dexmedetomidine has been researched along with Anoxemia in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (6.67) | 29.6817 |
| 2010's | 21 (46.67) | 24.3611 |
| 2020's | 21 (46.67) | 2.80 |
| Authors | Studies |
|---|---|
| Leng, Y; Liu, X; Lv, J; Lv, X; Shi, Y; Zhang, M | 1 |
| Gao, Y; Yan, F | 1 |
| Wang, J; Wang, Y | 1 |
| Cai, S; Cheng, Y; Fang, J; Liu, Y; Yuan, J | 1 |
| Chen, Y; Jia, T; Liu, H; Sun, X; Wang, L; Wang, S; Xing, Z; Yao, J | 1 |
| Chen, X; Li, Z; Sun, H; Wang, T; Xia, S; Xu, Z | 1 |
| Guo, L; Wang, D; Wang, J; Yang, S; Yang, Y | 1 |
| Liu, C; Xu, R | 1 |
| Cao, L; Gao, S; Li, L; Wang, T; Yang, S | 1 |
| Fang, L; Fang, T; Li, TZ; Lin, L; Miao, HH; Shi, S; Ye, ZJ; Yu, KD | 1 |
| Chen, ZR; Hong, Y; Huang, WQ; Wen, SH; Zhan, YQ | 1 |
| Gao, H; Liu, Y; Wang, S; Yin, Y; Yu, J; Zhong, Y | 1 |
| Ayuse, T; Hara, T; Ichinomiya, T; Kazuhiko, N; Kurata, S; Kuroda, S; Mishima, G; Mori, T; Ozawa, E; Sato, S; Tatkov, S; Yano, R | 1 |
| Ji, Z; Liang, G; Wang, L; Wang, S | 1 |
| Ayer, IM; Cardoso, CG; Honsho, CS; Jorge, AT; Mattos-Junior, E | 1 |
| Liu, L; Qian, J; Song, N; Wang, Z; Xiong, W; Yang, Y; Zhou, R | 1 |
| Kyle-Sidell, C; Stockton, J | 1 |
| Cai, H; Feng, P; Su, M; Wang, X; Zhang, A; Zhang, Y | 1 |
| Gao, Q; Li, C; Wu, Z; Xu, Y; Xue, H; Zhang, Y; Zhao, P | 1 |
| Davies, R; Ma, D; Zhao, H | 1 |
| Chen, Q; Ma, WH; Su, N; Tang, ZH; Wang, X; Wang, Y; Xia, Z | 1 |
| Hao, S; Ling, Y; Liu, J; Yu, S; Zhao, Q | 1 |
| Geburek, F; Hopster, K; Hopster-Iversen, C; Kästner, SBR; Wittenberg-Voges, L | 1 |
| Chen, Q; Li, Z; Wan, L; Wu, Z; Zheng, D; Zhou, Z | 1 |
| Ito, K; Iwazaki, M; Kan, T; Kohno, M; Saito, K; Suzuki, T; Tetsu, S; Yamazaki, K | 1 |
| Beutler, SS; Tran, TT; Urman, RD | 1 |
| Cai, Y; Chen, K; Li, W | 1 |
| Chen, J; Chen, ZF; Huang, Y; Jiang, H; Zhou, JQ | 1 |
| Baghdoyan, HA; Britton, SL; Filbey, WA; Koch, LG; Lydic, R; Sanford, DT | 1 |
| Cao, H; Chen, LW; Chen, Q; Chen, YD; Hu, YN; Wu, W; Zhang, GC | 1 |
| Cai, J; Hei, Z; Luo, C; Yao, W; Yuan, D; Zhang, Y; Zhou, S | 1 |
| Bell, MT; Cleveland, JC; Foley, LS; Freeman, KA; Fullerton, DA; Herson, PS; Mares, JM; Meng, X; Puskas, F; Reece, TB; Weyant, MJ | 1 |
| Hua, X; Lin, L; Mo, L; Pan, W; Wang, Y; Yuan, F; Zhang, N | 1 |
| Bodek, D; Kern, J; Maher, J; Niazi, OT | 1 |
| Christensson, E; Ebberyd, A; Eriksson, LI; Hagel, E; Hårdemark Cedborg, A; Jonsson Fagerlund, M; Lodenius, Å; Mkrtchian, S; Scheinin, M; Ullman, J | 1 |
| Chen, J; Guo, R; Hua, X; Mo, L; Pan, W; Wang, Y | 1 |
| Kim, JY; Kim, KN; Kim, SY; Lee, HJ | 1 |
| Abdelfattach, H; Abdelhamid, D; Elhakim, M; Elsayed, A; Elshafei, M; Magdy, H | 1 |
| Dahmani, S; Gressens, P; Mantz, J; Rouelle, D | 2 |
| Akin, A; Aksu, R; Bayram, A; Bicer, C; Boyaci, A; Güler, G; Gümüş, H; Kumandas, S; Per, H | 1 |
