dexmedetomidine has been researched along with Brain Injuries in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (12.12) | 29.6817 |
| 2010's | 20 (60.61) | 24.3611 |
| 2020's | 9 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Anstey, J; Bellomo, R; Jeffcote, T; Mcnamara, R; Udy, A; Weir, T | 1 |
| Gong, HS; Li, JY; Liu, MJ; You, YQ; Zhao, XC | 1 |
| Xiao, Q; Xu, J | 1 |
| Enomoto, Y; Hiramatsu, Y; Hoshino, H; Inoue, Y; Kato, H; Mathis, BJ; Matsubara, M; Matsuishi, Y; Morita, K; Shimojo, N | 1 |
| Chen, W; Huang, H; Miao, H; Su, YY; Zhang, Y | 1 |
| Chen, S; Cheng, H; Wang, J; Wu, J; Yang, X | 1 |
| Li, S; Liu, J; Wen, Q; Xie, K; Yu, J; Yu, L; Zhu, Y | 1 |
| Antonelli, M; Bello, G; Bocci, MG; Carelli, S; Caricato, A; Conti, G; Cutuli, SL; De Pascale, G; Filetici, N; Maresca, GM; Montini, L; Pizzo, CM | 1 |
| Li, Y; Liu, C; Wang, J; Yu, Z; Zhai, M; Zhang, L; Zhang, P; Zhang, Q; Zhu, H | 1 |
| Wu, Z; Xue, H; Zhang, Y; Zhao, P | 1 |
| Çınar, S; Karakaş, S; Mercantepe, T; Rakıcı, S; Saral, S; Şen, A; Topçu, A; Tümkaya, L; Yılmaz, A | 1 |
| Feng, X; Jiao, W; Ma, W; Wang, Y; Zhu, J | 1 |
| Cao, Y; Chang, Y; Dai, Z; Hu, M; Jiang, L; Lu, Y | 1 |
| Chai, X; Han, M; Huang, X; Kang, F; Li, J; Tang, C | 1 |
| Gao, W; Guo, Q; Han, L; Li, F; Liu, H; Ma, Y; Sun, D; Wang, Y; Wang, Z; Wu, Y; Xu, X; Yin, D; Zhang, J; Zhou, S | 1 |
| Gong, J; Li, X; Shen, L; Xie, Y; Zhang, R | 1 |
| Bian, GY; Hao, J; He, Y; Liu, J; Liu, T; Luo, JS; Weng, Q; Yang, MH | 1 |
| Fen, L; Ji, J; Wang, A; Wang, X | 1 |
| Miao, CH; Shi, QQ; Xiong, B | 1 |
| Bendix, I; Bührer, C; Endesfelder, S; Krain, M; Paeschke, N; Sifringer, M; Spies, CD; von Haefen, C | 1 |
| Ma, H; Ren, X; Zuo, Z | 1 |
| Jia, YP; Qiu, YS; Xu, Q | 1 |
| Blinder, H; English, S; Hutton, B; Tran, A | 1 |
| Adams, JY; Duby, JJ; Louie, EL; Schomer, KJ; Sebat, CM; Shahlaie, K | 1 |
| Bührer, C; Endesfelder, S; Makki, H; Sifringer, M; Spies, CD; von Haefen, C | 1 |
| Aal-Shaya, WA; Al-Faridi, K; Halawani, MM; Taha, WS; Tawfeeq, NA | 1 |
| Chen, PL; May, TA; Stiver, SI; Tang, EJ; Tang, JF | 1 |
| Coburn, M; Eberhardt, G; Fahlenkamp, AV; Loetscher, PD; Rex, S; Rossaint, R; Schoeler, M; Weis, J | 1 |
| Applegate, R; Benggon, M; Chen, H; Martin, R; Zhang, JH | 1 |
| Graffagnino, C; James, ML; Olson, DM | 1 |
| Ames, CP; Aryan, HE; Box, KW; Desiraju, U; Ibrahim, D | 1 |
| Goddeau, RP; Silverman, SB; Sims, JR | 1 |
| Erkonen, G; Lamb, F; Tobias, JD | 1 |
3 review(s) available for dexmedetomidine and Brain Injuries
| Article | Year |
|---|---|
The Impact of Sedative Choice on Intracranial and Systemic Physiology in Moderate to Severe Traumatic Brain Injury: A Scoping Review.
