised, double-blind, parallel-arm, placebo-controlled trial.
    BMJ open, 2018, 04-20, Volume: 8, Issue:4

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Cardiac Procedures; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Intensive Care Units; Sleep; Sleep Wake Disorders; Systemic Inflammatory Response Syndrome

2018
Impact of dexmedetomidine infusion during general anaesthesia on incidence of postoperative delirium in elderly patients after major non-cardiac surgery: study protocol of a randomised, double-blinded and placebo-controlled trial.
    BMJ open, 2018, 04-21, Volume: 8, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia, General; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Incidence; Male; Middle Aged; Pain, Postoperative; Postoperative Complications

2018
Effects of dexmedetomidine on delirium duration of non-intubated ICU patients (4D trial): study protocol for a randomized trial.
    Trials, 2018, Jun-04, Volume: 19, Issue:1

    Topics: Delirium; Dexmedetomidine; Double-Blind Method; France; Humans; Hypnotics and Sedatives; Intensive Care Units; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome

2018
Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial.
    Trials, 2018, Jun-22, Volume: 19, Issue:1

    Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Boston; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Cognition; Coronary Artery Bypass; Delirium; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Heart Valve Prosthesis Implantation; Humans; Hypnotics and Sedatives; Length of Stay; Propofol; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Time Factors; Treatment Outcome

2018
Effect of Intravenous Acetaminophen vs Placebo Combined With Propofol or Dexmedetomidine on Postoperative Delirium Among Older Patients Following Cardiac Surgery: The DEXACET Randomized Clinical Trial.
    JAMA, 2019, 02-19, Volume: 321, Issue:7

    Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Incidence; Length of Stay; Male; Middle Aged; Postoperative Complications; Propofol

2019
Effect of perioperative administration of dexmedetomidine on delirium after cardiac surgery in elderly patients: a double-blinded, multi-center, randomized study.
    Clinical interventions in aging, 2019, Volume: 14

    Topics: Aged; Analgesics; Analgesics, Opioid; Anesthesia, General; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Postoperative Period; Propofol; Time Factors

2019
Pain, fentanyl consumption, and delirium in adolescents after scoliosis surgery: dexmedetomidine vs midazolam.
    Paediatric anaesthesia, 2013, Volume: 23, Issue:5

    Topics: Adolescent; Analgesics, Opioid; Anesthesia, General; Arterial Pressure; Child; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Female; Fentanyl; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Orthopedic Procedures; Pain Management; Pain Measurement; Pain, Postoperative; Prospective Studies; Psychomotor Agitation; Scoliosis

2013
Perioperative dexmedetomidine improves outcomes of cardiac surgery.
    Circulation, 2013, Apr-16, Volume: 127, Issue:15

    Topics: Acute Kidney Injury; Adrenergic alpha-2 Receptor Agonists; Aged; Cardiac Surgical Procedures; Catecholamines; Delirium; Dexmedetomidine; Female; Heart Diseases; Hospital Mortality; Hospital Records; Humans; Hypnotics and Sedatives; Length of Stay; Male; Middle Aged; Myocardial Ischemia; Patient Readmission; Perioperative Care; Postoperative Complications; Respiration, Artificial; Retrospective Studies; Sepsis; Stroke; Treatment Outcome

2013
Early goal-directed sedation versus standard sedation in mechanically ventilated critically ill patients: a pilot study*.
    Critical care medicine, 2013, Volume: 41, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Airway Extubation; Algorithms; APACHE; Benzodiazepines; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Drug Utilization; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pilot Projects; Propofol; Prospective Studies; Respiration, Artificial; Restraint, Physical

2013
A comparison of single-dose dexmedetomidine or propofol on the incidence of emergence delirium in children undergoing general anaesthesia for magnetic resonance imaging.
    Anaesthesia, 2015, Volume: 70, Issue:4

    Topics: Anesthesia Recovery Period; Anesthesia, General; Child; Child, Preschool; Delirium; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Magnetic Resonance Imaging; Male; Propofol; Time Factors

2015
Intranasal dexmedetomidine premedication reduces minimum alveolar concentration of sevoflurane for laryngeal mask airway insertion and emergence delirium in children: a prospective, randomized, double-blind, placebo-controlled trial.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:5

    Topics: Administration, Intranasal; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Dexmedetomidine; Double-Blind Method; Drug Synergism; Female; Humans; Hypnotics and Sedatives; Laryngeal Masks; Male; Methyl Ethers; Premedication; Prospective Studies; Sevoflurane; Treatment Outcome

2015
[Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation].
    Zhonghua yi xue za zhi, 2014, Nov-11, Volume: 94, Issue:41

    Topics: Aged; Analgesics; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Postoperative Care; Postoperative Period; Propofol; Respiration, Artificial; Time Factors

2014
[Preventive effect of dexmedetomidine on postoperative delirium in elderly patients with oral cancer].
    Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2015, Volume: 24, Issue:2

    Topics: Aged; Anesthesia, General; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Mouth Neoplasms; Postoperative Complications; Psychomotor Agitation

2015
Effect of dexmedetomidine on preventing agitation and delirium after microvascular free flap surgery: a randomized, double-blind, control study.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2015, Volume: 73, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia Recovery Period; Blood Pressure; Delirium; Dexmedetomidine; Double-Blind Method; Female; Follow-Up Studies; Free Tissue Flaps; Heart Rate; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Pain, Postoperative; Placebos; Plastic Surgery Procedures; Postoperative Nausea and Vomiting; Preanesthetic Medication; Prospective Studies; Psychomotor Agitation; Sleep; Sufentanil

