dexmedetomidine has been researched along with Critical Illness in 154 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (7.14) | 29.6817 |
| 2010's | 79 (51.30) | 24.3611 |
| 2020's | 64 (41.56) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, S; Jang, EJ; Kim, D; Lee, H; Lee, J; Oh, SY; Ryu, HG; Yoo, S | 1 |
| An, XH; Dong, CH; Gao, CN; Li, DC; Li, N; Tan, Q; Yang, L | 1 |
| Jiang, X; Yan, M | 1 |
| Chan, T; Dervan, LA; Koth, AM; Tjoeng, YL; Watson, RS | 1 |
| Connor, K; Cooper, K; Groth, C; Prasad, P; Rappaport, S; Schranz, E | 1 |
| Giangregorio, M; Greco, C; Homoki, A; Kleinman, ME; Li, L; Mahoney, J; Mansfield, L; Manzi, SF; Solodiuk, JC; Sweet, E | 1 |
| Liviskie, CJ; McPherson, C; Vesoulis, ZA; Zeller, B | 1 |
| Jørgen Jennum, P; Knudsen, T; Oxlund, J; Sörberg, M; Toft, P | 1 |
| Bensadoun, E; Flannery, AH; James, W; Kellum, B; Kressin, CL; Lawless, B | 1 |
| Chen, T; Fu, Q; Jia, H; Liu, B; Mudabbar, MS; Yang, T | 1 |
| Cao, YY; Chen, Q; Lu, WH; Ma, WJ; Qi, YP; Wang, Z; Xiao, S; Xu, QC | 1 |
| Deng, Y; Hu, C; Jin, X; Jing, X; Kang, Y; Liang, G; Liao, X; Tang, Z; Tao, L; Tian, Y; Wang, B; Wang, P; Wang, Z; Yang, J; Yang, Y; Yin, W; Zhang, Z; Zhou, Y | 1 |
| Ask, J; Chlan, LL; Gajic, O; Mandrekar, J; Skaar, DJ; Tracy, MF; Weinert, CR | 1 |
| Al Duhailib, Z; Alhazzani, W; Alshahrani, M; Alshamsi, F; Carayannopoulos, KL; Centofanti, J; Chaudhuri, D; Devlin, JW; Ergan, B; Granholm, A; Holbrook, A; Honarmand, K; Karachi, T; Khorochkov, E; Lewis, K; Møller, MH; Needham, DM; Nishida, O; Pandharipande, P; Perri, D; Piticaru, J; Rochwerg, B; Shehabi, Y; Soth, M; Spatafora, L; Spence, J; Yuan, Y | 1 |
| Ingebrigtson, M; Miller, JT | 1 |
| Ali, S; Deng, J; Heybati, K; Mohananey, D; Ramakrishna, H; Villablanca, P; Zhou, F | 1 |
| Jennum, PJ; Knudsen, T; Oxlund, J; Sörberg, M; Strøm, T; Toft, P | 1 |
| Akimoto, Y; Itagaki, T; Momota, K; Nakano, Y; Nunomura, T; Oto, J; Sato, H; Sato, K; Tane, N; Ueno, Y | 1 |
| An, S; Chen, Z; Hu, H; Jin, Y; Li, L; Sha, T; Wu, F; Wu, J; Zeng, Z | 1 |
| Anstey, C; Bailey, M; Fraser, JF; Moore, JPR; Murray, L; Reade, MC; Shehabi, Y; Singer, M | 1 |
| Burry, L; De Jong, A | 1 |
| Jennum, PJ; Knudsen, T; Leonthin, H; Oxlund, J; Toft, P | 1 |
| Ney, L; Saller, T | 1 |
| DeGrado, JR; Goodberlet, MZ; Lupi, KE; Marino, KK; Schuler, BR; Ware, LR | 1 |
| Behal, M; Bissell, B; Mefford, B; Pandya, K; Robbins, B; Wiegand, A | 1 |
| Comert, B; Ergan, B; Ergun, B; Gokmen, AN; Heybeli, C; Kucuk, M; Ozturk, MC; Yakar, MN | 1 |
| Jiang, L; Jiang, Z; Lu, G; Qian, J; Yang, A; Yang, J; Zhou, B | 1 |
| Harada, H; Ikeda, K; Kamei, J; Kato, T; Kitajima, N; Kuriyama, A; Maeda, J; Matsuyama, A; Minami, T; Mizota, T; Ohtsuru, S; Sakai, Y; Sato, Y; Takatani, Y; Ueno, K; Watanabe, H; Yamaji, K; Yamashita, Y | 1 |
| Meade-Aguilar, JA; Pérez-Nieto, OR; Reyes-Monge, RA; Rodríguez-Guevara, I; Zamarrón-López, EI | 1 |
| Gao, P; Jin, Y; Liu, J; Wang, H; Wang, W; Zhang, P | 1 |
| Gao, X; Li, R; Qi, H; Ren, L; Shang, Y; Shu, H; Tang, Y; Xu, J; Yang, X; Yuan, S; Zou, X | 1 |
| Alaniz, C; Farina, N | 1 |
| Baillie, JK; Edwardson, SA; Flanders, CA; Rocke, AS; Walsh, TS | 1 |
| Attridge, RL; Christina Gutierrez, G; Glaess, SS | 1 |
| Weeks, SM | 1 |
| Crowley, KE; Geiger, KL; Hacobian, G; Urben, L | 1 |
| Bollig, RW; Daley, BJ; Heidel, RE; McMillen, JC; Radtke, J; Roberts, RF; Taylor, JE; Winings, NA | 1 |
| Amigoni, A; Coscini, N; Daverio, M; Frigo, AC; Mondardini, MC; Sperotto, F; Zanetto, L | 1 |
| Lai, IK; Li, R; Maze, M; Pan, JZ; Zhang, P | 1 |
| Barletta, JF; Erstad, BL | 1 |
| Grgurich, P; Lei, Y; Nault, K; Salah, J | 1 |
| Andersen, LW; Berg, KM; Granfeldt, A; Grossestreuer, AV; Holmberg, MJ; Moskowitz, A | 1 |
| Coopersmith, CM; Paterson, CW | 1 |
| Anderson, BJ; Erickson, SJ; Festa, MS; Long, DA; Millar, J; Shehabi, Y; Straney, L | 1 |
| Armahizer, MJ; Heavner, MS; Kurczewski, L; Maciel, CB; Owusu, KA; Zichichi, A | 1 |
| Adamczyk, K; Chiu, SH; Kaplan, JB; Pathan, S; Shah, CV | 1 |
| Arnold, C | 1 |
| Collier, TE; Farrell, LB; Kataria, VK; Killian, AD | 1 |
| Gong, CC; Liu, X; Tang, Y; Wang, DF; Xiong, J | 1 |
| DeMott, JM; DiCesare, MA; Rech, MA | 1 |
| Bellomo, R; Deane, AM; Lankadeva, YR; May, CN; Plummer, MP; Shehabi, Y | 1 |
| Anzueto, A; Bernard, GR; Brummel, NE; Bui, LN; Devlin, JW; Dittus, RS; Duprey, MS; Ely, EW; Girard, TD; Gropper, MA; Guntupalli, KK; Hoskins, AS; Hughes, CG; Jackson, JC; Kiehl, AL; Mailloux, PT; O'Neal, HR; Orun, OM; Pandharipande, PP; Patel, MB; Pun, BT; Raman, R; Sanders, RD; Snyder, A; Stashenko, GJ; Stollings, JL; Swan, JT | 1 |
| Amigoni, A; Sperotto, F | 1 |
| Geven, BM; Maaskant, JM; van Woensel, JBM; Ward, CS | 1 |
| Albert, M; Bernard, F; Bilodeau, V; Burry, L; Frenette, AJ; Saavedra-Mitjans, M; Williamson, DR | 1 |
| Abdul-Aziz, AA; Adie, SK; Farina, N; Konerman, MC; Lee, R; Thomas, MP | 1 |
| Arabi, YM; Bailey, M; Bass, FE; Bellomo, R; Howe, BD; Kadiman, SB; McArthur, CJ; Reade, MC; Seppelt, IM; Serpa Neto, A; Shehabi, Y; Takala, J; Webb, SA; Wise, MP | 1 |