Topics: Adult; Analgesics, Opioid; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intracranial Hypertension; Ketamine; Propofol; Prospective Studies | 2023 |
The protective effects of dexmedetomidine on ischemic brain injury: A meta-analysis.
Topics: Adrenergic alpha-2 Receptor Agonists; Brain Injuries; Brain Ischemia; Dexmedetomidine; Humans; Inflammation Mediators; Intraoperative Care; Neuroprotective Agents; Neurosurgical Procedures | 2017 |
Traumatic brain injury: neuroprotective anaesthetic techniques, an update.
Topics: Adolescent; Adult; Brain Injuries; Cell Death; Central Nervous System Depressants; Craniocerebral Trauma; Cyclosporine; Dexmedetomidine; Erythropoietin; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Intracranial Hypotension; Isoflurane; Middle Aged; Neuroprotective Agents; Nitrous Oxide; Perioperative Care; Propofol; Resuscitation; Saline Solution, Hypertonic; Xenon; Young Adult | 2009 |
5 trial(s) available for dexmedetomidine and Brain Injuries
| Article | Year |
|---|---|
Effects of Dexmedetomidine-Isoflurane versus Isoflurane Anesthesia on Brain Injury After Cardiac Valve Replacement Surgery.
Topics: Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Brain Injuries; Dexmedetomidine; Drug Therapy, Combination; Female; Heart Valve Prosthesis Implantation; Humans; Inflammation Mediators; Isoflurane; Male; Middle Aged; Prospective Studies; Single-Blind Method; Treatment Outcome | 2018 |
The brain protective effect of dexmedetomidine during surgery for paediatric patients with congenital heart disease.
Topics: Brain; Brain Injuries; Child, Preschool; Dexmedetomidine; Female; Follow-Up Studies; Heart Defects, Congenital; Humans; Hypnotics and Sedatives; Male; Monitoring, Intraoperative; Organ Sparing Treatments; Prognosis; Protective Agents; Single-Blind Method | 2019 |
[Effects of dexmedetomidine on sedation and β-endorphin in traumatic brain injury: a comparative study with propofol].
Topics: Adult; beta-Endorphin; Blood Pressure; Brain Injuries; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Propofol | 2013 |
Effects of dexmedetomidine on cerebral blood flow in critically ill patients with or without traumatic brain injury: a prospective controlled trial.
Topics: Adult; Blood Pressure; Brain Injuries; Cerebrovascular Circulation; Critical Illness; Dexmedetomidine; Female; Glasgow Coma Scale; Heart Rate; Humans; Hypnotics and Sedatives; Intracranial Pressure; Male; Middle Aged; Prospective Studies; Treatment Outcome | 2013 |
A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury.
Topics: Body Temperature; Brain Injuries; Consciousness Monitors; Cross-Over Studies; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypnotics and Sedatives; Intracranial Pressure; Lactic Acid; Microdialysis; Oximetry; Pilot Projects; Propofol; Prospective Studies; Pyruvic Acid; Respiration, Artificial; Trauma Severity Indices | 2012 |
25 other study(ies) available for dexmedetomidine and Brain Injuries
| Article | Year |
|---|---|
Dexmedetomidine prevents hemorrhagic brain injury by reducing damage induced by ferroptosis in mice.
Topics: Animals; Brain Injuries; Cerebral Hemorrhage; Dexmedetomidine; Ferroptosis; Iron; Mice; Reactive Oxygen Species | 2022 |
Assessment of the effects of dexmedetomidine on outcomes of traumatic brain injury using propensity score analysis.
