dexmedetomidine has been researched along with Aging in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 12 (63.16) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, Y; Wang, M; Wang, S; Wu, Y; Xu, X | 1 |
| Fu, Q; Liu, J; Wang, JH; Wang, PQ; Xu, ZP; Zhang, H; Zhou, XY | 1 |
| Dong, J; Guo, X; Li, L; Yang, S | 1 |
| Huang, H; Li, L; Li, P; Li, Z; Xu, B; Zhou, D | 1 |
| Chen, N; Chen, X; Qian, J; Wu, C; Xie, J | 1 |
| Han, L; Jiang, JH; Liu, MZ; Peng, YM; Qian, XL; Wang, QD; Zhang, JM; Zhang, W; Zhou, YB | 1 |
| Fels, RJ; Kenney, MJ; McMurphy, RM | 1 |
| Adachi, T; Fujisawa, S; Hongo, M; Ohba, T; Ono, K; Shibata, S; Shimbo, T | 1 |
| Aoyama, B; Kawano, T; Locatelli, FM; Nishigaki, A; Shigematsu-Locatelli, M; Tateiwa, H; Yamanaka, D; Yokoyama, M | 1 |
| Dinardo, JA; Fontaine, PJ; Mason, KP; Prescilla, R; Zgleszewski, S; Zurakowski, D | 1 |
| Adamson, PC; Barrett, JS; Gastonguay, MR; Godinez, RI; Kang, DS; Nicolson, SC; Su, F; Zuppa, AF | 1 |
| Crecelius, AR; Dinenno, FA; Kirby, BS; Voyles, WF | 1 |
| Aantaa, R; Ihmsen, H; Iirola, T; Kentala, E; Kurvinen, JP; Laitio, R; Olkkola, KT; Scheinin, M; Schüttler, J; Schwilden, H | 1 |
| Brandes, V; Ibacache, ME; Morales, AL; Muñoz, HR | 1 |
| Aliabadi, FS; Bettschart-Wolfensberger, R; Bowen, IM; Clarke, KW; Freeman, SL; Huhtinen, M; Weller, R | 1 |
| Dinenno, FA; Kirby, BS; Markwald, RR; Smith, EG; Voyles, WF | 1 |
| Donato, AJ | 1 |
| Aantaa, R; Kaisti, K; Manner, T; Olkkola, KT; Rautiainen, P; Scheinin, M; Vilo, S | 1 |
| Björklund, M; Heikkinen, T; Riekkinen, P; Sallinen, J; Scheinin, M; Siverina, I; Tanila, H | 1 |
2 trial(s) available for dexmedetomidine and Aging
| Article | Year |
|---|---|
Population pharmacokinetics of dexmedetomidine during long-term sedation in intensive care patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Conscious Sedation; Critical Care; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Hemodynamics; Humans; Hypnotics and Sedatives; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Respiration, Artificial; Young Adult | 2012 |
Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children.
Topics: Aging; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Blood Pressure; Child; Child, Preschool; Dexmedetomidine; Female; Heart Rate; Hernia, Inguinal; Humans; Hypnotics and Sedatives; Infant; Male; Methyl Ethers; Prospective Studies; Psychomotor Agitation; Sevoflurane; Sex Characteristics | 2004 |
17 other study(ies) available for dexmedetomidine and Aging
| Article | Year |
|---|---|
Cepharanthine promotes the effect of dexmedetomidine on the deposition of β-amyloid in the old age of the senile dementia rat model by regulating inflammasome expression.
Topics: Aging; Animals; Benzylisoquinolines; Brain; Dexmedetomidine; Inflammasomes; Inflammation; Male; Mitochondria; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species | 2019 |
Dexmedetomidine ameliorates postoperative cognitive dysfunction by inhibiting Toll-like receptor 4 signaling in aged mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Animals; Cell Line; Dexmedetomidine; Gene Expression Regulation; Hepatectomy; Hippocampus; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Postoperative Cognitive Complications; Signal Transduction; Spatial Memory; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
The effects of dexmedetomidine preconditioning on aged rat heart of ischaemia reperfusion injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Animals; Dexmedetomidine; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley | 2017 |
The Influence of Age on Sensitivity to Dexmedetomidine Sedation During Spinal Anesthesia in Lower Limb Orthopedic Surgery.
Topics: Adolescent; Adult; Aged; Aging; Anesthesia, Spinal; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Lower Extremity; Male; Middle Aged; Orthopedic Procedures; Young Adult | 2017 |
Dexmedetomidine protects aged rats from postoperative cognitive dysfunction by alleviating hippocampal inflammation.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Animals; Dexmedetomidine; Hippocampus; Hypnotics and Sedatives; Inflammation; Interleukin-1beta; Male; Postoperative Cognitive Complications; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2019 |
Dexmedetomidine improves early postoperative cognitive dysfunction in aged mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Anesthetics, General; Animals; Apoptosis; Apoptosis Regulatory Proteins; Behavior, Animal; Cognition Disorders; Dexmedetomidine; Dose-Response Relationship, Drug; Gene Expression Regulation; Hippocampus; Inflammation Mediators; Maze Learning; Mice, Inbred BALB C; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Neurotoxicity Syndromes; Postoperative Complications; Random Allocation; Splenectomy | 2015 |
Dexmedetomidine and regulation of splenic sympathetic nerve discharge in aged F344 rats.