| Do, SH; Kim, CS; Lee, EH; Lee, JH; Lee, SW; Ryu, JH | 1 |
| Chen, YS; Huang, Z; Liu, JY; Yang, ZL | 1 |
| Cho, S; Guo, H; Hara, T; Sumikawa, K; Takahashi, S; Tomiyasu, S | 1 |
| Dohi, S; Iida, H; Iida, M; Takenaka, M | 1 |
2 review(s) available for dexmedetomidine and Anoxemia
| Article | Year |
|---|---|
A systematic review and meta-analysis of the safety and efficacy of remifentanil and dexmedetomidine for awake fiberoptic endoscope intubation.
Topics: Conscious Sedation; Dexmedetomidine; Endoscopy; Fiber Optic Technology; Hemodynamics; Humans; Hypnotics and Sedatives; Hypoxia; Intubation, Intratracheal; Randomized Controlled Trials as Topic; Remifentanil | 2021 |
Moderate and deep sedation training and pharmacology for nonanesthesiologists: recommendations for effective practice.
Topics: Administration, Intravenous; Analgesics, Opioid; Anesthesiology; Apnea; Benzodiazepines; Conscious Sedation; Consciousness; Deep Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Education, Medical, Continuing; Humans; Hypnotics and Sedatives; Hypotension; Hypoventilation; Hypoxia; Practice Guidelines as Topic; Propofol | 2019 |
12 trial(s) available for dexmedetomidine and Anoxemia
| Article | Year |
|---|---|
Comparison of Intra and Post-operative Sedation Efficacy of Dexmedetomidinemidazolam and Dexmedetomidine-propofol for Major Abdominal Surgery.
Topics: Anesthesia; Apnea; Dexmedetomidine; Humans; Hypertension; Hypnotics and Sedatives; Hypotension; Hypoxia; Midazolam; Propofol; Prospective Studies | 2022 |
Research on Mechanism of miR-106a Nanoparticles Carrying Dexmedetomidine in Regulating Recovery and Metabolism of Nerve Cells in Hypoxia-Reoxygenation Injury.
Topics: Adenosine Triphosphate; bcl-2-Associated X Protein; Dexmedetomidine; Humans; Hypoxia; Interleukin-6; MicroRNAs; Nanoparticles; Neurons; NF-kappa B; Phosphocreatine; Reactive Oxygen Species; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2022 |
Clinical effects of remimazolam alone or in combination with dexmedetomidine in patients receiving bronchoscopy and influences on postoperative cognitive function: a randomized-controlled trial.
Topics: Bronchoscopy; Cognition; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypoxia; Propofol | 2023 |
Examination of stabilization of sedation by Nasal High Flow in patients with endoscopic retrograde cholangiopancreatography during sedation using Dexmedetomidine.
Topics: Adult; Carbon Dioxide; Cholangiopancreatography, Endoscopic Retrograde; Dexmedetomidine; Humans; Hypercapnia; Hypoxia; Meperidine | 2023 |
Efficacy and safety of spontaneous ventilation technique using dexmedetomidine for rigid bronchoscopic airway foreign body removal in children.