2015
[New approach to postoperative delirium treatment].
    Khirurgiia, 2015, Issue:3

    Topics: Abdominal Cavity; Adult; Aged; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Postoperative Complications; Surgical Procedures, Operative; Treatment Outcome

2015
A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children.
    Anaesthesia, 2016, Volume: 71, Issue:1

    Topics: Anesthetics, Inhalation; Child; Child, Preschool; Delirium; Desflurane; Dexmedetomidine; Female; Humans; Isoflurane; Male; Propofol

2016
Dexmedetomidine reduces postoperative delirium after joint replacement in elderly patients with mild cognitive impairment.
    Aging clinical and experimental research, 2016, Volume: 28, Issue:4

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement; Cognitive Dysfunction; Delirium; Dexmedetomidine; Female; Humans; Male; Postoperative Complications; Prospective Studies

2016
Dexmedetomidine versus Propofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial.
    Anesthesiology, 2016, Volume: 124, Issue:2

    Topics: Aged; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Postoperative Complications; Propofol; Prospective Studies; Single-Blind Method

2016
[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:1

    Topics: Analgesics; Circadian Rhythm; Critical Care; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Propofol; Prospective Studies; Respiration, Artificial

2016
Dexmedetomidine for the Treatment of Hyperactive Delirium Refractory to Haloperidol in Nonintubated ICU Patients: A Nonrandomized Controlled Trial.
    Critical care medicine, 2016, Volume: 44, Issue:7

    Topics: Aged; Antipsychotic Agents; Cost-Benefit Analysis; Delirium; Dexmedetomidine; Drug Costs; Drug Resistance; Female; Haloperidol; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Length of Stay; Middle Aged; Psychomotor Agitation; Risk Factors

2016
Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium: A Randomized Clinical Trial.
    JAMA, 2016, Apr-12, Volume: 315, Issue:14

    Topics: Aged; Australia; Contraindications; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; New Zealand; Proportional Hazards Models; Psychomotor Agitation; Respiration, Artificial; Time Factors; Treatment Outcome; Ventilator Weaning

2016
[A study of using dexmedetomidine in ventilator bundle treatment in an ICU].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:10

    Topics: Arterial Pressure; Blood Pressure; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Midazolam; Pain; Prospective Studies; Respiration, Artificial; Single-Blind Method

2015
[The influence of the sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients].
    Zhonghua wei zhong bing ji jiu yi xue, 2015, Volume: 27, Issue:10

    Topics: Analgesia; Arterial Pressure; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Midazolam; Pain; Piperidines; Prospective Studies; Remifentanil; Respiration, Artificial

2015
Clinical study of midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in intensive care unit.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2016, Apr-01, Volume: 19, Issue:2

    Topics: Adult; Aged; Critical Care; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Midazolam; Middle Aged; Prognosis; Prospective Studies; Respiration, Artificial; Risk Assessment; Statistics, Nonparametric; Treatment Outcome; Ventilator Weaning

2016
The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients.
    Journal of cardiothoracic and vascular anesthesia, 2016, Volume: 30, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Cardiac Surgical Procedures; Coronary Artery Bypass; Delirium; Dexmedetomidine; Female; Heart Valves; Hospital Mortality; Humans; Infusions, Intravenous; Male; Middle Aged; Perioperative Care; Retrospective Studies; Stroke; Treatment Outcome

2016
Dexmedetomidine for prevention of delirium in elderly patients after non-cardiac surgery: a randomised, double-blind, placebo-controlled trial.
    Lancet (London, England), 2016, Oct-15, Volume: 388, Issue:10054

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Analgesics, Non-Narcotic; China; Confusion; Critical Care; Delirium; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Evidence-Based Medicine; Female; Humans; Incidence; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Primary Prevention; Respiration, Artificial; Surgical Procedures, Operative; Time Factors; Treatment Outcome

2016
Effects of intraoperative dexmedetomidine with intravenous anesthesia on postoperative emergence agitation/delirium in pediatric patients undergoing tonsillectomy with or without adenoidectomy: A CONSORT-prospective, randomized, controlled clinical trial.
    Medicine, 2016, Volume: 95, Issue:49

    Topics: Adenoidectomy; Anesthesia, Intravenous; Child; Child, Preschool; Delirium; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Intraoperative Care; Male; Postoperative Complications; Prospective Studies; Reference Values; Statistics, Nonparametric; Tonsillectomy; Treatment Outcome

2016
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.
    JAMA, 2009, Feb-04, Volume: 301, Issue:5

    Topics: Adrenergic alpha-Agonists; Aged; APACHE; Conscious Sedation; Critical Illness; Delirium; Dexmedetomidine; Double-Blind Method; Female; GABA Modulators; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Length of Stay; Male; Midazolam; Middle Aged; Prospective Studies; Respiration, Artificial

2009
Dexmedetomidine vs. haloperidol in delirious, agitated, intubated patients: a randomised open-label trial.
    Critical care (London, England), 2009, Volume: 13, Issue:3

    Topics: Adult; Aged; Delirium; Dexmedetomidine; Dopamine Antagonists; Drug-Related Side Effects and Adverse Reactions; Female; Haloperidol; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Male; Middle Aged; Pilot Projects; Psychomotor Agitation; Respiration, Artificial

2009
Prevalence of delirium with dexmedetomidine compared with morphine based therapy after cardiac surgery: a randomized controlled trial (DEXmedetomidine COmpared to Morphine-DEXCOM Study).
    Anesthesiology, 2009, Volume: 111, Issue:5