Topics: Aging; Animals; Blood Pressure; Dexmedetomidine; Heart Rate; Hypnotics and Sedatives; Male; Rats, Inbred F344; Spleen; Sympathetic Nervous System | 2015 |
Age-related effects of dexmedetomidine on myocardial contraction and coronary circulation in isolated guinea pig hearts.
Topics: Adrenergic alpha-2 Receptor Agonists; Aging; Analgesics, Non-Narcotic; Animals; Coronary Circulation; Coronary Vessels; Dexmedetomidine; Guinea Pigs; Heart; Heart Rate; Hypnotics and Sedatives; In Vitro Techniques; Myocardial Contraction; Ventricular Function, Left | 2016 |
Preventive effects of dexmedetomidine on the development of cognitive dysfunction following systemic inflammation in aged rats.
Topics: Aging; Animals; Cognitive Dysfunction; Dexmedetomidine; Hippocampus; Hypnotics and Sedatives; Imidazoles; Inflammation; Isoindoles; Isoquinolines; Lipopolysaccharides; Male; Memory Disorders; Neuroprotective Agents; Piperazines; Rats; Signal Transduction | 2017 |
Incidence and predictors of hypertension during high-dose dexmedetomidine sedation for pediatric MRI.
Topics: Adolescent; Aging; Blood Pressure; Child; Child, Preschool; Cohort Studies; Conscious Sedation; Databases, Factual; Dexmedetomidine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Magnetic Resonance Imaging; Male; Predictive Value of Tests; Quality Assurance, Health Care; Risk Factors | 2010 |
Population pharmacokinetics of dexmedetomidine in infants after open heart surgery.
Topics: Aging; Algorithms; Cardiac Surgical Procedures; Cohort Studies; Computer Simulation; Critical Illness; Dexmedetomidine; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Defects, Congenital; Humans; Hypnotics and Sedatives; Infant; Linear Models; Male; Models, Statistical; Nonlinear Dynamics; Population; Predictive Value of Tests; Safety | 2010 |
Modulation of postjunctional α-adrenergic vasoconstriction during exercise and exogenous ATP infusions in ageing humans.
Topics: Adenosine; Adenosine Triphosphate; Adrenergic alpha-Agonists; Aged; Aging; Dexmedetomidine; Exercise; Female; Forearm; Hand Strength; Humans; Hyperemia; Male; Middle Aged; Muscle Contraction; Muscle, Skeletal; Phenylephrine; Ultrasonography, Doppler; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Young Adult | 2011 |
Cardiopulmonary effects and pharmacokinetics of i.v. dexmedetomidine in ponies.
Topics: Aging; Analysis of Variance; Animals; Area Under Curve; Blood Pressure; Cardiovascular System; Dexmedetomidine; Heart Rate; Horses; Hypnotics and Sedatives; Infusions, Intravenous; Partial Pressure; Respiration | 2005 |
Ageing and leg postjunctional alpha-adrenergic vasoconstrictor responsiveness in healthy men.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Aging; Blood Flow Velocity; Dexmedetomidine; Dose-Response Relationship, Drug; Femoral Artery; Humans; Laser-Doppler Flowmetry; Leg; Male; Middle Aged; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reference Values; Research Design; Sympathetic Nervous System; Tyramine; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Ageing and vascular adrenoceptor desensitization: too little, too late?
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Aging; Blood Flow Velocity; Dexmedetomidine; Femoral Artery; Humans; Leg; Male; Middle Aged; Norepinephrine; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reference Values; Sympathetic Nervous System; Tyramine; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Pharmacokinetics of intravenous dexmedetomidine in children under 11 yr of age.
Topics: Adrenergic alpha-Agonists; Aging; Bronchoscopy; Child; Child, Preschool; Conscious Sedation; Dexmedetomidine; Drug Evaluation; Female; Half-Life; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infusions, Intravenous; Magnetic Resonance Spectroscopy; Male | 2008 |
Spatial working memory improvement by an alpha2-adrenoceptor agonist dexmedetomidine is not mediated through alpha2C-adrenoceptor.
Topics: Adrenergic alpha-Agonists; Aging; Animals; Dexmedetomidine; Female; Maze Learning; Memory; Mice; Mice, Knockout; Receptors, Adrenergic, alpha-2; Spatial Behavior | 2001 |