Topics: Airway Management; Anesthesia, Inhalation; Blood Pressure; Breath Holding; Bronchial Spasm; Bronchoscopy; Child, Preschool; Cough; Dexmedetomidine; Female; Foreign Bodies; Heart Rate; High-Frequency Jet Ventilation; Humans; Hypnotics and Sedatives; Hypoxia; Infant; Intraoperative Complications; Laryngeal Masks; Laryngismus; Male; Patient Safety; Preanesthetic Medication; Respiration, Artificial; Respiratory System; Treatment Outcome | 2013 |
Efficacy and safety of dexmedetomidine versus propofol for the sedation of tube-retention after oral maxillofacial surgery.
Topics: Adolescent; Adult; Anesthesia Recovery Period; Blood Pressure; Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Hypoxia; Injections, Intravenous; Intubation, Intratracheal; Middle Aged; Oral Surgical Procedures; Propofol; Young Adult | 2014 |
Sedation with Dexmedetomidine or Propofol Impairs Hypoxic Control of Breathing in Healthy Male Volunteers: A Nonblinded, Randomized Crossover Study.
Topics: Adolescent; Adult; Cross-Over Studies; Dexmedetomidine; Humans; Hypercapnia; Hypnotics and Sedatives; Hypoxia; Male; Propofol; Reference Values; Respiration; Young Adult | 2016 |
Combined use of dexmedetomidine and propofol in monitored anesthesia care: a randomized controlled study.
Topics: Airway Obstruction; Blood Pressure; Bradycardia; Dexmedetomidine; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypoxia; Infusion Pumps; Male; Middle Aged; Oxygen; Patient Satisfaction; Propofol | 2017 |
Effect of epidural dexmedetomidine on intraoperative awareness and post-operative pain after one-lung ventilation.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Non-Narcotic; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Inhalation; Awareness; Bupivacaine; Consciousness Monitors; Dexmedetomidine; Hemodynamics; Humans; Hypnotics and Sedatives; Hypoxia; Intraoperative Complications; Isoflurane; Male; Middle Aged; Pain, Postoperative; Respiration, Artificial; Single-Blind Method; Thoracic Surgical Procedures | 2010 |
The comparison of the effects of dexmedetomidine and midazolam sedation on electroencephalography in pediatric patients with febrile convulsion.
Topics: Blood Pressure; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypoxia; Infant; Male; Midazolam; Seizures, Febrile; Sleep; Treatment Outcome | 2011 |
Randomized double-blind study of remifentanil and dexmedetomidine for flexible bronchoscopy.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Blood Pressure; Bronchoscopy; Conscious Sedation; Cough; Dexmedetomidine; Double-Blind Method; Female; Heart Rate; Humans; Hypnotics and Sedatives; Hypoxia; Male; Middle Aged; Oxygen; Partial Pressure; Patient Satisfaction; Piperidines; Propofol; Remifentanil; Young Adult | 2012 |
Dexmedetomidine versus midazolam for the sedation of patients with non-invasive ventilation failure.
Topics: Aged; Cohort Studies; Cross Infection; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypoxia; Intensive Care Units; Length of Stay; Male; Midazolam; Middle Aged; Noninvasive Ventilation; Prevalence; Pulmonary Edema; Treatment Failure; Treatment Outcome; Treatment Refusal | 2012 |
31 other study(ies) available for dexmedetomidine and Anoxemia
| Article | Year |
|---|---|
Dexmedetomidine inhibits endoplasmic reticulum stress to suppress pyroptosis of hypoxia/reoxygenation-induced intestinal epithelial cells via activating the SIRT1 expression.