    Topics: Adrenergic alpha-Agonists; Aged; Analgesics, Opioid; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Intra-Aortic Balloon Pumping; Male; Morphine; Pain, Postoperative; Postoperative Care; Propofol

2009
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
    Critical care (London, England), 2010, Volume: 14, Issue:2

    Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Male; Middle Aged; Outcome Assessment, Health Care; Respiration, Artificial; Sepsis

2010
Dexmedetomidine as a pediatric anesthetic premedication to reduce anxiety and to deter emergence delirium.
    AANA journal, 2011, Volume: 79, Issue:3

    Topics: Anxiety; Child; Child, Preschool; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant; Male; Nurse Anesthetists; Postoperative Complications; Prospective Studies

2011
Does dexmedetomidine prevent emergence delirium in children after sevoflurane-based general anesthesia?
    Paediatric anaesthesia, 2005, Volume: 15, Issue:12

    Topics: Adrenergic alpha-Agonists; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child, Preschool; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Methyl Ethers; Postoperative Complications; Prospective Studies; Sevoflurane

2005
Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery.
    Paediatric anaesthesia, 2006, Volume: 16, Issue:7

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Child; Child, Preschool; Delirium; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Magnetic Resonance Imaging; Male; Methyl Ethers; Oxygen Consumption; Postoperative Complications; Postoperative Nausea and Vomiting; Psychomotor Agitation; Sevoflurane

2006
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
    JAMA, 2007, Dec-12, Volume: 298, Issue:22

    Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Male; Middle Aged; Neuropsychological Tests; Respiration, Artificial

2007

Other Studies

105 other study(ies) available for dexmedetomidine and Delirium

ArticleYear
Comment on: Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis.
    Journal of clinical anesthesia, 2021, Volume: 75

    Topics: Adult; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives

2021
Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes.
    Journal of intensive care medicine, 2022, Volume: 37, Issue:10

    Topics: Benzodiazepines; Child; Child, Preschool; Critical Illness; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Intensive Care Units, Pediatric; Length of Stay; Respiration, Artificial; Retrospective Studies; Risk Factors

2022
Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia.
    European journal of anaesthesiology, 2022, 02-01, Volume: 39, Issue:2

    Topics: Aged; Anesthesia, General; Anesthesia, Intravenous; Delirium; Dexmedetomidine; Esophagectomy; Humans

2022
Dexmedetomidine effect on delirium in elderly patients undergoing general anesthesia: A protocol for systematic review and meta-analysis.
    Medicine, 2021, Dec-03, Volume: 100, Issue:48

    Topics: Aged; Anesthesia, General; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Meta-Analysis as Topic; Systematic Reviews as Topic

2021
Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia.
    European journal of anaesthesiology, 2022, 03-01, Volume: 39, Issue:3

    Topics: Aged; Anesthesia, General; Anesthesia, Intravenous; Delirium; Dexmedetomidine; Esophagectomy; Humans

2022
Effects of dexmedetomidine on surgery for type A acute aortic dissection outcome.
    Scientific reports, 2022, 02-17, Volume: 12, Issue:1

    Topics: Acute Kidney Injury; Aged; Aortic Dissection; Atrial Fibrillation; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Hospital Mortality; Humans; Male; Middle Aged; Postoperative Complications; Retrospective Studies; Taiwan

2022
The Preventive Effect of Dexmedetomidine Against Delirium in Patients with Aortic Dissection: A Retrospective Cohort Study.
    The heart surgery forum, 2022, Jul-07, Volume: 25, Issue:4

    Topics: Aortic Dissection; Critical Care; Delirium; Dexmedetomidine; Humans; Retrospective Studies

2022
Monitoring of nighttime EEG slow-wave activity during dexmedetomidine infusion in patients with hyperactive ICU delirium: An observational pilot study.
    Acta anaesthesiologica Scandinavica, 2022, Volume: 66, Issue:10

    Topics: Delirium; Dexmedetomidine; Electroencephalography; Humans; Intensive Care Units; Pilot Projects; Sleep

2022
Anti-Inflammatory Action of Dexmedetomidine on Human Microglial Cells.
    International journal of molecular sciences, 2022, Sep-03, Volume: 23, Issue:17

    Topics: Anti-Inflammatory Agents; Cytokines; Delirium; Dexmedetomidine; Humans; I-kappa B Proteins; Interleukin-6; Interleukin-8; Lipopolysaccharides; Microglia; NF-kappa B; p38 Mitogen-Activated Protein Kinases

2022
Pediatric delirium is associated with increased brain injury marker levels in cardiac surgery patients.
    Scientific reports, 2022, 11-04, Volume: 12, Issue:1

    Topics: Adult; Bayes Theorem; Biomarkers; Brain Injuries; Cardiac Surgical Procedures; Child; Coma; Delirium; Dexmedetomidine; Humans; Infant; Infant, Newborn; Intensive Care Units; Midazolam; Prospective Studies

2022
Evaluation of Dexmedetomidine as an Adjunct to Phenobarbital for Alcohol Withdrawal in Critically Ill Patients.
    Journal of intensive care medicine, 2023, Volume: 38, Issue:6

    Topics: Adult; Alcoholism; Benzodiazepines; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Phenobarbital; Retrospective Studies; Substance Withdrawal Syndrome

2023
Shortages of agents used to treat antimuscarinic delirium.
    The American journal of emergency medicine, 2023, Volume: 67

    Topics: Acetylcholinesterase; Benzodiazepines; Delirium; Dexmedetomidine; Drugs, Generic; Humans; Muscarinic Antagonists; Rivastigmine