| Bailey, M; Balachandran, M; Banneheke, PP; Belletti, A; Bellomo, R; Grayson, KE; Naorungroj, T; Serpa-Neto, A; Shehabi, Y; Wright, JD; Yanase, F; Young, PJ | 1 |
| Duan, M; Ji, C; Liu, J; Liu, S; Yang, R; Zhao, H; Zhao, R | 1 |
| Atyia, SA; Cape, KM; May, CC; Smetana, KS; Thompson, MJ; Tong, MC | 1 |
| Al-Bassam, W; Bellomo, R; James, A; Murfin, B; Shehabi, Y | 1 |
| Joynt, GM; Lee, A; Tse, AHW; Yan, X; Yang, M; Zhang, L; Zuo, Z | 1 |
| Järvisalo, MJ; Uusalo, P; Valtonen, M | 1 |
| Gottlieb, M; Long, B | 1 |
| Fu, Q; Fu, S; Hu, K; Lu, W; Luo, X | 1 |
| Blum, A; Gantner, L; Hollinger, A; Ledergerber, K; Marsch, S; Rüegg, S; Siegemund, M; Steiner, LA; Sutter, R; von Felten, S; Zimmermann, S | 1 |
| Fierro, MA; Goucher Miranda, H; Krystal, AD | 1 |
| Chang, XN; Chen, Y; Dong, CM; Du, H; Wei, BH | 1 |
| Banasch, HL; Boulter, LL; Dersch-Mills, DA; Gilfoyle, E | 1 |
| Chui, SJ; Harbourt, K; Pajoumand, M; Pruskowski, KA; Reynolds, HN | 1 |
| Arabi, Y; Bass, F; Bellomo, R; Forbes, AB; Howe, BD; Kadiman, S; McArthur, C; Reade, MC; Seppelt, I; Shehabi, Y; Takala, J; Webb, S; Wise, MP | 1 |
| Gallego-Ligorit, L; Iglesias, M; Pajares, A; Sanjuán-Villarreal, TA; Vallés-Torres, J; Vives, M | 1 |
| Ely, EW; Ferrell, BA; Girard, TD; Hughes, CG; Pandharipande, PP; Patel, MB; Scheinin, M; Shintani, AK; Stollings, JL; Thompson, JL; Wilkinson, GR | 1 |
| Amigoni, A; Blangetti, I; Casella, G; Chelazzi, C; Conti, G; Forfori, F; Garisto, C; Moltrasio, M; Mondardini, MC; Pasero, D; Principi, T; Ricci, Z; Romagnoli, S; Tarantino, F | 1 |
| Devlin, JW; Duprey, MS; Hill, NS; Skrobik, Y | 1 |
| Joynt, GM; Lee, A; Ling, L; Tse, AHW | 1 |
| Hammond, DA; Nelson, KM; Patel, GP | 1 |
| Cacchione, PZ; Compton, P; Pavone, KJ; Polomano, RC; Winner, L | 1 |
| Amigoni, A; Brugnaro, L; Campagnano, E; Daverio, M; Dusio, MP; Ferrario, S; Ferrero, F; Mondardini, MC; Rossetti, E; Savron, F; Sperotto, F; Vasile, B; Vitale, F | 1 |
| Banasch, HL; Dersch-Mills, DA; Howlett, A; Yusuf, K | 1 |
| Barbateskovic, M; Jakobsen, JC; Maagaard, M; Perner, A; Wetterslev, J | 2 |
| Arabi, YM; Bailey, M; Bass, FE; Bellomo, R; Bin Kadiman, S; Howe, BD; McArthur, CJ; Murray, L; Reade, MC; Seppelt, IM; Shehabi, Y; Takala, J; Webb, SA; Wise, MP | 1 |
| Coursin, DB; Skrobik, Y | 1 |
| Guo, FM; Pan, C; Qiu, HB; Yang, Y; Yu, T | 1 |
| Ahtola-Sätilä, T; Garratt, C; Pohjanjousi, P; Sarapohja, T; Välitalo, PA; Wighton, A | 1 |
| Bailey, M; Bass, F; Bellomo, R; Howe, B; McArthur, C; Murray, L; Reade, MC; Seppelt, IM; Shehabi, Y; Webb, S; Weisbrodt, L | 1 |
| McAuley, DF; Page, VJ | 1 |
| Chen, SQ; Liu, KX; Wen, SH; Xia, ZQ; Xie, CB; Yao, X | 1 |
| Doi, M; Fujino, Y; Kakihana, Y; Kawai, M; Matsuda, K; Nishi, S; Ozaki, M; Shiokawa, Y; Takeda, J; Takinami, M; Tanaka, K | 1 |
| Guo, F; Huang, Y; Qiu, H; Teboul, JL; Yang, Y; Yu, T | 1 |
| Fen, L; Ji, J; Wang, A; Wang, X | 1 |
| Bauer, PR; Dierkhising, RA; Frazee, EN; Leung, JG; Nelson, S; Personett, HA | 1 |
| Cabrini, L; Feltracco, P; Finco, G; Greco, T; Landoni, G; Neto, CN; Pasin, L; Vittorio, A; Zangrillo, A | 1 |
| Buckley, MS; Empey, PE; Holliday, SF; Kane-Gill, SL; Smithburger, PL | 1 |
| Brichant, JF; Mavropoulos, G; Minguet, G | 1 |
| Cowl, AS; Cummings, BM; El Saleeby, CM; Noviski, N; Shank, ES; Yager, PH | 1 |
| Alexopoulou, C; Bolaki, M; Diamantaki, E; Georgopoulos, D; Kokkini, S; Kondili, E; Psarologakis, C | 1 |
| Bioc, JJ; Cucchi, J; Dasta, JF; Devlin, JW; Edwards, RA; Fraser, GL; Magee, C | 1 |
| Belletti, A; Di Prima, AL; Isella, F; Landoni, G; Nardelli, P; Pasin, L; Taddeo, D; Zangrillo, A | 1 |
| Erstad, BL; Patanwala, AE | 1 |
| Di Gennaro, JL; Irby, GA; Whalen, LD; Yanay, O; Zimmerman, JJ | 1 |
| Altawalbeh, S; Anthes, A; Benedict, N; Felbinger, M; Kane-Gill, S; Ridenour, T | 1 |
| Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC | 1 |
| Bozza, FA; do Brasil, PE; Ely, EW; Salluh, JI; Serafim, RB; Soares, M; Tura, BR | 1 |
| Dierkhising, RA; Frazee, EN; Ice, CJ; Kashyap, R; Oeckler, RA; Personett, HA | 1 |
| Adjepong, YA; Lukens, C; Manthous, CA; Musial, B; Perez, R; Stewart, R | 1 |
| Jutel, A; Sutton, LJ | 1 |
| Blackwood, B; Brazzelli, M; Campbell, M; Cruickshank, M; Fraser, C; Gordon, A; Henderson, L; MacLennan, G | 1 |
| An, Y; Feng, Y; Liu, D; Lyu, J | 1 |
| Bulloch, MN; Burry, L; Chan, C; Devabhakthuni, S; Dixit, D; Endicott, J; Ramos, L; Tobia, A; Yeung, SY | 1 |
| Bartkowska-Śniatkowska, A; Bienert, A; Borsuk, A; Grześkowiak, E; Kaliszan, R; Rosada-Kurasińska, J; Siluk, D; Szerkus, O; Warzybok, J; Wiczling, P | 1 |
| Hayashida, K; Ikai, H; Imanaka, Y; Murakami, G; Nishimura, M; Umegaki, T | 1 |
| Asaro, LA; Cowl, AS; Curley, MA; Dodson, BL; Grant, MJ; Hall, BA; Munkwitz, MM; Schneider, JB; Simone, SL; Wypij, D | 1 |
| Cao, Y; Han, T; Li, Y; Lyu, Y; Wang, D | 1 |
| Dziodzio, JT; Fontaine, GV; Fraser, GL; Gagnon, DJ; Lerwick, PA; Lucas, FL; Miller, RR; Riker, RR; Sihler, KC; Smith, KE | 1 |