Topics: Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Glasgow Coma Scale; Humans; Hypotension; Propensity Score; Seizures | 2022 |
Pediatric delirium is associated with increased brain injury marker levels in cardiac surgery patients.
Topics: Adult; Bayes Theorem; Biomarkers; Brain Injuries; Cardiac Surgical Procedures; Child; Coma; Delirium; Dexmedetomidine; Humans; Infant; Infant, Newborn; Intensive Care Units; Midazolam; Prospective Studies | 2022 |
Clinical characteristics and prognosis of paroxysmal sympathetic hyperactivity in patients with severe nontraumatic brain injury.
Topics: Autonomic Nervous System Diseases; Brain Injuries; Brain Injuries, Traumatic; Dexmedetomidine; Humans; Prognosis; Prospective Studies | 2023 |
DEXMEDETOMIDINE AMELIORATES ACUTE BRAIN INJURY INDUCED BY MYOCARDIAL ISCHEMIA-REPERFUSION VIA UPREGULATING THE HIF-1 PATHWAY.
Topics: Animals; Brain Injuries; Coronary Artery Disease; Dexmedetomidine; Humans; Ischemia; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Reperfusion Injury; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction | 2023 |
Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats.
Topics: Animals; Autophagy; Brain Injuries; Dexmedetomidine; Infarction, Middle Cerebral Artery; Inflammation; JNK Mitogen-Activated Protein Kinases; Learning Disabilities; MAP Kinase Signaling System; Memory Disorders; Rats; Reperfusion Injury | 2019 |
The place of dexmedetomidine light sedation in patients with acute brain injury.
Topics: Brain Injuries; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives | 2019 |
Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Brain Injuries; Dexmedetomidine; Drug Evaluation, Preclinical; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Male; Random Allocation; Rats, Sprague-Dawley; Receptors, sigma; Reperfusion Injury; Sigma-1 Receptor | 2019 |
Dexmedetomidine alleviates neurobehavioral impairments and myelination deficits following lipopolysaccharide exposure in early postnatal rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Animals, Newborn; Behavior, Animal; Brain Injuries; Dexmedetomidine; Disease Models, Animal; Female; Gliosis; Inflammation; Lipopolysaccharides; Male; Neuroprotective Agents; Pregnancy; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor | 2020 |
Can Dexmedetomidine Be Effective in the Protection of Radiotherapy-Induced Brain Damage in the Rat?
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Avoidance Learning; Brain Injuries; Dexmedetomidine; Male; Neuroprotective Agents; Radiation Injuries, Experimental; Radiotherapy; Rats; Rats, Sprague-Dawley | 2021 |
Dexmedetomidine alleviates early brain injury following traumatic brain injury by inhibiting autophagy and neuroinflammation through the ROS/Nrf2 signaling pathway.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Autophagy; Beclin-1; Brain; Brain Injuries; Brain Injuries, Traumatic; Cell Survival; Cytokines; Dexmedetomidine; Disease Models, Animal; Female; Male; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases; Neuroprotective Agents; NF-E2-Related Factor 2; Reactive Oxygen Species; Signal Transduction | 2021 |
Dexmedetomidine attenuated early brain injury in rats with subarachnoid haemorrhage by suppressing the inflammatory response: The TLR4/NF-κB pathway and the NLRP3 inflammasome may be involved in the mechanism.
Topics: Animals; Apoptosis; Blood-Brain Barrier; Brain Edema; Brain Injuries; Dexmedetomidine; Inflammasomes; Inflammation; Male; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Signal Transduction; Subarachnoid Hemorrhage; Toll-Like Receptor 4 | 2018 |
Dexmedetomidine renders a brain protection on hippocampal formation through inhibition of nNOS-NO signalling in endotoxin-induced shock rats.