2023
The impact of dexmedetomidine on postoperative delirium: should we throw out a DECADE of research?
    British journal of anaesthesia, 2023, Volume: 130, Issue:6

    Topics: Delirium; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Postoperative Complications

2023
Automated phenotyping of postoperative delirium-like behaviour in mice reveals the therapeutic efficacy of dexmedetomidine.
    Communications biology, 2023, 08-02, Volume: 6, Issue:1

    Topics: Animals; Behavior, Animal; Delirium; Dexmedetomidine; Emergence Delirium; Mice; Postoperative Complications

2023
[Postoperative Delirium in Patients on Cardiopulmonary Bypass for Cardiovascular Surgeries: Incidence and Influencing Factors].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2023, Volume: 54, Issue:4

    Topics: Blood Glucose; Cardiopulmonary Bypass; Delirium; Dexmedetomidine; Emergence Delirium; Etomidate; Humans; Incidence; Postoperative Complications; Prospective Studies; Risk Factors

2023
Sedatives and Postoperative Delirium: Comment.
    Anesthesiology, 2023, 11-01, Volume: 139, Issue:5

    Topics: Delirium; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Postoperative Complications

2023
Dexmedetomidine use for patients in palliative care with intractable pain and delirium: A retrospective study.
    PloS one, 2023, Volume: 18, Issue:9

    Topics: Adolescent; Adult; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain, Intractable; Palliative Care; Retrospective Studies

2023
Dexmedetomidine: A Novel Strategy for Patients with Intractable Pain, Opioid-Induced Hyperalgesia, or Delirium at the End of Life.
    Journal of palliative medicine, 2020, Volume: 23, Issue:11

    Topics: Analgesics, Opioid; Death; Delirium; Dexmedetomidine; Humans; Hyperalgesia; Hypnotics and Sedatives; Intensive Care Units; Pain, Intractable

2020
Sedation selection to reduce delirium risk: Why dexmedetomidine may be a better choice.
    Journal of the American Association of Nurse Practitioners, 2020, Jan-16, Volume: 33, Issue:4

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol

2020
Valproic Acid for the Management of Agitation and Delirium in the Intensive Care Setting: A Retrospective Analysis.
    Clinical therapeutics, 2020, Volume: 42, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antipsychotic Agents; Benzodiazepines; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Psychomotor Agitation; Retrospective Studies; Valproic Acid

2020
Use of intraoperative dexmedetomidine to prevent postoperative delirium in elderly patients.
    The British journal of surgery, 2020, Volume: 107, Issue:7

    Topics: Aged; Anesthesia, General; Delirium; Dexmedetomidine; Humans

2020
Author response: Postoperative delirium in elderly patients: diagnosis and risk factors.
    The British journal of surgery, 2020, Volume: 107, Issue:7

    Topics: Aged; Delirium; Dexmedetomidine; Humans; Risk Factors

2020
The evolving clinical use of dexmedetomidine.
    Lancet (London, England), 2020, 07-18, Volume: 396, Issue:10245

    Topics: Atrial Fibrillation; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives

2020
Effectiveness of Quetiapine as a Sedative Adjunct in Mechanically Ventilated Adults Without Delirium.
    The Annals of pharmacotherapy, 2021, Volume: 55, Issue:2

    Topics: Adjuvants, Pharmaceutic; Adult; Analgesics, Opioid; Benzodiazepines; Cohort Studies; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pain; Propofol; Quetiapine Fumarate; Respiration, Artificial; Retrospective Studies

2021
Could COVID delirium bring on dementia?
    Nature, 2020, Volume: 588, Issue:7836

    Topics: Cognitive Dysfunction; COVID-19; Critical Illness; Delirium; Dementia; Dexmedetomidine; Follow-Up Studies; Humans

2020
Intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment.
    International journal of geriatric psychiatry, 2021, Volume: 36, Issue:1

    Topics: Aged; Anesthesia, General; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Postoperative Complications

2021
Dexmedetomidine for the treatment of delirium in the intensive care unit: do we need more evidence for adult and pediatric patients?
    Minerva anestesiologica, 2021, Volume: 87, Issue:1

    Topics: Adult; Child; Critical Illness; Delirium; Dexmedetomidine; Humans; Intensive Care Units

2021
Dexmedetomidine is associated with intraoperative hypotension and may bring poor postoperative outcomes.
    International journal of geriatric psychiatry, 2021, Volume: 36, Issue:9

    Topics: Delirium; Dexmedetomidine; Humans; Hypotension

2021
Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database.
    The Annals of thoracic surgery, 2021, Volume: 112, Issue:6

    Topics: Analgesics, Non-Narcotic; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Incidence; Pain, Postoperative; Postoperative Complications; Propensity Score; Retrospective Studies; Societies, Medical; Thoracic Surgery; United States

2021
Are dexmedetomidine and olanzapine suitable to control delirium in critically ill elderly patients? A retrospective cohort study.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 139

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cohort Studies; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Length of Stay; Male; Olanzapine; Prognosis; Retrospective Studies; Risk Factors

2021
The effect of a dexmedetomidine infusion on delirium in the ICU.
    Journal of clinical anesthesia, 2022, Volume: 79

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units

2022
In reference to intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment.
    International journal of geriatric psychiatry, 2021, Volume: 36, Issue:10

    Topics: Aged; Cognitive Dysfunction; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives

2021
Comment on: "Perioperative dexmedetomidine administration to prevent delirium in adults after non-cardiac surgery: A systematic review and meta-analysis".
    Journal of clinical anesthesia, 2021, Volume: 74