| Meersch, M; Zarbock, A | 1 |
| Andreolio, C; Baldasso, E; Ferlini, R; Piccoli, R; Piva, JP | 1 |
| Kress, JP; Wunsch, H | 1 |
| Bokesch, PM; Byrne, DW; Ceraso, D; Ely, EW; Koura, F; Margolis, BD; Riker, RR; Rocha, MG; Shehabi, Y; Whitten, P; Wisemandle, W | 1 |
| Czaja, AS; Zimmerman, JJ | 1 |
| Cook, CH; Dasta, JF; Gerlach, AT; Martin, LC; Steinberg, S | 1 |
| Benefield, RJ; Honey, BL; Johnson, PN; Miller, JL | 1 |
| Kargi, M; Memiş, D; Sut, N | 1 |
| Dasta, JF; Gerlach, AT; Murphy, CV | 1 |
| Tobias, JD | 1 |
| Bass, F; Chen, J; Hammond, N; Nakae, H; Nicholson, L; Shehabi, Y | 1 |
| Chlan, LL; Skaar, DJ; Tracy, MF; Weinert, CR | 1 |
| Ho, KM; Tan, JA | 1 |
| Griswold, M; Ledroux, S; Lewin, JJ; Mirski, MA; Murakami, P; Thompson, C; Zink, EK | 1 |
| Adamson, PC; Barrett, JS; Gastonguay, MR; Godinez, RI; Kang, DS; Nicolson, SC; Su, F; Zuppa, AF | 1 |
| Kress, JP | 1 |
| Kahn, JM; Kramer, AA; Li, G; Rubenfeld, GD; Sladen, RN; Wagener, G; Wunsch, H | 1 |
| Guinter, JR; Kristeller, JL | 1 |
| Schwenger, E; Tejani, AM | 1 |
| Bokesch, PM; Ely, EW; Riker, RR; Shehabi, Y; Shintani, A; Wisemandle, W | 1 |
| Hamada, S; Josserand, J; Mantz, J | 1 |
| Coursin, DB; Joffe, A | 1 |
| Devabhakthuni, S; Kufera, JA; Pajoumand, M; Stein, DM; Watson, K; Williams, C | 1 |
| Aantaa, R; Ahtola-Sätilä, T; Garratt, C; Iirola, T; Kentala, E; Lahtinen, M; Laitio, R; Olkkola, KT; Wighton, A | 1 |
| Berry, DE; Burbano, NH; Munoz, RA; Orr, RA; Otero, AV | 1 |
| Ely, EW; Hipp, DM | 1 |
| Bhutta, AT; Gossett, JM; Gupta, P; Lam, F; Morales, L; Tobias, JD | 1 |
| Cook, CH; Gerlach, AT; Jones, GM; Murphy, CV | 1 |
| Botros, DG; DeMuro, JP; Hanna, AF; Wirkowski, E | 1 |
| Abd-Elsayed, A; Argalious, M; Doyle, DJ; Ebrahim, Z; Farag, E | 1 |
| Gossett, JM; Gupta, P; Roth, SJ; Sabati, A; Tesoro, TM; Tobias, JD; Whiteside, W | 1 |
| Al-Qadhee, NS; Devlin, JW; Skrobik, Y | 1 |
| Matsuda, T; Matsuzaki, S; Tamada, N; Yamaguchi, Y | 1 |
| Cochrane, RE; Krisl, JC; MacLaren, R; Mueller, SW | 1 |
| Rosen, DA | 1 |
| Hekimoğlu, S; Memiş, D; Süt, N; Vatan, I; Yandim, T; Yüksel, M | 1 |
| Angelini, G; Coursin, DB; Ketzler, JT | 1 |
| Cavaliere, F; Maze, M; Scarfini, C | 1 |
35 review(s) available for dexmedetomidine and Critical Illness
| Article | Year |
|---|---|
Dexmedetomidine vs other sedatives in critically ill mechanically ventilated adults: a systematic review and meta-analysis of randomized trials.
Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Randomized Controlled Trials as Topic; Respiration, Artificial | 2022 |
Outcomes of dexmedetomidine versus propofol sedation in critically ill adults requiring mechanical ventilation: a systematic review and meta-analysis of randomised controlled trials.
Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial | 2022 |
Niche Roles for Dexmedetomidine in the Intensive Care Unit.
Topics: Alcoholism; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Substance Withdrawal Syndrome | 2023 |
The effect of dexmedetomidine and clonidine on the inflammatory response in critical illness: a systematic review of animal and human studies.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Clonidine; Critical Illness; Dexmedetomidine; Disease Models, Animal; Humans; Inflammation | 2019 |
Clonidine as a strategy for discontinuing dexmedetomidine sedation in critically ill patients: A narrative review.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Substitution; Humans; Hypnotics and Sedatives; Risk Factors; Substance Withdrawal Syndrome | 2020 |
Pharmacological Options for Treating Delirium in Critically Ill Adults.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Antipsychotic Agents; Critical Illness; Delirium; Dexmedetomidine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intensive Care Units; Randomized Controlled Trials as Topic; Respiration, Artificial | 2020 |
Dexmedetomidine for Prolonged Sedation in the PICU: A Systematic Review and Meta-Analysis.
Topics: Adolescent; Anesthesia; Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units, Pediatric; Retrospective Studies | 2020 |
Drug dosing in the critically ill obese patient-a focus on sedation, analgesia, and delirium.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Benzodiazepines; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Etomidate; Haloperidol; Humans; Ketamine; Obesity; Pain Management; Quetiapine Fumarate | 2020 |
Identification, collection, and reporting of harms among non-industry-sponsored randomized clinical trials of pharmacologic interventions in the critically ill population: a systematic review.
Topics: Adrenal Cortex Hormones; Antipsychotic Agents; Critical Illness; Dexmedetomidine; Drug-Related Side Effects and Adverse Reactions; Haloperidol; Humans; Hypnotics and Sedatives; Pharmacological Phenomena; Randomized Controlled Trials as Topic | 2020 |
Role of dexmedetomidine in the treatment of delirium in critically ill patients: a systematic review and meta-analysis.