Topics: Apoptosis; Dexmedetomidine; Endoplasmic Reticulum Stress; Epithelial Cells; Humans; Hypoxia; Intestines; Pyroptosis; Reperfusion Injury; Signal Transduction; Sirtuin 1 | 2021 |
Circular RNA cerebellar degeneration-related protein 1 antisense RNA (Circ-CDR1as) downregulation induced by dexmedetomidine treatment protects hippocampal neurons against hypoxia/reoxygenation injury through the microRNA-28-3p (miR-28-3p)/tumor necrosis
Topics: Animals; Apoptosis; Base Sequence; Cell Line; Cell Proliferation; Dexmedetomidine; Down-Regulation; Hippocampus; Hypoxia; Inflammation; Mice; MicroRNAs; Neurons; Neuroprotective Agents; Oxygen; RNA, Circular; Signal Transduction; TNF Receptor-Associated Factor 3 | 2021 |
Dexmedetomidine protects cardiomyocytes against hypoxia/reoxygenation injury via multiple mechanisms.
Topics: Apoptosis; Catalase; Dexmedetomidine; Humans; Hypoxia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress | 2022 |
Dexmedetomidine prevents cardiomyocytes from hypoxia/reoxygenation injury via modulating tetmethylcytosine dioxygenase 1-mediated DNA demethylation of Sirtuin1.
Topics: Apoptosis; Dexmedetomidine; Dioxygenases; DNA; DNA Demethylation; Humans; Hypoxia; Methyltransferases; Mixed Function Oxygenases; Myocytes, Cardiac; Proto-Oncogene Proteins; Signal Transduction; Sirtuin 1 | 2022 |
Dexmedetomidine promotes cell proliferation and inhibits cell apoptosis by regulating LINC00982 and activating the phosphoinositide-3-kinase (PI3K)/protein kinase B (AKT) signaling in hypoxia/reoxygenation-induced H9c2 cells.
Topics: Apoptosis; Cell Proliferation; Dexmedetomidine; Humans; Hypoxia; Inflammation; Myocardial Reperfusion Injury; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Proto-Oncogene Proteins c-akt | 2022 |
Dexmedetomidine protects H9C2 rat cardiomyocytes against hypoxia/reoxygenation injury by regulating the long non-coding RNA colon cancer-associated transcript 1/microRNA-8063/Wnt/β-catenin axis.
Topics: Animals; beta Catenin; Colonic Neoplasms; Dexmedetomidine; Hypoxia; MicroRNAs; Myocytes, Cardiac; Rats; Reperfusion Injury; RNA, Long Noncoding | 2022 |
Dexmedetomidine Promotes Angiogenesis and Vasculogenic Mimicry in Human Hepatocellular Carcinoma through α
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Carcinoma, Hepatocellular; Cardiovascular Physiological Phenomena; Dexmedetomidine; Humans; Hypoxia; Liver Neoplasms; Mice; Oxygen; Receptors, Adrenergic, alpha-2; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2022 |
Dexmedetomidine Pretreatment Protects Against Myocardial Ischemia/Reperfusion Injury by Activating STAT3 Signaling.
Topics: Animals; Apoptosis; Creatine Kinase, MB Form; Dexmedetomidine; Disease Models, Animal; Hypoxia; Mice; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Receptors, Adrenergic, alpha; Reperfusion Injury; Signal Transduction | 2023 |
Dexmedetomidine suppresses hippocampal astrocyte pyroptosis in cerebral hypoxic-ischemic neonatal rats by upregulating microRNA-148a-3p to inactivate the STAT/JMJD3 axis.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspase 1; Dexmedetomidine; Glucose; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Inflammation; Ischemia; MicroRNAs; Pyroptosis; Rats | 2023 |
[Dexmedetomidine hydrochloride up-regulates expression of hypoxia inducible factor-1α to alleviate renal ischemiareperfusion injury in diabetic rats].
Topics: Animals; Dexmedetomidine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2019 |
A comparative study of the cardiopulmonary and sedative effects of a single intramuscular dose of ketamine anesthetic combinations in rabbits.