    Topics: Adult; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives

2021
Current Evidence Demonstrates a Significant Reduction in the Incidence of Delirium With Postoperative Dexmedetomidine Versus Propofol Sedation.
    Journal of cardiothoracic and vascular anesthesia, 2022, Volume: 36, Issue:1

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Incidence; Propofol

2022
Dexmedetomidine versus Propofol Sedation for Prevention of Postoperative Delirium: Clarifications Required [Letter].
    Clinical interventions in aging, 2021, Volume: 16

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol

2021
Perioperative dexmedetomidine and 5-year survival in patients undergoing cardiac surgery. Reply to Br J Anaesth 2021; 127: e127-8.
    British journal of anaesthesia, 2021, Volume: 127, Issue:5

    Topics: Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans

2021
A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China.
    Chinese medical journal, 2017, May-20, Volume: 130, Issue:10

    Topics: Delirium; Dexmedetomidine; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Pain; Pain Management; Pain Measurement; Surveys and Questionnaires

2017
Confusion Regarding Surgical Delirium-Is Dexmedetomidine the Answer?
    JAMA surgery, 2017, 08-16, Volume: 152, Issue:8

    Topics: Aged; Cognitive Dysfunction; Delirium; Dexmedetomidine; Elective Surgical Procedures; Humans

2017
[The impact of goal directed analgesia on mechanical ventilated patients's outcomes in intensive care unit: a clinical observational study].
    Zhonghua nei ke za zhi, 2017, Nov-01, Volume: 56, Issue:11

    Topics: Analgesia; China; Critical Care; Delirium; Dexmedetomidine; Drug Administration Schedule; Goals; Humans; Hypnotics and Sedatives; Incidence; Intensive Care Units; Length of Stay; Methohexital; Midazolam; Outcome and Process Assessment, Health Care; Pain; Psychomotor Agitation; Respiration, Artificial; Ventilators, Mechanical

2017
Delirium and effect of circadian light in the intensive care unit: a retrospective cohort study.
    Acta anaesthesiologica Scandinavica, 2018, Volume: 62, Issue:3

    Topics: Aged; Aged, 80 and over; Circadian Rhythm; Confusion; Delirium; Dexmedetomidine; Female; Humans; Incidence; Intensive Care Units; Logistic Models; Male; Middle Aged; Phototherapy; Retrospective Studies; Risk Factors

2018
Use of dexmedetomidine in a cardiac intensive care unit.
    Journal of clinical anesthesia, 2018, Volume: 44

    Topics: Aged; Aged, 80 and over; Critical Care; Delirium; Dexmedetomidine; Drug Utilization; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pain; Prospective Studies; Psychomotor Agitation

2018
Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Units.
    BioMed research international, 2017, Volume: 2017

    Topics: Adult; Aged; Anesthesia; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Respiration, Artificial; Risk Factors

2017
[DEXMEDETOMIDINE SEDATION DURING TRANSCATHETER AORTIC VALVE IMPLANTATION.]
    Anesteziologiia i reanimatologiia, 2016, Volume: 61, Issue:4

    Topics: Aged; Anesthesia, Conduction; Aortic Valve Stenosis; Conscious Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Transcatheter Aortic Valve Replacement; Treatment Outcome

2016
Effect of Sedation Regimen on Weaning from Mechanical Ventilation in the Intensive Care Unit.
    Clinical drug investigation, 2018, Volume: 38, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anxiety; Critical Care; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pain; Propofol; Quality of Life; Respiration, Artificial; Retrospective Studies; Stress Disorders, Post-Traumatic; Sweden; Ventilator Weaning; Young Adult

2018
The Sandman in the ICU: A Novel Use of Dexmedetomidine?
    American journal of respiratory and critical care medicine, 2018, 05-01, Volume: 197, Issue:9

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units

2018
Dexmedetomidine-induced fever and delirium: A case report.
    Journal of clinical pharmacy and therapeutics, 2018, Volume: 43, Issue:3

    Topics: Adult; Delirium; Dexmedetomidine; Female; Fever; Humans; Hypnotics and Sedatives; Intensive Care Units; Respiratory Distress Syndrome

2018
Comparison of Ketamine- Versus Nonketamine-Based Sedation on Delirium and Coma in the Intensive Care Unit.
    Journal of intensive care medicine, 2020, Volume: 35, Issue:6

    Topics: Academic Medical Centers; Aged; Coma; Critical Care Outcomes; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Ketamine; Male; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies; United States

2020
Cycling of Dexmedetomidine May Prevent Delirium After Liver Transplantation.
    Transplantation proceedings, 2018, Volume: 50, Issue:4

    Topics: Aged; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Liver Transplantation; Male; Middle Aged; Retrospective Studies

2018
Impact of Dexmedetomidine on Long-term Outcomes After Noncardiac Surgery in Elderly: 3-Year Follow-up of a Randomized Controlled Trial.
    Annals of surgery, 2019, Volume: 270, Issue:2

    Topics: Aged; Analgesics, Non-Narcotic; Cognition; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Male; Pain, Postoperative; Postoperative Care; Quality of Life; Retrospective Studies; Surgical Procedures, Operative; Time Factors; Treatment Outcome

2019
Reply to Thille et al.: Are Sleep Alterations the Cause of ICU Delirium?
    American journal of respiratory and critical care medicine, 2018, 09-01, Volume: 198, Issue:5

    Topics: Delirium; Dexmedetomidine; Humans; Intensive Care Units; Sleep

2018
Are Sleep Alterations the Cause of ICU Delirium?
    American journal of respiratory and critical care medicine, 2018, 09-01, Volume: 198, Issue:5