Topics: Adult; Bradycardia; Critical Illness; Delirium; Dexmedetomidine; Humans | 2021 |
Emerging benefits and drawbacks of α
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Clonidine; Critical Illness; Dexmedetomidine; Humans; Receptors, Adrenergic, alpha-2; Sepsis | 2021 |
Use of Dexmedetomidine in Cardiothoracic and Vascular Anesthesia.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Cardiac Procedures; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Vascular Surgical Procedures | 2018 |
Light sedation with dexmedetomidine: a practical approach for the intensivist in different ICU patients.
Topics: Acute Disease; Adult; Cardiac Surgical Procedures; Cerebrovascular Disorders; Child; Conscious Sedation; Critical Care; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Sepsis | 2018 |
Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review.
Topics: Adult; Analgesics; Critical Illness; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Midazolam; Morphine; Propofol; Remifentanil; Sufentanil; Time Factors | 2018 |
Evaluating the use of dexmedetomidine for the reduction of delirium: An integrative review.
Topics: Adrenergic alpha-2 Receptor Agonists; Cardiac Surgical Procedures; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Respiration, Artificial | 2018 |
Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a meta-analysis of randomized clinical trials.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Randomized Controlled Trials as Topic | 2013 |
Dexmedetomidine as a sedative agent in critically ill patients: a meta-analysis of randomized controlled trials.
Topics: Airway Extubation; Bradycardia; Critical Care; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypotension; Length of Stay; Randomized Controlled Trials as Topic; Time Factors | 2013 |
Interpatient variability in dexmedetomidine response: a survey of the literature.
Topics: Critical Care; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Polymorphism, Genetic; Precision Medicine | 2014 |
[Alpha-2 adrenoreceptor agonists in anaesthesia and intensive care medicine].
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Clonidine; Critical Care; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units | 2014 |
Dexmedetomidine reduces the risk of delirium, agitation and confusion in critically Ill patients: a meta-analysis of randomized controlled trials.
Topics: Confusion; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Psychomotor Agitation; Randomized Controlled Trials as Topic | 2014 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors | 2015 |
Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review.
Topics: Antipsychotic Agents; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Haloperidol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Neuroprotective Agents; Postoperative Complications; Quetiapine Fumarate; Respiration, Artificial; Risperidone; Rivastigmine; Treatment Outcome | 2015 |
Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clinical Trials as Topic; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Respiration, Artificial; Technology Assessment, Biomedical | 2016 |
Management of Acute Alcohol Withdrawal Syndrome in Critically Ill Patients.
Topics: Baclofen; Benzodiazepines; Critical Illness; Dexmedetomidine; Ethanol; Humans; Length of Stay; Phenobarbital; Substance Withdrawal Syndrome | 2016 |
Renal protection in the 21st century.
Topics: Acute Kidney Injury; Critical Care; Critical Illness; Crystalloid Solutions; Dexmedetomidine; Fluid Therapy; Hemodynamics; Humans; Hypnotics and Sedatives; Isotonic Solutions; Kidney | 2016 |
Alpha2-receptor agonists for treatment and prevention of iatrogenic opioid abstinence syndrome in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Child; Clonidine; Critical Illness; Dexmedetomidine; Drug Tolerance; Humans; Opioid-Related Disorders; Substance Withdrawal Syndrome | 2009 |
An updated focused review of dexmedetomidine in adults.
Topics: Adrenergic alpha-Agonists; Adult; Clinical Trials as Topic; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Economics, Pharmaceutical; Humans; Hypnotics and Sedatives; Time Factors | 2009 |
Use of dexmedetomidine as a sedative and analgesic agent in critically ill adult patients: a meta-analysis.
Topics: Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Randomized Controlled Trials as Topic | 2010 |
Prolonged infusions of dexmedetomidine in critically ill patients.
Topics: Clinical Trials as Topic; Critical Illness; Dexmedetomidine; Drug Administration Schedule; Humans; Hypnotics and Sedatives; Infusions, Intravenous | 2010 |
Dexmedetomidine: new insights.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia, Conduction; Animals; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Neuroprotective Agents | 2011 |
Pharmacological and nonpharmacological management of delirium in critically ill patients.
Topics: Analgesics, Non-Narcotic; Antipsychotic Agents; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Humans; Respiration, Artificial | 2012 |
The use of dexmedetomidine in anesthesia and intensive care: a review.
Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Animals; Bradycardia; Cerebrovascular Circulation; Critical Care; Critical Illness; Dexmedetomidine; Drug Administration Routes; Drug Interactions; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedatives; Hypotension; Neuroprotective Agents | 2012 |
Pharmacologic prevention and treatment of delirium in critically ill and non-critically ill hospitalised patients: a review of data from prospective, randomised studies.
Topics: Aged; Antipsychotic Agents; Critical Illness; Delirium; Dexmedetomidine; Hospitalization; Humans; Intensive Care Units; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Research Design | 2012 |
Use of propofol and other nonbenzodiazepine sedatives in the intensive care unit.
Topics: Critical Illness; Dexmedetomidine; Etomidate; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol | 2001 |
New agents for sedation in the intensive care unit.
Topics: Adrenergic alpha-Agonists; Anti-Anxiety Agents; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Piperidines; Receptors, Adrenergic, alpha; Remifentanil | 2001 |
33 trial(s) available for dexmedetomidine and Critical Illness
| Article | Year |
|---|---|
Nocturnal dexmedetomidine alleviates post-intensive care syndrome following cardiac surgery: a prospective randomized controlled clinical trial.
Topics: Cardiac Surgical Procedures; Critical Illness; Delirium; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Prospective Studies | 2021 |
Dexmedetomidine and sleep quality in mechanically ventilated critically ill patients: study protocol for a randomised placebo-controlled trial.
Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Randomized Controlled Trials as Topic; Respiration, Artificial; Sleep Quality | 2022 |
Dexmedetomidine dosage in critically ill patients undergoing intraoperative wake-up test: A randomized controlled trial.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Propofol; Remifentanil; Scoliosis | 2022 |
Effect of Dexmedetomidine on Intestinal Barrier in Patients Undergoing Gastrointestinal Surgery-A Single-Center Randomized Clinical Trial.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Critical Illness; Dexmedetomidine; Digestive System Surgical Procedures; Humans; Lactates; Midazolam; Tumor Necrosis Factor-alpha | 2022 |
Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Respiration, Artificial | 2022 |
Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial.
Topics: Aftercare; Analgesics, Opioid; Anxiety; COVID-19; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pandemics; Patient Discharge; Quality of Life; Randomized Controlled Trials as Topic; Respiration, Artificial; Ventilators, Mechanical | 2022 |
Sleep quality and quantity determined by polysomnography in mechanically ventilated critically ill patients randomized to dexmedetomidine or placebo.
Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Polysomnography; Respiration, Artificial; Sleep Quality | 2023 |
The quality and quantity of sleep on dexmedetomidine during high-flow nasal cannula oxygen therapy in critically ill patients.
Topics: Cannula; Critical Illness; Dexmedetomidine; Humans; Oxygen; Sleep | 2022 |
Stress response during early sedation with dexmedetomidine compared with usual-care in ventilated critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Prospective Studies; Respiration, Artificial; Sepsis | 2022 |
Dexmedetomidine versus haloperidol for sedation of non-intubated patients with hyperactive delirium during the night in a high dependency unit: study protocol for an open-label, parallel-group, randomized controlled trial (DEX-HD trial).