Topics: Acepromazine; Anesthesia; Anesthesia Recovery Period; Anesthetics; Animals; Arterial Pressure; Cross-Over Studies; Dexmedetomidine; Drug Combinations; Heart Rate; Hypnotics and Sedatives; Hypoxia; Injections, Intramuscular; Ketamine; Male; Midazolam; Prospective Studies; Rabbits; Respiratory Rate; Xylazine | 2020 |
Dexmedetomidine protects H9C2 against hypoxia/reoxygenation injury through miR-208b-3p/Med13/Wnt signaling pathway axis.
Topics: Apoptosis; Cell Line; Cell Survival; Dexmedetomidine; Gene Expression Regulation; Genes, Reporter; Humans; Hypoxia; Mediator Complex; MicroRNAs; Myocardial Reperfusion Injury; Myocytes, Cardiac; Protective Agents; Reperfusion Injury; Wnt Signaling Pathway | 2020 |
Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report.
Topics: COVID-19; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Hypoxia; Middle Aged; Oxygen Inhalation Therapy; SARS-CoV-2 | 2020 |
Dexmedetomidine inhibits apoptosis of astrocytes induced by oxygen-glucose deprivation via targeting JAK/STAT3 signal pathway.
Topics: Animals; Apoptosis; Astrocytes; Cell Hypoxia; Cell Survival; Dexmedetomidine; Glucose; Hypoxia; Janus Kinases; Male; Oxygen; Primary Cell Culture; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Tyrphostins | 2021 |
Dexmedetomidine post-conditioning ameliorates long-term neurological outcomes after neonatal hypoxic ischemia: The role of autophagy.
Topics: Animals; Animals, Newborn; Autophagy; Brain; Cell Death; Dexmedetomidine; Female; Hippocampus; Hypoxia; Hypoxia-Ischemia, Brain; Ischemia; Ischemic Postconditioning; Male; Microglia; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2021 |
Potential therapeutic value of dexmedetomidine in COVID-19 patients admitted to ICU.
Topics: Adrenergic alpha-2 Receptor Agonists; COVID-19; COVID-19 Drug Treatment; Cytokine Release Syndrome; Dexmedetomidine; Female; Humans; Hypoxia; Intensive Care Units; Male; Patient Admission | 2021 |
The Protective Effects of Dexmedetomidine against Hypoxia/Reoxygenation-Induced Inflammatory Injury and Permeability in Brain Endothelial Cells Mediated by Sigma-1 Receptor.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Dexmedetomidine; Endothelial Cells; Hypoxia; Infarction, Middle Cerebral Artery; Mice; Permeability; Receptors, sigma; Reperfusion Injury; Sigma-1 Receptor | 2021 |
Effects of controlled hypoxemia or hypovolemia on global and intestinal oxygenation and perfusion in isoflurane anesthetized horses receiving an alpha-2-agonist infusion.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Dexmedetomidine; Female; Heart Rate; Horses; Hypovolemia; Hypoxia; Intestinal Mucosa; Intestines; Isoflurane; Laser-Doppler Flowmetry; Male; Oxygen; Prospective Studies; Spectrophotometry; Xylazine | 2017 |
Dexmedetomidine protects hepatic cells against oxygen-glucose deprivation/reperfusion injury via lncRNA CCAT1.
Topics: Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dexmedetomidine; Glucose; Hepatocytes; Humans; Hypoxia; Liver; Oxygen; Protective Agents; Reperfusion Injury; RNA, Long Noncoding | 2018 |
Anesthetic Management in Tracheal Dilatation for Severe Tracheal Stenosis.