    Topics: Delirium; Dexmedetomidine; Humans; Intensive Care Units; Sleep

2018
Depth of Propofol Sedation and Postoperative Delirium: The Jury Is Still Out.
    JAMA surgery, 2018, 11-01, Volume: 153, Issue:11

    Topics: Aged; Anesthesia; Delirium; Dexmedetomidine; Hip Fractures; Humans; Propofol

2018
Sepsis-associated encephalopathy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018, 09-10, Volume: 190, Issue:36

    Topics: Critical Care; Delirium; Dexmedetomidine; Guidelines as Topic; Humans; Hypnotics and Sedatives; Muscular Diseases; Neurocognitive Disorders; Organ Dysfunction Scores; Polyneuropathies; Sepsis-Associated Encephalopathy

2018
Be careful about heterogeneity and publication bias in meta-analysis.
    Journal of clinical anesthesia, 2019, Volume: 53

    Topics: Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Publication Bias; Randomized Controlled Trials as Topic

2019
Prolonged sedation in critically ill children: is dexmedetomidine a safe option for younger age? An off-label experience.
    Minerva anestesiologica, 2019, Volume: 85, Issue:2

    Topics: Child, Preschool; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Drug Interactions; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Off-Label Use; Retrospective Studies; Substance Withdrawal Syndrome

2019
Effect of dexmedetomidine on postoperative delirium in elderly patients undergoing hip fracture surgery.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:5(Special)

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Anesthesia, General; Delirium; Dexmedetomidine; Female; Hip Fractures; Humans; Hypnotics and Sedatives; Incidence; Male; Middle Aged; Neuroprotective Agents; Pain; Postoperative Complications; Propofol

2018
Effects of Dexmedetomidine Combined with Sufentanil on Postoperative Delirium in Young Patients After General Anesthesia.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Dec-10, Volume: 24

    Topics: Adult; Anesthesia, General; China; Delirium; Dexmedetomidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Interleukin-6; Male; Postoperative Complications; Sufentanil; Tumor Necrosis Factor-alpha; Young Adult

2018
Dexmedetomidine for the prevention of delirium in critically ill patients - A protocol for a systematic review.
    Acta anaesthesiologica Scandinavica, 2019, Volume: 63, Issue:4

    Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Research Design; Systematic Reviews as Topic

2019
Dexmedetomidine for the management of delirium in critically ill patients-A protocol for a systematic review.
    Acta anaesthesiologica Scandinavica, 2019, Volume: 63, Issue:4

    Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Research Design; Systematic Reviews as Topic

2019
Intraoperative dexmedetomidine to prevent postoperative delirium: in search of the magic bullet.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2019, Volume: 66, Issue:4

    Topics: Delirium; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Thoracic Surgery

2019
Effects of dexmedetomidine on delirium and mortality during sedation in ICU patients: a systematic review and meta-analysis protocol.
    BMJ open, 2019, 04-03, Volume: 9, Issue:4

    Topics: Conscious Sedation; Deep Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Meta-Analysis as Topic; Research Design; Systematic Reviews as Topic

2019
Perioperative Dexmedetomidine Reduces Delirium in Elderly Patients after Lung Cancer Surgery.
    Psychiatria Danubina, 2019, Volume: 31, Issue:1

    Topics: Aged; China; Delirium; Dexmedetomidine; Emergence Delirium; Humans; Hypnotics and Sedatives; Lung Neoplasms; Postoperative Complications; Retrospective Studies

2019
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
    Journal of critical care, 2019, Volume: 53

    Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzodiazepines; Critical Care; Cross-Sectional Studies; Deep Sedation; Delirium; Dexmedetomidine; Extracorporeal Membrane Oxygenation; Fentanyl; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pain; Perception; Professional Practice; Propofol; Psychomotor Agitation; Respiratory Insufficiency

2019
Intravenous Acetaminophen for Postoperative Delirium.
    JAMA, 2019, 07-16, Volume: 322, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Humans; Propofol

2019
Intravenous Acetaminophen for Postoperative Delirium-Reply.
    JAMA, 2019, 07-16, Volume: 322, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Humans; Propofol

2019
Perioperative dexmedetomidine improves mortality in patients undergoing coronary artery bypass surgery.
    Journal of cardiothoracic and vascular anesthesia, 2014, Volume: 28, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Cardiac Surgical Procedures; Cohort Studies; Coronary Artery Bypass; Delirium; Dexmedetomidine; Electrocardiography; Female; Hospital Mortality; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Length of Stay; Logistic Models; Male; Middle Aged; Odds Ratio; Postoperative Complications; Proportional Hazards Models; Retrospective Studies; Risk Factors; Survival Analysis; Treatment Outcome

2014
More questions than answers in ICU delirium: pressing issues for future research.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:11

    Topics: Antipsychotic Agents; Critical Care; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Practice Guidelines as Topic

2013
[Three successful cases of continuous dexmedetomidine infusion for the treatment of intractable delirium associated with cancer pain].
    Masui. The Japanese journal of anesthesiology, 2013, Volume: 62, Issue:12

    Topics: Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Fatal Outcome; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Pain, Intractable; Palliative Care; Treatment Outcome

2013
[Application of dexmedetomidine on mechanical ventilation weaning in delirium patients].
    Zhonghua wei zhong bing ji jiu yi xue, 2014, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Respiration, Artificial; Ventilator Weaning

2014
A case report of dexmedetomidine used to treat intractable pain and delirium in a tertiary palliative care unit.
    Palliative medicine, 2015, Volume: 29, Issue:3