Topics: Critical Illness; Delirium; Dexmedetomidine; Drugs, Investigational; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Psychomotor Agitation; Randomized Controlled Trials as Topic | 2023 |
Remimazolam besylate versus propofol for deep sedation in critically ill patients: a randomized pilot study.
Topics: Critical Illness; Deep Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Pilot Projects; Propofol; Prospective Studies; Respiration, Artificial | 2023 |
Dexmedetomidine versus propofol for prolonged sedation in critically ill trauma and surgical patients.
Topics: Adolescent; Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Prospective Studies | 2021 |
Dexmedetomidine Sedation in Mechanically Ventilated Critically Ill Children: A Pilot Randomized Controlled Trial.
Topics: Adolescent; Australia; Child; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; New Zealand; Pilot Projects; Prospective Studies; Respiration, Artificial | 2020 |
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Topics: Adult; Cognition; Conscious Sedation; Critical Illness; Dexmedetomidine; Double-Blind Method; Humans; Hypnotics and Sedatives; Kaplan-Meier Estimate; Propofol; Respiration, Artificial; Sepsis | 2021 |
Early sedation with dexmedetomidine in ventilated critically ill patients and heterogeneity of treatment effect in the SPICE III randomised controlled trial.
Topics: Adult; Aged; Bayes Theorem; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Respiration, Artificial | 2021 |
The Effect of Early Sedation With Dexmedetomidine on Body Temperature in Critically Ill Patients.
Topics: Aged; Body Temperature; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hyperthermia; Hypnotics and Sedatives; Male; Middle Aged; Respiration, Artificial; Time Factors | 2021 |
Comparison of propofol and dexmedetomidine infused overnight to treat hyperactive and mixed ICU delirium: a protocol for the Basel ProDex clinical trial.
Topics: Critical Illness; Delirium; Dexmedetomidine; Electroencephalography; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Length of Stay; Propofol; Quality of Life; Research Design; Sleep; Switzerland; Time Factors | 2017 |
Development and validation of risk-stratification delirium prediction model for critically ill patients: A prospective, observational, single-center study.
Topics: Academic Medical Centers; Age Factors; APACHE; Area Under Curve; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Incidence; Logistic Models; Male; Middle Aged; Models, Biological; Multivariate Analysis; Prognosis; Prospective Studies; Respiration, Artificial; Risk; ROC Curve | 2017 |
The SPICE III study protocol and analysis plan: a randomised trial of early goaldirected sedation compared with standard care in mechanically ventilated patients.
Topics: Clinical Protocols; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Prospective Studies; Research Design; Respiration, Artificial | 2017 |
Sedative Plasma Concentrations and Delirium Risk in Critical Illness.
Topics: Aged; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Logistic Models; Lorazepam; Male; Middle Aged; Respiration, Artificial | 2018 |
Low-Dose Nocturnal Dexmedetomidine Prevents ICU Delirium. A Randomized, Placebo-controlled Trial.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Night Care; Placebo Effect; Propofol; Time Factors | 2018 |
Early Sedation with Dexmedetomidine in Critically Ill Patients.
Topics: Adult; Aged; Bradycardia; Conscious Sedation; Critical Illness; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Intention to Treat Analysis; Male; Midazolam; Middle Aged; Propofol; Respiration, Artificial; Time Factors; Treatment Outcome | 2019 |
Population pharmacokinetics of dexmedetomidine in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Critical Illness; Dexmedetomidine; Female; Humans; Male; Middle Aged; Models, Biological | 2013 |
Early goal-directed sedation versus standard sedation in mechanically ventilated critically ill patients: a pilot study*.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Airway Extubation; Algorithms; APACHE; Benzodiazepines; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Drug Utilization; Feasibility Studies; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Pilot Projects; Propofol; Prospective Studies; Respiration, Artificial; Restraint, Physical | 2013 |
Safety and efficacy of dexmedetomidine for long-term sedation in critically ill patients.
Topics: Aged; Aged, 80 and over; Analgesics; Critical Illness; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Male; Middle Aged; Prospective Studies; Time Factors | 2014 |
The effects of propofol and dexmedetomidine infusion on fluid responsiveness in critically ill patients.
Topics: Aged; Aged, 80 and over; Critical Illness; Dexmedetomidine; Female; Fluid Therapy; Hemodynamics; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Leg; Male; Middle Aged; Posture; Propofol; Prospective Studies; Shock; Single-Blind Method; Treatment Outcome | 2013 |
Effects of dexmedetomidine on cerebral blood flow in critically ill patients with or without traumatic brain injury: a prospective controlled trial.
Topics: Adult; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Critical Illness; Dexmedetomidine; Female; Glasgow Coma Scale; Heart Rate; Humans; Hypnotics and Sedatives; Intracranial Pressure; Male; Middle Aged; Prospective Studies; Treatment Outcome | 2013 |
[The influence of the sedation based on remifentanil analgesia on the occurrence of delirium in critically ill patients].
Topics: Analgesia; Arterial Pressure; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Midazolam; Pain; Piperidines; Prospective Studies; Remifentanil; Respiration, Artificial | 2015 |
Dexmedetomidine Use in Critically Ill Children With Acute Respiratory Failure.
Topics: Acute Disease; Adolescent; Airway Extubation; Child; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Intubation, Intratracheal; Male; Prospective Studies; Respiration, Artificial; Respiratory Insufficiency; Treatment Outcome | 2016 |
Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial.
Topics: Adrenergic alpha-Agonists; Aged; APACHE; Conscious Sedation; Critical Illness; Delirium; Dexmedetomidine; Double-Blind Method; Female; GABA Modulators; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Length of Stay; Male; Midazolam; Middle Aged; Prospective Studies; Respiration, Artificial | 2009 |
Cognitive improvement during continuous sedation in critically ill, awake and responsive patients: the Acute Neurological ICU Sedation Trial (ANIST).
Topics: Acrylates; Adult; Aged; Cognition; Conscious Sedation; Critical Illness; Cross-Over Studies; Dexmedetomidine; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Neuropsychological Tests; Prospective Studies; Respiration, Artificial; Treatment Outcome | 2010 |
Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Half-Life; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Metabolic Clearance Rate; Middle Aged | 2011 |
Effects of midazolam and dexmedetomidine on inflammatory responses and gastric intramucosal pH to sepsis, in critically ill patients.
Topics: Critical Illness; Dexmedetomidine; Gastric Acidity Determination; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Inflammation Mediators; Midazolam; Sepsis | 2007 |
86 other study(ies) available for dexmedetomidine and Critical Illness
| Article | Year |
|---|---|
Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours.
Topics: Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Propofol; Republic of Korea; Respiration, Artificial; Retrospective Studies; Time Factors | 2021 |
Comparing the impact on the prognosis of acute myocardial infarction critical patients of using midazolam, propofol, and dexmedetomidine for sedation.
Topics: Aged; Aged, 80 and over; Coronary Care Units; Critical Illness; Databases, Factual; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Myocardial Infarction; Propofol; Respiration, Artificial; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2021 |
Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes.
Topics: Benzodiazepines; Child; Child, Preschool; Critical Illness; Delirium; Dexmedetomidine; Humans; Intensive Care Units; Intensive Care Units, Pediatric; Length of Stay; Respiration, Artificial; Retrospective Studies; Risk Factors | 2022 |
A Retrospective Characterization of Dexmedetomidine-Suspected Fever and Its Consequences in Adult Critically Ill Patients.