Topics: Aged; Anesthesia; Dexmedetomidine; Dilatation; Female; Humans; Hypoxia; Intubation, Intratracheal; Laser Therapy; Midazolam; Patient Care Team; Recurrence; Severity of Illness Index; Tracheal Stenosis | 2018 |
Eszopiclone and dexmedetomidine depress ventilation in obese rats with features of metabolic syndrome.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Azabicyclo Compounds; Body Weight; Dexmedetomidine; Eszopiclone; Hypercapnia; Hypnotics and Sedatives; Hypoxia; Metabolic Syndrome; Obesity; Piperazines; Rats; Respiration; Respiratory Mechanics; Thinness; Tidal Volume | 2014 |
Dexmedetomidine attenuates hypoxemia during palliative reconstruction of the right ventricular outflow tract in pediatric patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Blood Pressure; Cardiac Surgical Procedures; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Humans; Hypoxia; Infant; Male; Palliative Care; Pulmonary Artery; Pulmonary Atresia; Tetralogy of Fallot; Treatment Outcome; Truncus Arteriosus, Persistent | 2014 |
Dexmedetomidine protects against apoptosis induced by hypoxia/reoxygenation through the inhibition of gap junctions in NRK-52E cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Blotting, Western; Cell Communication; Cell Proliferation; Cells, Cultured; Dexmedetomidine; Flow Cytometry; Gap Junctions; HeLa Cells; Humans; Hypoxia; Kidney Tubules; Male; Oxygen; Protective Agents; Rats; Reperfusion Injury; Signal Transduction | 2015 |
Alpha-2 agonist attenuates ischemic injury in spinal cord neurons.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Apoptosis; Cardiovascular Surgical Procedures; Cell Survival; Cells, Cultured; Cytokines; Dexmedetomidine; Drug Evaluation, Preclinical; Glucose; Hypoxia; Mice, Inbred C57BL; Proto-Oncogene Proteins c-akt; Reperfusion Injury; Spinal Cord; Spinal Cord Injuries | 2015 |
Neuroprotective Effects of Dexmedetomidine Against Hypoxia-Induced Nervous System Injury are Related to Inhibition of NF-κB/COX-2 Pathways.
Topics: Animals; Caspase 3; Cyclooxygenase 2; Dexmedetomidine; Hypoxia; Male; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Signal Transduction; Trauma, Nervous System; Up-Regulation | 2016 |
Refractory Case of Paroxysmal Autonomic Instability With Dystonia Syndrome Secondary to Hypoxia.
Topics: Adrenergic alpha-2 Receptor Agonists; Autonomic Nervous System; Autonomic Nervous System Diseases; Cardiac Surgical Procedures; Dexmedetomidine; Dystonia; Electrocardiography; Humans; Hypoxia; Infusions, Intravenous; Male; Postoperative Complications; Syndrome; Young Adult | 2016 |
Dose response of dexmedetomidine‑induced resistance to hypoxia in mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Dexmedetomidine; Heart; Heart Rate; Hypnotics and Sedatives; Hypoxia; Male; Mice | 2016 |
Characterization of the postconditioning effect of dexmedetomidine in mouse organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation.
Topics: Adrenergic alpha-Agonists; Animals; Caspase 3; Cell Death; Dexmedetomidine; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Glucose; Hippocampus; Hypoxia; Imidazoline Receptors; Immunoblotting; Ischemic Preconditioning; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Phosphorylation; Receptors, Adrenergic, alpha-2; Signal Transduction | 2010 |
The effects of dexmedetomidine on left ventricular function during hypoxia and reoxygenation in isolated rat hearts.
Topics: Adrenergic alpha-Agonists; Animals; Coronary Circulation; Dexmedetomidine; Hypoxia; Male; Norepinephrine; Oxygen; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2005 |
Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions.
Topics: Adrenergic alpha-Agonists; Animals; Blotting, Western; Brain Ischemia; Caspase 3; Caspase Inhibitors; Cell Count; Cell Death; Cyclic AMP-Dependent Protein Kinases; Dexmedetomidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Glucose; Hippocampus; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Hypoxia; Ischemic Preconditioning; Male; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tyrosine | 2005 |
Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits.
Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cerebral Veins; Cerebrovascular Circulation; Clonidine; Dexmedetomidine; Hemodynamics; Hypercapnia; Hypoxia; Injections, Spinal; Pentobarbital; Rabbits; Vasodilation; Yohimbine | 2000 |