    Topics: Analgesics, Non-Narcotic; Delirium; Dexmedetomidine; Female; Humans; Infusions, Subcutaneous; Middle Aged; Neuralgia; Pain, Intractable; Palliative Care; Uterine Cervical Neoplasms

2015
A retrospective comparison of dexmedetomidine versus midazolam for pediatric patients with congenital heart disease requiring postoperative sedation.
    Pediatric cardiology, 2015, Volume: 36, Issue:5

    Topics: Anesthetics, Intravenous; Child, Preschool; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Fentanyl; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Hypnotics and Sedatives; Incidence; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Length of Stay; Male; Midazolam; Postoperative Period; Retrospective Studies; Treatment Outcome; Ventilators, Mechanical

2015
Emergence delirium in children.
    Anaesthesia, 2015, Volume: 70, Issue:4

    Topics: Anesthesia, General; Delirium; Dexmedetomidine; Female; Humans; Magnetic Resonance Imaging; Male; Propofol

2015
Clinical effectiveness of a sedation protocol minimizing benzodiazepine infusions and favoring early dexmedetomidine: a before-after study.
    Critical care (London, England), 2015, Apr-02, Volume: 19

    Topics: Adult; Aged; Clinical Protocols; Controlled Before-After Studies; Delirium; Dexmedetomidine; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Midazolam; Middle Aged; Missouri; Respiration, Artificial; Tracheostomy

2015
Dexmedetomidine and emergence agitation.
    Anaesthesia, 2015, Volume: 70, Issue:7

    Topics: Anesthesia, General; Delirium; Dexmedetomidine; Female; Humans; Magnetic Resonance Imaging; Male; Propofol

2015
A reply.
    Anaesthesia, 2015, Volume: 70, Issue:7

    Topics: Anesthesia, General; Delirium; Dexmedetomidine; Female; Humans; Magnetic Resonance Imaging; Male; Propofol

2015
[Role of α7 nicotinic acetylcholine receptor in attenuation of endotoxin induced delirium with dexmedetomidine in mice].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:2

    Topics: Acetylcholinesterase; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Choline O-Acetyltransferase; Delirium; Dexmedetomidine; Endotoxemia; Endotoxins; Hippocampus; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Phosphopyruvate Hydratase; Random Allocation; Tumor Necrosis Factor-alpha

2016
The Evolving Approach to Brain Dysfunction in Critically Ill Patients.
    JAMA, 2016, Apr-12, Volume: 315, Issue:14

    Topics: Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Psychomotor Agitation; Respiration, Artificial

2016
[Effective Dexmedetomidine Administration for the Prevention of Emergence Agitation and Postoperative Delirium in Patients with a History of Postoperative Delirium].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:4

    Topics: Aged; Delirium; Dexmedetomidine; Female; Humans; Male; Postoperative Complications; Psychomotor Agitation

2016
What to Do When Haloperidol Fails to Treat Agitated Delirium: Is Dexmedetomidine the Next Step?
    Critical care medicine, 2016, Volume: 44, Issue:7

    Topics: Delirium; Dexmedetomidine; Haloperidol; Humans; Hypnotics and Sedatives

2016
Use of Dexmedetomidine in Liver Transplant Recipients With Postoperative Agitated Delirium.
    Transplantation proceedings, 2016, Volume: 48, Issue:4

    Topics: Adult; Aged; Antipsychotic Agents; Delirium; Dexmedetomidine; Female; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Liver Transplantation; Male; Midazolam; Middle Aged; Postoperative Complications; Postoperative Period; Retrospective Studies

2016
Dexmedetomidine to Reduce Intubation Time in Patients With Agitated Delirium.
    JAMA, 2016, Aug-16, Volume: 316, Issue:7

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intubation; Psychomotor Agitation

2016
Dexmedetomidine to Reduce Intubation Time in Patients With Agitated Delirium--Reply.
    JAMA, 2016, Aug-16, Volume: 316, Issue:7

    Topics: Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intubation; Psychomotor Agitation

2016
Pharmacy-Driven Dexmedetomidine Stewardship and Appropriate Use Guidelines in a Community Hospital Setting.
    The Annals of pharmacotherapy, 2017, Volume: 51, Issue:1

    Topics: Adult; Aged; Cost-Benefit Analysis; Delirium; Dexmedetomidine; Drug Utilization; Female; Hospital Bed Capacity, 300 to 499; Hospitals, Community; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Pharmacy Service, Hospital; Potentially Inappropriate Medication List; Practice Guidelines as Topic; Respiration, Artificial; Retrospective Studies

2017
Severe GHB withdrawal delirium managed with dexmedetomidine.
    The Medical journal of Australia, 2016, Sep-19, Volume: 205, Issue:6

    Topics: Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Sodium Oxybate; Substance Withdrawal Syndrome; Young Adult

2016
Valproate for agitation in critically ill patients: A retrospective study.
    Journal of critical care, 2017, Volume: 37

    Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA Agents; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Agitation; Retrospective Studies; Valproic Acid

2017
Comparing Dexmedetomidine With Haloperidol for the Treatment of Hyperactive Delirium in Nonintubated ICU Patients.
    Critical care medicine, 2016, Volume: 44, Issue:12

    Topics: Antipsychotic Agents; Delirium; Dexmedetomidine; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units

2016
[Comment on: Dexmedetomidine for delirium prophylaxis in elderly patients after non-cardiac surgery in the intensive care unit].
    Der Anaesthesist, 2017, Volume: 66, Issue:1