Topics: Adult; Clostridioides difficile; Critical Illness; Dexmedetomidine; Fever; Humans; Hypnotics and Sedatives; Male; Retrospective Studies | 2022 |
Weaning Dexmedetomidine in Non-ICU Areas: An Implementation Effort.
Topics: Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Retrospective Studies; Substance Withdrawal Syndrome; Weaning | 2022 |
The Impact of Dexmedetomidine Initiation on Cardiovascular Status and Oxygenation in Critically ill Neonates.
Topics: Bradycardia; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature | 2022 |
More than Drug Fever: Dexmedetomidine-Induced Hyperthermia in a Critically Ill Patient.
Topics: Critical Illness; Dexmedetomidine; Drug Fever; Female; Humans; Hyperthermia, Induced; Hypnotics and Sedatives; Obesity, Morbid | 2023 |
Adverse Hemodynamic Effects of Dexmedetomidine in Critically Ill Elderly Adults.
Topics: Adult; Aged; Critical Illness; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Intensive Care Units; Respiration, Artificial; Retrospective Studies | 2023 |
Association between dexmedetomidine administration and outcomes in critically ill patients with sepsis-associated acute kidney injury.
Topics: Acute Kidney Injury; Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Intensive Care Units; Retrospective Studies; Sepsis | 2022 |
Dexmedetomidine and Propofol Sedation in Critically Ill Patients: How Much Is Too Much?
Topics: Cohort Studies; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol | 2023 |
Subjective sleep assessment compared to polysomnography in mechanically ventilated critically ill ICU patients.
Topics: Critical Illness; Dexmedetomidine; Humans; Intensive Care Units; Polysomnography; Respiration, Artificial; Sleep | 2023 |
[Sedation of critically ill patients with dexmedetomidine].
Topics: Anesthesia; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives | 2023 |
Evaluation of Dexmedetomidine as an Adjunct to Phenobarbital for Alcohol Withdrawal in Critically Ill Patients.
Topics: Adult; Alcoholism; Benzodiazepines; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Phenobarbital; Retrospective Studies; Substance Withdrawal Syndrome | 2023 |
Dexmedetomidine may reduce the risk of acute kidney injury development in critically ill patients during colistin therapy.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Colistin; Critical Illness; Dexmedetomidine; Gram-Negative Bacteria; Humans; Intensive Care Units; Retrospective Studies; Risk Factors | 2023 |
Effects of dexmedetomidine administration on outcomes in critically ill patients with acute kidney injury: A propensity score-matching analysis.
Topics: Acute Kidney Injury; Critical Illness; Dexmedetomidine; Humans; Intensive Care Units; Propensity Score; Retrospective Studies; Treatment Outcome | 2023 |
Use of dexmedetomidine in critical-ill patients: is it time to look to the actual evidence?
Topics: Critical Illness; Dexmedetomidine; Humans | 2023 |
Impact of dexmedetomidine on mortality in critically ill patients with acute kidney injury: a retrospective propensity score matching analysis.
Topics: Acute Kidney Injury; Critical Illness; Dexmedetomidine; Hospital Mortality; Humans; Intensive Care Units; Propensity Score; Retrospective Studies | 2023 |
Reconsidering Dexmedetomidine for Sedation in the Critically Ill: Implications of the SPICE III Trial.
Topics: Adult; Conscious Sedation; Critical Care; Critical Illness; Deep Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Intensive Care Units; Middle Aged; Randomized Controlled Trials as Topic; Respiration, Artificial | 2020 |
Valproic Acid for the Management of Agitation and Delirium in the Intensive Care Setting: A Retrospective Analysis.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antipsychotic Agents; Benzodiazepines; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Psychomotor Agitation; Retrospective Studies; Valproic Acid | 2020 |
Dexmedetomidine Exerts an Anti-inflammatory Effect via α2 Adrenoceptors to Prevent Lipopolysaccharide-induced Cognitive Decline in Mice.
Topics: Animals; Anti-Inflammatory Agents; Cognitive Dysfunction; Critical Illness; Dexmedetomidine; Lipopolysaccharides; Male; Mice; Receptors, Adrenergic; Rodentia; Tumor Necrosis Factor-alpha | 2020 |
Identification of risk factors for hypertension and tachycardia upon dexmedetomidine discontinuation.
Topics: Aged; Case-Control Studies; Critical Illness; Dexmedetomidine; Female; Humans; Hypertension; Hypnotics and Sedatives; Male; Middle Aged; Retrospective Studies; Risk Factors; Substance Withdrawal Syndrome; Tachycardia | 2020 |
Dexmedetomidine and Cognitive Dysfunction after Critical Illness: What Can (and Cannot) Be Extrapolated from Rodent Models.
Topics: Analgesics, Non-Narcotic; Animals; Cognitive Dysfunction; Critical Care; Critical Illness; Dexmedetomidine; Disease Models, Animal; Humans; Mice; Rodentia | 2020 |
DEXmedetomidine compared to PROpofol in NEurocritical Care [DEXPRONE]: A multicenter retrospective evaluation of clinical utility and safety.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Male; Middle Aged; Propofol; Respiration, Artificial; Retrospective Studies; Treatment Outcome | 2020 |
Evaluation of dexmedetomidine withdrawal in critically ill adults.
Topics: Adult; Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Retrospective Studies; Substance Withdrawal Syndrome | 2021 |
Could COVID delirium bring on dementia?
Topics: Cognitive Dysfunction; COVID-19; Critical Illness; Delirium; Dementia; Dexmedetomidine; Follow-Up Studies; Humans | 2020 |
Effect of Adjunctive Dexmedetomidine in the Treatment of Alcohol Withdrawal Compared to Benzodiazepine Symptom-Triggered Therapy in Critically Ill Patients: The EvADE Study.
Topics: Alcoholism; Benzodiazepines; Cohort Studies; Critical Illness; Dexmedetomidine; Ethanol; Humans; Retrospective Studies; Seizures; Substance Withdrawal Syndrome | 2022 |
Predictors of a response to dexmedetomidine in intubated, critically ill adult patients.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Intubation, Intratracheal; Respiration, Artificial; Retrospective Studies; Treatment Outcome | 2021 |
Dexmedetomidine for the treatment of delirium in the intensive care unit: do we need more evidence for adult and pediatric patients?
Topics: Adult; Child; Critical Illness; Delirium; Dexmedetomidine; Humans; Intensive Care Units | 2021 |
Dexmedetomidine and Iatrogenic Withdrawal Syndrome in Critically Ill Children.
Topics: Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Iatrogenic Disease; Substance Withdrawal Syndrome | 2021 |
Safety of dexmedetomidine for the control of agitation in critically ill traumatic brain injury patients: a descriptive study.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Behavioral Symptoms; Benzodiazepines; Body Weight; Brain Injuries, Traumatic; Comorbidity; Critical Illness; Dexmedetomidine; Drug Therapy, Combination; Female; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Retrospective Studies; Sex Factors; Substance-Related Disorders; Trauma Severity Indices | 2021 |
Safety of dexmedetomidine in the cardiac intensive care unit.
Topics: Adolescent; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Retrospective Studies | 2021 |
Are dexmedetomidine and olanzapine suitable to control delirium in critically ill elderly patients? A retrospective cohort study.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cohort Studies; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Length of Stay; Male; Olanzapine; Prognosis; Retrospective Studies; Risk Factors | 2021 |
Evaluation of Dexmedetomidine Dosing in Obese Critically Ill Patients.
