Page last updated: 2024-08-24

dexmedetomidine and Chemical and Drug Induced Liver Injury

dexmedetomidine has been researched along with Chemical and Drug Induced Liver Injury in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (90.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Ding, D; Fang, H; Kelly, R; Liu, Z; Shi, Q; Tong, W1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
He, XJ; Huang, S; Liu, MH; Xie, B1
Chou, AH; Lee, HC; Liao, CC; Liou, JT; Liu, FC1
Fan, H; Feng, X; Hu, X; Sha, J; Song, M; Wang, C; Zhang, H; Zhao, Y1
Altinbas, A; Ayhan, S; Canakci, E; Kokturk, S; Noyan, T; Tas, N1
Ao, J; He, L; Huang, Y; Li, X; Wang, A; Wang, C; Yang, C1
Deveci, E; Doğan, E; Ece, A; Güzel, A; Kaplan, İ; Şen, HS; Sen, V; Söker, S; Uluca, U1
Chen, JH; Jin, SY; Lei, DX; Song, XR; Yu, GF; Zhang, WH; Zhou, SL1
Arpaci, H; Arslan, M; Comu, FM; Kavutcu, M; Kocabiyik, M; Ozturk, L; Sezen, SC; Turgut, HC1

Reviews

1 review(s) available for dexmedetomidine and Chemical and Drug Induced Liver Injury

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for dexmedetomidine and Chemical and Drug Induced Liver Injury

ArticleYear
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Models, Biological; Predictive Value of Tests

2011
[Dexmedetomidine alleviates LPS/D-Gal-induced acute liver injury via up-regulation of LC3-II expression in mice].
    Sheng li xue bao : [Acta physiologica Sinica], 2021, Dec-25, Volume: 73, Issue:6

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Galactosamine; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Tumor Necrosis Factor-alpha; Up-Regulation

2021
The MAP2K4/JNK/c-Jun Signaling Pathway Plays A Key Role In Dexmedetomidine Protection Against Acetaminophen-Induced Liver Toxicity.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Animals; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Dose-Response Relationship, Drug; JNK Mitogen-Activated Protein Kinases; Liver; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-jun; Signal Transduction; Structure-Activity Relationship

2019
Dexmedetomidine attenuates lipopolysaccharide-induced liver oxidative stress and cell apoptosis in rats by increasing GSK-3β/MKP-1/Nrf2 pathway activity via the α2 adrenergic receptor.
    Toxicology and applied pharmacology, 2019, 02-01, Volume: 364

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Chemical and Drug Induced Liver Injury; Cytoprotection; Dexmedetomidine; Disease Models, Animal; Dual Specificity Phosphatase 1; Glycogen Synthase Kinase 3 beta; Lipopolysaccharides; Liver; Male; NF-E2-Related Factor 2; Oxidative Stress; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Signal Transduction

2019
Acute acetaminophene-induced hepatotoxicity and nephrotoxicity; therapeutic effect of dexmedetomidine.
    Bratislavske lekarske listy, 2019, Volume: 120, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Glutathione; Liver; Oxidative Stress; Rats

2019
Dexmedetomidine alleviated lipopolysaccharide/D-galactosamine-induced acute liver injury in mice.
    International immunopharmacology, 2019, Volume: 72

    Topics: Animals; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Galactosamine; Lipopolysaccharides; Liver; Male; MAP Kinase Kinase 4; Mice, Inbred BALB C; Protective Agents; Tumor Necrosis Factor-alpha

2019
Preventive effects of dexmedetomidine on the liver in a rat model of acid-induced acute lung injury.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Gene Expression Regulation; Humans; Hydrochloric Acid; Liver; Malondialdehyde; Oxidative Stress; Rats; Vascular Endothelial Growth Factor A

2014
Activation of α2 adrenoceptor attenuates lipopolysaccharide-induced hepatic injury.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:9

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Alanine Transaminase; Animals; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cytoprotection; Dexmedetomidine; Disease Models, Animal; Interleukin-1beta; Interleukin-6; Lactic Acid; Lipopolysaccharides; Liver; Male; Malondialdehyde; Oxidative Stress; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-2; Sepsis; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Yohimbine

2015
Vitamin C ameliorates high dose Dexmedetomidine induced liver injury.
    Bratislavske lekarske listy, 2016, Volume: 117, Issue:1

    Topics: Animals; Ascorbic Acid; Chemical and Drug Induced Liver Injury; Dexmedetomidine; Oxidative Stress; Protective Agents; Rats; Rats, Wistar

2016