    Topics: Aged; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units

2017
Use of dexmedetomidine to treat delirium primarily caused by cannabis.
    The American journal of emergency medicine, 2017, Volume: 35, Issue:3

    Topics: Administration, Intravenous; Cannabis; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Marijuana Abuse; Marijuana Smoking; Substance Withdrawal Syndrome; Young Adult

2017
Preventing delirium: beyond dexmedetomidine.
    Lancet (London, England), 2017, 03-11, Volume: 389, Issue:10073

    Topics: Delirium; Dexmedetomidine; Humans; Intensive Care Units

2017
Preventing delirium: beyond dexmedetomidine - Authors' reply.
    Lancet (London, England), 2017, 03-11, Volume: 389, Issue:10073

    Topics: Delirium; Dexmedetomidine; Humans

2017
A case of infant delirium in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acids; Delirium; Deprescriptions; Dexmedetomidine; Diazepam; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Methadone; Midazolam; Phenobarbital; Postoperative Complications; Pregnancy; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Risperidone

2017
Tackling agitated delirium--the tip of the iceberg.
    Critical care (London, England), 2009, Volume: 13, Issue:3

    Topics: Antipsychotic Agents; Delirium; Dexmedetomidine; Haloperidol; Humans; Hypnotics and Sedatives; Psychomotor Agitation; Respiration, Artificial

2009
Dexmedetomidine and the successful management of electroconvulsive therapy postictal agitation: a case report.
    The journal of ECT, 2010, Volume: 26, Issue:2

    Topics: Adult; Combined Modality Therapy; Delirium; Dexmedetomidine; Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Psychomotor Agitation; Treatment Outcome

2010
Dexmedetomidine: perioperative applications in children.
    Paediatric anaesthesia, 2010, Volume: 20, Issue:3

    Topics: Adrenergic alpha-Agonists; Anxiety; Child; Child, Preschool; Delirium; Dexmedetomidine; Humans; Infant; Pain, Postoperative; Perioperative Care; Preanesthetic Medication

2010
[Incidence and duration of postoperative delirium after cardiac surgery : Comparison between dexmedetomidine and morphine for postoperative sedation and analgesia].
    Der Anaesthesist, 2010, Volume: 59, Issue:3

    Topics: Analgesics, Opioid; Cardiac Surgical Procedures; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Morphine; Pain, Postoperative; Postoperative Care; Postoperative Complications; Postoperative Period; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome

2010
The complex interplay between delirium, sepsis and sedation.
    Critical care (London, England), 2010, Volume: 14, Issue:3

    Topics: Brain; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Respiration, Artificial; Sepsis

2010
Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients.
    Critical care medicine, 2010, Volume: 38, Issue:12

    Topics: Aged; Cause of Death; Cohort Studies; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Length of Stay; Male; Midazolam; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Respiration, Artificial; Risk Assessment

2010
All this confusion is killin' me.
    Critical care medicine, 2010, Volume: 38, Issue:12

    Topics: Case-Control Studies; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Male; Midazolam; Prognosis; Survival Rate; Time Factors; Treatment Outcome

2010
Dexmedetomidine in cardiac surgery patients who fail extubation and present with a delirium state.
    The heart surgery forum, 2011, Volume: 14, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Cardiac Surgical Procedures; Continuous Positive Airway Pressure; Delirium; Dexmedetomidine; Female; Fentanyl; Health Status Indicators; Hemodynamics; Humans; Intensive Care Units; Male; Midazolam; Middle Aged; Psychometrics; Psychomotor Agitation; Respiration, Artificial; Ventilator Weaning

2011
Dexmedetomidine controls twitch-convulsive syndrome in the course of uremic encephalopathy.
    Journal of clinical anesthesia, 2011, Volume: 23, Issue:8

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Aortic Valve Stenosis; Brain Diseases; Delirium; Dexmedetomidine; Heart Valve Prosthesis Implantation; Humans; Male; Renal Dialysis; Renal Insufficiency, Chronic; Seizures; Syndrome; Time Factors; Tremor; Uremia

2011
Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents.
    Pain practice : the official journal of World Institute of Pain, 2012, Volume: 12, Issue:8

    Topics: Abdominal Abscess; Adrenergic alpha-2 Receptor Agonists; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Intravenous; Bupivacaine; Clonidine; Colectomy; Delirium; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Pain, Postoperative; Postoperative Complications; Propofol; Young Adult

2012
[Use of dexmedetomidine in a critically ill patient with hyperactive delirium: a case report].
    Masui. The Japanese journal of anesthesiology, 2012, Volume: 61, Issue:10

    Topics: Accidents, Traffic; Adrenergic alpha-2 Receptor Agonists; Adult; Critical Illness; Delirium; Dexmedetomidine; Embolization, Therapeutic; Emergencies; Humans; Hypnotics and Sedatives; Intensive Care Units; Liver; Male; Postoperative Complications

2012
[Preliminary experience with dexmedetomidine treatment of confusional state and hyperadrenergic states at an intensive care unit].
    Revista espanola de anestesiologia y reanimacion, 2002, Volume: 49, Issue:8

    Topics: Adult; Aged; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Postoperative Period; Receptors, Adrenergic

2002
[Efficacy of dexmedetomidine for controlling delirium in intensive care unit patients].
    Masui. The Japanese journal of anesthesiology, 2007, Volume: 56, Issue:10

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Delirium; Dexmedetomidine; Female; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Respiratory Insufficiency

2007
Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients.
    JAMA, 2008, Apr-02, Volume: 299, Issue:13

    Topics: Conscious Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Research Design; Respiration, Artificial

2008