Topics: Adolescent; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Pain; Respiration, Artificial | 2023 |
Trials of dexmedetomidine sedation in ventilated critically ill septic patients: Challenges, limitations and opportunities.
Topics: Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Sepsis | 2021 |
Protein Binding and Population Pharmacokinetics of Dexmedetomidine after Prolonged Infusions in Adult Critically Ill Patients.
Topics: Adult; Anti-Bacterial Agents; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Protein Binding | 2021 |
Hemodynamic and respiratory effects of dexmedetomidine sedation in critically ill Covid-19 patients: A retrospective cohort study.
Topics: COVID-19; Critical Illness; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Middle Aged; Retrospective Studies; SARS-CoV-2 | 2021 |
Dexmedetomidine in critically ill adults requiring noninvasive ventilation.
Topics: Adult; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Noninvasive Ventilation; Respiration, Artificial | 2022 |
Effects of dexmedetomidine on sleep quality of patients after surgery without mechanical ventilation in ICU.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Middle Aged; Postoperative Care; Respiratory Rate; Sleep | 2017 |
Nocturnal Dexmedetomidine in Nonintubated, Critically Ill Patients: Sleep or Sedation?
Topics: Anesthesia; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Sleep | 2017 |
Dexmedetomidine Use in a Pediatric Intensive Care Unit: A Retrospective Cohort Study.
Topics: Child; Child, Preschool; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infant; Intensive Care Units, Pediatric; Male; Respiration, Artificial; Retrospective Studies | 2018 |
Impact of Ketamine Use on Adjunctive Analgesic and Sedative Medications in Critically Ill Trauma Patients.
Topics: Adult; Analgesics; Analgesics, Opioid; Critical Illness; Dexmedetomidine; Drug Utilization; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Ketamine; Male; Middle Aged; Piperazines; Respiration, Artificial; Retrospective Studies; Thiazoles; Time Factors; Wounds and Injuries | 2017 |
Effects From Continuous Infusions of Dexmedetomidine and Propofol on Hemodynamic Stability in Critically Ill Adult Patients With Septic Shock.
Topics: Adult; Aged; Bradycardia; Critical Care; Critical Care Outcomes; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Propofol; Retrospective Studies; Shock, Septic | 2020 |
Prolonged sedation in critically ill children: is dexmedetomidine a safe option for younger age? An off-label experience.
Topics: Child, Preschool; Critical Illness; Deep Sedation; Delirium; Dexmedetomidine; Drug Interactions; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Off-Label Use; Retrospective Studies; Substance Withdrawal Syndrome | 2019 |
Dexmedetomidine Use in a Tertiary Care NICU: A Descriptive Study.
Topics: Alberta; British Columbia; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Age; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Intensive Care Units, Neonatal; Male; Retrospective Studies; Substance Withdrawal Syndrome; Tertiary Healthcare | 2019 |
Dexmedetomidine for the prevention of delirium in critically ill patients - A protocol for a systematic review.
Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Research Design; Systematic Reviews as Topic | 2019 |
Dexmedetomidine for the management of delirium in critically ill patients-A protocol for a systematic review.
Topics: Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Research Design; Systematic Reviews as Topic | 2019 |
What Is Safe Sedation in the ICU?
Topics: Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units | 2019 |
Changes in arterial blood pressure induced by passive leg raising predict hypotension during the induction of sedation in critically ill patients without severe cardiac dysfunction.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Humans; Hypotension; Leg; Male; Middle Aged; Prospective Studies; Single-Blind Method | 2013 |
Out with the old or better use of the old? A quest in sedation*.
Topics: Adrenergic alpha-2 Receptor Agonists; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Humans; Male; Respiration, Artificial | 2013 |
Influence of dexmedetomidine therapy on the management of severe alcohol withdrawal syndrome in critically ill patients.
Topics: Adult; Benzodiazepines; Blood Pressure; Critical Illness; Dexmedetomidine; Ethanol; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Male; Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome | 2014 |
Cardiovascular Effects of Continuous Dexmedetomidine Infusion Without a Loading Dose in the Pediatric Intensive Care Unit.
Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Intensive Care Units, Pediatric; Male; Pilot Projects; Prospective Studies; Treatment Outcome | 2015 |
Effects of dexmedetomidine on sleep quality in critically ill patients: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Polysomnography; Respiration, Artificial; Sleep Stages | 2014 |
Cost effectiveness of a benzodiazepine vs a nonbenzodiazepine-based sedation regimen for mechanically ventilated, critically ill adults.
Topics: Adult; Benzodiazepines; Clinical Protocols; Cost-Benefit Analysis; Critical Illness; Dexmedetomidine; Drug Costs; Humans; Hypnotics and Sedatives; Intensive Care Units; Markov Chains; Propofol; Respiration, Artificial; Sensitivity and Specificity | 2014 |
Comparison of Dexmedetomidine Versus Propofol on Hospital Costs and Length of Stay.
Topics: Adult; Aged; Conscious Sedation; Critical Care; Critical Illness; Dexmedetomidine; Female; Hospital Costs; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Propofol; Quality Improvement; Retrospective Studies; United States | 2016 |
Long-term dexmedetomidine use and safety profile among critically ill children and neonates.
Topics: Adolescent; Analgesics, Opioid; Benzodiazepines; Blood Pressure; Child; Child, Preschool; Critical Illness; Dexmedetomidine; Female; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Male; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors | 2014 |
Correlation of patient-reported outcomes of sedation and sedation assessment scores in critically ill patients.
Topics: Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male; Midazolam; Middle Aged; Patient Outcome Assessment; Patient-Centered Care; Propofol; Prospective Studies; Psychomotor Agitation; Respiration, Artificial | 2014 |
Risk Factors for Dexmedetomidine-Associated Hemodynamic Instability in Noncardiac Intensive Care Unit Patients.
Topics: Age Factors; Aged; Bradycardia; Cohort Studies; Critical Care; Critical Illness; Dexmedetomidine; Endpoint Determination; Female; Heart Rate; Hemodynamics; Humans; Hypnotics and Sedatives; Hypotension; Kaplan-Meier Estimate; Male; Middle Aged; Patients; Retrospective Studies; Risk Factors | 2016 |
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Critical Illness; Dexmedetomidine; Ethanol; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Intubation, Intratracheal; Length of Stay; Logistic Models; Lorazepam; Male; Midazolam; Middle Aged; Pneumonia; Propofol; Respiration, Artificial; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2016 |
Alcohol Withdrawal Syndrome in Critically Ill Patients: Identification, Assessment, and Management.
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Critical Illness; Dexmedetomidine; Humans; Intensive Care Units; Intubation; Syndrome | 2016 |
The pharmacokinetics of dexmedetomidine during long-term infusion in critically ill pediatric patients. A Bayesian approach with informative priors.
Topics: Algorithms; Bayes Theorem; Child; Child, Preschool; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Male; Models, Biological; Software; Time Factors | 2016 |
The relationship between sedative drug utilization and outcomes in critically ill patients undergoing mechanical ventilation.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Benzodiazepines; Critical Illness; Dexmedetomidine; Drug Utilization; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Japan; Length of Stay; Male; Middle Aged; Propofol; Respiration, Artificial | 2016 |
Corrective effect of norepinephrine on hypotension induced by dexmedetomidine in critically ill patients.