Topics: Animals; Blotting, Western; Brain Injuries; Carrier Proteins; Dexmedetomidine; Endotoxins; Hippocampus; Lipopolysaccharides; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2014 |
Neuroprotective effect of dexmedetomidine on hyperoxia-induced toxicity in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Apoptosis; Brain Injuries; Dexmedetomidine; Disease Models, Animal; Down-Regulation; Glutathione; Hyperoxia; Interleukin-1beta; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Wistar | 2015 |
Dexmedetomidine Postconditioning Reduces Brain Injury after Brain Hypoxia-Ischemia in Neonatal Rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Animals, Newborn; Brain Injuries; Cerebral Cortex; Dexmedetomidine; Dose-Response Relationship, Drug; Hypoxia-Ischemia, Brain; Ischemic Postconditioning; Maze Learning; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2016 |
[The protective effect of alpha-2 adrenergic agonist on cranial nerve in rats with brain injury].
Topics: Adrenergic Agonists; Adrenergic alpha-2 Receptor Agonists; Animals; Brain Injuries; Cranial Nerves; Dexmedetomidine; Inflammation; Interleukin-6; Male; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein beta Subunit; Tumor Necrosis Factor-alpha | 2016 |
Alpha-2 agonists for sedation in mechanically ventilated neurocritical care patients: a systematic review protocol.
Topics: Adrenergic alpha-2 Receptor Agonists; Brain Injuries; Clonidine; Conscious Sedation; Critical Care; Dexmedetomidine; Humans; Intensive Care Units; Respiration, Artificial; Systematic Reviews as Topic | 2016 |
Dexmedetomidine for Refractory Intracranial Hypertension.
Topics: Adult; Antihypertensive Agents; Brain Injuries; Dexmedetomidine; Female; Humans; Intracranial Hypertension; Male; Middle Aged; Retrospective Studies; Saline Solution, Hypertonic; Salvage Therapy; Treatment Outcome; Young Adult | 2019 |
Neuroprotective effects of dexmedetomidine against hyperoxia-induced injury in the developing rat brain.
Topics: Animals; Brain Injuries; Cell Differentiation; Cell Hypoxia; Dexmedetomidine; Female; Hippocampus; Male; Neurogenesis; Neuronal Plasticity; Neurons; Neuroprotective Agents; Oxygen; Rats; Rats, Wistar; Transcription, Genetic | 2017 |
Dexmedetomidine controls agitation and facilitates reliable, serial neurological examinations in a non-intubated patient with traumatic brain injury.
Topics: Aged; Alcoholism; Brain Injuries; Dexmedetomidine; Humans; Hypnotics and Sedatives; Male; Neurologic Examination; Psychomotor Agitation | 2011 |
Dexmedetomidine is neuroprotective in an in vitro model for traumatic brain injury.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Cell Count; Dexmedetomidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Flavonoids; Hippocampus; Hypothermia, Induced; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Organ Culture Techniques; Time Factors | 2012 |
Effect of dexmedetomidine on brain edema and neurological outcomes in surgical brain injury in rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Glucose; Blood Pressure; Brain; Brain Edema; Brain Injuries; Dexmedetomidine; Disease Models, Animal; Heart Rate; Injections, Intraperitoneal; Male; Motor Activity; Neurologic Examination; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Safety and efficacy of dexmedetomidine in neurosurgical patients.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brain Injuries; Conscious Sedation; Dexmedetomidine; Female; Heart Rate; Humans; Hypotension; Intracranial Pressure; Male; Middle Aged | 2006 |
Dexmedetomidine for the treatment of paroxysmal autonomic instability with dystonia.
Topics: Adrenergic alpha-Agonists; Adult; Autonomic Nervous System Diseases; Brain Injuries; Dexmedetomidine; Dystonia; Humans; Male | 2007 |
High-dose dexmedetomidine-induced hypertension in a child with traumatic brain injury.
Topics: Brain Injuries; Child, Preschool; Dexmedetomidine; Dose-Response Relationship, Drug; Humans; Hypertension; Hypnotics and Sedatives; Male | 2008 |