Topics: Aged; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypotension; Male; Middle Aged; Norepinephrine | 2016 |
Valproate for agitation in critically ill patients: A retrospective study.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA Agents; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Agitation; Retrospective Studies; Valproic Acid | 2017 |
Prolonged Infusion of Dexmedetomidine in Critically-ill Children.
Topics: Adolescent; Blood Pressure; Brazil; Child; Child, Preschool; Critical Illness; Dexmedetomidine; Heart Rate; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Intensive Care Units, Pediatric; Retrospective Studies; Ventilator Weaning | 2016 |
A new era for sedation in ICU patients.
Topics: Adrenergic alpha-Agonists; Conscious Sedation; Critical Illness; Dexmedetomidine; GABA Modulators; Humans; Hypnotics and Sedatives; Intensive Care Units; Midazolam; Respiration, Artificial | 2009 |
The use of dexmedetomidine in critically ill children.
Topics: Adolescent; Adult; Child; Child, Preschool; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Infant; Retrospective Studies | 2009 |
A new dosing protocol reduces dexmedetomidine-associated hypotension in critically ill surgical patients.
Topics: Adult; Aged; Bradycardia; Clinical Protocols; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Hypotension; Intensive Care Units; Male; Middle Aged; Postoperative Complications; Retrospective Studies | 2009 |
Effects of propofol and dexmedetomidine on indocyanine green elimination assessed with LIMON to patients with early septic shock: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Coloring Agents; Critical Illness; Dexmedetomidine; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Indocyanine Green; Liver Circulation; Liver Function Tests; Male; Middle Aged; Pilot Projects; Propofol; Respiration, Artificial; Shock, Septic | 2009 |
Dexmedetomidine: are tolerance and withdrawal going to be an issue with long-term infusions?.
Topics: Adrenergic alpha-Agonists; Child; Critical Illness; Dexmedetomidine; Humans; Infant; Substance Withdrawal Syndrome; Ventilator Weaning | 2010 |
The effect of dexmedetomidine on agitation during weaning of mechanical ventilation in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Critical Care; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Motor Activity; Psychomotor Agitation; Respiration, Artificial; Treatment Outcome; Ventilator Weaning; Young Adult | 2010 |
Patient-controlled sedation: a novel approach to sedation management for mechanically ventilated patients.
Topics: Analgesia, Patient-Controlled; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Infusion Pumps; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Minnesota; Pain Management; Pain Measurement; Patient Satisfaction; Pilot Projects; Respiration, Artificial; Retrospective Studies | 2010 |
Population pharmacokinetics of dexmedetomidine in infants after open heart surgery.
Topics: Aging; Algorithms; Cardiac Surgical Procedures; Cohort Studies; Computer Simulation; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Defects, Congenital; Humans; Hypnotics and Sedatives; Infant; Linear Models; Male; Models, Statistical; Nonlinear Dynamics; Population; Predictive Value of Tests; Safety | 2010 |
The complex interplay between delirium, sepsis and sedation.
Topics: Brain; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Respiration, Artificial; Sepsis | 2010 |
Dexmedetomidine in the care of critically ill patients from 2001 to 2007: an observational cohort study.
Topics: Adult; Aged; Anti-Anxiety Agents; Cohort Studies; Critical Illness; Dexmedetomidine; Female; Hospitalization; Humans; Infusions, Intravenous; Intensive Care Units; Male; Middle Aged; Retrospective Studies | 2010 |
Comment on dexmedetomidine systematic review and meta-analysis methodology.
Topics: Contraindications; Critical Illness; Data Interpretation, Statistical; Dexmedetomidine; Humans; Meta-Analysis as Topic; Respiration, Artificial; Review Literature as Topic; Treatment Outcome | 2010 |
Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients.
Topics: Aged; Cause of Death; Cohort Studies; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Kaplan-Meier Estimate; Length of Stay; Male; Midazolam; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Respiration, Artificial; Risk Assessment | 2010 |
All this confusion is killin' me.
Topics: Case-Control Studies; Conscious Sedation; Critical Care; Critical Illness; Delirium; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Male; Midazolam; Prognosis; Survival Rate; Time Factors; Treatment Outcome | 2010 |
Evaluation of dexmedetomidine: safety and clinical outcomes in critically ill trauma patients.
Topics: Adult; Analgesics; Antipsychotic Agents; Chi-Square Distribution; Critical Illness; Dexmedetomidine; Endpoint Determination; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypotension; Infusions, Intravenous; Length of Stay; Male; Middle Aged; Propofol; Registries; Respiration, Artificial; Retrospective Studies; Statistics, Nonparametric; Time Factors; Wounds and Injuries | 2011 |
Discontinuation of prolonged infusions of dexmedetomidine in critically ill children with heart disease.
Topics: Adolescent; Child; Child, Preschool; Critical Illness; Dexmedetomidine; Female; Heart Diseases; Humans; Hypnotics and Sedatives; Infant; Male; Retrospective Studies; Time Factors; Withholding Treatment | 2012 |
Hemodynamic effects of dexmedetomidine in critically ill neonates and infants with heart disease.
Topics: Child, Preschool; Critical Illness; Dexmedetomidine; Female; Heart Defects, Congenital; Hemodynamics; Humans; Hypnotics and Sedatives; Infant, Newborn; Infusions, Intravenous; Linear Models; Male; Retrospective Studies; Risk Assessment | 2012 |
The relationship between dexmedetomidine dosing and hypotension.
Topics: Adrenergic alpha-2 Receptor Agonists; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Humans; Hypotension; Incidence; Infusions, Intravenous; Intensive Care Units; Risk Factors; United States; Wounds and Injuries | 2012 |
Use of dexmedetomidine for the treatment of alcohol withdrawal syndrome in critically ill patients: a retrospective case series.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Withdrawal Delirium; Antipsychotic Agents; Benzodiazepines; Central Nervous System Depressants; Critical Care; Critical Illness; Dexmedetomidine; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Ethanol; Haloperidol; Humans; Hypnotics and Sedatives; Male; Middle Aged; Retrospective Studies; Young Adult | 2012 |
Safety and efficacy of prolonged dexmedetomidine use in critically ill children with heart disease*.
Topics: Blood Pressure; Child, Preschool; Critical Care; Critical Illness; Dexmedetomidine; Female; Heart Diseases; Heart Rate; Humans; Hypertension; Hypnotics and Sedatives; Infant; Length of Stay; Male; Midazolam; Morphine; Myocardial Contraction; Narcotics; Oxygen; Respiration, Artificial; Respiratory Rate; Retrospective Studies; Tachycardia; Time Factors | 2012 |
[Use of dexmedetomidine in a critically ill patient with hyperactive delirium: a case report].
Topics: Accidents, Traffic; Adrenergic alpha-2 Receptor Agonists; Adult; Critical Illness; Delirium; Dexmedetomidine; Embolization, Therapeutic; Emergencies; Humans; Hypnotics and Sedatives; Intensive Care Units; Liver; Male; Postoperative Complications | 2012 |
A case-based approach to the practical application of dexmedetomidine in critically ill adults.
Topics: Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Randomized Controlled Trials as Topic; Retrospective Studies | 2013 |
Medications to provide cooperation in the critically ill pediatric patient: a rose with a thorn.
Topics: Adrenergic alpha-Agonists; Adult; Child; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Propofol; Substance Withdrawal Syndrome | 2005 |